Prenatal iron containing supplements provided to Chinese women with no or mild anemia had no effect on hemoglobin concentration in post-partum women or their infants at 6 and 12 months of age

2018 ◽  
Vol 73 (11) ◽  
pp. 1473-1479 ◽  
Author(s):  
Mary K. Serdula ◽  
Yubo Zhou ◽  
Hongtian Li ◽  
Jian-meng Liu ◽  
Zuguo Mei
2014 ◽  
Vol 144 (6) ◽  
pp. 943-948 ◽  
Author(s):  
Zuguo Mei ◽  
Mary K. Serdula ◽  
Jian-meng Liu ◽  
Rafael C. Flores-Ayala ◽  
Linlin Wang ◽  
...  

2019 ◽  
Vol 2019 ◽  
pp. 1-8 ◽  
Author(s):  
Valeria C. Morales-Ancajima ◽  
Vilma Tapia ◽  
Bryan N. Vu ◽  
Yang Liu ◽  
Dulce E. Alarcón-Yaquetto ◽  
...  

Anemia affects 1.62 billion people worldwide. Although iron deficiency is the main cause of anemia, several other factors may explain its high prevalence. In this study, we sought to analyze the association between outdoor particulate matter PM2.5 levels with anemia prevalence in children aged 6–59 months residing in Lima, Peru (n = 139,368), one of the cities with the worst air pollution in Latin America. The study period was from 2012 to 2016. Anemia was defined according to the World Health Organization (Hb < 11 g/dL). PM2.5 values were estimated by a mathematical model that combined data observed from monitors, with satellite and meteorological data. PM2.5 was analyzed by quintiles. Multiple linear and logistic regressions were used to estimate the associations between hemoglobin concentration (beta) and anemia (odds ratio) with PM2.5, after adjusting by covariates. Prevalence of anemia was 39.6% (95% confidence interval (CI): 39.3–39.9). Mild anemia was observed in 30.8% of children and moderate/severe in 8.84% of children. Anemic children compared with nonanemic children are mainly males, have low body weight, higher rate of stunting, and live in an environment with high PM2.5 concentration. A slight decrease in hemoglobin (4Q B: −0.03, 95% CI: −0.05 to −0.02; 5Q B: −0.04, 95% CI: −0.06 to −0.01) and an increase in the probability of moderate/severe anemia (4Q OR: 1.18, 95% CI: 1.10–1.27; 5Q OR: 1.18, 95% CI: 1.08–1.29) were observed with increased exposure to PM2.5. We conclude that outdoor PM2.5 levels were significantly associated with decreased hemoglobin values and an increase in prevalence of moderate/severe anemia in children under 5 years old.


2019 ◽  
Vol 7 (4) ◽  
pp. 594-598
Author(s):  
Sarma Nursani Lumbanraja ◽  
Muhammad Rizki Yaznil ◽  
Dewi Indah Sari Siregar ◽  
Adriani Sakina

BACKGROUND: The prevalence of anaemia is higher among women, including pregnant women. The estimation was about 24.8% of the population in the world suffering anaemia. Anaemia during pregnancy is a big problem because it can contribute morbidity and mortality, either in mother or newborn. The impacts of anaemia during pregnancy included post-partum haemorrhage, low birth weight (LBW), preterm delivery, and low Appearance, Pulse, Grimace, Activity, Respiration (APGAR) score. AIM: This study aimed to determine the correlation between haemoglobin concentration during pregnancy and the outcome of mothers and newborns. METHODS: It was a cohort study that included 200 pregnant women in second or third trimester at antenatal care of Sundari General Hospital Outpatient Clinic on February until September 2018. The participants were interviewed using a questionnaire, and their blood was checked to measure haemoglobin concentration using portable Easy Touch Hemoglobinometer. In the next three until six months, the following investigation was conducted to assess the maternal and neonatal outcome. RESULTS: The result of this study showed among the maternal outcome, only antepartum haemoglobin concentration had a statistically significant correlation with the haemoglobin concentration during pregnancy (p < 0.05), meanwhile, among the neonatal outcome. LBW was the only factor that statistically significantly correlated to the haemoglobin concentration during pregnancy (p < 0.05). CONCLUSION: We can conclude that once anaemia occurs in pregnant women, then the women kept suffering from anaemia with its correlation was statistically significant. Keywords : hemoglobin concentration, anemia during pregnancy, maternal, neonatal outcome


