scholarly journals Genetic variation in the social environment affects behavioral phenotypes of oxytocin receptor mutants in zebrafish

2020 ◽  
Author(s):  
D. Ribeiro ◽  
A.R. Nunes ◽  
M.C. Teles ◽  
S. Anbalagan ◽  
J. Blechman ◽  
...  
Keyword(s):  
Social Behavior ◽  
Social Environment ◽  
Oxytocin Receptor ◽  
The Other ◽  
Wild Type ◽  
Knock Out ◽  
The Social ◽  
Wide Range ◽  
Knockout Line ◽  
Genetically Modified Animals

AbstractOxytocin-like peptides have been implicated in the regulation of a wide range of social behaviors across taxa. On the other hand, the social environment, which is composed of conspecifics genotypes, is also known to influence the development of social behavior, creating the possibility for indirect genetic effects. Here we used a knockout line for the oxytocin receptor in zebrafish to investigate how the genotypic composition of the social environment (Es) interacts with the oxytocin genotype (G) of the focal individual in the regulation of its social behavior. For this purpose, we have raised wild-type or knock-out zebrafish in either wild-type or knock-out shoals and tested different components of social behavior in adults. GxEs effects were detected in some behaviors, highlighting the need to control for GxEs effects when interpreting results of experiments using genetically modified animals, since the social environment can either rescue or promote phenotypes associated with specific genes.

scholarly journals Genetic variation in the social environment affects behavioral phenotypes of oxytocin receptor mutants in zebrafish

eLife ◽  
2020 ◽  
Vol 9 ◽  
Author(s):  
Diogo Ribeiro ◽  
Ana Rita Nunes ◽  
Magda Teles ◽  
Savani Anbalagan ◽  
Janna Blechman ◽  
...  
Keyword(s):  
Social Behavior ◽  
Social Environment ◽  
Oxytocin Receptor ◽  
The Other ◽  
Wild Type ◽  
Knock Out ◽  
The Social ◽  
Wide Range ◽  
Knockout Line ◽  
Genetically Modified Animals

Oxytocin-like peptides have been implicated in the regulation of a wide range of social behaviors across taxa. On the other hand, the social environment, which is composed of conspecifics that may vary in their genotypes, also influences social behavior, creating the possibility for indirect genetic effects. Here, we used a zebrafish oxytocin receptor knockout line to investigate how the genotypic composition of the social environment (Gs) interacts with the oxytocin genotype of the focal individual (Gi) in the regulation of its social behavior. For this purpose, we have raised wild-type or knock-out zebrafish in either wild-type or knock-out shoals and tested different components of social behavior in adults. GixGs effects were detected in some behaviors, highlighting the need to control for GixGs effects when interpreting results of experiments using genetically modified animals, since the genotypic composition of the social environment can either rescue or promote phenotypes associated with specific genes.

scholarly journals The Emotional Lexicon Used by Male and Female Communication: Study of Balinese Language Used in South Kuta-Bali

2020 ◽  
Vol 3 (2) ◽  
pp. 364-372
Author(s):  
I Gusti Ayu Vina Widiadnya Putri ◽  
I Dewa Ayu Devi Maharani Santika
Keyword(s):  
Social Interaction ◽  
Social Behavior ◽  
Social Interactions ◽  
Qualitative Method ◽  
The Other ◽  
Male And Female ◽  
The Social ◽  
Data Source ◽  
Emotional Lexicon ◽  
Communication Study

The aims of this research is to analyse about the differences of emotional lexicon used by male and female communication in South Kuta-Bali when they used Balinese language in their daily interaction.  The scope of male and female is closely related to the social behavior which includes the social identity of male and female in society and this becomes the basis of how the language is used in this context of social. This research is interested to uncover more how people use language in terms of expressing their emotional in social interaction. This study is a sociolinguistic approach used the theory from Hickey, Raymon (2010). The data source in this study is the south Kuta community who use Balinese language in social interactions. The Data collection is done by observation, interview, recording and note taking and descriptive qualitative method is applied to analyze the data. The result of the analysis found that the emotional lexical is used by the male and female in their social interaction, it could mention that both Augmentatives and Euphemisms is used by male and female in their social interaction however the augmentative is mostly used by female in informal occasion. Balinese female often used prohibition instead of imperative in expressing her idea about ordering someone to do something. In the other hand, the male directly used imperative sentence in ordering something. He usually does not use many awkwardness to say his point in a conversation. This may be considered that the male often go to the straight point when expressing his idea. Keywords: Emotional Lexicon, Male and Female

