A-121 Verbal Learning in Veterans with Mild Traumatic Brain Injury, Posttraumatic Stress Disorder, and Co-occurring Conditions
Abstract Objective The study examined how veterans with PTSD only, mTBI only, and co-occurring mTBI and PTSD acquire, encode, and consolidate verbal information at least three months post mTBI. Method This retrospective study examined 57 veterans (15 mTBI only, 6 PTSD only, 19 mTBI + PTSD, and 17 veteran controls) from a VA setting who were recruited through: polytrauma clinic referrals, introductory letters, and study flyers. The sample included male and female OIF/OEF veterans aged 18 to 70. Inclusion and exclusion criteria of participants were determined by the following measures: (a) Structured Interview for TBI Diagnosis, (b) Clinician-administered PTSD Scale, and (c) Letter Memory Test. One-way ANOVA evaluated group differences between the mTBI only, PTSD only, and mTBI + PTSD groups. A two-way ANOVA evaluated group differences between veterans with and without PTSD. Results The two-way ANOVA revealed that veterans with PTSD perform below the mTBI only and veteran control groups (F = 6.59, p = 0.01) on serial clustering forward strategy. The one-way ANOVA demonstrated that the mTBI + PTSD group performed below the mTBI only group on Trial 1 (F = 3.61, p = 0.04). Conclusions The mTBI + PTSD group performed worse than the mTBI only group on their ability to acquire verbal information. This result may suggest that the co-occurring effects of mTBI and PTSD negatively attribute to a veteran’s ability to focus and attend to new information. Veterans without PTSD were more likely to use a serial clustering strategy to recall information compared to Veterans with PTSD.