PSI-10 Effect of a plant extract mixture (pronutrients) on serum cytokines, intestinal integrity indicators and productive performance in broilers with raw soybean inclusion in the diet

Abstract Plant extracts contain active molecules called pronutrients that could replace antibiotic growth promoters (AGP) in order to improve intestinal integrity, optimize feed utilization and consequently, increase productive performance. The purpose of this study was to evaluate the effect of a mixture of pronutrients on hematological parameters, serum cytokins regulation, intestinal morphology, organs weight and productive parameters. The trial was conducted with 480 one-day-old male broilers of the Ross AP 308 divided into 3 groups: Group CON - Basal diet only, Group AB supplemented with bacitracin methylene disalicylate and Halquinol continuously, and Group PR with a mixture powder of pronutrients, respectively. The experiment lasted up to the 35th day of age. 3 % of crude soybean was added to all basal diets as a challenge for intestinal integrity. All data were statistically analyzed using ANOVA and P value less than 0.05 was set as statistically significant and 0.05 < P < 0.1 as tendency. A decrease of all serum cytokines (IL-1β, IL-6, IL-8, IL-10) in supplemented broilers with pronutrients was observed. The intestinal morphology parameters were better (length and villi depth) and performance parameters such as feed intake, body weight and feed conversion rate (FCR) throughout the trial were improved in broilers supplemented with pronutrients (P < 0.05). Dietary supplementation with a natural additive based on pronutrients demonstrated to be an effective alternative to AGP to improve intestinal morphology, productive performance and regulating hematological and immune values in broilers challenged with diets containing raw soybean.

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Alternatives to antibiotics in diets of weaned piglets

Ciência Rural ◽

10.1590/0103-8478cr20170074 ◽

2017 ◽

Vol 47 (12) ◽

Author(s):

Soraia Viana Ferreira ◽

Lívia Maria dos Reis Barbosa ◽

Marcos Henrique Soares ◽

Camila Schultz Marcolla ◽

Débora Muratori Holanda ◽

...

Keyword(s):

Organic Acids ◽

Basal Diet ◽

Negative Control ◽

Intestinal Morphology ◽

Daily Weight Gain ◽

Experimental Unit ◽

Average Weight ◽

Growth Promoter ◽

Feed Conversion ◽

Randomized Design

ABSTRACT: This experiment was conducted to evaluate the effect of growth promoter additives an alternative to antibiotics on performance, intestinal morphology and on microbiota of 21-to-35-day-old piglets. A total of 160 commercial crossbred piglets (males and females) with initial weight of 6.10±0.709kg were allotted in a completely randomized design with five treatments: Basal diet - Negative Control (NC); Basal diet + antibiotic (PC); Basal diet + mannanoligosaccharides (MOS); Basal diet + organic acids (OA), Basal diet + mannanoligosacharides + organic acids (MOS+OA), eight replicates and four piglets per experimental unit. The inclusion of additives in the diets had no effect (P>0.05) on the final average weight of piglets. Similarly, no effects (P<0.05) were observed on average daily feed intake and on average daily weight gain. The feed conversion improved (P<0.01) with the inclusion of additives in the diets compared to piglets fed with the NC. There was no effect (P>0.05) of the dietary additives on intestinal morphology and microbiota composition (enterobacteria and lactobacilli). Use of antibiotics, prebiotics, organic acids or prebiotics associated with organic acids in the diet improves feed conversion of piglets from 21 to 35 days of age. The additives have no major effects on piglets’ intestinal morphology and microbiota.

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Effect of Supplementing Beetroot (Beta Vulgaris Rubra) Powder and Its Aqueous Extract on Productive Performance of Growing Geese

IOP Conference Series Earth and Environmental Science ◽

10.1088/1755-1315/923/1/012028 ◽

2021 ◽

Vol 923 (1) ◽

pp. 012028

Author(s):

Saad K.J. Al-waeli ◽

Majid H.A. Alasadi ◽

Rabia J. Abbas

Keyword(s):

