scholarly journals Increasing viscosity of the intestinal contents alters small intestinal structure and intestinal growth, and stimulates proliferation of enterotoxigenicEscherichia coliin newly-weaned pigs

2001 ◽  
Vol 86 (4) ◽  
pp. 487-498 ◽  
Author(s):  
D. E. McDonald ◽  
D. W. Pethick ◽  
B. P. Mullan ◽  
D. J. Hampson
Keyword(s):  
Body Weight Gain ◽  
High Viscosity ◽  
Intestinal Morphology ◽  
Whole Body ◽  
Soluble Fibre ◽  
Low Viscosity ◽  
Accelerate Development ◽  
Small Intestinal ◽  
Digesta Viscosity ◽  
Small Intestinal Villus

Sources of viscous soluble fibre, such as barley and oats, have often been included in the weaning diet of the pig to accelerate development of the large intestine. Inclusion of a non-fermentable, viscous compound, sodium carboxymethylcellulose (CMC), in a low-fibre weaning diet was tested to assess the influence of digesta viscosity on the gut in the absence of increased fermentation. Two CMC sources, of low and high viscosity, were added to cooked rice-based diet at 40 g/kg total diet. A third control rice diet did not contain any CMC. Diets were fed for 13 d following weaning at 3 weeks of age. Addition of CMC to the diet significantly increased the intestinal viscosity of digesta within the small (P<0·001) and large (P<0·05) intestine. No simple association was found between increases in intestinal viscosity and effects on intestinal morphology and whole-body growth. The average empty-body-weight gain and the small intestinal villus height increased with low-viscosity CMC, but decreased with the high-viscosity CMC group. The full large intestinal weight increased in all pigs fed CMC. Dietary CMC (both low- and high-viscosity) increased the percentage moisture of digesta and faeces, and was associated with increased faecal shedding of enterotoxigenic haemolyticEscherichia coli. Feed ingredients in weaning diets that excessively increase the viscosity of the intestinal digesta may be detrimental to pig health and production.

scholarly journals Liver nitrogen movements during short-term infusion of high levels of ammonia into the mesenteric vein of sheep

2001 ◽  
Vol 86 (4) ◽  
pp. 507-513 ◽  
Author(s):  
G. D. Milano ◽  
G. E. Lobley
Keyword(s):  
Body Weight Gain ◽  
High Viscosity ◽  
Intestinal Morphology ◽  
Whole Body ◽  
Soluble Fibre ◽  
Low Viscosity ◽  
Accelerate Development ◽  
Digesta Viscosity ◽  
Small Intestinal Villus ◽  
Pig Health

Sources of viscous soluble fibre, such as barley and oats, have often been included in the weaning diet of the pig to accelerate development of the large intestine. Inclusion of a non-fermentable, viscous compound, sodium carboxymethylcellulose (CMC), in a low-fibre weaning diet was tested to assess the influence of digesta viscosity on the gut in the absence of increased fermentation. Two CMC sources, of low and high viscosity, were added to cooked rice-based diet at 40 g/kg total diet. A third control rice diet did not contain any CMC. Diets were fed for 13 d following weaning at 3 weeks of age. Addition of CMC to the diet significantly increased the intestinal viscosity of digesta within the small (P<0·001) and large (P<0·05) intestine. No simple association was found between increases in intestinal viscosity and effects on intestinal morphology and whole-body growth. The average empty-body-weight gain and the small intestinal villus height increased with low-viscosity CMC, but decreased with the high-viscosity CMC group. The full large intestinal weight increased in all pigs fed CMC. Dietary CMC (both low- and high-viscosity) increased the percentage moisture of digesta and faeces, and was associated with increased faecal shedding of enterotoxigenic haemolytic Escherichia coli. Feed ingredients in weaning diets that excessively increase the viscosity of the intestinal digesta may be detrimental to pig health and production.

