Pubertal Induction of Sweat Gland Activity

1981 ◽  
Vol 60 (6) ◽  
pp. 689-692 ◽  
Author(s):  
J. Rees ◽  
S. Shuster
Keyword(s):  
Gene Expression ◽  
Sweat Gland ◽  
Sweat Rate ◽  
Adult Life ◽  
Men And Women ◽  
Normal People ◽  
Sweat Production ◽  
Before And After ◽  
Prepubertal Boys ◽  
The Difference

1. To study the difference in sweat rate between men and women the rates of cholinergic-induced sweating were measured in normal people before and after puberty and in response to androgens and anti-androgens. 2. Sweat rate in men was more than double that in women. 3. This difference did not occur in prepubertal boys and girls in whom the rate, corrected for surface area, was comparable with that in women. 4. Application or injection of androgen locally did not stimulate sweat production in the adult female. 5. Anti-androgen topically or systemically did not decrease sweat rate in men. 6. It is concluded that the rate of sweat rate in men is caused by androgen-induced gene expression at puberty and not by androgen modulation in adult life.

PENGARUH TERAPI TERTAWA TERHADAP PENURUNAN TEKANAN DARAH LANSIA DI UPT PANTI WREDHA BUDHI DHARMA YOGYAKARTA

2019 ◽  
Vol 13 (1) ◽  
Author(s):  
Niken Setyaningrum ◽  
Andri Setyorini ◽  
Fachruddin Tri Fitrianta
Keyword(s):  
Blood Pressure ◽  
Data Analysis ◽  
The Elderly ◽  
Control Group ◽  
Group Comparison ◽  
Control Blood Pressure ◽  
Men And Women ◽  
Treatment Of Hypertension ◽  
Before And After ◽  
The Difference

ABSTRACTBackground: Hypertension is one of the most common diseases, because this disease is suffered byboth men and women, as well as adults and young people. Treatment of hypertension does not onlyrely on medications from the doctor or regulate diet alone, but it is also important to make our bodyalways relaxed. Laughter can help to control blood pressure by reducing endocrine stress andcreating a relaxed condition to deal with relaxation.Objective: The general objective of the study was to determine the effect of laughter therapy ondecreasing elderly blood pressure in UPT Panti Wredha Budhi Dharma Yogyakarta.Methods: The design used in this study is a pre-experimental design study with one group pre-posttestresearch design where there is no control group (comparison). The population in this study wereelderly aged over> 60 years at 55 UPT Panti Wredha Budhi Dharma Yogyakarta. The method oftaking in this study uses total sampling. The sample in this study were 55 elderly. Data analysis wasused to determine the difference in blood pressure before and after laughing therapy with a ratio datascale that was using Pairs T-TestResult: There is an effect of laughing therapy on blood pressure in the elderly at UPT Panti WredhaBudhi Dharma Yogyakarta marked with a significant value of 0.000 (P <0.05)

Effect of physical training on peripheral sweat production

1988 ◽  
Vol 65 (2) ◽  
pp. 811-814 ◽  
Author(s):  
M. J. Buono ◽  
N. T. Sjoholm
Keyword(s):  
Physical Training ◽  
Sweat Gland ◽  
Sweat Rate ◽  
Secretory Activity ◽  
Sweat Glands ◽  
Trained Subjects ◽  
Peripheral Mechanism ◽  
Sweat Production ◽  
Sedentary Women

The purpose of this study was to determine the in vivo secretory activity of sweat glands from sedentary and trained subjects. Peripheral sweat production was determined using pilocarpine iontophoresis in 40 volunteers (10 sedentary men, 10 endurance-trained men, 10 sedentary women, 10 endurance-trained women). Peripheral sweat rate was significantly (P less than 0.05) greater in trained men [6.9 +/- 0.6 (SE) g.m2.min-1] and women (6.1 +/- 0.7) compared with sedentary men (3.1 +/- 0.5) and women (2.5 +/- 0.4). Furthermore, peripheral sweat rate was significantly correlated (r = 0.73) with maximal O2 uptake. The above two findings would suggest that physical training improves the secretory activity of the human sweat gland. Such a result supports previous findings that have suggested that the potentiation in sweating seen after training is achieved via a peripheral mechanism. In addition, several gender-related differences were found in the sudorific response of men and women. Specifically, women have a significantly greater sweat gland density, whereas men have a greater sweat production per gland.

