Promising Medicinal Plants with Diuretic Potential Used in Brazil: State of the Art, Challenges, and Prospects

Planta Medica ◽  
2020 ◽  
Author(s):  
Priscila de Souza ◽  
Luísa Nathália Bolda Mariano ◽  
Camile Cecconi Cechinel-Zanchett ◽  
Valdir Cechinel-Filho

AbstractMedicinal plants are used in traditional medicine to treat a wide range of ailments. The knowledge of them is handed down from generation to generation and is described in several pharmacopoeia and in the general literature. The immense biodiversity of the Brazilian flora, covering about 25% of all plant species worldwide, makes Brazil a huge potential source of medicinal plants. Indeed, many of these plant species are already used in the Brazilian ethnopharmacology for their probable effect to induce diuresis, to reduce fluid retention, and to treat cardiovascular and renal disorders. This review article describes and discusses the main native Brazilian medicinal plants (including some of their isolated compounds) used as diuretics. It also gives a comprehensive analysis of the most relevant scientific studies presented to date, as well as addressing a special topic with future prospects for plant species that have not yet been scientifically studied. In brief, several plants can be indicated for more detailed study, with a view to obtain scientific subsidies for a new and effective diuretic medicine in the future. These include Bauhinia forficata, Leandra dasytricha, and Tropaeolum majus. Other species have reputed medicinal properties but lack experimental assays to demonstrate their pharmacological effects (e.g., Mikania hirsutissima, Phyllanthus niruri, and Tagetes minuta). Several active principles are indicated as responsible for the diuretic effects of the plants studied, with emphasis on phenolic compounds as flavonoids, phenolic acids, and xanthones. These results should encourage more detailed preclinical, clinical, and phytochemical investigations on Brazilian plants in the future.

2018 ◽  
Vol 25 (1) ◽  
pp. 1-14
Author(s):  
Acharya Balkrishna ◽  
◽  
Anupam Srivastava ◽  
B.K. Shukla ◽  
Rajesh Kumar Mishra ◽  
...  

During plant exploration and survey of Morni Hills, Panchkula, Haryana (2017-2018) the authors collected about 2200 field numbers from different localities. Out of them, 323 species belonging to 251 genera and 92 families are medicinal plants. The information about medicinal properties of these plants has been gathered during field trips of Morni Hills from local vaidyas and local people of remote localities. The enumeration is alphabetically arranged, followed by their family names, local/common names, plant parts used for curing diseases and medicinal uses. These plant species are utilized by local people against various diseases in Morni Hills area.


Agriculture ◽  
2021 ◽  
Vol 11 (11) ◽  
pp. 1136
Author(s):  
Alessandra Durazzo ◽  
Massimo Lucarini ◽  
Manuela Plutino ◽  
Giuseppe Pignatti ◽  
Ioannis K. Karabagias ◽  
...  

Plant species are fundamental source of nectar in beekeeping since bees access nectar and pollen from flowers. Consequently, bee products are strongly linked to the bee foraging flora source, and, depending on this, they acquire defined features, including their health and medicinal properties. Medicinal plants contribute greatly to increase the beneficial properties of bee products, such as honey, pollen, royal jelly, and propolis. Bee products represent a potential source of natural antioxidants that can counteract the effects of oxidative stress underlying the pathogenesis of many diseases. The antioxidant properties of bee products have been widely studied and there is an abundance of information available in the literature. Notwithstanding, the uniqueness of the presented perspective is to provide an updated overview of the antioxidant properties of bee products derived from medicinal plants as beekeeping sources. This topic is divided and discussed in the text in different sections as follows: (i) beekeeping and the impacts of environmental factors; (ii) an overview of the role of medicinal plants for bee products; (iii) definition and categorization of the main medicinal bee plants and related bee products; (iv) the study approach of the antioxidant properties; (v) the conventional and innovative assays used for the measurement of the antioxidant activity; and (vi) the antioxidant properties of bee products from medicinal plants.


2021 ◽  
Vol 12 ◽  
Author(s):  
Dereje Nigussie ◽  
Gail Davey ◽  
Takele Beyene Tufa ◽  
Malcolm Brewster ◽  
Belete Adefris Legesse ◽  
...  