scholarly journals Exogenous dietary xylanase ameliorates viscosity-induced anti-nutritional effects in wheat-based diets for White Pekin ducks (Anas platyrinchos domesticus)

2004 ◽  
Vol 92 (1) ◽  
pp. 87-94 ◽  
Author(s):  
Olayiwola Adeola ◽  
Michael R. Bedford
Keyword(s):  
Weight Gain ◽  
High Viscosity ◽  
Diet Group ◽  
Pekin Ducks ◽  
Low Viscosity ◽  
Nutritional Effect ◽  
Nutrient Utilisation ◽  
Metabolisable Energy ◽  
Nutritional Effects ◽  
Digesta Viscosity

Nutrient utilisation and growth performance responses of White Pekin ducks (Anas platyrinchos domesticus) offered diets containing low- or high-viscosity wheat supplemented with xylanase were investigated in two studies. In Expt 1, six diets consisting of low-viscosity wheat or high-viscosity wheat supplemented with 0·0, 1·5 or 3·0 g xylanase (2590 units/g)/kg diet were used in a true metabolisable energy (TME) bioassay with eight 8-week-old ducks per diet group. In Expt 2, eight pens of ten 3-d-old ducks per pen for each of six wheat-based diets arranged in a 2×3 factorial of low-viscosity or high-viscosity wheat and 0·0, 1·5 or 3·0 g xylanase/kg were used in a 42 d growth study. High-viscosity wheat depressed (P>0·001) TME and xylanase supplementation improved (P>0·001) TME, more so for high-viscosity than low-viscosity wheat. Xylanase supplementation of the high-viscosity wheat-based diet improved (P>0·05) weight gain and gain:feed ratio by 13 and 12% respectively. There was no weight gain or gain:feed ratio response to xylanase supplementation of the low-viscosity wheat-based diet. Xylanase supplementation reduced (P>0·001) the viscosity of duodenal and ileal digesta for high-viscosity but not low-viscosity wheat-based diets. Ileal digestibilities of nutrients and energy were higher (P>0·001) for low-viscosity than high-viscosity wheat-based diets; xylanase supplementation improved (P>0·05) energy, fat, N and starch digestibilities. Given that xylanase supplementation of high-viscosity wheat assuaged its anti-nutritional effect, it is surmised that digesta viscosity plays a role in anti-nutritional effects in wheat-based diets for ducks.

scholarly journals A Novel Modified Hydrated Sodium Calcium Aluminosilicate (HSCAS) Adsorbent Can Effectively Reduce T-2 Toxin-Induced Toxicity in Growth Performance, Nutrient Digestibility, Serum Biochemistry, and Small Intestinal Morphology in Chicks

Toxins ◽  
2019 ◽  
Vol 11 (4) ◽  
pp. 199 ◽  
Author(s):  
Jin-Tao Wei ◽  
Kun-Tan Wu ◽  
Hua Sun ◽  
Mahmoud Mohamed Khalil ◽  
Jie-Fan Dai ◽  
...  
Keyword(s):  
Growth Performance ◽  
Body Weight Gain ◽  
Dietary Supplementation ◽  
Serum Biochemistry ◽  
Nutrient Digestibility ◽  
Intestinal Morphology ◽  
Control Group ◽  
Sodium Calcium ◽  
Calcium Aluminosilicate ◽  
Small Intestinal

