Comprehensive evaluation of the quality of Platycodi Radix with reference standard extract

Planta Medica ◽  
2015 ◽  
Vol 81 (16) ◽  
Author(s):  
L Zeng ◽  
H Kong ◽  
M Zhu ◽  
W Yan
Keyword(s):  
Comprehensive Evaluation ◽  
Reference Standard ◽  
Platycodi Radix

Combinative method using multi-components quantitation by single reference standard and HPLC fingerprint for comprehensive evaluation of Rhodiola crenulata H.Ohba

2014 ◽  
Vol 6 (15) ◽  
pp. 5891-5898 ◽  
Author(s):  
Yiyang Du ◽  
Qing Li ◽  
Jingjing Liu ◽  
Yidi Yin ◽  
Kaishun Bi
Keyword(s):  
Quantitative Analysis ◽  
Comprehensive Evaluation ◽  
Reference Standard ◽  
Fingerprint Analysis ◽  
Chromatographic Fingerprint ◽  
Hplc Fingerprint ◽  
Rhodiola Crenulata ◽  
Different Origins

HPLC-DAD quantitative analysis and chromatographic fingerprint analysis were developed to evaluate the quality of Rhodiola crenulata H.Ohba from different origins.

scholarly journals Comprehensive Evaluation of PAXgene Fixation on Oral Cancer Tissues Using Routine Histology, Immunohistochemistry, and FTIR Microspectroscopy

Biomolecules ◽  
2021 ◽  
Vol 11 (6) ◽  
pp. 889
Author(s):  
Pooja Lahiri ◽  
Suranjana Mukherjee ◽  
Biswajoy Ghosh ◽  
Debnath Das ◽  
Basudev Lahiri ◽  
...  
Keyword(s):  
Comprehensive Evaluation ◽  
Antigen Retrieval ◽  
Tissue Fixation ◽  
Ftir Microspectroscopy ◽  
Protein Secondary Structures ◽  
Associated Proteins ◽  
Cancer Tissues ◽  
Formalin Fixed ◽  
Fixation System

The choice of tissue fixation is critical for preserving the morphology and biochemical information of tissues. Fragile oral tissues with lower tensile strength are challenging to process for histological applications as they are prone to processing damage, such as tissue tear, wrinkling, and tissue fall-off from slides. This leads to loss of morphological information and unnecessary delay in experimentation. In this study, we have characterized the new PAXgene tissue fixation system on oral buccal mucosal tissue of cancerous and normal pathology for routine histological and immunohistochemical applications. We aimed to minimize the processing damage of tissues and improve the quality of histological experiments. We also examined the preservation of biomolecules by PAXgene fixation using FTIR microspectroscopy. Our results demonstrate that the PAXgene-fixed tissues showed significantly less tissue fall-off from slides. Hematoxylin and Eosin staining showed comparable morphology between formalin-fixed and PAXgene-fixed tissues. Good quality and slightly superior immunostaining for cancer-associated proteins p53 and CK5/6 were observed in PAXgene-fixed tissues without antigen retrieval than formalin-fixed tissues. Further, FTIR measurements revealed superior preservation of glycogen, fatty acids, and amide III protein secondary structures in PAXgene-fixed tissues. Overall, we present the first comprehensive evaluation of the PAXgene tissue fixation system in oral tissues. This study concludes that the PAXgene tissue fixation system can be applied to oral tissues to perform diagnostic molecular pathology experiments without compromising the quality of the morphology or biochemistry of biomolecules.

scholarly journals Popularity and performance of bioinformatics software: the case of gene set analysis

2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Chengshu Xie ◽  
Shaurya Jauhari ◽  
Antonio Mora
Keyword(s):  
Comprehensive Evaluation ◽  
Gene Set Analysis ◽  
Tool Selection ◽  
Functional Interpretation ◽  
Selection Procedures ◽  
Gene Set ◽  
And Performance ◽  
Reported Data ◽  
Performance Results

Abstract Background Gene Set Analysis (GSA) is arguably the method of choice for the functional interpretation of omics results. The following paper explores the popularity and the performance of all the GSA methodologies and software published during the 20 years since its inception. "Popularity" is estimated according to each paper's citation counts, while "performance" is based on a comprehensive evaluation of the validation strategies used by papers in the field, as well as the consolidated results from the existing benchmark studies. Results Regarding popularity, data is collected into an online open database ("GSARefDB") which allows browsing bibliographic and method-descriptive information from 503 GSA paper references; regarding performance, we introduce a repository of jupyter workflows and shiny apps for automated benchmarking of GSA methods (“GSA-BenchmarKING”). After comparing popularity versus performance, results show discrepancies between the most popular and the best performing GSA methods. Conclusions The above-mentioned results call our attention towards the nature of the tool selection procedures followed by researchers and raise doubts regarding the quality of the functional interpretation of biological datasets in current biomedical studies. Suggestions for the future of the functional interpretation field are made, including strategies for education and discussion of GSA tools, better validation and benchmarking practices, reproducibility, and functional re-analysis of previously reported data.

