Lipid-soluble antioxidants status and some of its socio-economic determinants among pregnant Ethiopians at the third trimester

2005 ◽  
Vol 8 (6) ◽  
pp. 582-587 ◽  
Author(s):  
Yared Wondmikun

AbstractObjectiveTo determine the serum levels of three lipid-soluble antioxidants (retinol, β-carotene and α-tocopherol) in pregnant women attending an antenatal clinic (ANC) in Gondar, Ethiopia.DesignA cross-sectional study involving laboratory determination of serum levels of retinol, α-tocopherol and β-carotene using high-performance liquid chromatography and questionnaire-based assessment of socio-economic status.SettingANC of a university teaching hospital.SubjectsThree hundred and twenty-two healthy pregnant women in their third trimester, who attended the ANC.ResultsMean serum levels of retinol, α-tocopherol and β-carotene were found to be 1.23±0.5, 25.5±0.9 and 0.21±0.09 μmol l−1, respectively. The prevalence of vitamin A deficiency (<1.05 μmol l−1) among pregnant women was 38.5%. Women having low retinol (vitamin A) levels were highly likely to live in earth-floored and mud-walled houses, and less likely to own a house and to have a latrine.ConclusionThe study shows that serum levels of lipid-soluble antioxidants were low among ANC attendees in northern Ethiopia. It also indicates that some socio-economic factors (such as poor housing standard) are associated with vitamin A deficiency.

2004 ◽  
Vol 47 (3) ◽  
pp. 189-193 ◽  
Author(s):  
Iclal Meram ◽  
Ali Ihsan Bozkurt ◽  
Sahin Kılıncer ◽  
Birgül Ozcirpici ◽  
Servet Ozgur

Vitamin A levels during pregnancy have important influences on the health of pregnant women and the growing fetus. Therefore, plasma vitamin A and β-carotene concentrations during pregnancy in Turkish women living in Gaziantep city were investigated in a prevalence study. Optimum sample size was determined as 252 for vitamin A deficiency and vitamin A and β-carotene levels were examined in 427 pregnant women aged 14–44 years. Vitamin A and β-carotene concentrations were measured spectrophotometrically by Neeld Pearson method. Vitamin A and β-carotene concentrations in pregnant women were found as 1.14 ± 0.44 μmol/L, and 1.80 ± 0.66 μmol/L, respectively. Plasma vitamin A concentrations were found in low levels (<1.05 μmol/L) in 45.5 % of pregnant women. Vitamin A deficiency (<0.7 μmol/L) was determined in 16.9% of pregnant women. A mild negative correlation was obtained between the vitamin A concentration and pregnancy period. Vitamin A levels of pregnant women were decreased significantly in the third trimester (p<0.05). The findings of present study suggest that vitamin A levels of pregnant women were poor in the region. Therefore, the intake of vitamin A with foods should be improved. Supplementation of vitamin A might benefit at improving maternal and child health especially in high-risk groups especially in developing countries. Monitoring vitamin A levels in pregnant women is very important for also determining low and high levels.


2020 ◽  
Vol 19 (1) ◽  
pp. 13-18
Author(s):  
Amit Timilsina ◽  
Rajan Paudel ◽  
Anisha Shrestha

Background: Pregnancy demands adequate nutritional requirements for foetal growth, good health of pregnant women and to avoid adverse effects during pregnancy. Women from developing countries with limited resources have inadequate consumption of nutritional diets. This paper assesses the nutrient intake and dietary pattern of Nepalese pregnant women compared with recommended nutrient intake. This paper also observes trimester wise nutrient intake among pregnant women in Nepal.Methodology: A descriptive cross-sectional study was conducted among 323 pregnant women who visited Gynaecology and Obstetrics Out-Patient Department (OPD) at Tribhuvan University Teaching Hospital (TUTH) for regular Antenatal Care (ANC) check-ups. Systematic random sampling methods were followed and data were collected from September 2016 to October 2016. Nutrient intake was evaluated with a 24-hour dietary recall method and compared with the Nepalese Food Composition Table 2017 for available nutrients. Face-to-face structured interviews were conducted to assess the nutrient intake of the respondents. The data were entered in Microsoft Excel 2007 and statistical analysis was carried out in SPSS v26. The descriptive analysis was done to identify the distribution of socio-demographic variables of pregnant women. The one-way Analysis of Variance (ANOVA) was used to compare the mean of nutrient intake distribution while Tukey’s post-hoc test was done to compare trimester-wise nutrient intakes.Results: Except for fat, the intake of nutrients were below the Nepalese Recommended Nutrient Intake. Carbohydrate and energy intake in the second and third trimester was significantly different from that in the first trimester (p = 0.006 and 0.004 respectively for carbohydrates and p = 0.009 and 0.002 respectively for energy intake). However, riboflavin intake was significantly lower only in the third trimester as compared to the first (p = 0.025) while there were no significant intake differences between the first and second trimester and second and third trimester. No significant trimester wise differences were observed for intake distribution of other nutrients. Cereal intake was found to be abundant in the diet of pregnant women followed by pulses, legumes, and other vegetables.Conclusion: The research concludes inadequate nutrient intake among pregnant women as compared to the national Recommended Nutrient Intake.  