Anti-sage

2017 ◽  
Author(s):  
John L. Culliney ◽  
David Jones
Keyword(s):  
New York ◽  
Educational Administration ◽  
Economic Life ◽  
The Other ◽  
New York University ◽  
Terrorist Organizations ◽  
Politics And Government ◽  
The Social ◽  
Wide Range ◽  
The World

Chapter 10 proceeds in light of our suggestion that sagely behavior is freely chosen, benign, yet powerful, and seeks cooperation in the world in ways that are positive, progressive, nurturing, and constructive in nature. This chapter, however, accounts for people who have been gifted with or have assiduously developed powers of rapport or charisma, achieving notable fractal congruence in the social, political, or economic life of institutions or communities but who have gone the other way. This phenomenon over a wide range of scale can elevate those who become destructive or aggrandizing to the ultimate detriment of society. Numerous followers can gravitate to the kind of socially-fractally-adept individual that we call an anti-sage. The chapter discusses examples of the antisage phenomenon in cults and terrorist organizations such as the People’s Temple and Aum Shinrykyo. In this narrative pertinent expressions of human selfness include: Protean self vs. fundamentalist self and parochial altruism. Also explored are politics and government, notably the administration of George W. Bush, creed-based religions, particularly Christianity and Islam, and aggrandizement in educational administration, such as that of John Sexton’s presidency of New York University.

scholarly journals Mutational Replacement of Leu-293 in the Class C Enterobacter cloacae P99 β-Lactamase Confers Increased MIC of Cefepime

2002 ◽  
Vol 46 (6) ◽  
pp. 1966-1970 ◽  
Author(s):  
Sergei B. Vakulenko ◽  
Dasantila Golemi ◽  
Bruce Geryk ◽  
Maxim Suvorov ◽  
James R. Knox ◽  
...  
Keyword(s):  
Kinetic Parameters ◽  
Broad Spectrum ◽  
Random Mutagenesis ◽  
Enterobacter Cloacae ◽  
The Other ◽  
Mutant Enzyme ◽  
Wild Type ◽  
Wild Type Enzyme ◽  
Wide Range ◽  
Class C

ABSTRACT The class C β-lactamase from Enterobacter cloacae P99 confers resistance to a wide range of broad-spectrum β-lactams but not to the newer cephalosporin cefepime. Using PCR mutagenesis of the E. cloacae P99 ampC gene, we obtained a Leu-293-Pro mutant of the P99 β-lactamase conferring a higher MIC of cefepime (MIC, 8 μg/ml, compared with 0.5 μg/ml conferred by the wild-type enzyme). In addition, the mutant enzyme produced higher resistance to ceftazidime but not to the other β-lactams tested. Mutants with 15 other replacements of Leu-293 were prepared by site-directed random mutagenesis. None of these mutant enzymes conferred MICs of cefepime higher than that conferred by Leu-293-Pro. We determined the kinetic parameters of the purified E. cloacae P99 β-lactamase and the Leu-293-Pro mutant enzyme. The catalytic efficiencies (k cat/Km ) of the Leu-293-Pro mutant β-lactamase for cefepime and ceftazidime were increased relative to the respective catalytic efficiencies of the wild-type P99 β-lactamase. These differences likely contribute to the higher MICs of cefepime and ceftazidime conferred by this mutant β-lactamase.

