scholarly journals Prior pandemics. looking to the past for insight into the COVID-19 pandemic

Author(s):  
Philip A. Mackowiak
Keyword(s):  
The Past ◽  
TAPPI Journal ◽  
2015 ◽  
Vol 14 (1) ◽  
pp. 51-60
Author(s):  
HONGHI TRAN ◽  
DANNY TANDRA

Sootblowing technology used in recovery boilers originated from that used in coal-fired boilers. It started with manual cleaning with hand lancing and hand blowing, and evolved slowly into online sootblowing using retractable sootblowers. Since 1991, intensive research and development has focused on sootblowing jet fundamentals and deposit removal in recovery boilers. The results have provided much insight into sootblower jet hydrodynamics, how a sootblower jet interacts with tubes and deposits, and factors influencing its deposit removal efficiency, and have led to two important innovations: fully-expanded sootblower nozzles that are used in virtually all recovery boilers today, and the low pressure sootblowing technology that has been implemented in several new recovery boilers. The availability of powerful computing systems, superfast microprocessors and data acquisition systems, and versatile computational fluid dynamics (CFD) modeling capability in the past two decades has also contributed greatly to the advancement of sootblowing technology. High quality infrared inspection cameras have enabled mills to inspect the deposit buildup conditions in the boiler during operation, and helped identify problems with sootblower lance swinging and superheater platens and boiler bank tube vibrations. As the recovery boiler firing capacity and steam parameters have increased markedly in recent years, sootblowers have become larger and longer, and this can present a challenge in terms of both sootblower design and operation.


2020 ◽  
Vol 15 ◽  
Author(s):  
Geeta Aggarwal ◽  
Manju Nagpal ◽  
Ameya Sharma ◽  
Vivek Puri ◽  
Gitika Arora Dhingra

Background: Biopharmaceuticals such as Biologic medicinal products have been in clinical use over the past three decades and have benefited towards the therapy of degenerative and critical metabolic diseases. It is forecasted that market of biologics will be going to increase at a rate of 20% per year, and by 2025, more than ˃ 50% of new drug approvals may be biological products. The increasing utilization of the biologics necessitates for cost control, especially for innovators products that have enjoyed a lengthy period of exclusive use. As the first wave of biopharmaceuticals is expired or set to expire, it has led to various opportunities for the expansion of bio-similars i.e. copied versions of original biologics with same biologic activity. Development of biosimilars is expected to promote market competition, meet worldwide demand, sustain the healthcare systems and maintain the incentives for innovation. Methods: Appraisal of published articles from peer reviewed journals, PubMed literature, latest news and guidelines from European Medicine Agency, US Food Drug Administration (FDA) and India are used to identify data for review. Results: Main insight into the quality requirements concerning biologics, current status of regulation of biosimilars and upcoming challenges lying ahead for the upgrading of marketing authorization of bio-similars has been incorporated. Compiled literature on therapeutic status, regulatory guidelines and the emerging trends and opportunities of biosimilars has been thoroughly stated. Conclusion: Updates on biosimilars will support to investigate the possible impact of bio-similars on healthcare market.


Author(s):  
Richard J. Simonson ◽  
Joseph R. Keebler ◽  
Mathew Lessmiller ◽  
Tyson Richards ◽  
John C. Lee

As cyber-attacks and their subsequent responses have become more frequent and complex over the past decade, research into the performance and effectiveness of cybersecurity teams has gained an immense amount of traction. However, investigation of teamwork in this domain is lacking due to the exclusion of known team competencies and a lack of reliance on team science. This paper serves to provide insight into the benefit that can be gained from utilizing the extant teamwork literature to improve teams’ research and applications in the domain of cyber-security.


Molecules ◽  
2020 ◽  
Vol 25 (5) ◽  
pp. 1059 ◽  
Author(s):  
Khadija El Hazzam ◽  
Jawhar Hafsa ◽  
Mansour Sobeh ◽  
Manal Mhada ◽  
Moha Taourirte ◽  
...  