Weight Gain ◽

Beta Vulgaris ◽

Aqueous Extract ◽

Control Diet ◽

Basal Diet ◽

Conversion Ratio ◽

Feed Conversion Ratio ◽

The Other ◽

Productive Performance ◽

Feed Conversion

Abstract The present study aimed to investigate the influence of supplementing beetroot (Beta vulgaris rubra) powder and its aqueous extract on the productive performance of growing geese. A total of 180 one-day-old goslings chicks of Chinese white geese were randomly distributed among five treatment groups containing three replicates of 12 birds each. Five experimental diets were formulated as follows: Control diet without supplementation (T1). In the second and third treatments, the beetroot extract was supplemented at 15, and 30 (ml/l) in drinking water; 15, and 30 (g/kg) beetroot powder (T4, T5) in basal diet respectively. Results indicated significant (p≤0.05) improvement in average body weight and weight gain from the 2nd to 12th week and total weight gain in treatment T2 and T4, which achieved the highest values compared to the control. As for feed intake, the T3 in the 6th week, T1 in the 8th week, and T2 in the 10th week were consumed a greater amount of feed compared to the other treatments, while no significant differences appeared in the 2, 4, and 12 weeks of age and in the cumulative period. No significant differences in the feed conversion ratio at age 2, 10, and 12 weeks, while the T5 in the 4th week, T2 in the 6th week, and the T4 in the 8th week, and the cumulative period showed the better feed conversion ratio compared to the other treatments. In conclusion, the supplementation of beetroot extract at 15, 30 (ml/l) or beetroot powder at 15, 30 (g/kg) improved the productive performance of growing geese.

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Influence of Bacterial Organic Selenium on Blood Parameters, Immune Response, Selenium Retention and Intestinal Morphology of Broiler Chickens

10.21203/rs.2.23476/v2 ◽

2020 ◽

Author(s):

A. M. Dalia ◽

T. C. Loh ◽

A. Q. Sazili ◽

Anjas Asmara Samsudin

Keyword(s):

Broiler Chickens ◽

Hematological Parameters ◽

Basal Diet ◽

Blood Parameters ◽

Intestinal Morphology ◽

Control Group ◽

Villus Height ◽

Organic Selenium ◽

Significant Difference ◽

Immunity Response

Abstract Background: Several studies indicated that dietary organic selenium (Se) usually absorbed better than an inorganic source, with high retention and bioavailability. Dietary Se as an antioxidant element affects the immune system and hematological status in animals. Therefore, the aim of this study was to evaluate the effect of dietary supplementation of bacterial selenium as an organic source on hematology, immunity response, selenium retention, and gut morphology in broiler chickens. Results: The present results revealed that supplementation of inorganic Se was associated with the lowest level of RBC, HB, and PCV with significant difference than ADS18-Se. In the starter stage, both T2 and T5 were associated with the significantly highest IgG level compared to the basal diet, while all supplemented groups showed higher IgM levels compared to the control group. In the finisher phase, all Se supplemented groups showed significant (P ˂ 0.05) increases in IgG, IgA, and IgM levels compared to T1. Birds fed bacterial-Se showed high intestinal villus height and better Se retention more than sodium selenite. The organic selenium of ADS18 had a superior action in improving Se retention compared to ADS1 and ADS2 bacterial Se. Conclusion: Bacterial organic Se had a beneficial effect on the villus height of small intestine led to high Se absorption and retention. Thus, it caused a better effect of Se on hematological parameters and immunity response.

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Performance, intestinal histomorphology and bone composition of broiler chickens fed diets supplemented with genistein

South African Journal of Animal Science ◽

10.4314/sajas.v50i2.7 ◽

2020 ◽

Vol 50 (2) ◽

pp. 241-252

Author(s):

M. Glisic ◽

M. Boskovic ◽

M. Z. Baltic ◽

D. Sefer ◽

A. Radovanovic ◽

...

Keyword(s):

