Zinc Status as Compared to Zinc Intake and Iron Status: a Case Study of Iranian Populations from Isfahan Province

2013 ◽  
Vol 83 (6) ◽  
pp. 335-345 ◽  
Author(s):  
Nazanin Abbaspour ◽  
Rita Wegmueller ◽  
Roya Kelishadi ◽  
Rainer Schulin ◽  
Richard F. Hurrell
Keyword(s):  
Iron Status ◽  
Age Groups ◽  
Serum Zinc ◽  
Public Health Problem ◽  
Molar Ratio ◽  
Zn Deficiency ◽  
Food Groups ◽  
Food Record ◽  
Isfahan Province ◽  
Zn Status

The aim of this study was to estimate the zinc (Zn) and iron (Fe) status of different age groups in rural (Rooran) and suburban (Khomeini Shahr) populations in central Iran, to relate the Zn status to Zn intake from animal and plant foods, and to examine the relationship between Zn and Fe status. Blood samples from 341 subjects including preschool children (27), schoolchildren (157), women (91), and men (66) were analyzed for serum zinc (SZn), serum ferritin (SF), total C-reactive protein, and hemoglobin. Daily Zn and phytic acid (PA) intakes from major food groups were estimated using a 3-day weighed food record. The overall prevalence of Zn deficiency based on low SZn was 5.9 % in Rooran and 7.2 % in Khomeini Shahr. Anemia was higher in the village than in the suburb (33.5 % vs. 22.7 %; p = 0.04) and almost half of the anemia in Khomeini Shahr and 36 % in Rooran was associated with iron deficiency (ID) based on low SF. The PA:Zn molar ratio in the diet was 10 - 13, indicating a diet of moderate Zn bioavailability. About 18 % of the population consumed less Zn than their WHO Estimated Average Requirements. There was no association between Zn status and Fe status. The modest prevalence of Zn deficiency in the study populations can be explained by a relatively high Zn intake from animal source foods. Anemia however is a serious public health problem affecting some 30 % of the subjects, with almost half due to ID. The lower Fe status than Zn status could be due to the frequent consumption of tea and dairy products.

scholarly journals Poor zinc status is associated with increased risk of insulin resistance in Spanish children

2011 ◽  
Vol 107 (3) ◽  
pp. 398-404 ◽  
Author(s):  
R. M. Ortega ◽  
E. Rodríguez-Rodríguez ◽  
A. Aparicio ◽  
A. I. Jiménez ◽  
A. M. López-Sobaler ◽  
...  
Keyword(s):  
Insulin Resistance ◽  
Inverse Correlation ◽  
The Body ◽  
Zn Deficiency ◽  
Model Assessment ◽  
Food Record ◽  
Zn Concentration ◽  
Increased Risk ◽  
Serum Zn ◽  
Zn Status

Zn plays a key role in the synthesis and action of insulin. The aim of the present work was to determine whether a poorer Zn status was associated with insulin resistance in a group of 357 Spanish schoolchildren. Zn intake was determined by using a 3 d food record (i.e. Sunday to Tuesday). The body weight, height and waist and hip circumferences of all subjects were recorded and fasting plasma glucose, insulin and Zn concentrations were determined. Insulin resistance was determined using the homoeostasis model assessment (HOMA) marker. Children (11·5 %) with Zn deficiency (serum Zn concentration < 10·7 μmol/l) had higher HOMA values than those with a more satisfactory Zn status (1·73 (sd0·93)) compared with 1·38 (sd0·90;P < 0·05). An inverse correlation was found between the HOMA value and the serum Zn concentration (r− 0·149,P < 0·05). The risk of having a greater insulin resistance value (HOMA greater than the 75th percentile) increased with age (OR 1·438; 95 % CI 1·021, 2·027) and BMI (OR 1·448; 95 % CI 1·294, 1·619) and decreased as Zn serum levels increased (OR 0·908; 95 % CI 0·835, 0·987;P < 0·001). Moreover, an inverse relationship was observed between HOMA values and Zn dietary density (r− 0·122), and the Zn intakes of male children with a HOMA value of >3·16 made a significantly smaller contribution to the coverage of those recommended (59·7 (sd14·7) %) than observed in children with lower HOMA values (73·6 (sd18·2) %;P < 0·05). Taking into account that Zn intake was below than that recommended in 89·4 % of the children, it would appear that increasing the intake of Zn could improve the health and nutritional status of these children, and thus contribute to diminish problems of insulin resistance.

scholarly journals Updates on the Linoleic Acid: Dihomo-γ-Linolenic Acid Ratio (LA: DGLA)- as an Emerging Biomarker of Zinc Status (P24-019-19)