Saponins are an important group found in Chenopodium quinoa. They represent an obstacle for the use of quinoa as food for humans and animal feeds because of their bitter taste and toxic effects, which necessitates their elimination. Several saponins elimination methods have been examined to leach the saponins from the quinoa seeds; the wet technique remains the most used at both laboratory and industrial levels. Dry methods (heat treatment, extrusion, roasting, or mechanical abrasion) and genetic methods have also been evaluated. The extraction of quinoa saponins can be carried out by several methods; conventional technologies such as maceration and Soxhlet are the most utilized methods. However, recent research has focused on technologies to improve the efficiency of extraction. At least 40 saponin structures from quinoa have been isolated in the past 30 years, the derived molecular entities essentially being phytolaccagenic, oleanolic and serjanic acids, hederagenin, 3β,23,30 trihydroxy olean-12-en-28-oic acid, 3β-hydroxy-27-oxo-olean-12en-28-oic acid, and 3β,23,30 trihydroxy olean-12-en-28-oic acid. These metabolites exhibit a wide range of biological activities, such as molluscicidal, antifungal, anti-inflammatory, hemolytic, and cytotoxic properties.


2019 ◽  
Vol 53 (1) ◽  
pp. 84-101 ◽  
Author(s):  
Mary Iliadis ◽  
Imogen Richards ◽  
Mark A Wood

‘Newsmaking criminology’, as described by Barak, is the process by which criminologists contribute to the generation of ‘newsworthy’ media content about crime and justice, often through their engagement with broadcast and other news media. While newsmaking criminological practices have been the subject of detailed practitioner testimonials and theoretical treatise, there has been scarce empirical research on newsmaking criminology, particularly in relation to countries outside of the United States and United Kingdom. To illuminate the state of play of newsmaking criminology in Australia and New Zealand, in this paper we analyse findings from 116 survey responses and nine interviews with criminologists working in universities in these two countries, which provide insight into the extent and nature of their news media engagement, and their related perceptions. Our findings indicate that most criminologists working in Australia or New Zealand have made at least one news media appearance in the past two years, and the majority of respondents view news media engagement as a professional ‘duty’. Participants also identified key political, ethical, and logistical issues relevant to their news media engagement, with several expressing a view that radio and television interviewers can influence criminologists to say things that they deem ‘newsworthy’.


Radiocarbon ◽  
2020 ◽  
pp. 1-8
Author(s):  
Alyssa M Tate ◽  
Brittany Hundman ◽  
Jonathan Heile

ABSTRACT Leather has been produced by a variety of methods throughout human history, providing researchers unique insight into multiple facets of social and economic life in the past. Archaeologically recovered leather is often fragile and poorly preserved, leading to the use of various conservation and restoration efforts that may include the application of fats, oils, or waxes. Such additives introduce exogenous carbon to the leather, contaminating the specimen. These contaminants, in addition to those accumulated during interment, must be removed through chemical pretreatment prior to radiocarbon (14C) dating to ensure accurate dating. DirectAMS utilizes organic solvents, acid-base-acid (ABA) and gelatinization for all leather samples. Collagen yield from leather samples is variable due to the method of production and the quality of preservation. However, evaluating the acid-soluble collagen fraction, when available, provides the most accurate 14C dates for leather samples. In instances where gelatinization does not yield sufficient material, the resulting acid-insoluble fraction may be dated. Here we examine the effectiveness of the combined organic solvent and ABA pretreatment with gelatinization for leather samples, as well as the suitability of the acid-insoluble fraction for 14C dating.