2019 ◽  
Vol 47 (2) ◽  
pp. 183-189 ◽  
Author(s):  
Diana Garretto ◽  
Youn-Kyung Kim ◽  
Loredana Quadro ◽  
Rebekah R. Rhodas ◽  
Veronica Pimentel ◽  
...  

Abstract Background As breastfeeding awareness and social acceptance are increased, maternal nutritional deficiency requires more investigation. Methods A prospective cohort study was conducted to determine if vitamin A deficiency is more common in pregnant, lactating post-bariatric surgery women in an inner city population. Antepartum, women after bariatric surgery and controls with no history of malabsorption were recruited. Third trimester, postpartum maternal blood and cord blood were collected as well as three breast milk samples: colostrum, transitional and mature milk. A nutritional survey of diet was completed. Each serum sample was analyzed for total retinol and β-carotene; breast milk samples were analyzed for retinol and retinyl esters, total retinol and β-carotene. Results Fifty-three women after bariatric surgery and 66 controls were recruited. Postpartum serum retinol was significantly higher in women after bariatric surgery in the univariate analysis (P<0.0001) and confirmed in the multiple linear mixed model (P=0.0001). Breast milk colostrum retinol and transitional milk total retinol were significantly greater in the bariatric surgery group in the univariate analysis (P=0.03 and P=0.02, respectively), but not after adjusting for confounders. Serum β-carotene in the third trimester and postpartum were lower (P<0.0001 and P=0.003, respectively) in the bariatric surgery group but not after adjusting for confounders. Vitamin A deficiency was high in both groups in serum and breast milk samples. Conclusion Nutritional deficiencies in breastfeeding women after bariatric surgeries may in fact be less common than in control women in an inner city.


2015 ◽  
Vol 87 (1) ◽  
pp. 463-470 ◽  
Author(s):  
FERNANDA B.S. RESENDE ◽  
LARISSA Q. DE LIRA ◽  
EVELLYN C. GRILO ◽  
MAYARA S.R. LIMA ◽  
ROBERTO DIMENSTEIN

The influence of gestational diabetes on vitamin A deficiency in lactating women and, consequently, in their newborn has been verified through a cross-sectional case-control study conducted with volunteer puerperal women. The control group consisted of healthy women and the test group was composed of women with gestational diabetes. One hundred and seven women were recruited, corresponding to 71 controls and 36 cases. Personal, gestational and newborn data were collected directly from medical records during hospitalization. The retinol was determined in maternal colostrum and serum by High Performance Liquid Chromatography. Postpartum women with gestational diabetes were older, had more children and a higher prevalence of cesarean delivery. No difference was found in retinol concentration in maternal milk and serum between the groups. However, it was observed that 16.7% had vitamin A deficiency in the group of patients with diabetes and only 4.1% had such deficiency in the control group. Although no difference was found in colostrum and serum retinol concentration between women with and without gestational diabetes, the individual analysis shows that those with diabetes are at higher risk of being vitamin A deficient.


2013 ◽  
Vol 1 (1) ◽  
pp. 49-57 ◽  
Author(s):  
Gebremedhin Kidane ◽  
Kebede Abegaz ◽  
Afework Mulugeta ◽  
Pragya Singh