Optimal Contracting Model in a Social Environment and Trust-Related Psychological Costs

2013 ◽  
Vol 13 (1) ◽  
pp. 271-284 ◽  
Author(s):  
Suren Basov ◽  
M. Ishaq Bhatti
Keyword(s):  
Social Norms ◽  
Social Environment ◽  
Point Of View ◽  
The Other ◽  
Trade Off ◽  
Optimal Contracting ◽  
The Social ◽  
The One ◽  
Contracting Model

AbstractMost research in contract theory concentrated on the role of incentives in shaping individual behavior. Recent research suggests that social norms also play an important role. From a point of view of a mechanism designer (a principal, a government, and a bank), responsiveness of an agent to the social norms is both a blessing and a curse. On the one hand, it provides the designer with extra instruments, while on the other it puts restrictions on how these new and the more conventional instruments can be used. The main objective of this paper is to investigate this trade-off and study how it shapes different contracts observed in the real world. We consider a model in which agent’s cost of cheating is triggered by the principal’s show of trust. We call such behavior a norm of honesty and trust and show that it drives incentives to be either low powerful or high powerful, eliminating contracts with medium powerful incentives.

scholarly journals A Study on the Use of Social Networks by Turkish and German University Students in the Globalization Process

2018 ◽  
Vol 6 (11a) ◽  
pp. 88
Author(s):  
Nurhayat Çelebi ◽  
Gülenaz Selçuk ◽  
Huriye Sevinç Peker
Keyword(s):  
Social Networks ◽  
University Students ◽  
Social Networking ◽  
Social Environment ◽  
Social Impact ◽  
Communication Technologies ◽  
The Other ◽  
Impact Scale ◽  
The Social ◽  
Significant Difference

Today's rapidly evolving technology is expanding the use of innovative communication technologies and their usage areas. to traditional communication technologies today; smartphones, laptop computers, handheld computers, and tablets are also added. Wireless communication technology removes time and space limits, allowing people to communicate both voiced and visual whenever and wherever they wish. Every day, millions of people communicate with each other through social networking networks and share their experience day by day with other network users. The social networks that people often use are also affecting interpersonal relationships. The purpose of this research is to determine the aims of Turkish and German university students to use social networks and how effective social influence is in interpersonal communication. A total of 338 students, 236 Turkish students studying at Karabük University and 102 German students studying at Kassel University in Germany, participated in the research in the academic year of 2016-2017. As a data collection tool, a 10-item questionnaire developed by Özdayı (2010) and a 13-item, “social impact scale” were used. 4 items of the questionnaire used in the study were arranged in the form of "yes-no" and the other items were arranged by the participants to point to the box opposite to the statement they found appropriate. Each participant can mark a few of the options suitable for him / her. Secondly, the "social impact scale" is 5-Likert type. In the face of each article (5) from its fully appropriate expression, (1) Not suitable at all, a gradation to the statement was made. Percentages, mean and t test for binary comparison were used as statistical analysis in the study. According to research findings; all students have smartphones and they use whatsapp, facebook and youtube most from social networks. By students, social media is used to look at mails, homework, study, follow current events, read news, communicate with friends, make new friends, get informed about activities, share videos and photos and have fun. Also by students travel, shopping, technology and cinema blogs are the most preferred. In the survey, in the social dimension of social networks; there was no significant difference between the groups regarding "communication, self-expression, staying out of the group, becoming popular, joining groups, getting social environment, getting status in social environment and sharing". On the other hand, social networking has become an important means of communication and interaction among people today. For this reason, academicians should encourage students who are interested in new technology and communication applications to support the achievement of up-to-date information within the context of lifelong learning, and to conduct research for their own development in the teaching-learning process.

scholarly journals OPTIMALISASI PERKEMBANGAN SOSIAL PADA ANAK USIA PRA-SEKOLAH DENGAN TERAPI BERMAIN ASSOSIATIVE PLAY MENGGUNAKAN BOLA DI TK AISYIYAH PRAJURIT KULON MOJOKERTO

2015 ◽  
Vol 1 (2) ◽  
pp. 26
Author(s):  
Ima Rahmawati
Keyword(s):  
Social Behavior ◽  
Social Development ◽  
Play Therapy ◽  
Sampling Technique ◽  
School Age Children ◽  
School Age ◽  
Purposive Sampling ◽  
The Social ◽  
Wide Range ◽  
Post Test