Responses to dry heat of men and women with similar aerobic capacities

1981 ◽  
Vol 50 (1) ◽  
pp. 65-70 ◽  
Author(s):  
A. J. Frye ◽  
E. Kamon
Keyword(s):  
Heat Stress ◽  
Menstrual Cycle ◽  
Strain State ◽  
Sweat Rate ◽  
Stress Tests ◽  
Ambient Conditions ◽  
Men And Women ◽  
Dry Heat ◽  
Before And After ◽  
Cardiovascular Strain

Four men and four women with similar VO2max (56.33 +/- 4.05 and 54.08 +/- 4.27 ml.kg-1.min-1, respectively) exercised up to 3 h at 30% VO2max during heat stress tests (HST) before and after acclimation to dry heat [dry-bulb temperature (Tdb)/wet-bulb temperature (Twb) = 48/25 degrees C]. Rectal (Tre), tympanic sweat on the chest (msw), and total sweat rate (Msw) were recorded. There were no differences in the responses of the women between phases of the menstrual cycle. Tre, Tty, Tsk, and Tdb at the onset of sweating were similar in both sexes before and after acclimation. The nonacclimated men had significantly higher Msw and slower rise in Tre as compared to the nonacclimated women. Following acclimation these differences were no longer evident. Acclimation produced an increase in Msw in both sexes that was characterized by an increase in sweating sensitivity (delta msw/delta Tre). It was concluded that sex alone does not determine responses to heat stress. Consideration should also be given to the relative cardiovascular strain, state of acclimation, and the ambient conditions.

scholarly journals Is active sweating during heat acclimation required for improvements in peripheral sweat gland function?

2009 ◽  
Vol 297 (4) ◽  
pp. R1082-R1085 ◽  
Author(s):  
Michael J. Buono ◽  
Travis R. Numan ◽  
Ryan M. Claros ◽  
Stephanie K. Brodine ◽  
Fred W. Kolkhorst
Keyword(s):  
Sweat Gland ◽  
Sweat Rate ◽  
Heat Acclimation ◽  
Whole Body ◽  
Moderate Intensity ◽  
Sweat Glands ◽  
Exercise Heart Rate ◽  
Sweat Production ◽  
Gland Function ◽  
Pilocarpine Iontophoresis

We investigated whether the eccrine sweat glands must actively produce sweat during heat acclimation if they are to adapt and increase their capacity to sweat. Eight volunteers received intradermal injections of BOTOX, to prevent neural stimulation and sweat production of the sweat glands during heat acclimation, and saline injections as a control in the contralateral forearm. Subjects performed 90 min of moderate-intensity exercise in the heat (35°C, 40% relative humidity) on 10 consecutive days. Heat acclimation decreased end-exercise heart rate (156 ± 22 vs. 138 ± 17 beats/min; P = 0.0001) and rectal temperature (38.2 ± 0.3 vs. 37.9 ± 0.3°C; P = 0.0003) and increased whole body sweat rate (0.70 ± 0.29 vs. 1.06 ± 0.50 l/h; P = 0.030). During heat acclimation, there was no measurable sweating in the BOTOX-treated forearm, but the control forearm sweat rate during exercise increased 40% over the 10 days ( P = 0.040). Peripheral sweat gland function was assessed using pilocarpine iontophoresis before and after heat acclimation. Before heat acclimation, the pilocarpine-induced sweat rate of the control and BOTOX-injected forearms did not differ (0.65 ± 0.20 vs. 0.66 ± 0.22 mg·cm−2·min−1). However, following heat acclimation, the pilocarpine-induced sweat rate in the control arm increased 18% to 0.77 ± 0.21 mg·cm−2·min−1 ( P = 0.021) but decreased 52% to 0.32 ± 0.18 mg·cm−2·min−1 ( P < 0.001) in the BOTOX-treated arm. Using complete chemodenervation of the sweat glands, coupled with direct cholinergic stimulation via pilocarpine iontophoresis, we demonstrated that sweat glands must be active during heat acclimation if they are to adapt and increase their capacity to sweat.

