scholarly journals Research of the detoxification properties of the preparation phytoglinol on the heat stress model

2020 ◽  
Vol 210 ◽  
pp. 06001
Author(s):  
Marina Semenenko ◽  
Olga Lanets ◽  
Andrey Abramov ◽  
Elena Kuzminova ◽  
Inna Zholobova
Keyword(s):  
Lipid Peroxidation ◽  
Heat Stress ◽  
Raw Materials ◽  
Antioxidant Effect ◽  
The Body ◽  
Laboratory Animals ◽  
Stress Model ◽  
Experimental Animals ◽  
The Russian Federation

The article discusses the possibility of using a new veterinary preparation phytoglinol to improve the quality of meat and dairy raw materials in the context of solving the problems of food security in the Russian Federation. An experiment conducted on laboratory animals to simulate heat stress revealed pronounced detoxification and stress-correcting properties of the preparation. The obtained results indicate that the new preparation phytoglinol not only ensures the correction of metabolic homeostasis under heat stress conditions, but also helps to weaken endotoxicosis, reduce the level of lipid peroxidation products in the body of experimental animals, thereby exhibiting a pronounced antitoxic and antioxidant effect.

scholarly journals IN VIVO ENRICHMENT OF THE LAMB OF ESSENTIAL TRACE ELEMENTS FOR ITS USE IN THE TECHNOLOGY OF FUNCTIONAL FOODS

2018 ◽  
Vol 3 (3) ◽  
pp. 74-88 ◽  
Author(s):  
Tatiana M. Giro ◽  
Ivan F. Gorlov ◽  
Marina I. Slozhenkina ◽  
Sergey V. Kozlov ◽  
Nogman V. Tasmuchanov
Keyword(s):  
Raw Materials ◽  
Daily Intake ◽  
Test Group ◽  
Zinc Content ◽  
Physiological Effect ◽  
Thyroid Stimulating Hormone ◽  
The Body ◽  
Laboratory Animals ◽  
Experimental Animals

To provide preventive measures for solving the problem of micronutrient deficiency, a new effective biologically safe method of enrichment lamb through the intervention of the cattle rations with feed supplements containing iodine and selenium in organic form has been developed. An increase in the iodine, selenium and zinc content in meat of the test animals fed enriched diets was noted, with more significant localization of elements to be registered in the meat from the ram lamb fed the «Yoddar-Zn» feed supplement together with organic selen preparation «DAFS-25» (Zn - 980 mg/100g; Se — 53.9 mg/100 g; I — 77.6 mg/100 g). So, 100 g of m. longissimus dorsi contained 8.2; 77.0 and 51.7 % of the recommended daily intake of these elements, respectively, that proved the feasibility of further output of the functional products with balanced essential nutrients. Based on the data on greater localization of microelements in meat from the ram lamb fed «Yoddar-Zn» with «DAFS-25», we made jerked snacks from the raw materials obtained from the animals of this test group. In processing, the zinc content in the product decreased by 21.3 %, iodine — 26.5 %, selenium — 16.3 % and made 771 mg/100 g, 39.72 mg/100 g, and 57.01 mg/100 g, respectively, that met the daily norm for 6.4; 56.7 and 38.0 % (for 100 g of product). In the vacuum-packed snacks, the loss of zinc was 11.3 %, iodine — 14.3 %, selenium — 12.6 % from the original content. After 3 months of storage, the zinc content in 100 g of the finished products was 5.7; selenium — 49.6; iodine — 32.6 % of the daily requirement. Investigations of physiological effect of the jerked snacks on the body of the laboratory animals were performed. Stimulating effect of selenium and iodine on the hematopoietic function of the experimental animals was revealed. The study of the functional activity of the thyroid gland found that the experimental animals’ content of thyroid stimulating hormone in blood serum was significantly higher than that of the control rats.

