scholarly journals Epidemiological characteristics of deaths from COVID-19: an analysis at almost three months of the first confirmed case in Peru

Author(s):  
Willy Ramos ◽  
Juan Arrasco ◽  
Jhony A. De La Cruz-Vargas ◽  
Luis Ordóñez ◽  
María Vargas ◽  
...  

SUMMARYOBJECTIVETo determine the epidemiological characteristics of deaths from COVID-19 in Peru from March 28 to May 21, 2020, 85 days after the report of the first confirmed case.MATERIAL AND METHODSCase series type study. Deaths from various sources were investigated, including the COVID-19 Epidemiological Surveillance and the National System of Deaths. Deaths that met the definition of a confirmed case and had a positive (reactive) result of RT-PCR or rapid test were considered for the analysis. From these sources, epidemiological variables were obtained and a time analysis was performed, defining as the pre-hospital time the time from the onset of symptoms to the date of hospitalization and hospital time from the date of hospitalization to the date of death.RESULTS3,244 confirmed deaths were included in the study. Deaths were more frequent in males (71.8%), elders (68.3%), residents of the department of Lima (41.8%), and others from the coast (37.7%). In 81.3% of cases, the death occurred in a public hospital, 16.0% died at home, shelter, penitentiary institution, public highway, or in transit to a hospital, and 31.1% had some comorbidity.Statistical difference was observed in pre-hospital time according to age group (p <0.001) and gender (p = 0.037), being significantly higher in adults, elders, and women. There was a statistically significant difference in hospital time according to geographic area, showing a significantly shorter time in the departments of the coast (p <0.001) and Andean region (p = 0.014) compared to Lima. The cases that were seen in private clinics (p = 0.001) survived longer than those seen in public hospitals.CONCLUSIONDeaths from COVID-19 occur mainly in male, elders, on the coast, with considerable deaths at home, in shelters, penitentiaries, public roads, or in transit to a hospital. Pre-hospital time is affected by age group and gender; while, hospital time is also influenced by the region of origin and the health care provider.

2019 ◽  
Vol 01 (04) ◽  
pp. 20-28
Author(s):  
Aqib Nazeer ◽  
Shahid Ali ◽  
Imran Tipu

Background The prevalence of hepatitis B virus (HBV) in the Pakistani population has been reported previously, however, studies with a city-oriented approach and focus on age and gender distribution are very limited. Therefore, the current study was designed to unravel the age-wise and gender wise prevalence of HBV in Lahore, Pakistan. Methods A total of 350 blood samples of both male and female patients who visited National Genetic Laboratory, Lahore between February 2019 and July 2019 and who were suspected of HBV infection were screened. Sandwich based ELISA was used to detect rapid hepatitis B surface antigen (HbsAg) according to the manufacturer’s instruction. Real time PCR was used to detect HBV using HBV Rotor Gene PCR kit. Results Out of 350 blood samples screened for HBV infection (n= 350), 180 (51.43%) were of males and 170 (48.57%) were of females. Mean age (years) with SD (standard deviation) of the screened population was 37.22 ± 12.16 years. Overall, 224 samples (64%) were found to be positive for HBV infection. In our study, the number of females with this infection (52.24%) was slightly higher than males (47.76%). However, we observed no statistically significant difference (p = 0.225) between them. Conclusion Our study concludes that HBV is highly prevalent in Lahore, Pakistan. Females are slightly more susceptible to HBV infection as compared to males. This study also reports that HBV is more prevalent in the 20-40 age group.


2019 ◽  
Vol 56 (1) ◽  
pp. 10-14 ◽  
Author(s):  
Fangio FERRARI ◽  
Elisa Cantú Germano DUTRA ◽  
Henrieli Correia ZANARDI ◽  
Bruno Lorenzo SCOLARO ◽  
Odemari Miranda FERRARI