2019 ◽  
Vol 3 (Supplement_1) ◽  
Author(s):  
Eric Matsiko ◽  
Alida Melse-Boonstra ◽  
Lisine Tuyisenge ◽  
Edith J M Feskens

Abstract Objectives In Rwanda, anemia affects 38% of all under five and 61% of those aged 9–11 months old; however, the contribution of diet to anemia remains less known. This study aimed to assess if dietary iron intake predicts the risk of anemia and iron deficiency among Rwandan children of 12 months old. Methods A longitudinal study of 192 children was conducted in 2016–2018 in a rural setting in Rwanda. We measured hemoglobin concentration, and collected blood samples from the infant-mother pairs at birth, 4 and 12 months post-partum. Plasma or serum ferritin, soluble transferrin receptors (sTfR), C-reactive protein (CRP), and α-Acid Glycoprotein (AGP) concentrations were measured using sandwich ELISA technique. Body iron stores were calculated from the sTfR/Ferritin ratio. Hemoglobin and ferritin values were adjusted for altitude and infection, respectively. Dietary iron intake data were collected using a full 24-hour recall, and the intake of iron from micronutrient powders was captured by questionnaire. Predictors of anemia, iron deficiency, and iron deficiency anemia at 12 months of age were modelled using Cox proportional hazard regression with robust variance. Results Anemia, iron deficiency (ID), and iron deficiency anemia (IDA) occurred in 73%, 56%, and 44% of the infants at 4 months, and 48%, 88% and 45% of the children at 12 months, respectively. For their mothers, anemia, ID, and IDA occurred in 12%, 59%, and 9% at 4 months, and 12%, 49%, and 8% at 12 months. Child's dietary iron intake did not significantly predict anemia [PR = 1.00 (0.96–1.04)], ID [PR = 0.99 (0.98–1.01)], or IDA [PR = 0.99 (0.95–1.03)] at 12 months. However, this study revealed that the child's hemoglobin concentration at birth was inversely associated with anemia at 12 months [PR = 0.92 (0.86–0.99)], whereas inflammation [PR = 1.23 (1.03–1.46)] and IDA at 4 months [PR = 1.44 (1.04–1.99)] increased the risk of anemia at 12 months. Presence of inflammation additionally predicted risk of IDA at 12 months [PR = 1.27 (1.05–1.54)]. Conclusions While dietary iron intake is not a significant predictor of anemia, 94% of anemia cases coincide with ID at 12 months of age. In addition, inflammation is the most important predictor of anemia and IDA at this age. Therefore, prevention of inflammation is crucial to make dietary measures effective. Funding Sources Embassy of the Kingdom of the Netherlands in Rwanda; UNICEF Rwanda; Nuffic.


Author(s):  
G. G. Joag ◽  
M. N. Karanjkar ◽  
Danesh B. Potdar ◽  
Jalinder M. Pawar

Anaemia in adolescent girls contributes to prenatal morbidity and mortality in the future. The present study was undertaken with the aim of studying the clinical-haematological profile of anaemia in adolescent girls in the North Indian tertiary care hospital. Among 380 adolescent girls, hemoglobin concentration was less than 12 gm/dl among 172 (45.3%) girls which was classified as anemia. 91 (52.9%) girls were classified as having mild anemia (Hb- 11.0 to 11.9 gm/dl), 69 (40.1%) had moderate anemia (Hb- 8.0 to 10.9 gm/dl) and 12 (7.0%) girls had severe anemia (Hb- less than 8 gm/dl). Most common cause of anaemia was iron deficiency anaemia. Mean  age of study participants was 14 years with Standard deviation of 2.73. In the present study, prevalence of anemia increases with increase in socio- economic class of study participants. Prevalence of anemia was more in underweight girls in comparison to those girls who had normal range of BMI.


2019 ◽  
Vol 2019 ◽  
pp. 1-7
Author(s):  
Rian Diana ◽  
Ali Khomsan ◽  
Faisal Anwar ◽  
Dyan Fajar Christianti ◽  
Rendra Kusuma ◽  
...  