Background: Podoconiosis and lymphatic filariasis are the most common causes of lower limb lymphoedema in the tropics. Many sufferers experience frequent painful episodes of acute bacterial infection. Plant based traditional medicines are used to treat infections in many countries and are culturally established in Ethiopia. Ethiopian medicinal plants found to have antibacterial and antifungal activities were reviewed with the aim of increasing information about the treatment of wound infections in patients with lymphoedema.Methods: This study collates data from published articles on medicinal plants with antibacterial and antifungal activities in Ethiopia. A systematic search of Scopus, EMBASE, PUBMED/MEDLINE and Google Scholar was undertaken. The Preferred Reporting Items for Systematic Reviews and Meta-analysis (PRISMA) guidelines were followed. The protocol was registered on PROSPERO with registration number CRD42019127471. All controlled studies of in vitro antibacterial and antifungal activities were considered. All articles containing the descriptors published until June 28, 2019 were included. The outcome was measured as percent inhibition of microbial growth. For quality assessment of individual in vitro studies, OECD guidelines and the WHO-Good Laboratory Practice (GLP) handbook were used.Results: Seventy-nine studies met the inclusion criteria. A total of 150 plant species and three compounds had been tested against 42 species of bacteria, while 43 plant species had been tested against 22 species of fungus.Conclusion: Materials derived from several Ethiopian medicinal plants have been shown to have promising activity against a variety of bacteria and fungi. Those derived from Azadiractha indica A. Juss. and Lawsonia inerms L. are the most extensively studied against a wide range of gram-negative and positive bacteria, and fungal species.


2021 ◽  
Vol 49 (1) ◽  
Author(s):  
Savina Asiimwe ◽  
Jane Namukobe ◽  
Robert Byamukama ◽  
Betty Imalingat

Abstract Background Medicinal plants form an integral part of many health care systems in Uganda. This study aimed at documenting the therapeutic importance of plant species used in primary health care among communities living adjacent to Mabira and Mpanga forest reserves in Central Uganda. Methods An ethnobotanical study was conducted between April and June 2018 in 7 villages adjacent to Mpanga and 6 villages adjacent to Mabira central forest reserves. Information was obtained from 28 respondents identified using snowball and purposive sampling techniques and interviewed using semi-structured questionnaires. Descriptive statistics were used to present the data. The quantitative analysis of data was done using fidelity level, informant consensus factor, and percent respondent knowledge indices. Results A total of 136 medicinal plants were recorded. The plant species classified into 55 families were grouped under 14 medical categories with the highest number of plant species being used for digestive disorders (44%), followed by respiratory (38%) and dermatological disorders (36%). Hoslundia opposita Vahl was mentioned by 71% of the respondents for treating 22 disease conditions. Plant Family Fabaceae was the most represented with 16 species. Informant consensus agreement was high (0.7) for respiratory disorders. The fidelity level was 100% for Bidens pilosa L. and Callistemon citrinus Skeels for treating wounds and cough, respectively. Plant remedies were mainly prepared by decoction (31%) and administered orally (36%). A large number of plants (61%) were harvested from wild habitats. Herbs (50%) and leaves (50%) contributed the highest percentage of plant biological forms and parts used in remedy preparation. Conclusion This study recorded plant species with the potential to treat a wide range of illnesses. This is reflected in the high diversity of the recorded species used for medicinal purposes. Pharmacological studies on the plants with high percentage use values and fidelity levels are needed to validate their uses in the management of the said therapeutic applications. Further research on the isolation and characterization of the plant active compounds could lead to the discovery of new potential drugs.


2021 ◽  
Vol 11 (4) ◽  
pp. 2678-2702
Author(s):  
Prabhat Kumar Thella ◽  
V. Ulagamuthalvi