ABSTRAKBermain pada anak akan mengembangkan berbagai kemampuan dan anak akan belajar untuk beradaptasi dengan lingkungan, sehingga anak akan cepat mengatasi masalah yang timbul. Perilaku sosial merupakan salah satu indikator untuk menilai bagaimana pertumbuhan optimal anak. Tujuan penelitian ini untuk mengetahui pengaruh terapi bermain Assosiative Play menggunakan bola terhadap perkembangan sosial anak usia pra-sekolah di TK Aisyiyah Prajurit Kulon Kota Mojokerto. Penelitian ini menggunakan pendekatan analitik korelasi dengan desain pre-experimental one group pre-post test. Sampel penelitian ini sebanyak 26 murid, menggunakan teknik purposive sampling. Variabel independen dalam penelitian ini adalah terapi bermain asosiative play menggunakan bola dan variabel dependen dalam penelitian ini adalah perkembangan perilaku social anak. Data dikumpulkan dengan lembar observasi perilaku sosial anak pra-sekolah. Hasil penelitian secara statistik terbukti ada pengaruh terapi bermain Assosiate Play menggunakan bola terhadap perkembangan sosial pada anak usia pra-sekolah (p=0.001). Salah satu manfaat bermain terapi adalah mengembangkan perilaku sosial anak karena anak akan belajar berinteraksi, dan menyesuaikan diri dengan lingkungan. Diharapkan lembaga pendidikan khusus TK Aisyiyah dapat menerapkan bermain terapi terutama Assosiative Play untuk perkembangan social anak usia pra-sekolah.Kata kunci: Assosiative play, terapi bermain, perilaku sosial, anak usia pra-sekolahABSTRACTPlaying at the child will develop a wide range of capabilities and the child would learn to adapt with the environment. Social behavior is one indicator to assess how far optimal growth in children. The purpose of this study was to determine the effect of Assosiate using ball play therapy in social development in pre-school age children in Aisyiyah kindergarten of Prajurit Kulon Mojokerto. This study uses an analytical approach correlation with pre-experimental design of one group pre-post test. Samples of this study were 26 students, using purposive sampling technique. The independent variable in this study was the asosiative using ball play therapy and the dependent variable in this research was the development of the social behavior of children. Data were  collected with social behavior observation sheet. The results proved statistically there was an effect of  Assosiative using ball play therapy in social development in pre-school age children in Aisyiyah kindergarten of Prajurit Kulon Mojokerto (p=0.01). One of the benefits of play therapy is to develop the social behavior of the child because the child will learn to interact and adapt to the environment. Education institutions especially for in Aisyiyah kindergarten can apply Assosiative play therapy for social development of pre-school age children.Keywords: Assosiative play, play therapy, social behavior, pre-school age child DOWNLOAD FULL TEXT PDF >>

scholarly journals LGBT dalam Perspektif Alkitab Sebagai Landasan Membentuk Paradigma Etika Kristen terhadap Pergaulan Orang Percaya

2020 ◽  
Vol 1 (1) ◽  
pp. 1-14
Author(s):  
Christian Bayu Prakoso ◽  
Yonatan Alex Arifianto ◽  
Aji Suseno
Keyword(s):  
Social Media ◽  
Social Environment ◽  
Preventive Measures ◽  
The Other ◽  
Faith Formation ◽  
The Social ◽  
God's Love ◽  
Access Information ◽  
Lgbt People ◽  
The Church

The LGBT phenomenon is increasingly spreading among the wider community. The existence of social media allows everyone to access information quickly and easily. The church, which is directly related to the social environment, also takes an attitude towards this phenomenon. There are many different attitudes raised by a particular church or denomination. Therefore, this paper aims to find out carefully about the Bible's view of LGBT as the basis for forming a Christian ethical paradigm. The result of this research is that LGBT acts are a sin in God’s view. God does not want people to commit LGBT acts. But on the other hand, as an agent that embodies the application of God's love, the church is required to continue to follow LGBT people and provide faith formation and preventive measures to the congregation.

scholarly journals PSK DALAM FRAMING TIGA MONOLOG/PROSTITUTE ON THREE MONOLOGUES FRAMING

Aksara ◽  
2022 ◽  
Vol 33 (2) ◽  
pp. 215-228
Author(s):  
Resti - Nurfaidah
Keyword(s):  
Sexual Harassment ◽  
Social Environment ◽  
Descriptive Analysis ◽  
Family Members ◽  
Theoretical Concept ◽  
The Other ◽  
Analysis Method ◽  
Father Figure ◽  
Environmental Attitude ◽  
The Social