The objective of this study was to evaluate the ability of a modified hydrated sodium calcium aluminosilicate (HSCAS) adsorbent to reduce the toxicity of T-2 toxin in broilers. Ninety-six one-day-old male broilers were randomly allocated into four experimental groups with four replicates of six birds each. The four groups, 1–4, received a basal diet (BD), a BD plus 6.0 mg/kg T-2 toxin, a BD plus 6.0 mg/kg T-2 toxin with 0.05% modified HSCAS adsorbent, and a BD plus 0.05% modified HSCAS adsorbent, respectively, for two weeks. Growth performance, nutrient digestibility, serum biochemistry, and small intestinal histopathology were analyzed. Compared to the control group, dietary supplementation of T-2 toxin decreased (p < 0.05) body weight gain, feed intake, and the feed conversion ratio by 11.4%–31.8% during the whole experiment. It also decreased (p < 0.05) the apparent metabolic rates of crude protein, calcium, and total phosphorus by 14.9%–16.1%. The alterations induced by T-2 toxin were mitigated (p < 0.05) by the supplementation of the modified HSCAS adsorbent. Meanwhile, dietary modified HSCAS adsorbent supplementation prevented (p < 0.05) increased serum aspartate aminotransferase by T-2 toxin at d 14. It also prevented (p < 0.05) T-2 toxin-induced morphological changes and damage in the duodenum, jejunum, and ileum of broilers. However, dietary supplementation of the modified HSCAS adsorbent alone did not affect (p > 0.05) any of these variables. In conclusion, these findings indicate that the modified HSCAS adsorbent could be used against T-2 toxin-induced toxicity in growth performance, nutrient digestibility, and hepatic and small intestinal injuries in chicks.

scholarly journals Effect of probiotic and fisetin supplementation on performance, carcass characteristics and small intestinal morphology in broiler chickens

2021 ◽  
Vol 2 (1) ◽  
pp. 23-32
Author(s):  
Victory Osirimade Sumanu ◽  
Tagang Aluwong ◽  
Joseph Olusegun Ayo ◽  
Ngozi Ejum Ogbuagu
Keyword(s):  
Feed Intake ◽  
Broiler Chickens ◽  
Body Weight Gain ◽  
Carcass Characteristics ◽  
Intestinal Morphology ◽  
Control Group ◽  
Group Iii ◽  
Treatment Groups ◽  
Group I ◽  
Small Intestinal

Abstract We studied the dietary effects of probiotic and fisetin supplementation on performance parameters, carcass characteristics and small intestinal morphology in broiler chickens. Sixty (one-day-old) Arbo Acre breed of broiler chickens were allotted into 4 groups of 15 each randomly: Group I, Control was administered only distilled water; Group II, fisetin (5 mg/kg); Group III, probiotic (4.125×106 cfu/100 mL); and Group IV, probiotic and fisetin (4.125×106 cfu/100 mL and 5 mg/kg, respectively) for the first one week of life. All administrations were performed orally through gavage. Broiler chickens supplemented with probiotic and probiotic+fisetin had greater feed intake significantly (P<0.05) at weeks 5 and 6, when compared respectively with those of the control and fisetin groups which had lesser feed intake values. Body weight gain was of great significance (P<0.05) in the probiotic-supplemented broiler chickens, while that of the control was less. Carcass quality of the probiotic-supplemented group was higher in significance (P<0.05) than any other treatment group which had lower qualities. The pH changes in the breast muscle was lesser significantly (P<0.05) in the probiotic+fisetin group, when compared with those of the control group which had greater changes. The villus height/crypt height ratio was higher in significance (P<0.05) in the treatment groups, while that of the control group was lower. In conclusion, dietary supplementation of probiotic may enhance broiler chickens’ productivity, by improving performance, carcass weight, pH, and small intestinal morphology as compared to fisetin supplementation.

scholarly journals Growth performance and small intestinal morphology of native chickens after feed supplementation with tryptophan and threonine during the starter phase

2020 ◽  
Vol 13 (12) ◽  
pp. 2765-2771
Author(s):  
Charles V. Lisnahan ◽  
Oktovianus R. Nahak
Keyword(s):  
Growth Performance ◽  
Body Weight Gain ◽  
Amino Acid Content ◽  
Intestinal Morphology ◽  
The Other ◽  
Feed Conversion ◽  
Treatment Groups ◽  
Randomized Design ◽  
Small Intestinal ◽  
Native Chickens