ABSTRACT BACKGROUND: The bacterium Helicobacter pylori is strongly associated with the development of gastric adenocarcinoma. Currently, the prevalence in developed countries is 40%, but this value increases considerably in developing countries, which can reach rates bigger than 90%. OBJECTIVE: The objective of this study was to determine the mean and annual prevalence of Helicobacter pylori infection in patients from Itajaí during the period from July 1992 to April 2016, as well as the gender and age groups most affected. METHODS: After consent of the clinical director of the Gastroclinica Itajaí and confidentiality commitment about the research, the database of the Endoscopy Service of the clinic was evaluated. All the patients who underwent their first upper digestive endoscopy with urease test and/or histological analysis were included. The data were submitted to statistical analysis of prevalence by gender, age group and years of study, with subsequent correction through the confidence interval. RESULTS: The mean prevalence of Helicobacter pylori infection thru all years of study was 50.07%. With the calculation of the annual prevalences, it was evident the gradual reduction of infection in the population of Itajaí, that was 81.3% in 1992, declining to 33% in the year of 2016. When classifying the prevalence of infection by gender, it was higher in males (53.59%), and gender distribution by age group showed no statistically significant difference among genders between the ages of 40 and 80 years. In relation to the age group, the highest prevalence was in the group between 40 and 49 years. CONCLUSION: Although this study is retrospective and based on endoscopic database analysis, without access to clinical data of patients such as prior use of proton pump inhibitor and antibiotics to endoscopy, its results are important because they may reflect the current panorama of Helicobacter pylori infection in the city under study, where it has been presenting a gradual reduction of prevalence over the years, with current rates similar to that of developed countries (33%). Future studies are needed to confirm our data.


2003 ◽  
Vol 27 (1) ◽  
pp. 91-94 ◽  
Author(s):  
Ali Mentes ◽  
Julide Atukeren

The aim of the study was to evaluate toothbrushing management and ability of children in relation to age and gender. The study population consisted of 75 children and were divided into three equal groups as 3-5, 6-8 and 9-11 years of age.The grip type during toothbrushing was recorded on videotape.The most preferred grip types were distal (73%) followed by power (43%) and oblique grips (29%). There were a statistically significant differences between age groups and the grip types (p&lt;0.001) but no significant difference was seen between boys and girls in grip preferences (p&gt;0.05).The mean duration of toothbrushing was shorter in 3-5 years of age group (28 seconds) than the 6-8 and 9-11 age groups (35 and 47 seconds respectively).


2017 ◽  
Vol 92 (2) ◽  
pp. 161-167 ◽  
Author(s):  
I. Colovic Calovski ◽  
A. Barac ◽  
Z. Golubovic ◽  
A. Karamarkovic ◽  
S. Mitrovic ◽  
...  

AbstractCystic echinococcosis (CE) is an endemic helminthic disease caused by infection with Echinococcus granulosus metacestodes. Although CE is endemic in the Balkan region, the exact epidemiology remains unknown. We conducted a case-series study with the aim of evaluating the correlation between seropositivity, socio-epidemiological data, pre-operative treatment with albendazole and viability of protoscolices in human hepatic hydatid cysts. Consecutive patients with hepatic CE underwent surgery to extract E. granulosis cysts. The viability of protoscolices was measured by their ability to absorb 0.1% eosin. Socio-epidemiological data were collected and serological testing was performed. In the present study, 38 patients (28 adults and 10 children) with hepatic CE were treated surgically. The scolex viability test was positive in 30/38 (79%) samples. All patients with non-viable cysts had seronegative results. The viability test was positive in 11/12 (91.6%) adult patients with pre-operative albendazole treatment and in 9/10 (90%) children. Statistically more patients were from an urban area compared with a rural area (65.8% vs. 15.7%). The increasing number of stray dogs shedding E. granulosus eggs in urban public areas in the Balkans might be the reason for the significant difference in the rate of infection between urban and rural areas in the present study. In addition, uncontrolled slaughtering of livestock, common in rural settlements, and feeding the infected viscera to dogs, favour the maintenance of the parasite cycle. We believe that the results of our study will encourage physicians, veterinarians and health authorities to initiate a programme to prevent and control CE in the Balkan region.