ECOLOGICAL AND HYGIENIC INVESTIGATION OF THE ADAPTOGENIC HERBAL PRODUCTS TO INCREASE RESISTANCE OF THE ORGANISM TO CONDITIONS OF LOW AND HIGH TEMPERATURES

2016 ◽  
Vol 1 (61) ◽  
pp. 46-51
Author(s):  
Литовченко ◽  
Ekaterina Litovchenko ◽  
Коршунова ◽  
Natalya Korshunova ◽  
Доровских ◽  
...  
Keyword(s):  
Lipid Peroxidation ◽  
High Temperatures ◽  
Malonic Dialdehyde ◽  
Antioxidant Effect ◽  
The Body ◽  
Diene Conjugates ◽  
Herbal Products ◽  
Experimental Animals ◽  
White Rats ◽  
Methodological Approaches

The purpose of this research was to study the possibility of using of food products from a mixture of Hypericum perforatum (HP) and Rhodiola rosea (RR) for the stimulation of the body´s compensatory responses to the conditions of high and low temperatures. Experiments have been conducted on experimental animals (150 white mongrel rats) in accordance with generally accepted methodological approaches. Antioxidant effects in the organism of white rats have been studied at the initiation of the processes of lipid peroxidation by the introduction of carbon tetrachloride. We were determined the products of lipid peroxidation (diene conjugates, hydroperoxides of lipids, malonic dialdehyde) for the evaluation of antioxidant effect in accordance with generally accepted methodological approaches. Researches of cold and heat adaptation reactions of experimental animals have been conducted by using the model of a long cold and heat action with appropriate climatic chambers. It was established experimentally that in doses of 150-300 mg/kg daily of the studied mixture has a strong antioxidant effect in the conditions of cold and heat stress on warm-blooded organism. The research allows to recommend a mixture of HP and RR as а regulator of adaptive reactions of the organism when exposed to low and high temperatures.

Compound feed from different producers for piglets and their comparative assessment

2021 ◽  
pp. 3-12
Author(s):  
N. I. Kulmakova ◽  
T. A. Magomadov ◽  
N. M. Kostomakhin ◽  
M. N. Dmitrieva ◽  
H. Saleh
Keyword(s):  
Raw Materials ◽  
Comparative Assessment ◽  
Feed Additives ◽  
The Body ◽  
Animal Origin ◽  
Quality And Safety ◽  
Processing Technologies ◽  
Starting Compound ◽  
Federal Standard

The quality of raw materials and goods of animal origin depends first of all on the safety of feed, their balance in terms of the main nutrients and digestibility by the body. As a rule, the lower the quality and safety of feed, the lower the productivity of all types of animals and poultry. The quality of feed is influenced by all stages of their production: growing conditions, harvesting and storage, processing technologies, canning and preparation for feeding. Where high-quality feed is used in diets, maximum productivity and high realization of the genetic potential of animals are obtained. During the storage and processing of plant and animal raw materials its physic and mechanical, biochemical, sanitary and microbiological properties change. This can be avoided only by observing the sanitary and hygienic requirements for bagging, harvesting, and storing feed. The quality of feed is confirmed by its physical, chemical, organoleptic, microbiological and other indicators, which determines the variety of feed control methods at all stages of their turnover. In this connection, the development and strengthening of control over the quality and safety of feed and feed additives is one of the important tasks of modern animal feeding science. The purpose of the work was to carried out a comparative assessment of four samples of the starting compound feed SK-3 for piglets of different producers. The experimental part of the work has been carried out in the laboratory of veterinary expertise at the compound feed plant LLC “Athens-Volga”. For the study of compound feed an average sample was taken from each sample, separating from the combined sample using a hand scoop according to Federal standard 13496.0-2016. Methods of sampling. Quality and safety control was carried out according to organoleptic, physic and chemical, microbiological indicators and the content of mycotoxins in compound feed. Monitoring of compound feed of the compared samples of the starting compound feed for piglets SK-3 according to the studied indicators has shown that all samples meet the sanitary and hygienic requirements of Federal standard of our country.

CONSUMER PROPERTIES OF PASTA WITH POWDER FROM MARIGOLD INFLORESCENCES (TAGETES L.)