Background and Aim: The amino acid content of feed can affect growth performance of poultry during the first 6 weeks of life or the starter phase. Unlike for broiler and layer chickens, there is no information concerning standard requirements for tryptophan and threonine during the starter phase. This study aimed to determine the amount of threonine and tryptophan that should be supplemented in chicken feed to maximize growth performance and small intestinal morphology of native chickens during the starter phase. Materials and Methods: A total of 128 day-old native chickens were divided into four treatment groups with four replications based on a completely randomized design. The treatment diets were as follows: T0 (control feed); T1 (T0+0.10% L-tryptophan+0.35% L-threonine); T2 (T0+0.17% L-tryptophan+0.68% L-threonine); and T3 (T0+0.25% L-tryptophan+1.00% L-threonine). Results: The feed intake was highest for the T2 and T3 groups (123.06 and 124.18 g/bird/week, respectively). The T3 group had the highest body weight gain (49.35 g/bird/week) and carcass weight (201.44 g/bird) relative to the other groups, while the T2 and T3 groups showed similar, significant (p<0.05) increases in feed conversion ratio (2.57 and 2.51, respectively) and carcass percentage (60.88 and 60.99%/bird, respectively) compared to the other groups. This study showed villi height, crypt depth, and villi width of duodenum, the highest jejunum and ileum of T3 (1109.00±27.26, 1325.50±75.00, 1229.50±101.68, 225.50±17.52, 236.00±24.81, 219.75±17.25, 192.25±14.41, 191.75±4.79, and 184.75±6.40, respectively) compare to other treatment. Conclusion: These results indicate that supplementation of feed with 0.17% L-tryptophan and 0.68% L-threonine positively affected the growth performance and small intestinal morphology of native chickens during the starter phase.

scholarly journals A Low-Viscosity BisGMA Derivative for Resin Composites: Synthesis, Characterization, and Evaluation of Its Rheological Properties

Materials ◽  
2021 ◽  
Vol 14 (2) ◽  
pp. 338
Author(s):  
Ali Alrahlah ◽  
Abdel-Basit Al-Odayni ◽  
Haifa Fahad Al-Mutairi ◽  
Bashaer Mousa Almousa ◽  
Faisal S. Alsubaie ◽  
...  
Keyword(s):  
Substantial Reduction ◽  
Triethylene Glycol ◽  
High Viscosity ◽  
Resin Matrix ◽  
Resonance Spectroscopy ◽  
Dental Resin ◽  
Triethylene Glycol Dimethacrylate ◽  
Oh Groups ◽  
Low Viscosity ◽  
13C Nuclear Magnetic Resonance

This study aimed to synthesize new bisphenol A-glycidyl methacrylate (BisGMA) derivatives, targeting a reduction in its viscosity by substituting one of its OH groups, the leading cause of its high viscosity, with a chlorine atom. Hence, this monochloro-BisGMA (mCl-BisGMA) monomer was synthesized by Appel reaction procedure, and its structure was confirmed using Fourier transform infrared spectroscopy, 1H and 13C-nuclear magnetic resonance spectroscopy, and mass spectroscopy. The viscosity of mCl-BisGMA (8.3 Pa·s) was measured under rheometry conditions, and it was found to be more than 65-fold lower than that of BisGMA (566.1 Pa·s) at 25 °C. For the assessment of the viscosity changes of model resins in the presence of mCl-BisGMA, a series of resin matrices, in which, besides BisGMA, 50 wt % was triethylene glycol dimethacrylate, were prepared and evaluated at 20, 25, and 35 °C. Thus, BisGMA was incrementally replaced by 25% mCl-BisGMA to obtain TBC0, TBC25, TBC50, TBC75, and TBC100 blends. The viscosity decreased with temperature, and the mCl-BisGMA content in the resin mixture increased. The substantial reduction in the viscosity value of mCl-BisGMA compared with that of BisGMA may imply its potential use as a dental resin matrix, either alone or in combination with traditional monomers. However, the various properties of mCl-BisGMA-containing matrices should be evaluated.