Vitamin A deficiency (VAD) is a public health problem in Ethiopia. Periodic supplementation of vitamin A (VA) capsules has developed as a short-term life saving intervention. However, it is important to shift from a subsidized periodic capsule distribution to a more sustainable food-based intervention, which could supply VA in the diet of low income rural communities. Orange flesh sweet potato (OFSP) was selected in this study as a potential raw material that used in food-based intervention, because of its high β-carotene content (naturally biofortified food). Therefore, this study aimed to analyze nutritional compostion of the VA enriched breads for pre-school children from OFSP and locally available Wheat flours of the study area. Blending of OFSP flour with whole Wheat flour (WWF) was conducted at laboratory by employing Complete Randomized Design (CRD). i.e. four bread blends of OFSP flour:WWF (0:100, 10:90, 20:80 and 30%:70%) were prepared and subjected to nutritional analysis at Ethiopian Health and Nutrition Research Institute (EHNRI). For proximate and β-carotene analysis AOAC (2000) standard method and manual column chromatography were used, respectively. The data were analyzed using SPSS, versions 16. Bread enriched with 30% OFSP flour can contribute 83.3 and 74.2% of VA to 3 and 4-6 years old children’s daily requirement, respectively. Therefore, WWF can be substituted by 30% OFSP flour for pre-school children’s bread making. A general trend of nutrient analysis showed that moisture, ash, fiber, β-carotene increased significantly (p < 0.05) as proportion of OFSP flour increased; while protein, fat, carbohydrate and energy content decreased. Therefore, OFSP flour enriched breads have added advantages nutritionally, especially in β-carotene. This will give responsible individuals, policymakers and donors more confidence to invest and work in OFSP for alleviation of VAD.


2016 ◽  
Vol 5 (1) ◽  
Author(s):  
Wici Septiyeni ◽  
Nur Indrawati Lipoeto ◽  
Joserizal Serudji

Abstrak             Berat badan lahir merupakan salah satu indikator kesehatan bayi baru lahir. Berat badan lahir dipengaruhi oleh berbagai faktor yang salah satunya adalah mikronutrien seperti: asam folat, zink dan vitamin A yang disinyalir memiliki hubungan dengan berat badan lahir.Tujuan penelitian ini adalah menentukan hubungan antara asupan asam folat, seng, dan vitamin A terhadap berat badan lahir. Penelitian ini merupakan cross sectional study pada 59 ibu hamil di Kabupaten Padang Pariaman. Pengumpulan data dilakukan dengan wawancara dan pengukuran berat badan lahir. Analisis statistik yang digunakan adalah uji korelasi Spearman. Hasil penelitian ini yaitu rata-rata umur ibu hamil sebesar 26,5424 tahun. Rata-rata berat badan lahir 3181,36 gram dan rata-rata tinggi badan ibu adalah 153,8305 cm. Rata-rata konsumsi asam folat subjek penelitian adalah 341,9525 ug, zink  5,0727 mg dan vitamin A 688,9300 RE. Hasil analisis menunjukkan tidak terdapat hubungan yang bermakna antara asupan asam folat dan berat badan lahir (p>0,05),asupan zink dan berat badan (p>0,05) dan asupan vitamin A dan berat badan lahir (p>0,05).bKesimpulan penelitian ini adalah bahwa tidak ada hubungan antara asupan asam folat, zink dan vitamin A ibu hamil trimester III terhadap berat badan lahir.Kata kunci: asam folat, zink, vitamin A, berat badan lahir, Ibu hamil trimester III AbstractBirth weight is an indicator of the health of the newborn. Birth weight is influenced by various factors like micronutrients such as: folic acid, zinc and vitamin A which allegedly had a relationship with birth weight. The objective of this study was to determine the relationship between the intake of folic acid, zinc, and vitamin A on birth weight. This study was a cross sectional study to 59 pregnant women in the district of Padang Pariaman. Data collection with interviews and birth weight measurements. Statistical analysis used the Spearman correlation test. The results of this study showed that the average maternal age of 26.5424 years and the average maternal height was 153.8305 cm. Average birth weight 3181.36 g. The average consumption of folic acid is 341.9525 ug, 5.0727 mg zinc and vitamin A 688.9300 RE. Analysis result showed no significant association between the intake of folic acid and birth weight (p > 0.05), zinc intake and birth weight (p > 0.05) and intake of vitamin A and birth weight (p > 0,05).The conclusion of this study is no relationship between the intake of folic acid, zinc and vitamin A of third trimester pregnant women toward birth weight.Keywords: folic acid, zinc, vitamin A , birth weight, third trimester pregnant women


2015 ◽  
Vol 12 (4) ◽  
pp. 27-38
Author(s):  
Rodolfo Moresco ◽  
Virgílio G. Uarrota ◽  
Aline Pereira ◽  
Maíra Tomazzoli ◽  
Eduardo da C. Nunes ◽  
...  