2021 ◽  
Vol 40 (4) ◽  
pp. 102-112
Author(s):  
SHAPOVALOVA Nataliia ◽  
VEZHLIVTSEVA Svitlana ◽  
ANTIUSHKO Dmytro
Keyword(s):  
Raw Materials ◽  
Experimental Studies ◽  
The Body ◽  
Biologically Active Substances ◽  
Biologically Active ◽  
Organoleptic Properties ◽  
Biological Value ◽  
Plant Raw Materials ◽  
Active Substances

Background. The deficiency of essential nutrients in the human body is the root cause of reduced efficiency, general resistance of the body to various diseases. That is an urgent problem in the context of the spread of coronavirus infection. In this regard, the search for opportunities to meet the needs of the population in food products that contain biologically active substances (BAS) through the use of high-value and at the same time available plant raw materials is extremely important. Marigolds attract special attention among such raw materials. The aim of the work is to study the chemical composition and evaluate the consumer properties of Tagetes L. varieties, zoned in the Kiev region, to prove the possibility of increasing the biological value of pasta by adding to their recipe powder from marigold inflorescences. Materials and methods. The object of research is pasta of B group (noodles). Inflorescences of marigolds of different varieties gathered during the flowering period in July-September 2019–2020 in the territory of Vasylkiv and Obukhiv districts of Kyiv region, Ukraine were used as enriching plant raw materials. The quality of finished pasta was assessed by organoleptic and physicochemical indexes (moisture content and titratable acidity). The content of mineral elements in the fine powder of marigold inflorescences was determined on the EXHERT-3L device, the quantitative composition and BAS identification – by spectrophotometric analysis on the device Specord-200 Analytic Jena UV-vis. The integrated quality index of pasta products was calculated taking into account the importance factors of individual indexes. Results. Comparing the obtained results, we can state that all the studied varieties – Gold Kopfen, Orange Flame, Hawaii, Equinox are characterized by high biological value, regardless of the area of collection. As a result of calculated and experimental studies it was determined that the addition of 7 % of the supplement does not provide the required supply of vitamins and minerals. Replacing the flour in the recipe by 20 % significantly improves the mineral composition, but deteriorates the taste and aromatic properties of pasta. The most optimal and rational amount of added additive is 15 %, as it improves the organoleptic properties of pasta and enriches their BAS. Conclusion. The usage of non-traditional vegetable raw materials, in particular powder from marigold inflorescences, which is rich in biologically active substances, allows not only to expand the range, improve the quality of finished products, but also increase the biological value of the product. The optimal amount of additive –powder from marigold inflorescences, was defined. It is 15 % by weight of flour in the production of noodles. This concentration allows not only to improve the organoleptic properties, but also to increase the content of biologically active substances – vitamins, micro- and macronutrients. The usage of non-traditional natural raw materials (powder from marigold inflorescences) allows to abandon artificial colorsand give the finished pasta a pleasant colorand aroma.

scholarly journals Antioxidant effect of Mn2+ on capacitation and acrosome reaction of fresh and chilled cattle bull semen

2012 ◽  
Vol 1 (1) ◽  
pp. 18
Author(s):  
Amrit Kaur Bansal ◽  
Ranjna Sundhey Cheema ◽  
Vinod Kumar Gandotra
Keyword(s):  
Reactive Oxygen Species ◽  
Lipid Peroxidation ◽  
Acrosome Reaction ◽  
Reactive Oxygen ◽  
Antioxidant Effect ◽  
Oxygen Species ◽  
Sperm Capacitation ◽  
Bull Semen

The aim of this paper was to investigate the antioxidant effect of Mn2+ (200 mM) on the sperm capacitation and acrosome reaction of fresh and chilled cattle bull semen. It has been found that Mn2+ supplementation improves (P≤0.05) the motility at 0, 2, 4 and 6 h of incubation. MDA (malondialdehyde), end product of lipid peroxidation, decreases significantly (P≤0.05) with the supplementation of manganese at 0- and 6-hr of incubation both in fresh and chilled semen. Manganese also increases acrosome reaction significantly (P≤0.05) both in fresh and chilled semen at 0, 4 and 6 h of incubation. Therefore, our findings suggest the role of Mn2+supplementation in improving the quality of cattle bull semen by its scavenging property<em> i.e.</em> reduction in the production of reactive oxygen species during its storage at 4°C or incubation at 37°C for capacitation.