Broiler Chickens ◽

Basal Diet ◽

Intestinal Morphology ◽

Feed Conversion ◽

Broiler Performance ◽

Supplementation Period ◽

Wet Weight ◽

Small Intestinal ◽

Positive Effect ◽

Lactobacillus Spp

The effect of dietary genistein on performance, intestinal morphology, caecal Lactobacillus spp. count, and tibia composition in broiler chickens after 21 and 37 days of feeding was investigated. A total of 360 Cobb 500 broiler chickens (21 days old) were randomly allocated to five treatments with six replicates of 12 birds each. They were fed a basal diet (C) or a basal diet supplemented with 200 (T1), 400 (T2), 600 (T3) and 800 (T4) mg genistein/kg of feed. Genistein supplementation did not affect feed intake, but improved bodyweight, weight gain and feed conversion ratio (FCR) after 21 days, while 600 mg/kg led to a significant increase in FCR after 37 days of feeding. Plasma triglyceride level decreased with dietary genistein after 21 days, while increases were found in T3 and T4 groups after prolonged supplementation. Significantly improved duodenal and jejunal villus length and width, crypt depth and villus/crypt ratio were observed after the first and the second finishing periods, respectively, while adverse effects were found in the ileum for both periods. At 42 days old, greater spleen and heart weights were measured in broilers fed diets with 800 mg/kg than in other broiler groups. The shorter genistein supplementation period (21 days) of 200 and 400 mg/kg had a positive effect on tibia wet weight, ash and calcium (Ca) content, while 37 days of the higher genistein doses administered to the T2, T3 and T4 birds significantly increased caecal lactic acid bacteria (LAB) counts. Thus, recommended doses should not exceed 400 mg/kg. Keywords: broiler performance, blood triglyceride, Lactobacillus, prolonged fattening, small intestinal morphology

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Phosphorus on performance, hematological, biochemical, and bone parameters of growing pigs

Ciência Rural ◽

10.1590/0103-8478cr20150132 ◽

2016 ◽

Vol 46 (6) ◽

pp. 1076-1081 ◽

Cited By ~ 2

Author(s):

Jana Euclydes Drews ◽

Douglas Haese ◽

João Luís Kill ◽

Lucas Lemke Lorenzoni ◽

Rafael Bozini Pimentel ◽

...

Keyword(s):

Weight Gain ◽

Block Design ◽

Hematological Parameters ◽

Daily Intake ◽

Basal Diet ◽

Growing Pigs ◽

Daily Weight Gain ◽

Feed Consumption ◽

Available Phosphorus ◽

Feed Conversion

ABSTRACT: The purpose of this study was to assess the levels of available phosphorus (AP) in the diet of growing pigs selected for lean deposition on the hematological, biochemical, and bone performance parameters. A total of 64 commercial hybrid pigs (32 castrated males and 32 females; mean initial weight: 23.31±2.4kg; age: 55-90 days) were used. Animals were distributed into a randomized block design with four treatments, eight replicates, and two animals (one male and one female) per experimental unit. The treatments consisted of a basal diet and another three diets, which were obtained by supplementing the basal diet with dicalcium phosphate replacing the inert phosphate, resulting in four diets with 0.100, 0.180, 0.260, and 0.340% of available phosphorus. The levels of available phosphorus quadratically influenced the daily weight gain, feed consumption, and feed conversion, which increased up to the estimated levels 0.331; 0.330, and 0.302% of available phosphorus. Levels of phosphorus showed no influence on the hematological parameters, which remained within the reference values. Levels of available phosphorus increased linearly the ash and phosphorus contents in the metacarpal bone and decreased linearly the alkaline phosphatase activity. Levels of available phosphorus (0.331 and 0.302%, corresponding to a daily intake of 5.73 and 5.18g d-1) provided respectively the best results for weight gain and feed conversion in pigs with high genetic potential, without change in hematological parameters.

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Administration of loperamide and addition of wheat bran to the diets of weaner pigs decrease the incidence of diarrhoea and enhance their gut maturation

British Journal Of Nutrition ◽

10.1017/s0007114509992637 ◽

2009 ◽

Vol 103 (6) ◽

pp. 879-885 ◽

Cited By ~ 17

Author(s):

Francesc Molist Gasa ◽

Mauro Ywazaki ◽

Arantza Gómez de Segura Ugalde ◽

Rafael Gustavo Hermes ◽

Josep Gasa Gasó ◽

...

Keyword(s):