Prolonged head-down tilt exposure reduces maximal cutaneous vasodilator and sweating capacity in humans

2003 ◽  
Vol 94 (6) ◽  
pp. 2330-2336 ◽  
Author(s):  
C. G. Crandall ◽  
M. Shibasaki ◽  
T. E. Wilson ◽  
J. Cui ◽  
B. D. Levine
Keyword(s):  
Sweat Gland ◽  
Simulated Microgravity ◽  
Sweat Rate ◽  
Bed Rest ◽  
Exercise Group ◽  
Aerobic Exercise Training ◽  
Before And After ◽  
Rate Maximum ◽  
Gland Function ◽  
Cutaneous Vascular Conductance

Cutaneous vasodilation and sweat rate are reduced during a thermal challenge after simulated and actual microgravity exposure. The effects of microgravity exposure on cutaneous vasodilator capacity and on sweat gland function are unknown. The purpose of this study was to test the hypothesis that simulated microgravity exposure, using the 6° head-down tilt (HDT) bed rest model, reduces maximal forearm cutaneous vascular conductance (FVC) and sweat gland function and that exercise during HDT preserves these responses. To test these hypotheses, 20 subjects were exposed to 14 days of strict HDT bed rest. Twelve of those subjects exercised (supine cycle ergometry) at 75% of pre-bed rest heart rate maximum for 90 min/day throughout HDT bed rest. Before and after HDT bed rest, maximal FVC was measured, via plethysmography, by heating the entire forearm to 42°C for 45 min. Sweat gland function was assessed by administering 1 × 10−6 to 2 M acetylcholine (9 doses) via intradermal microdialysis while simultaneously monitoring sweat rate over the microdialysis membranes. In the nonexercise group, maximal FVC and maximal stimulated sweat rate were significantly reduced after HDT bed rest. In contrast, these responses were unchanged in the exercise group. These data suggest that 14 days of simulated microgravity exposure, using the HDT bed rest model, reduces cutaneous vasodilator and sweating capacity, whereas aerobic exercise training during HDT bed rest preserves these responses.

TEA-sensitive K+ channels and human eccrine sweat gland output

2019 ◽  
Vol 127 (4) ◽  
pp. 921-929 ◽  
Author(s):  
Gary W. Mack ◽  
Benjamin S. Smith ◽  
Benjamin Rowland
Keyword(s):  
Electrical Stimulation ◽  
Epithelial Cells ◽  
Sweat Gland ◽  
Sweat Rate ◽  
Stimulus Frequency ◽  
Extracellular Fluid ◽  
Response Curves ◽  
Stimulus Response ◽  
Sweat Production ◽  
Eccrine Sweat

Cholinergic-activated sweating depends on an influx of Ca2+ from extracellular fluid. It is thought that the opening of K+ channels on secretory epithelial cells facilitates Ca2+ entry. We examined the hypothesis that tetraethylammonium (TEA)-sensitive K+ channels participate in sweat production. We used a pre-post experimental design and initiated cholinergic-mediated sweating with intradermal electrical stimulation, monitored local sweat rate (SR) with a small sweat capsule mounted on the skin, and delivered 50 mM TEA via intradermal microdialysis. Local SR was activated by intradermal stimulation frequencies of 0.2–64 Hz, and we generated a sigmoid-shaped stimulus-response curve by plotting the area under the SR-time curve versus log10 stimulus frequency. Peak local SR was reduced from 0.372 ± 0.331 to 0.226 ± 0.190 mg·min−1·cm−2 ( P = 0.0001) during application of 50 mM TEA, whereas the EC50 and Hill slopes were not altered. The global sigmoid-shaped stimulus-response curves for control and 50 mM TEA were significantly different ( P < 0.0001), and the plateau region was significantly reduced ( P = 0.0023) with the TEA treatment. The effect of TEA on peak local SR was similar in male and female subjects. However, we did note a small effect of sex on the shape of the stimulus-response curves during intradermal electrical stimulation. Overall, these data support the hypothesis that cholinergic control of sweat gland activity is modulated by the presence of TEA-sensitive K+ channels in human sweat gland epithelial cells. NEW & NOTEWORTHY The contribution of various potassium channels to the process of cholinergic-mediated human eccrine sweat production is unclear. Using a novel model for cholinergic-mediated sweating in humans, we provide evidence that tetraethylammonium-sensitive K+ channels (KCa1.1 and Kv channels) contribute to eccrine sweat production.