scholarly journals Use of water-alcohols treatment of medicinal plants under conditions modeling intoxication by lead and cadmium

2021 ◽  
pp. 80-88
Author(s):  
Yu. I. Koval ◽  
T. I. Bokova ◽  
A. F. Petrov
Keyword(s):  
Heavy Metals ◽  
Medicinal Plants ◽  
Blood Serum ◽  
Raw Materials ◽  
Antioxidant Properties ◽  
Live Weight ◽  
The Body ◽  
Laboratory Animals ◽  
Lead And Cadmium ◽  
Water Alcohol

The results of studying the effects of water-alcohol infusions of medicinal plants - rhizomes of thick-leafed incense (Bergenia crasslifolia L. Fritsch), dioica nettle leaves (Urtica dioca L.), burdock roots (Arctium lappa L.), and mother-and-leaf leaves - are presented. ordinary machichi (Tussilago farfara L.) on the organism of laboratory rats under conditions of short-term intoxication with heavy metals in doses of 25 mg of lead and 2.5 mg of cadmium per 1 kg of live weight. In the course of studies it was found that the effect of heavy metals on the body of laboratory animals is selective - the main “depot” of lead was bone tissue, and cadmium - the kidneys and liver. The addition of 1 ml of water-alcohol infusions from medicinal raw materials to the diet of rats as detoxicants caused a decrease in the level of lead in the animal organism to 6.32 times, cadmium to 3.46 times. The greatest detoxification ability was shown by infusions of the roots of burdock and leaves of nettle dioecious. Under the influence of elevated doses of lead and cadmium in laboratory animals there was an increase in heart mass by 40.34 % and spleen by 89.91 %, a decrease in the content of alkaline phosphatase in blood serum by 25.81 %. Water-alcohol infusions normalized the biochemical parameters of rat blood serum. Studies have shown that the infusions of rhizomes of thick-leafed frangipani, burdock roots, dioecious nettles and coltsfoot leaves with antioxidant properties can be the basis for the development of an effective herbal preparation used for the prevention and treatment of animals from intoxication with salts of heavy metals.

Effect of Bitters on the Body Weight, Lipid Profile, Catalase and Lipid Peroxidation in Experimental Animals

2012 ◽  
Vol 13 (1) ◽  
pp. 62-66 ◽  
Author(s):  
M.A. Alabi ◽  
R.M. Sunday ◽  
T. Olowokere ◽  
F.A. Kareem ◽  
F. Osanaiye
Keyword(s):  
Lipid Peroxidation ◽  
Body Weight ◽  
Lipid Profile ◽  
The Body ◽  
Experimental Animals

scholarly journals THE IMMUNOMODELING ACTIVITY OF BISMUTH CITRATE IN EXPERIMENT 1-CSTL AND LABORATORY OF INDUSTRIAL TOXICOLOGY

2019 ◽  
Vol 4 (9-10) ◽  
pp. 134-139
Author(s):  
О. I. Hrushka ◽  
V. A. Turkina ◽  
B. P. Kuzminov
Keyword(s):  
Immune System ◽  
The Body ◽  
Skin Tests ◽  
Laboratory Animals ◽  
Experimental Conditions ◽  
Experimental Animals ◽  
Bismuth Citrate ◽  
Degree Of Sensitization ◽  
Sensitizing Effect

The aim of the study. To investigate in experimental conditions the effect of bismuth citrate on the immune system of laboratory animals. Material and methods. One-time sensitization of tadpoles (subcutaneously into the ear) was performed according to the method of O.G. Alekseeva, A.I. Petkevich. The degree of sensitization was established after skin tests. Determined the leucocyte blood formula, T and B lymphocytes in peripheral blood by the rosette method, immunoglobulins of class A, M, G in serum - by the method of radial immunodiffusion of globulines in agar Difco, circulating and extracellular complexes detection of the response of blood cells to the allergen "in vitro" - by the reaction of specific leukocyte lysis. Results. Bismuth citrate causes impaired immunological homeostasis in experimental animals. Indicators of nonspecific cellular component of the immune system have changed significantly, characterizing immunocomplex pathology. A decrease in the T-helper subpopulation was observed, indicating a significant immunomodulatory ability of bismuth citrate. At the same time, there was a significant increase in cells capable of rosette formation, which suggests that bismuth citrate is capable of provoking sensitization of the body. In the humoral immunity link, significant differences in the content of circulating immune complexes in sensitized and control animals were observed. Immunoglobulin levels were unchanged relative to control. The analysis of the sensitizing effect indicates that the most probable result of sensitization of the organism in this mode of receipt of bismuth citrate is the formation of type III hypersensitivity. Conclusions. Bismuth citrate under experimental conditions causes changes in the immune system of experimental animals, which are characteristic of the allergenic response of the organism to the complement-dependent type.