2002 ◽  
Vol 18 (2) ◽  
pp. 351-362
Author(s):  
Pablo A. J. Brescia ◽  
Scott M. Bennett

This interview with Mexican writer David Toscana ponders the current state of both Mexican and Latin American narrative and serves as an insight into his own works. Toscana's statements about the recurring themes in his narrative (failure, loneliness, characters put to the test, and a tendency to play with different time frames, especially in his novels) help illustrate some of the characteristics of his fiction, which, according to various critics, is one of the most promising today in Mexico. Also noteworthy are his comments about the tendency of writers from his generation (born in the 1960s and later) to reject the legacy of the "boom" writers. Toscana's own interest is to revisit history and tradition by constructing a different voice and a different vision, a new way of seeing and hearing both the past and the present. Esta entrevista con el escritor mexicano David Toscana trata de explorar el estado actual de la narrativa mexicana y latinoamericana, améén de servir como una aproximacióón a la incipiente obra de este autor. Las respuestas de Toscana sobre los temas recurrentes en su literatura (el fracaso, la soledad, los personajes sometidos a pruebas y una tendencia a proponer diferentes marcos temporales, especialmente en sus novelas) subrayan algunos rasgos de su ficcióón, la cual, segúún la críítica especializada, es una de las máás prometedoras en el panorama mexicano de hoy. De especial interéés son los comentarios de Toscana sobre la tendencia de los escritores de su generacióón a rechazar el legado del "boom" latinoamericano. Toscana reacciona contra ese rechazo y propone una voz personal que vuelva a la historia y a la tradicióón y plantee una nueva manera de ver el pasado y el presente de Mééxico.


1998 ◽  
Vol 27 (1) ◽  
pp. 53-83 ◽  
Author(s):  
Natalie Schilling-Estes

ABSTRACTThis article examines PERFORMANCE SPEECH in the historically isolated island community of Ocracoke, North Carolina. Over the past several decades islanders have come into increasingly frequent contact with tourists and new residents, who often comment on the island's “quaint” relic dialect. In response, some Ocracokers have developed performance phrases that highlight island features, particularly the pronunciation of/ay/ with a raised/backed nucleus, i.e. [Λ-1]. The analysis of/ay/ in the performance and non-performance speech of a representative Ocracoke speaker yields several important insights for the study of language in its social context. First, performance speech may display more regular patterning than has traditionally been assumed. Second, it lends insight into speaker perception of language features. Finally, the incorporation of performance speech into the variationist-based study of style-shifting offers support for the growing belief that style-shifting may be primarily proactive rather than reactive. (Keywords: Ocracoke, performance speech, style-shifting, stylistic variation, register, self-conscious speech.)


2021 ◽  
pp. 104365962110263
Author(s):  
Bindu Joseph ◽  
Michael Olasoji ◽  
Cheryl Moss ◽  
Wendy Cross

Introduction: In the past decade, there has been an influx of migrant nurses from India to Australia. Migrant professionals have specific transition needs associated with working in Mental Health (MH). This study aimed to explore the transition experience of overseas trained nurses from India working in Australian MH settings. Method: Hermeneutic phenomenology was the methodological approach used in the study. The participants ( N = 16) were overseas trained nurses from India. Data were collected through in-depth interview and analysed using thematic analysis. Results: The findings resulted in the identification of the following themes: (1) Living in dual culture, (2) Loneliness, (3) Discrimination, and (4) Feeling incomplete. Discussion: It is evident that the transition to work in MH in Australia was a journey of mixed experiences. While certain findings of this study are comparable with experiences of migrant nurses in other settings, it provides insight into those that are working in MH.


1995 ◽  
Vol 347 (1319) ◽  
pp. 21-25 ◽  

Over the past three or four years, great strides have been made in our understanding of the proteins involved in recombination and the mechanisms by which recombinant molecules are formed. This review summarizes our current understanding of the process by focusing on recent studies of proteins involved in the later steps of recombination in bacteria. In particular, biochemical investigation of the in vitro properties of the E. coli RuvA, RuvB and RuvC proteins have provided our first insight into the novel molecular mechanisms by which Holliday junctions are moved along DNA and then resolved by endonucleolytic cleavage.


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