Plants are essential for human life. They help people breathe, provide food, clothing, medicine, and fuel, and also safeguard the environment. Plants can be loaded with medicinal properties and possess active substances that can be used for medical purposes. Several beneficial plant species are disappearing as a result of such factors as global warming, increasing population, professional secrecy, insufficient government support for research efforts, and the lack of public understanding of medicinal plants. It takes time to identify medicinal plants, therefore use professionals to assist you. For better benefit to humankind, a new method to identify and classify therapeutic plants must be developed. Because of the advanced technology in our day and age, medicinal plant identification and classification is an important subject of research in the field of image processing. Feature extraction and classification are the most important components in the process of identifying medicinal plants and classifying them. This research examines methods used in identifying and classifying medicinal plants as well as the medicinal properties of plants that have become increasingly relevant in the recent past. There is a vital importance placed on identifying the suitable medicinal plants in the creation of an ayurvedic medication. In order to identify a medicinal plant, look for these three features: leaf form, colour, and texture. From the both sides of the leaf, there are both deterministic and nondeterministic factors that identify the species. In this study, a combination of traits is designed that is said to identify a single tree the most effectively while minimising errors. The database is made up of scanned photos of both the front and back side of ayurvedic medicinal plant leaves, which is an ayurvedic medicinal plant identification database. In leaf identification, rates as high as 99% have been found when tested on a wide range of classifiers. Extending the prior work by using dried leaves and feature vectors results in identification using which identification rates of 94% are possible. Identification of the correct medicinal plants that goes in to the preparation of a medicine is very important in ayurvedic medicinal industry. The main features required to identify a medicinal plant is its leaf shape, colour and texture. Colour and texture from both sides of the leaf contain deterministic parameters to identify the species. This paper explores feature vectors from both the front and back side of a green leaf along with morphological features to arrive at a unique optimum combination of features that maximizes the identification rate. A database of medicinal plant leaves is created from scanned images of front and back side of leaves of commonly used ayurvedic medicinal plants. The leaves are classified based on the unique feature combination. Identification rates up to 99% have been obtained when tested over a wide spectrum of classifiers. The above work has been extended to include identification by dry leaves and a combination of feature vectors is obtained, using which, identification rates exceeding 94% have been achieved.


2021 ◽  
Author(s):  
samuel chane teferi

Abstract Background Rabies is a zoonotic disease affecting a wide range of wild and domestic animals, including livestocks.It is a major public-health problem which presents huge economic and health burdens in most parts of the developing world. The objective of this review was to prepare a compiled checklist of medicinal plants used traditionally for the management of rabies from various ethnobotanical, ethno pharmacological, and related studies in Ethiopia. Methods A website-based search strategy was employed. Databases (PubMed, Google Scholar, Research Gate, Medline, Scopus, Web of Science) were searched for published studies. The search items used were“medicinal plants”, “traditional medicines”, and “Ethiopia or Indigenous people.” A descriptive statistical method, percentage and frequency were used to analyze ethno-botanical data on reported medicinal plants and associated indigenous knowledge. The results were presented using charts and tables. Results Eighty medicinal plant species which belong to 43 families and 68 genera were found to be used in the treatment of rabies in Ethiopia. Those medicinal plants were distributed in Amhara, Oromia and Southern nation, nationalities and peoples of Ethiopia.Cucurbitaceae and Euphorbiaceae, represented by 7 species (8.75%), Solanaceae represented by 6 (7.5%) species. Phytolacca dodecandra and Justicia schimperianawere the most used/cited plant species. The habit forms of the plant species were herbs 18 (22.5%), shrubs 17 (21.25%) and while the most commonly used parts of the plant were 42% roots and 15% leaf. Conclusions According to the review there are many medicinal plants for the treatment of rabies. It is recommended to perform phytochemical screening for most reported plants.Ethiopia requires an enforceable policy that protects wild medicinal plants and policy incentives for the cultivation of medicinal plants to reduce overexploitation.


2019 ◽  
Vol 35 (6) ◽  
pp. 1782-1788
Author(s):  
Abdulaziz Ali Alomari ◽  
Abdalfatah Abdalla Fadlelmula ◽  
Hassen Harzali