2019 ◽  
Vol 3 (Supplement_1) ◽  
Author(s):  
Elad Tako
Keyword(s):  
Linoleic Acid ◽  
Linolenic Acid ◽  
Serum Zinc ◽  
Significant Negative Correlation ◽  
Mean Value ◽  
World Health ◽  
Zn Deficiency ◽  
Acid Ratio ◽  
Zn Status

Abstract Objectives Zinc (Zn) deficiency is affecting 17% of the world's population. Although whole blood, plasma, and urine Zn decrease in severe Zn deficiency, accurate assessment of Zn status is difficult. Hence, as suggested by the World Health Organization, sensitive and specific biomarkers of Zn status are needed. Previously, we suggested the concept of the essential role of Zn for ∆6-desaturase activity. For the first time, we tested and implemented a previously unexplored biomarker of Zn status related to erythrocyte ∆6-desaturation, the LA: DGLA (linoleic acid: dihomo-γ-linolenic acid) ratio. We evaluated the sensitivity of the erythrocyte LA: DGLA ratio to changes in supplemental Zn intake. A significant negative correlation was found between dietary Zn deficiency and the LA: DGLA ratio. Our objective is to provide further and recent evidence to demonstrate that the LA: DGLA ratio is a useful and effective biomarker to assess Zn status. Methods The efficacy of the LA: DGLA ratio to predict the Zn status of subjects consuming a wheat-based diet, a representative diet of the target Zn-deficient populations, was evaluated in vivo (Gallus gallus). Two groups of birds (n = 15) were fed two different diets, a “high-Zn” diet (46.5 ppm Zn) and a “low-Zn” diet (32.8 ppm Zn), for 6 weeks. Dietary Zn intake, body weight, serum zinc, and the erythrocyte fatty acid profile were assessed. Results Serum and tissues (feather and nail) Zn concentrations were greater in the high-Zn group (P < 0.05). Duodenal expression of Zn transporters demonstrated a higher mean value in the tissues collected from the birds fed a low-Zn diet (n = 15, P < 0.05). Hepatic ∆6-desaturase expression showed a higher mean value in birds fed high-Zn diets (P < 0.05). LA: DGLA ratio was higher (P < 0.05) in the low-Zn group of birds at all-time points. Even though both groups of birds were fed Zn-deficient diets, with only 14 ppm differential in dietary Zn content, still the LA: DGLA ratio differentiated clearly between the groups, which demonstrates the sensitivity of the biomarker to change in accordance with dietary Zn intake. Conclusions Recent evidence demonstrate the potential of the LA: DGLA ratio to be used as an additional biomarker of Zn status in humans. To date, research shows that the LA: DGLA ratio corresponds to dietary Zn manipulations, both in animals and humans. Funding Sources USDA-ARS. Supporting Tables, Images and/or Graphs

scholarly journals Soil zinc, serum zinc, and the potential for agronomic biofortification to reduce human zinc deficiency in Ethiopia

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Hugo De Groote ◽  
Masresha Tessema ◽  
Samuel Gameda ◽  
Nilupa S. Gunaratna
Keyword(s):  
Nutritional Status ◽  
Zinc Deficiency ◽  
Crop Yields ◽  
Serum Zinc ◽  
Public Health Problem ◽  
Reproductive Age ◽  
Zn Deficiency ◽  
Serum Zn ◽  
Soil Zn ◽  
Child Nutritional Status

AbstractHuman zinc deficiency is a global public health problem. Many African soils are zinc deficient (ZnD), indicating fertilizers could increase crop yields and grain Zn levels, thereby increasing Zn in the food supply and alleviating human Zn deficiency. To analyze associations among soil Zn, human Zn deficiency, and child nutritional status, we combined the Ethiopian soil Zn map and the Ethiopian National Micronutrient Survey (ENMS). ENMS provides representative, georeferenced data on child nutritional status using anthropometry of children under five years old (CU5) and on human Zn deficiency among CU5 and women of reproductive age (WRA) using the recommended biomarker, serum Zn. ZnD soils mostly occur in lower altitudes, which are less populated and outside the main crop-producing areas. Serum Zn deficiencies were high, and correlated to soil Zn for children, but not for WRA. About 4 million Ethiopian CU5 are ZnD, and, of these, about 1.5 million live on low-Zn soils (< 2.5 mg/kg), while 0.3 million live on ZnD soils (< 1.5 mg/kg). Therefore, if Zn fertilizers are only applied on ZnD soils, their impact on child Zn deficiency may be limited. Greater impact is possible if Zn fertilizers are applied to soils with sufficient Zn for plant growth and if this results in increased grain Zn. Optimal soil Zn levels for plant and human nutrition may be different, and context-specific optimal levels for the latter must be determined to develop nutrition-sensitive fertilizer policies and recommendations.