scholarly journals Features of changes in the ecological situation in the Russian Federation and mechanisms for supporting the development of small towns

2017 ◽  
Vol 9 (1) ◽  
pp. 49-64
Author(s):  
Olga Malikova
Keyword(s):  
Russian Federation ◽  
Large Scale ◽  
Raw Materials ◽  
Small Towns ◽  
Ecological Situation ◽  
Urban Agglomerations ◽  
Large Cities ◽  
The Russian Federation ◽  
The Impact

The formation of large urban agglomerations makes possible to ensure more rational use of productive resources and increase labor productivity. Large cities, as a rule, have developed infrastructure and educational sector. However, there is a difficult ecological situation in many large cities. With a large scale of the city, transport accessibility is seriously complicated. From the viewpoint of favorable habitat, good ecological conditions, small and medium-sized cities often benefit from urban agglomerations. In the Russian Federation, due to the dominance of raw materials industries and the underdevelopment of local industry, small and medium-sized cities are in decline. This predetermines the need to develop special measures to support such territorial entities. The study is based on the generalization of data on the change in the ecological situation in large cities and the impact of atmospheric air pollution on the quality of life of the population. In the framework of the study, the conclusion was substantiated about the expediency of carrying out special measures aimed at improving the ecological situation in large cities and developing measures to support small and medium-sized cities. The recommendations for stimulating the development of production in small and medium-sized cities are grounded. The results of the study can find applications in the practice of regional management.

scholarly journals Metabolic processes in the small intestine wall, heart and liver in experimental intake of carrageenan

2017 ◽  
Author(s):  
O. M. Kopanytsia ◽  
M. I. Marushchak ◽  
A. A. Shcherbatyy
Keyword(s):  
Lipid Peroxidation ◽  
Small Intestine ◽  
Free Radical ◽  
Water Solution ◽  
Free Radical Oxidation ◽  
The Body ◽  
Male Rats ◽  
Free Access ◽  
Metabolic Processes ◽  
Experimental Animals

Introduction. In the scientific literature there is a large number of publications on the chemical modification of carrageenans, the relationship between the chemical structure and their biological activity, and new opportunities for their usage in medicine. That is whyit is modern to study the properties and the state of organs and systems of the body in case of carrageenan intake.The aim of the study – to learn the indices of metabolic processes in the wall of the small intestine, myocardium and liver of experimental animals using 1% carrageenan solution.Research Methods. The study was carried out on 24 white non-linear male rats. The animals of the experimental group were provided with free access to a 1.0% of carrageenan solution for 1 month. In the selected samples of the small intestine, heart and liver was evaluated the intensity of the processes of lipid peroxidation by the content of hydroperoxides and TBA-active products.Results and Discussion. It was found that the intake of a 1% solution of κ-carrageenan led to activation of lipid peroxidation both in the wall of the small intestine and in the tissues of the liver and myocardium, however, their intensity was different. The lipoperoxidation activity was highest in the small intestine wall, while the hydroperoxides and TBA-active products were less in the myocardial tissues. So, the oral usage of carrageenan in the form of a 1% water solution has a direct and indirect damaging effect on the free radical processes in the body.Conclusions. Oral administration of a 1% carrageenan solution in experimental animals leads to statistically significant activation of free radical oxidation processes in the small intestine wall, heart and liver tissues, characterized by an increase in the content of both primary and secondary products of lipoperoxidation (p<0.05).

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