The plant is a huge therapeutic source with enormous applications in curative industry. For new sources of antimicrobial agents, chloroform, ethyl acetate, and n–butanol extracts of two medicinal plants (Dodonaea viscose and Capparis spinosa) were prepared by liquid – liquid extraction. The plants were collected from Shuda mountain / Al-Baha region/ Saudi Arabia and then evaluated systematically. Phytochemical screening tests detect the existence of flavonoids, alkaloids, tannin, terponoids, saponnins and carbohydrates in most of the performed extracts. Antimicrobial activity was assessed against five bacterial and one fungal race. The extracts of the two plants leaves showed wide vision antibacterial activity and significant antifungal activity. The antibacterial activity (zone of inhibition) of Dodonaea viscose species varied from 30 to 18 mm, whereas of Capparis spinosa the range from 20 to 16 mm for ethyl acetate extracts, for n- butanol extracts the inhibition zone differ from 15 – 10 and 16 - 10 mm respectively. These results indicated that antimicrobial activities of plant species differ to a wide range not only between species themselves but also within the tests for antimicrobial evaluation. The current result supports the medicinal use of the leaves of these studied plants which works as an antimicrobial agent. These results compare to other studies carried out for the same plants in different countries in different environments exhibited diverse outcome in chemical constituents in the plant extracts and in their effects on tested types of micro organismswhich may have been due to a number of factors, including geographical location, season and environmental factors, and the method of extraction. This study for the two plant species was first time performed in this area of Saudi Arabia.


Author(s):  
Braja Sundar Barik ◽  
Shritam Das ◽  
Tahziba Hussain

India has a large repository of medicinal plants that are used in traditional medical treatments. Several medicinal plants are useful for treating common ailments and some of the plants include Amla (Emblica cinalis), Ashoka (Saraca asoca), Aswagandha (Withania somnifera), Tulsi (Ocimum sanctum), Sarpa Gandha (Rauwolfia serpentina), Sandalwood (Santalum album), Indian birthwort (Aristolochia indica L.), Brahmi (Bacopa monnieri), Neem (Azardirchata indica), Vringraj (Eclipta alba), Grhit kumara (Aloe vera), Harida (Terminalia chebula) and Madhumalati (Quisqualis indica), Catnip (Nepeta cataria), Cayenne pepper (Capsicum annuum), Sage (Salvia officinalis); etc. Quisquails indica commonly known as the Madhu Malati, is a vine with red flower clusters and is found in abundance in India. It shows a wide range of remarkable medicinal properties. Over the last two decades, large scale research has been conducted to identify bio-active constituents of Quisqualis indica therapeutic prospects. This review summarizes the pharmacognostic properties of Quisqualis indica Linn. Against human pathogenic microorganisms. Several authors have reviewed the medicinal properties of Quisqualis indica Linn.but our review summarizes the anti-bacterial, anti-inflammatory, anti-oxidant, anti-pyretic, anti-helminthic, anti-diarrheal, anti-hyperglycemic, anti-microbial, anti-fungal and immuno-modulatory properties. It would be useful to students, academicians, microbiologists, as it reduces the need for detailed searching. It serves the purpose of quick reference.