Transit Time ◽

Wheat Bran ◽

Control Diet ◽

Animal Health ◽

Average Daily Gain ◽

Basal Diet ◽

Protein Digestibility ◽

Intestinal Morphology ◽

Weaned Pigs ◽

And Performance

The influence of fibre inclusion and transit time regulation on the performance, health status, microbial activity and population, physico-chemical characteristics of the hindgut digesta and intestinal morphology in early weaned pigs were examined. For these experiments, wheat bran (WB) was used as fibre source and loperamide as a drug (LOP) to increase the digesta transit time. In Expt 1, a total of 128 early weaned pigs were randomly distributed in a 2 × 2 factorial combination of WB inclusion (0v.40 g/kg) and LOP administration (0v.0·07 mg/kg body weight) during 13 d. For Expt 2, a total of twenty-four piglets were allotted to three dietary treatments for 15 d with the same basal diet (control diet) as Expt 1; a diet with 80 g/kg of WB and the combination of WB and LOP. In Expt 1, LOP improved the average daily feed intake and average daily gain of the animals (P = 0·001 and 0·007, respectively). The same result was obtained when WB was combined with LOP. The WB–LOP group also showed a higher concentration of SCFA (P = 0·013), acetic acid (P = 0·004) and propionic acid (P = 0·093). On the other hand, WB inclusion reduced the organic matter and crude protein digestibility (P = 0·001) and tended to decrease the enterobacteria population (P = 0·089). In Expt 2, WB increased the butyric acid concentration (P = 0·086). We concluded that the inclusion of WB to modify the intestinal microbiota activity combined with LOP may be beneficial to animal health and performance.

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Analysis of the Productivity, Immunity, and Health Performance of Nile Tilapia (Oreochromis niloticus) Broodstock-fed Dietary Fermented Extracts Sourced from Saccharomyces cerevisiae (Hilyses): A Field Trial

Animals ◽

10.3390/ani11030815 ◽

2021 ◽

Vol 11 (3) ◽

pp. 815

Author(s):

Nermeen M. Abu-Elala ◽

Tamer El-Sayed Ali ◽

Naela M. Ragaa ◽

Sara E. Ali ◽

Reham M. Abd-Elsalam ◽

...

Keyword(s):

Saccharomyces Cerevisiae ◽

Oreochromis Niloticus ◽

Nile Tilapia ◽

Hematological Parameters ◽

Basal Diet ◽

Antioxidant Power ◽

Tnf Α ◽

Nile Tilapia Oreochromis Niloticus ◽

And Performance ◽

Strategic Solution

The present study aimed to evaluate the effect of dietary fermented extracts sourced from Saccharomyces cerevisiae (nucleotides, β-glucans and MOS) (Hilyses®) on the production and health of Nile tilapia (Oreochromis niloticus) broodstock, as well as on seed survival and performance. The trial was performed in a hatchery along the spawning season and continued in the laboratory to monitor the performance in fry and fingerlings. The broodstock were divided into two groups, (C) fed a basal diet and (H) fed 0.4% Hilyses. Blood and histological parameters, antioxidant power, cortisol level and the expression of some immune-related (TLR-2, IL-1β and TNF-α) and growth-related genes (MUC-2 and IGF-1) were measured. The obtained seeds were subdivided into four treatments: (C-C) fed a basal diet, (C-H) fed 0.4% Hilyses, (H-C) fed a basal diet and (H-H) fed 0.4% Hilyses. Results revealed that the dietary inclusion of Hilyses in the broodstock increased seed production, survival, hematological parameters, and antioxidant power. Moreover, it improved the intestinal microstructure and upregulated the immune- and growth-related genes. The growth indices of fry and fingerlings were significantly increased in all Hilyses-treated groups (p < 0.05). The performance in the (H-H) group significantly surpassed those of all groups. Therefore, dietary fermented yeast could be used as a strategic solution to sustain tilapia production.

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Effects of stale maize on growth performance, immunity, intestinal morphology and antioxidant capacity in broilers

Asian-Australasian Journal of Animal Sciences ◽

10.5713/ajas.19.0224 ◽

2020 ◽

Vol 33 (4) ◽

pp. 605-614 ◽

Cited By ~ 10

Author(s):

J. B. Liu ◽

H.L. Yan ◽

Y. Zhang ◽

Y.D. Hu ◽

H.F. Zhang

Keyword(s):