scholarly journals KADAR SENG SERUM DAN RASIO MOLAR FITAT:SENG PADA ANAK USIA SEKOLAH DASAR DI PESISIR KOTA SEMARANG

2017 ◽  
Vol 6 (4) ◽  
pp. 343
Author(s):  
Ulil Albab ◽  
Aryu Candra Kusumastuti ◽  
Ninik Rustanti
Keyword(s):  
Serum Zinc ◽  
Serum Levels ◽  
Molar Ratio ◽  
School Age Children ◽  
Zinc Absorption ◽  
School Age ◽  
Food Record ◽  
Zinc Intake ◽  
Zinc Levels ◽  
Serum Zinc Levels

Background: School-age children are at risk of zinc deficiency which can be identified by measuring serum zinc levels. Zinc intake, in particular, strongly affects zinc absorption and consequently alters serum zinc concentration. Phytate is the strongest inhibitor of zinc absorption. The scale of its inhibitory ability can be measured through phytate:zinc molar ratio. This study aimed to describe phytate:zinc molar ratio in school-age children in coastal area of Semarang.Method: This was a cross-sectional study on 50 samples of children aged 9-12 years chosen by non probability sampling from several elementary schools in Semarang. Observed data include subject characteristics, zinc intake, phytate intake, and serum zinc levels. Participants' intake was assessed using 3x24 hour food recall and food record, while serum zinc levels were evaluated through Atomic Absorbant Spechtrophotomety (AAS) methods. Data was analyzed by Pearson’s test.Result: The mean serum zinc level was 93,85±22,99 µg/dl, with a phytate:zinc molar ratio of 14,48±4,23. Only 14% of the subjects had low zinc serum levels, but there was 46% with low zinc absorption rates according to their molar ratio of phytate:zinc. No significant correlation was detected between phytate:zinc molar ratio and serum zinc levels (p=0,427). Conclusion: Low zinc serum levels was found in 14% of the subjects while 46% had low zinc absorption rate. No significant correlation was detected between phytate:zinc molar ratio and serum zinc levels.

scholarly journals Assessment of Zinc and Iron Status among Malnourished Children under 5 Years Old in Gaza City

2019 ◽  
Keyword(s):  
Iron Status ◽  
Serum Zinc ◽  
Public Health Problem ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Malnourished Children ◽  
Study Population ◽  
Healthy Growth ◽  
Children Under 5

Background: Malnutrition in children often begins at birth and is associated with retarded physical and cognitive development. Micronutrients are essential for healthy growth and development. Objective: To investigate zinc and iron status among malnourished children under 5 years in Gaza city. Methodology: This cross sectional study consisted of 149 malnourished children under 5 years old from both sexes. Questionnaire interview with parents was used. Anthropometric measurements (weight, length and height) were taken. Blood samples were drawn for determination of serum Zinc and iron|. Statistical analysis was performed using SPSS version 18.0. Results: The study population was (149) cases; (53.7%) males and (46.3%) females. It was found that (61.7%) of the children were moderately underweight, (40%) of them were moderately stunted and about forty one percent (40.9%) of the study population were mildly wasted. The majority of surveyed children (91.3%) received immediate breastfeeding and more than two third (71.1%) of them were breast fed exclusively. The mean levels of serum zinc and iron were (79.8±15.6, 76.4±29.9, respectively). There were no statistically significant in zinc and iron levels according to gender, number of household, source of income, monthly income (NIS) and type of home. While there was significant association between length of breastfeeding period and serum iron levels. In contrast, there was no significant association between immediate breastfeeding, exclusive breastfeeding length of breastfeeding period, age of introducing infant formula, age of introducing complementary food with serum Zn levels. Recommendations: Childhood malnutrition among children under 5 years appears to be a public health problem in GS and interventions to improve children nutritional status must be in concern.