scholarly journals Estimation of Blood Pressure on Postprandial Breakfast, Meal and Dinner among Vegetarians

2021 ◽  
pp. 147-153
Author(s):  
L. S. Akshetha ◽  
R. Gayatri Devi ◽  
A. Jothi Priya
Keyword(s):  
Blood Pressure ◽  
The Body ◽  
Processed Foods ◽  
Men And Women ◽  
Snack Foods ◽  
Significant Difference ◽  
Before And After ◽  
Spss Software ◽  
The Difference ◽  
Blood Pressure Responses

Background: Blood pressure is the pressure of the blood within the arteries. Based on the circadian rhythm the BP can change. DBP can change according to age. Processed foods, canned soups, snack foods, and condiments may increase BP. The main aim of this study is to estimate the difference in postprandial BP responses during breakfast, lunch and dinner. Materials and Methods: A total of 26 healthy volunteers were randomly selected, men and women aged 17-20 for the study. Systolic blood pressure, Diastolic blood pressure, Heart rate were measured with ambulatory Blood Pressure devices every 10 min before until 90 min after each meal. The measurements were taken to identify the difference in postprandial Blood pressure responses between breakfast, lunch and dinner. Before starting the study, informed consent was taken. Data were collected and analyzed using SPSS software, independent sample T test. Results: In the present study, there was a mild increase observed before and after breakfast, lunch and dinner. There is a difference in BP before and postprandial during breakfast, lunch and dinner. In the present study, there was a mild increase observed before and after breakfast, lunch and dinner. In the morning the body releases hormones such as adrenaline and noradrenaline. These hormones boost energy which raises the BP. So there is decrease in BP before and postprandial during breakfast Conclusion: From this study only a significant difference was observed in SBP, DBP, HR of dinner. There was no significant change seen in breakfast.

scholarly journals Role of nitric oxide synthase in human sweat gland output

2020 ◽  
Vol 129 (2) ◽  
pp. 386-391
Author(s):  
Gary W. Mack
Keyword(s):  
Nitric Oxide ◽  
Nitric Oxide Synthase ◽  
Sweat Gland ◽  
Sweat Rate ◽  
Channel Blockade ◽  
Sweat Production ◽  
Local Sweat Rate ◽  
Oxide Synthase ◽  
Novel Model

The contribution of nitric oxide synthase (NOS) to the process of cholinergic-mediated human eccrine sweat production is unclear. Using a novel model for cholinergic-mediated sweating in humans, I demonstrate that blocking the NOS system led to a reduction in local sweat rate (LSR). This reduction in LSR was maintained in the presence of K+ channel blockade with tetraethylammonium.

Sweat Rate and Electrolyte Concentration in Swimmers, Runners, and Nonathletes

2010 ◽  
Vol 5 (3) ◽  
pp. 359-366 ◽  
Author(s):  
Simone D. Henkin ◽  
Paulo L. Sehl ◽  
Flavia Meyer
Keyword(s):  
Relative Humidity ◽  
Body Mass ◽  
Aquatic Environment ◽  
Electrolyte Concentration ◽  
Sweat Rate ◽  
Distilled Water ◽  
Before And After ◽  
The Difference ◽  
Similar Intensity ◽  
Maximal Cycle