Antioxidant Capacity ◽

Growth Performance ◽

Interleukin 2 ◽

Relative Weight ◽

Basal Diet ◽

Interferon Γ ◽

Intestinal Morphology ◽

Bursa Of Fabricius ◽

Feed Conversion ◽

Factor Α

Objective: This study was conducted to determine the effects of stale maize on growth performance, immunity, intestinal morphology, and antioxidant capacity in broilers.Methods: A total of 800 one-day-old male Arbor Acres broilers (45.4±0.5 g) were blocked based on body weight, and then allocated randomly to 2 treatments with 20 cages per treatment and 20 broilers per cage in this 6-week experiment. Dietary treatments included a basal diet and diets with 100% of control maize replaced by stale maize.Results: The content of fat acidity value was higher (p<0.05) while the starch, activities of catalase and peroxidase were lower (p<0.05) than the control maize. Feeding stale maize diets reduced (p<0.05) average daily feed intake (ADFI) throughout the experiment, feed conversion ratio (FCR) during d 0 to 21 and the whole experiment as well as relative weight of liver, spleen, bursa of Fabricius and thymus (p<0.05) on d 21. Feeding stale maize diets decreased jejunum villus height (VH) and VH/crypt depth (CD) (p<0.05) on d 21 and 42 as well as ileum VH/CD on d 42. The levels of immunoglobulin G, acid α-naphthylacetate esterase positive ratios and lymphocyte proliferation on d 21 and 42 as well as lysozyme activity and avian influenza antibody H<sub>5</sub>N<sub>1</sub> titer on d 21 decreased (p<0.05) by the stale maize. Feeding stale maize diets reduced (p<0.05) serum interferon-γ, tumor necrosis factor-α, interleukin-2 on d 21 and interleukin-6 on d 21 and 42. Broilers fed stale maize diets had lower levels of (p<0.05) total antioxidative capacity on d 42, superoxide dismutase and glutathione peroxidase on d 21 and 42, but higher (p<0.05) levels of malondialdehyde on d 21 and 42.Conclusion: Feeding 100% stale maize decreased ADFI and FCR, caused adverse effects on immunity and antioxidant function and altered intestinal morphology in broilers.

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Probióticos Como Aditivos Dietéticos Para Cerdos. Una Revisión/Probiotics as Dietetic Additives for Pigs. A Review

KnE Engineering ◽

10.18502/keg.v5i2.6267 ◽

2020 ◽

Author(s):

V Morales-Oñate ◽

B Morales-Oñate

Keyword(s):

Animal Health ◽

Food Additives ◽

Live Weight ◽

Human Consumption ◽

Productive Performance ◽

Feed Conversion ◽

Growth Promoters ◽

Swine Industry ◽

Health Crisis ◽

Keywords Probiotics

Por varias décadas se ha utilizado en los sistemas intensivos y semi intensivos de producción porcina los antibióticos promotores de crecimiento, con la finalidad de controlar los problemas digestivos y respiratorios y mejorar la eficiencia. Sin embargo, su utilización en la alimentación de animales destinados al consumo humano, se relaciona con la crisis de salud global por la resistencia a los antimicrobianos. A nivel internacional, varias jurisdicciones respondieron a través de la restricción o prohibición del uso de estos productos. Esta situación condujo a que diferentes grupos de investigación se centraran en el estudio y desarrollo de alternativas para mantener la salud de los animales y el rendimiento productivo. Dentro de estas alternativas se incluyen probióticos que son uno de los aditivos alimentarios más estudiados y se definen como microorganismo(s) vivo (s) que cuando se adicionan en cantidades adecuadas influyen benéficamente en la salud del huésped. La aplicación de estos productos en la alimentación de cerdos puede modular la respuesta inmune y mejorar los parámetros zootécnicos de conversión alimenticia y ganancia de peso vivo final. Además, se pueden utilizar en el tratamiento de enfermedades infecciosas digestivas, como la diarrea, lo que aporta un beneficio económico importante en la industria porcina. En este estudio, se realizó una revisión de las diferentes etapas fisiológicas de cerdos con 23 citas bibliográficas y 50 referencias sobre la utilización de probióticos en la especie porcina como la utilización de probióticos en la alimentación. For several decades, antibiotic growth promoters have been used in intensive and semi-intensive systems of swine production, with the purpose of controlling digestive and respiratory problems and improving efficiency. However, its use in feeding animals destined for human consumption is related to the global health crisis due to resistance to antimicrobials. Internationally, several jurisdictions responded by restricting or prohibiting the use of these products. This situation led to different research groups focusing on the study and development of alternatives to maintain animal health and productive performance. These alternatives include probiotics that are one of the most studied food additives and are defined as live microorganism (s) that, when added in adequate amounts, beneficially influence the health of the host. The application of these products in pig feed can modulate the immune response and improve the zootechnical parameters of feed conversion and final live weight gain. In addition, they can be used in the treatment of digestive infectious diseases, such as diarrhea, which provides a significant economic benefit in the swine industry. In this study, a review was made of the different physiological stages of pigs with 23 citations and 50 references on the use of probiotics in swine as the use of probiotics in food. Palabras Claves: Probióticos, antibióticos, rendimiento productivo, salud del huésped. Keywords: Probiotics, antibiotics, productive performance, guest health.

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