Trends in Dietary Intake of Vitamins A, C, and E in German Children and Adolescents – Results of the DONALD Study

2003 ◽  
Vol 73 (5) ◽  
pp. 335-342 ◽  
Author(s):  
Alexy ◽  
Kersting ◽  
Sichert-Hellert
Keyword(s):  
Vitamin E ◽  
Nutrition Education ◽  
Time Trends ◽  
Nutrient Intake ◽  
Age Groups ◽  
Food Groups ◽  
Fortified Food ◽  
Vitamin Intake ◽  
Dietary Records ◽  
The Impact

Intake of vitamins A, C, and E was evaluated and age and time trends were assessed on the basis of 3-day weighed dietary records (n = 5121) of 2- to 18-year old boys (n = 417) and girls (n = 425) enrolled in the DONALD Study (Dortmund Nutritional and Anthropometric Longitudinally Designed Study) 1986–2001. Intake of vitamin A remains stable over time, intake of vitamin C increases linearly, and intake of vitamin E follows a nonlinear trend. Age trends of vitamins A and C (per MJ) were nonlinear with a minimum at the beginning adolescence, while intake of vitamin E (per MJ) increased linearly. Girls had higher nutrient densities but lower intakes expressed as percent of reference values. Fortified food in total had a higher impact on time trends of nutrient intake than other single food groups defined here. Our results point to the impact of the food industry on long-term nutrient intake, but also underline the necessity of nutrition education even in young age groups to improve vitamin intake.

FOOD CONSUMPTION OF CHILDREN AGED 1 TO 5 IN PHUOC VINH WARD, HUE CITY BY 24 HOURS FOOD RECORDING

2015 ◽  
pp. 153-161
Author(s):  
Thi Bach Yen Hoang ◽  
Thi Hai Pham ◽  
Dinh Tuyen Hoang ◽  
Thi Huong Le ◽  
Van Thang Vo
Keyword(s):  
Total Energy ◽  
Food Consumption ◽  
Economic Status ◽  
Cross Sectional Study ◽  
Food Groups ◽  
Food Record ◽  
Related Factors ◽  
Cross Sectional ◽  
Food Consumption Survey ◽  
Food Consumed

Food consumption survey is an essential parts of nutrition surveys. It helps to determine the type and quantity of food consumed, assessing the balance of the diet, the relationship between nutrient intake and health, diseases, and economic status, culture society... There are many methods to investigate food consumption. 24-hour food record is a method that record all food consumed by the subject during previous 24 hours. Using this method in chidren helps to assess the their diet to see if it responses the demand in order to have proper nutrition. Objectives: 1. Calculating the number of each food groups consumed within 24 hours of children 1 to 5 years in Phuoc Vinh ward, Hue City; 2. Assessing the quality of their diet and some related factors. Methodology: A cross-sectional study was implemented on 200 pairs of children aged 1 to 5 and parents or caregivers living in Phuoc Vinh ward, Hue city and some related factors. Results: 82% of the children’s diets covered 4 food groups. Prevalence of glucide, protein, lipide out of the total energy intake were 44.1%, 19.5%, 36.3% respectively within group of 12-<48 months and 50%, 19.5%, 30.6% respectively within group of 48-<72 months. Total energy and protein intake were higher than demanded (p <0.05) while glucide and lipide were lower than demanded (p <0.05). Economical status of family was significant associated with variety of food (all 4 food groups) in the diet of children (p <0.05) and total energy consumed (p <0.05). Conclusion: The children did not have proper nutrition so further research need to be implemented to have suitable interventions. Key words: 24 hours food records, children aged 1 to 5, Hue city.

The Prevalence of Vitamin D Deficiency in Iran: A Literature Review

2020 ◽  
Vol 16 (7) ◽  
pp. 1015-1027
Author(s):  
Mohammad Bagherniya ◽  
Zahra Khorasanchi ◽  
Mina S. Bidokhti ◽  
Gordon A. Ferns ◽  
Mitra Rezaei ◽  
...  
Keyword(s):  
Vitamin D ◽  
Literature Review ◽  
Vitamin D Deficiency ◽  
Medical Condition ◽  
Scientific Information ◽  
Age Groups ◽  
Public Health Problem ◽  
Major Public Health Problem ◽  
Vitamin D Levels ◽  
High Prevalence

Background: Vitamin D deficiency is a common medical condition worldwide. In Iran, it has been reported that between 30-90% of people have vitamin D deficiency. However, its distribution in different parts of the country and among different age and regional groups is unclear. Therefore, the aim of this study was to review the recent literature on vitamin D deficiency in Iran. Methods: The literature review was performed using Web of Science, PubMed-Medline, Scopus and Scientific Information Database (SID) with a cut-off date of November 2016 to identify articles on vitamin D status in Iran published in the last 10 years. Studies in English and Persian that reported vitamin D levels in male and female subjects of all age groups and in healthy populations were included. Results: From 325 studies that were initially retrieved, 82 articles met the inclusion criteria. A high prevalence of vitamin D deficiency was reported, and in some regions, this was reported as >90% and was found in all age groups and in all regions of Iran. Conclusion: This review highlights the very high prevalence of vitamin D deficiency in Iran. It will be important to recognize the importance of vitamin D deficiency as a major public health problem in Iran.