A STUDY ON IMPLEMENTATION OF CONTINUOUS AND COMPREHENSIVE EVALUATION IN UPPER PRIMARY SCHOOLS OF KERALA

2016 ◽  
pp. 168-176
Author(s):  
R.G Kothari ◽  
Mary Vineetha Thomas
Keyword(s):  
Primary Schools ◽  
Comprehensive Evaluation ◽  
Secondary Level ◽  
The State ◽  
Quality Of Education ◽  
Government Schools ◽  
Curriculum Framework ◽  
Powerful Means ◽  
Made In

Evaluation is widely acknowledged as a powerful means of improving the quality of education. The introduction of Continuous and Comprehensive Evaluation (CCE) is considered as one of the major steps taken in this regard to improve and strengthen the quality of learner evaluation. The state of Kerala has been going through a series of educational reforms over the last decade or so and the introduction of CCE in the state is one among them. As emphasized by Kerala Curriculum Framework (2007) the implementation of new evaluation practices focusing on CCE was introduced right from primary to secondary level. Though the state has made all-out efforts to implement CCE in its true spirit, the questions that remain unanswered are that whether CCE has been actually and effectively implemented in all classes, what problems are being faced by teachers while implementing CCE. The present paper is a brief attempt made in this regard and is directed towards answering these questions and giving suggestions for the same. The study has been conducted on teachers of upper primary government schools of Kerala.

A Method of the Comprehensive Evaluation of Surface Integrity in Micro- and Nano-Machining

2007 ◽  
Author(s):  
Guicheng Wang ◽  
Chunyan Zhang ◽  
Hongjie Pei ◽  
Yunming Zhu ◽  
Chungen Shen ◽  
...  
Keyword(s):  
Surface Integrity ◽  
Evaluation System ◽  
Metal Cutting ◽  
Comprehensive Evaluation ◽  
Rapid Development ◽  
Analytic Hierarchy ◽  
Ultra Precision ◽  
Edge Quality ◽  
Hierarchy Process

The surface quality is always the crucial element of machined quality in precision ultra-precision metal cutting. A new concept that the surface integrity should include the edge quality of parts is put forward In this paper, the weight value of a series of characteristic parameters of surface integrity are calculated with using analytic hierarchy process, three basic methods of evaluating surface integrity are presented, and the comprehensive evaluation system has been formed which will theoretically play a great important role on rapid development in the precision machining.

scholarly journals DEVELOPMENT OF CRITERIA FOR EVALUATING THE QUALITY OF TRAINING FOR OFFICIALS OF THE INTERNAL AFFAIRS AGENCIES OF THE RUSSIAN FEDERATION AS CANDIDATES FOR PARTICIPATION IN PEACEKEEPING MISSIONS

2021 ◽  
Vol 5 (11(75)) ◽  
pp. 09-16
Author(s):  
E. Baeva ◽  
M. Burkova ◽  
E. Davidova
Keyword(s):  
Russian Federation ◽  
Current Problem ◽  
Professional Competence ◽  
Comprehensive Evaluation ◽  
Objective Assessment ◽  
Educational Process ◽  
The Russian Federation ◽  
Internal Affairs ◽  
Peacekeeping Missions

The objective of this exercise is to resolve the existing contradiction between the need for an objective assessment of the quality of training of IAO candidates for peacekeeping missions, based on specific training objectives, and the existing system for obtaining specific results of educational activities by means of a quantitative method for evaluating knowledge, skills and skills (pedagogical testing). This article deals with the current problem of assessing the quality of the educational process at the All-Russian Institute for Advanced Training of Staff of the Ministry of Internal Affairs of the Russian Federation when preparing candidates for participation in United Nations peacekeeping missions. The scientific novelty of the work consists in presenting private criteria for the formation of professional competence of the international UN police (motivational, communicative-activity, cognitive and personal-result) and indicators to each of these criteria. As a result, a system of objective and comprehensive evaluation of the educational process has been developed.

scholarly journals Research on Liquor Storage Based on Statistical Analysis Model

2021 ◽  
Vol 5 (3) ◽  
Author(s):  
Xuhua Xu
Keyword(s):  
Index System ◽  
Comprehensive Evaluation ◽  
Principal Component ◽  
Evaluation Index System ◽  
Classification Model ◽  
Analysis Model ◽  
The Index System ◽  
Storage Methods ◽  
Physical And Chemical

According to the physical and chemical indexes of different periods, different storage containers and different storage sites, a two overall T test was used to show that there were significant differences in physical and chemical indexes of liquor body in different detection sites. Correlation analysis of wine storage in different storage methods by Spearman correlation coefficient. By using the principal component analysis method, the comprehensive evaluation index system of the quality of the wine body was constructed, and the classification model of the detection location based on the comprehensive evaluation was established by using the index system. The detection sites were classified, and the results showed that the detection sites were divided into four grades.

scholarly journals A study of the sensitivity and specificity of the Magnetic Resonance Imaging (MRI) technique used in the diagnosis of endometriosis versus the intraoperative appearance considered the reference standard in the diagnosis of endometriosis

2021 ◽  
Vol 28 (1) ◽  
pp. 55-61
Author(s):  
Alexandra RADU ◽  
◽  
Elvira BRATILA ◽  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Sensitivity And Specificity ◽  
Reference Standard ◽  
Resonance Imaging ◽  
First Line ◽  
Magnetic Resonance Imaging Mri ◽  
Asymptomatic Women ◽  
Bladder Invasion

Endometriosis is a gynecological pathology with chronic symptoms, which negatively affects the patient’s quality of life. The prevalence of endometriosis in asymptomatic women is between 2% and 50%, depending on the populations studied and the method of diagnosis. The severity of the symptoms as well as the probability of diagnosing endometriosis increases with age9. Because endometriosis is a gynecological condition with a nonspecific clinical picture, sometimes even asymptomatic, imaging technology can be considered the first line of diagnosis for this pathology. The main objective of this study is to evaluate the sensitivity and specificity of nuclear magnetic resonance imaging (MRI) used in the diagnosis of endometriotic lesions depending on their location, and compare the results obtained with the intraoperative appearance considered a reference standard in the diagnosis of endometriosis. Our study revealed the highest specificity for MRI in the case of endometriotic bladder invasion, respectively the highest sensitivity for endometriotic rectal nodules.

Sign in / Sign up

Export Citation Format

Share Document