Abstrak Makalah berjudul “PSK dalam Framing Tiga Monolog” ditulis untuk membahas tokoh PSK dalam ketiga monolog yang bertemakan kehidupan PSK, yaitu Monolog Tanda Tanya (Anggi Eka Putri), Monolog Pelacur (Putu Wijaya), danMonolog Cahaya (Lenny Koroh dan Silvester Hurit). Penelitian dalam makalah tersebut dibatasi pada penampilan tokoh PSK dalam ketiga monolog, pembahasan PSK berdasarkan konsep framingdan representasi, serta sikap lingkungan terhadap tokoh PSK. Penelitian ini merupakan kualitatif dengan metode analisis deskriptif komparatif pada ketiga monolog. Konsep teoretis yang digunakan dalam penelitian ini adalah framing Pan Konscki, serta representasi Hall. Berdasarkan penelitian diperoleh hasil berikut: (1) PSK yang ditampilkan dalam ketiga monolog ditunjukkan sebagai perempuan yang terjerumus. Tokoh PSK mudah terjerumus ke dalam dunia hitam, tetapi sulit keluar dari dunia tersebut; (2) Berdasarkan hasil framing dan representasi, tokoh PSK merupakan korban yang tidak mampu mengatasi dampak pelecehan seksual atau pemerkosaan. Kekecewaan berkepanjangan tidak pernah teratasi karena tokoh PSK dipertemukan dengan lingkungan atau pihak yang berkompeten menjerumuskan perempuan itu di dunia hitam, misalnya teman atau kekasih. Konflik dengan sosok ayah juga dianggap sebagai pencetus utama tercetusnya seorang perempuan ke dunia hitam; serta (3) sikap lingkungan terhadap tokoh PSK menunjukkan bahwa dunia hitam para PSK bukan dunia yang ramah. PSK tidak dapat ke luar dari dunia tersebut dengan mudah sementara ia harus bertanggung jawab untuk kehidupan anggota keluarganya.  Selain itu, ia harus menanggung risiko besar selama menjalani profesinya, tanpa perlindungan apa pun. PSK bukan saja mengalami kesulitan di dunianya sendiri, melainkan pula di dunia luar. Lingkungan sosial sulit menerima eksistensi mereka, bahkan cenderung merendahkan. Tidak jarang lingkungan sosial dapat menjadi pencetus atau pendukung terjerumusnya seorang perempuan menjadi PSK. Kata kunci: PSK, framing, pelecehan, korban Abstract"PSK in Framing of Three Monologues" discussed prostitute figures on the three prostitute themed monologues:  Monolog Tanda Tanya (Anggi Eka Putri), Monolog Pelacur (Putu Wijaya), dan Monolog Cahaya (Lenny Koroh dan Silvester Hurit). The research was limited to (1) the appearance of prostitute figures in all three monologues, (2) prostitute discussions based on the result of framing and representation, also (3) environmental reactions towards prostitutes. This research is qualitative with a comparative descriptive analysis method on all three monologues. The theoretical concept used in this research was Pan Konscki’s framing, as well as Hall representation of the. The result was below. First, PSK displayed in all three monologues was shown as women who were extremely trapped. PSK figures easily fell into the site, but were difficult to get out from. Second, based on the framing and representation, prostitute figures were victims who were unable to cope with the effects of sexual harassment or rape. Prolonged disappointment had never been resolved because they met with the environment or the competent party plunged them into such world, such as friends or lovers. Conflict with a father figure was also considered as the main originator of the emergence of a woman into the sit. Three, the environmental attitude towards the prostitute shew that the surroundings of prostitutes were not a friendly world. They won’t let to be out of it easily while, on the other hand, they had to be responsible for the lives of their family members. In addition, they were close to high-risks of their profession, without any protection. Prostitutes were not only experience difficulties in their own world, but also in the outside world. The social environment also hardly accepted their existence, even tends to be condescending. Sometimes, it could be the originator or supporter of a woman becoming a prostitute. Keywords: prostitute, framing, harrashment, victims

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