scholarly journals Dietary Data in the Malmö Offspring Study–Reproducibility, Method Comparison and Validation against Objective Biomarkers

Nutrients ◽  
2021 ◽  
Vol 13 (5) ◽  
pp. 1579
Author(s):  
Sophie Hellstrand ◽  
Filip Ottosson ◽  
Einar Smith ◽  
Louise Brunkwall ◽  
Stina Ramne ◽  
...  
Keyword(s):  
Fruits And Vegetables ◽  
Method Comparison ◽  
Principal Component ◽  
Fish Intake ◽  
Dietary Intakes ◽  
Food Groups ◽  
Food Record ◽  
Fatty Fish ◽  
Lean Fish ◽  
Β Carotene

Irregular dietary intakes impairs estimations from food records. Biomarkers and method combinations can be used to improve estimates. Our aim was to examine reproducibility from two assessment methods, compare them, and validate intakes against objective biomarkers. We used the Malmö Offspring Study (55% women, 18–71 y) with data from a 4-day food record (4DFR) and a short food frequency questionnaire (SFFQ) to compare (1) repeated intakes (n = 180), (2) intakes from 4DFR and SFFQ (n = 1601), and (3) intakes of fatty fish, fruits and vegetables, and citrus with plasma biomarkers (n = 1433) (3-carboxy-4-methyl-5-propyl-2-furanpropanoic acid [CMPF], β-carotene and proline betaine). We also combined 4DFR and SFFQ estimates using principal component analysis (PCA). Moderate correlations were seen between repeated intakes (4DFR median ρ = 0.41, SFFQ median ρ = 0.59) although lower for specific 4DFR-items, especially fatty/lean fish (ρ ≤ 0.08). Between-method correlations (median ρ = 0.33) were higher for intakes of overall food groups compared to specific foods. PCA scores for citrus (proline betaine ρ = 0.53) and fruits and vegetables (β-carotene: ρ = 0.39) showed the highest biomarker correlations, whereas fatty fish intake from the SFFQ per se showed the highest correlation with CMPF (ρ = 0.46). To conclude, the reproducibility of SFFQ data was superior to 4DFR data regarding irregularly consumed foods. Method combination could slightly improve fruit and vegetable estimates, whereas SFFQ data gave most valid fatty fish intake.

scholarly journals Healthcare use prior to suicide in the Stockholm County population 2011-2016

2019 ◽  
Vol 29 (Supplement_4) ◽  
Author(s):  
J Narusyte ◽  
K Kosidou ◽  
C Dalman
Keyword(s):  
Age Groups ◽  
Public Health Problem ◽  
Major Public Health Problem ◽  
Healthcare Use ◽  
Stockholm County ◽  
Suicide Death ◽  
Death Registry ◽  
County Population ◽  
Study Population ◽  
One Year

Abstract Background Suicide is a major public health problem. A detailed description of healthcare use prior to suicide can serve to improve prevention strategies. The aim of the study was to describe the patterns of primary, specialized outpatient, and inpatient healthcare use from two weeks and up to one year prior to suicide in Stockholm County. Methods The study population included all 15 year or older suicide victims who died in Stockholm County 2011-2016 (n = 1950) identified through National Cause of Death Registry. Data on number of visits and contacts with healthcare among suicide victims were obtained from VAL healthcare use registry in Stockholm County. Healthcare use was depicted from one year to up to two weeks prior to suicide death. Results Preliminary results showed that there were 65% and 57% of women and men, respectively, who had at least one contact with healthcare during the last two weeks before suicide death. Measured one year prior to suicide, there were 93% of women and 85% of men who had at least one contact with healthcare. Among those who had at least one contact with healthcare two weeks prior to suicide, there were 16% of women and 12% of men who were hospitalized, 55% of women and 47% of men who had a contact with specialized outpatient care, and 32% of women and 27% of men who had a contact with primary healthcare. The proportion of those who did not have any contact with healthcare during the six months prior to suicide decreased gradually with increasing age among men (23% at ages of 15-24 years old and 7% at ages of 65 and older). There were on average 7% of women in all age groups who did not have any contact with healthcare during the six months prior to suicide. Conclusions The majority of the suicide victims had a contact with healthcare during the last year prior to suicide death. The findings suggest that suicide prevention efforts may target improved tools for clinically-based risk assessment. Key messages The majority of the suicide victims had at least one contact with healthcare during the last year prior to suicide death. Those who did not have any contact with healthcare during six months prior to suicide were more likely to be young men.

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