Because swimmers train in an aquatic environment, they probably do not need to sweat as much as runners who train on land and, therefore, should not develop the same magnitude of sweating adaptations.Purpose:To compare sweat rate and electrolyte concentration in swimmers, runners and nonathletes.Methods:Ten swimmers (22.9 ± 3.1 years old), 10 runners (25 ± 2.9 y) and 10 nonathletes (26.5 ± 2.2 y) cycled in the heat (32°C and 40% relative humidity) for 30 min at similar intensity relative to their maximal cycle test. Sweat volume was calculated from the difference of their body mass before and after cycling, since they were not allowed to drink. Sweat was collected from the scapula using absorbent patch placed on the skin that was cleaned with distilled water. After cycling, the patch was transferred to syringe and the sample was obtained when squeezing it to a tube. Concentration of sodium ([Na+]), chloride ([Cl–]) and potassium ([K+]) were analyzed using an ion selector analyzer.Results:The sweat volume, in liters, of swimmers (0.9 ± 0.3) was lower (P < .05) than that of runners (1.5 ± 0.2) and similar to that of nonathletes (0.6 ± 0.2). [Na+] and [Cl-], in mmolL-1, of swimmers (65.4 ± 5.5 and 61.2 ± 81), and nonathletes (67.3 ± 8.5 and 58.3 ± 9.6) were higher (P < .05) than those of runners (45.2 ± 7.5 and 38.9 ± 8.3). [K+] was similar among groups.Conclusions:The lower sweat volume and higher sweat [Na+] and [Cl-] of swimmers, as compared with runners, indicate that training in the water does not cause the same magnitude of sweating adaptations.

scholarly journals Sunscreen Use and Sweat Production in Men and Women

2016 ◽  
Vol 51 (9) ◽  
pp. 696-700 ◽  
Author(s):  
Jorge Aburto-Corona ◽  
Luis Aragón-Vargas
Keyword(s):  
Sweat Rate ◽  
Control Treatment ◽  
Organic Chemical ◽  
Physically Active ◽  
Men And Women ◽  
Exercise Condition ◽  
Sweat Production ◽  
Randomized Crossover Study ◽  
Sweat Collection ◽  
Apparently Healthy

Context: Sunscreen lotions are important to protect the skin during outdoor exercise, but they may interfere with sweating. Objective: To measure the effect of 2 water-resistant sunscreens on local sweat production in men and women exercising in the heat and to compare those effects with the expected inhibition resulting from the use of an antiperspirant. Design: Randomized crossover study. Setting: Exercise in the heat (ambient temperature = 30.2°C ± 0.4°C dry bulb and 58% ± 4.3% relative humidity) in a controlled-environment laboratory. Patients or Other Participants: Twenty physically active, apparently healthy college students, 10 men (age = 22.5 ± 2.8 years, height = 1.771 ± 0.069 m, mass = 70.2 ± 11.0 kg) and 10 women (age = 22.2 ± 3.2 years, height = 1.625 ± 0.075 m, mass = 57.7 ± 7.9 kg). Intervention(s): With sweat-collection patches applied to their right and left scapular regions, the participants performed 2 exercise sessions on consecutive days. We assigned skin treatments (antiperspirant; organic chemical sun filter, sunscreen A; inorganic physical sun block, sunscreen B; no lotion) randomly to side and session. Participants pedaled at 79% ± 1% of maximum heart rate for 20 minutes in the heat. Main Outcome Measure(s): Scapular localized sweat rate. Results: No baseline, environmental, or exercise condition was different among skin treatments. Scapular localized sweat rate was lower for the antiperspirant treatment (88.3 μL/min·dm2; 95% confidence interval [CI] = 82.0, 94.7 μL/min·dm2) and the inorganic physical sun block (sunscreen B) treatment (99.3 μL/min·dm2; 95% CI = 93.1, 105.5 μL/min·dm2) than for the organic chemical sun filter (sunscreen A) treatment (114.8 μL/min·dm2; 95% CI = 108.8, 120.6 μL/min·dm2) or the no-lotion treatment (122.6 μL/min·dm2; 95% CI = 116.2, 129.0 μL/min·dm2; P &lt; .01). Conclusions: The inorganic physical sun block, sunscreen B, hindered effective sweating to the same extent as the antiperspirant, whereas the treatment with the organic chemical sun filter, sunscreen A, was not different from the control treatment. At this stage, it is not possible to identify the specific ingredient responsible for the effect.

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