Summary In this study, the metabolomics characterization focusing on the carotenoid composition of ten cassava (Manihot esculenta) genotypes cultivated in southern Brazil by UV-visible scanning spectrophotometry and reverse phase-high performance liquid chromatography was performed. Cassava roots rich in β-carotene are an important staple food for populations with risk of vitamin A deficiency. Cassava genotypes with high pro-vitamin A activity have been identified as a strategy to reduce the prevalence of deficiency of this vitamin. The data set was used for the construction of a descriptive model by chemometric analysis. The genotypes of yellow-fleshed roots were clustered by the higher concentrations of cis- β-carotene and lutein. Inversely, cream-fleshed roots genotypes were grouped precisely due to their lower concentrations of these pigments, as samples rich in lycopene (redfleshed) differed among the studied genotypes. The analytical approach (UV-Vis, HPLC, and chemometrics) used showed to be efficient for understanding the chemodiversity of cassava genotypes, allowing to classify them according to important features for human health and nutrition.


Nutrients ◽  
2018 ◽  
Vol 10 (9) ◽  
pp. 1271 ◽  
Author(s):  
Sabina Bastos Maia ◽  
Maria Costa Caminha ◽  
Suzana Lins da Silva ◽  
Alex Rolland Souza ◽  
Camila Carvalho dos Santos ◽  
...  

Vitamin A is essential for mother and child; however, vitamin A deficiency (VAD) remains a public health issue in various countries, affecting around 19 million pregnant women. In Brazil, the scarcity and inconsistency of data have prevented the prevalence and epidemiological status of VAD from being established. This study aimed to analyze vitamin A nutritional status in women receiving prenatal care at a reference center in northeastern Brazil. A cross-sectional study was conducted with a sample of 676 women. Serum retinol was measured by high-performance liquid chromatography. Subclinical infection was detected by measuring C-reactive protein (CRP). The World Health Organization criteria were used in the prevalence analysis, VAD classification level, and CRP effect evaluation. The prevalence of VAD (serum retinol <0.70 μmol/L) was 6.2% (95% confidence interval 4.5–8.3). In the univariate analysis, the variables significantly associated with VAD (p < 0.05) were having <12 years of schooling, being in the third trimester of pregnancy, and anemia. In the final multivariate model, the variables that remained significantly associated (p < 0.05) were being in the third trimester of pregnancy and anemia. VAD constituted a mild public health problem in this sample of pregnant women and was associated with the third trimester of pregnancy and maternal anemia.


2018 ◽  
Vol 31 (3) ◽  
pp. 299-310
Author(s):  
Laísla França da Silva TELES ◽  
Adriana de Azevedo PAIVA ◽  
Liania Alves LUZIA ◽  
Flávia Emília Leite de LIMA-FERREIRA ◽  
Cecilia Maria Resende Gonçalves de CARVALHO ◽  
...  

ABSTRACT Objective To evaluate the relationship between serum retinol concentrations and subclinical infection in children from rural settlements. Methods A cross-sectional population-based study was carried out in nine rural settlements in the northeastern region of Brazil, involving 118 children aged 6 to 59 months. The relationship between serum retinol and C-Reactive Protein levels, an important marker of infectious and inflammatory processes, was investigated by multiple linear regression, controlling for demographic, socioeconomic and nutritional variables. Serum retinol and C-Reactive Protein were measured, respectively, by High Performance Liquid Chromatography and immunoturbidimetric assay in automated equipment. Results Vitamin A deficiency (retinol <0.70μmol/L) was identified in 9.3% of the children. C-Reactive Protein was the only predictor of retinol concentrations in the final regression model, causing a 0.728μmol/L reduction in retinol concentrations in the studied children (p=0.008). Conclusion Vitamin A deficiency is a problem of mild/moderate severity and measures to control infectious diseases in this population are fundamental to prevent and/or combat this problem.


2019 ◽  
Author(s):  
Zenebech Koricho ◽  
tefera Chane Mekonnen ◽  
Gudina Egata Atomssa ◽  
Sisay Eshete Tadesse

Abstract Vitamin A plays an important role in vision, cellular differentiation, embryonic development, reproduction, growth, and the immune system. Women who live in developing countries face a risk of undernutrition during pregnancy due to poverty, poor diet quality and quantity, and high fertility rate. This poor dietary problem could reflect women’s high risk of vitamin A deficiency. The major aim of this study was to determine the adequacy of vitamin A among pregnant women following antenatal care in health facilities of Dessie Town, Ethiopia, January 2017. Health facility-based cross-sectional study was conducted among 390 women that attended antenatal care in Dessie Town. The food groups from FAO based on 24 hour dietary recall was used to measure dietary intake Vitamin A and dietary diversity of women. Adequacy of vitamin A was determined from nutrient adequacy ratio after obtaining reports of nutrient intake from food composition table version III and IV in terms of B carotene and retinol equivalent respectively, based on the estimated average requirement recommendation of vitamin A, 370 RE/day for pregnant women. Multivariable Logistic regression analysis was done to identify associated factors of vitamin A adequacy.


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