scholarly journals A Conceptional Approach of Resin-Transfer-Molding to Rosin-Sourced Epoxy Matrix Green Composites

Aerospace ◽  
2020 ◽  
Vol 8 (1) ◽  
pp. 5
Author(s):  
Sicong Yu ◽  
Xufeng Zhang ◽  
Xiaoling Liu ◽  
Chris Rudd ◽  
Xiaosu Yi
Keyword(s):  
Composite Laminates ◽  
Resin Transfer Molding ◽  
High Viscosity ◽  
Ramie Fiber ◽  
Liquid Composite Molding ◽  
Curing Agent ◽  
Molding Process ◽  
Transfer Molding ◽  
Low Viscosity ◽  
Composite Molding

In this concept-proof study, a preform-based RTM (Resin Transfer Molding) process is presented that is characterized by first pre-loading the solid curing agent onto the preform, and then injecting the liquid nonreactive resin with an intrinsically low viscosity into the mold to infiltrate and wet the pre-loaded preform. The separation of resin and hardener helped to process inherently high viscosity resins in a convenient way. Rosin-sourced, anhydrite-cured epoxies that would normally be regarded as unsuited to liquid composite molding, were thus processed. Rheological tests revealed that by separating the anhydrite curing agent from a formulated RTM resin system, the remaining epoxy liquid had its flowtime extended. C-scan and glass transition temperature tests showed that the preform pre-loaded with anhydrite was fully infiltrated and wetted by the liquid epoxy, and the two components were diffused and dissolved with each other, and finally, well reacted and cured. Composite laminates made via this approach exhibited roughly comparable quality and mechanical properties with prepreg controls via autoclave or compression molding, respectively. These findings were verified for both carbon and ramie fiber composites.

scholarly journals Magnesium Deficiency Alters Expression of Genes Critical for Muscle Magnesium Homeostasis and Physiology in Mice

Nutrients ◽  
2021 ◽  
Vol 13 (7) ◽  
pp. 2169
Author(s):  
Dominique Bayle ◽  
Cécile Coudy-Gandilhon ◽  
Marine Gueugneau ◽  
Sara Castiglioni ◽  
Monica Zocchi ◽  
...  
Keyword(s):  
Gastrocnemius Muscle ◽  
Magnesium Deficiency ◽  
Mitochondrial Dynamics ◽  
Body Weight Gain ◽  
Whole Body ◽  
Muscle Physiology ◽  
Deficient Diet ◽  
Muscle Weight ◽  
Magnesium Homeostasis ◽  
Expression Of Genes

Chronic Mg2+ deficiency is the underlying cause of a broad range of health dysfunctions. As 25% of body Mg2+ is located in the skeletal muscle, Mg2+ transport and homeostasis systems (MgTHs) in the muscle are critical for whole-body Mg2+ homeostasis. In the present study, we assessed whether Mg2+ deficiency alters muscle fiber characteristics and major pathways regulating muscle physiology. C57BL/6J mice received either a control, mildly, or severely Mg2+-deficient diet (0.1%; 0.01%; and 0.003% Mg2+ wt/wt, respectively) for 14 days. Mg2+ deficiency slightly decreased body weight gain and muscle Mg2+ concentrations but was not associated with detectable variations in gastrocnemius muscle weight, fiber morphometry, and capillarization. Nonetheless, muscles exhibited decreased expression of several MgTHs (MagT1, CNNM2, CNNM4, and TRPM6). Moreover, TaqMan low-density array (TLDA) analyses further revealed that, before the emergence of major muscle dysfunctions, even a mild Mg2+ deficiency was sufficient to alter the expression of genes critical for muscle physiology, including energy metabolism, muscle regeneration, proteostasis, mitochondrial dynamics, and excitation–contraction coupling.

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