Author(s):  
Э. Сэлэнгэ ◽  
Г. Одонтуяа ◽  
Ж. Батхүү Батхүү

Сүүлийн жилүүдэд нийлэг аргаар гарган авсан хүнс болон эмийн бүтээгдэхүүнээс татгалзаж, аль болох байгалийн гаралтай бүтээгдэхүүн хэрэглэх хандлага єсєн нэмэгдэж байгаагийн зэрэгцээ эмийн ургамлын антиоксидант идэвхийн судалгаа ихээхэн сонирхол татсан сэдвийн нэг болоод байна.Бидний судалгааны үр дүнд Монголын ургамлын аймгийн Нийлмэл цэцэгтэн ба Сарнайн овгийн 23 зүйл ургамлын метанолын 51 ханднаас 20 зүйл ургамлын 28 ханд нь чєлєєт радикалыг дарангуйлах сайн идэвхтэй байсан ба ялангуяа ургамлын газрын дээд хэсэг цэцэг, навч, үрийн ханд илүү сайн идэвхтэй байв.Судалгааны дүнд Chamaerhodos erecta-н газрын дээд хэсэг 100µg/ ml концентрацдаа 81.33±0.96 %, Cotoneaster melanocarpa-н иш 100µg/ml концентрацдаа 92.14±0.98 %, Dasiphora fruticosa-н навч, цэцэг, иш 25µg/ml концентрацдаа тус бүр 49.61±4.4 %, 49.98±2.87 %, 57.7±0.84 %, Dasiphora parvifolia-н навч, цэцэг 25µg/ml концентрацдаа 43.22±1.4 %, Filipendula palmatа- н навч, үр 50µg/ml концентрацдаа тус бүр 56.4±0.75 %, 55.41±2.1 %, Rubus sachalinensis-н навч 50µg/ml концентрацдаа 65.22±0.91%-аар чєлєєт радикалыг дарангуйлах онцгой сайн идэвхтэй үр дүнтэй байлаа.Түлхүүр үг: Нийлмэл цэцэгтэн, Сарнайн овог, антиоксидант идэвх, DPPH радикал   Screening of Mongolian Medicinal Plants for their Antioxidant Activity Reactive oxygen species (ROS) and reactive nitrogen species (RNS) are implicated in a wide range of human diseases such as atherosclerosis, certain cancer, inflammation, diabetes, liver injury, Alzheimer, Parkinson and coronary heart pathologies [1, 11]. When an imbalance between ROS/RNS generation and antioxidants occurs, oxidative damage will spread over all the cell targets (DNA, lipids, proteins).Antioxidants in foods and medicinal plants have attracted interest in recent years.The aim of the present study was to search the antioxidant active compounds or a new plant species through the DPPH (1,1-diphenyl-2-picrylhydrazyl) radical scavenging method of the methanol extracts from 23 plant species belonging to 2 botanical families (Compositae, Rosaceae) collected from natural reserves. The antioxidant activity of these plant extracts were compared with standard solution of rutin.From the 51 plant extracts studied, twenty eight gave IC50 values lower than 200µg/ml. The strongest IC50 values were given by the methanol extracts of Chamaerhodos erecta (aerial parts), Dasiphora parvifolia (leaves, flowers), Cotoneaster melanocarpa (stems), Rubus sachalinensis (stems, leaves), Dasiphora fruticosa (flowers, leaves, stems), Cotoneaster melanocarpa (stems), Filipendula palmata (seeds, leaves), Rubus sachalinensis(leaves).Therefore, these plants may have great relevance in the prevention and therapies of diseases in which free radicals are implicated. In further, more detailed studies on the chemical composition of those extracts as well as studies with other models such as in vivo assays will be called for an interest.Acknowledgements We are grateful to prof A.H.Brantner (Laboratory of Pharmacognosy, University of Graz, Austria) for her helpful suggestion. This study was partially supported by Honda foundation, Japan.DOI: http://dx.doi.org/10.5564/pmas.v0i1.58 Proceedings of the Mongolian Academy of Sciences 2010 No.1 pp.48-56


2020 ◽  
Vol 23 (1) ◽  
pp. 10-23
Author(s):  
Fatemeh Ebrahimi ◽  
Mohammadali Torbati ◽  
Javad Mahmoudi ◽  
Hadi Valizadeh

Purpose: Medicinal plants with a variety of phytochemical ingredients remain a potential source for new drug discovery. The use of medicinal herbs in a wide range of diseases and symptoms, such as bleeding, is prevalent in traditional and ethno medicine worldwide. Thus, this work provides a comprehensive review of medicinal plants or their isolated compounds, with respect to their ethno-medicinal use, which have demonstrated the stimulating effect on the hemostasis process. Methods: The relevant studies were withdrawn from electronic databases including Pubmed, EMBASE and Web of Science with a structured search methodology. Results: The total of 17 medicinal plants with hemostatic activity were extracted. The most frequently studied plant families were Compositae, Lamiaceae, Fabaceae, and Asteraceae. Bioactive compounds exerting hemostatic activity included tannins, iridoid glycosides, glycoconjugate, lignan, saponins and phenolic compounds. The most attributed mechanisms include coagulation stimulation via increasing the factor XII activity and plasma fibrinogen levels, the fibrinolysis inhibition, vascular or smooth muscle constriction and platelet aggregation. The most important adverse effects of high dose extract or isolated compounds administration were hepatotoxicity and nephrotoxicity. Conclusion: This review provides a list of medicinal plants with hemostatic activity that could be used as valuable sources of new plant-based hemostatic agents. Furthermore, this could be practical in detecting possible interactions of plants with anticoagulant, antiplatelet, fibrinolytic and antifibrinolytic medications.


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