Dietary diversity and quantity are important for pregnant women, particularly anemic pregnant women. This study aimed to analyze the association between dietary quantity and diversity among anemic pregnant women. This cross-sectional study was conducted in 2017 at Madura Island, Indonesia, and involved 152 anemic pregnant women. Hemoglobin concentration was analyzed by the cyanmethemoglobin method. Dietary quantity was measured by the 2 × 24 h recall. Dietary diversity was determined by Minimum Dietary Diversity for Women of Reproductive Age (MDD-W). Spearman’s rank association was performed to analyze the association between dietary diversity and quantity. The median of hemoglobin concentration was 10.1 g/dL, and 57.2% pregnant women had mild anemia. Most of the pregnant women had low adequacy levels of energy and macro- and micronutrients (except for iron). More than half (57.9%) of anemic pregnant women had reached minimum dietary diversity. Family size (p=0.048) and gestational age (p=0.004) had negative associations with dietary diversity. Dietary diversity had positive associations with energy (p=0.029), protein (p=0.003), vitamin A (p=0.001), vitamin C (p=0.004), and zinc (p=0.015) adequacy levels. Dietary diversity had no significant association with calcium (p=0.078) and iron adequacy level (p=0.206). High prevalence of mild and moderate anemia was found among pregnant women in their third trimester. Anemic pregnant women already consumed food with minimum dietary diversity but did not meet dietary quantity. Increasing dietary quantity is a priority for anemic pregnant women.


Hematology ◽  
2010 ◽  
Vol 2010 (1) ◽  
pp. 348-350 ◽  
Author(s):  
Jeffrey L. Carson ◽  
John W. Adamson

Abstract Patients with heart failure have elevated levels of circulating inflammatory cytokines and commonly have iron deficiency anemia or anemia of chronic inflammation. Clinical trials in patients with congestive heart failure and iron deficiency have demonstrated that intravenous iron treatment appears to improve subjective and objective outcomes. Most patients in these trials were not anemic or only had mild anemia, and hemoglobin concentration rose only slightly after treatment with iron. Experimental evidence demonstrates that iron is a cofactor for muscle function, which could explain the improvement in clinical outcomes. Many questions remain to be answered to understand the role of iron therapy in patients with congestive heart failure.


2019 ◽  
Vol 6 (4) ◽  
pp. 1428
Author(s):  
P. Raja ◽  
R. Rajaselvan

Background: Iron deficiency is responsible for most of the nutritional anemia. Hemoglobin concentration is a reliable indicator of anemia at the population level, as opposed to clinical measures which are subjective and therefore have more room for error. Measuring Hemoglobin concentration is relatively easy and inexpensive, and this measurement is frequently used as a proxy indicator of iron deficiency. To study the association of certain risk factors with the prevalence of anemia in school children in the age group of 8-14 years.Methods: The study was conducted from April 2017 to March 2018 in Department of Paediatrics, Government Thiruvarur Medical College, Thiruvarur. The study population consisted of school children in the age group of 8 to 14 years fulfilling the inclusion and exclusion criteria. The sample size was 250. Complete hematological investigations was done to each child for differential diagnosis of anemia.Results: Majority of the children studied had a normal BMI 38.4% (n=96), 16.8% (n=42) were classified as overweight, 9.2% (n=23) were classified as obese. 22.8% (n=57) were classified as having thinness. 12.8% (n=32) were classified as having severe thinness. Of the 132 children with anemia, majority had mild anemia 64.39% (n=85) followed by moderate 28.03% (n=37) and severe anemia 7.58% (n=10). Of the 132 children with anemia, majority had mild anemia 64.39% (n=85) followed by moderate 28.03% (n=37) and severe anemia 7.58% (n=10).Conclusions: The prevalence of anemia was significantly higher in female children (64.91%) compared to male children (42.65%). The prevalence of anemia is highest in children with severe thinness (78.13%) followed by children with obesity (73.91%). The most common type of anemia in our study was iron deficiency anemia. Majority of the children were suffering from anemia of mild severity. There was no statistically significant correlation between the prevalence of anemia in children and age and socioeconomic status.


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