2017 ◽  
Vol 10 (1) ◽  
pp. 155-166 ◽  
Author(s):  
Sabina Alispahic ◽  
Enedina Hasanbegovic-Anic

The goal of this research was to examine age and gender differences in mindfulness on Bosnian general population. The study was conducted on a sample of 441 participants from the general population, from twelve cities in Bosnia and Herzegovina. As a measure of mindfulness we used Five Factor Mindfulness Questionnaire. Results showed that older participants’ scores were higher than for younger participants for all aspects of mindfulness. There was found a statistically significant difference between the three age groups on the subscales of Acting with awareness F(2, 435) = 7.39, p < .01 and of Non-judging of inner experience F(2, 428) = 5.67, p < .01. We found statistically significant difference for the Acting with awareness between 20-32 age group (M = 28.57, SD = 5.66) and 33-49 age group (M = 31.01, SD = 5.00, t(292) = -3.91, p < .001), and between 20-32 age group and 50+ group (M = 30.14, SD = 5,86, t(290) = -2.32, p < .05). Also, there was a significant difference for the Non-judging between 20-32 age group (M = 24.77, SD = 5.80) and 33-49 age group (M = 26.65, SD = 5.09, t(288) = -2.94, p < .01), and between 20-32 age group and 50+ group (M = 26.49, SD = 4.90, t(287) = -2,71, p < .05). According to the t-test results, there was statistically significant gender difference between the subscales Observing (t(432) = -2.259, p < .05) and Acting with awareness (t(432) = 2.197, p < .05), women scored higher than men on the subscale Observing, while men exhibited higher scores on the subscale Acting with awareness. Results of this research showed that there were found significant age and gender differences for some aspects of mindfulness in the sample of Bosnian general population.


2021 ◽  
Vol 31 (Supplement_3) ◽  
Author(s):  
D Marinov ◽  
E Valtcheva

Abstract Background Adolescent idiopathic scoliosis affects 2-3% of all teenagers. It is one of the most common chronic conditions in this age group, but studies on the physical activity (PA) of AIS patients are scarce. The available trials report conflicting findings when comparing the PA of children with AIS to healthy controls. Considering its possible role in the development of AIS and the potential benefits of PA, the topic should be further researched. This study aims to investigate the subject by comparing the physical activity of children with AIS to a group of healthy peers. Methods The study included 80 teenagers (aged 11-18 years) with AIS and 65 healthy age and gender-matched controls from Varna, Bulgaria. Data was collected after receiving informed consent from the parents. Children with chronic conditions (except AIS) were excluded. Information on AIS was taken from the available medical documentation. Data on PA during the last 7 days was collected via a standardized physical activity questionnaire for adolescents (PAQ-A). PAQ-A results vary from 1 (lowest PA) to 5 (highest PA). PAQ-A=2.75 has been found to correspond to the minimum recommended by WHO for this age group - 60mins of daily moderate to vigorous PA. Results None of the participants with AIS reported reduced PA due to impaired or restricted physical functions. The majority of children (78.8%) had mild scoliotic curvatures (Cobb angle 10°-20°). The mean PAQ-A score in AIS cases was 2.59 compared to 2.88 in controls. There was a statistically significant difference in PAQ-A score between the two groups (t = 2.722, p &lt; 0.001). 59% of AIS had a PAQ-A score under 2.75, indicating that they do not meet the minimum PA recommendation by WHO, compared to 31% of the control group. Conclusions Patients with AIS have significantly lower PA than their healthy peers. The majority of children with AIS do not meet the minimum PA recommendations by the WHO. Key messages Our study reveals that children with AIS and mild curvatures have lower PA than their healthy peers despite not reporting impaired or restricted physical functions. Future prospective studies should investigate whether PA plays a role in the etiology of AIS.


Author(s):  
V. G. Akimkin ◽  
S. N. Kuzin ◽  
T. A. Semenenko ◽  
A. A. Ploskireva ◽  
D. V. Dubodelov ◽  
...  

The ongoing COVID-19 pandemic around the world and in Russia remains a major event of 2020. All over the world, research is being conducted to comprehensively study the patterns and manifestations of the epidemic  process. The main quantitative characteristics of SARS-CoV-2 transmission dynamics among the population, based on the data of official monitoring over the current situation, play an important role in the development of  the epidemiological surveillance system.The aim of this study is to explore the peculiarities of age-gender distribution of COVID-19 patients in Moscow.Material and methods. The data related to the epidemiological characteristics of age-gender structure of COVID-19 patients in Moscow between March 19, 2020 and April 15, 2020, at different stages of the  epidemic were retrospectively analyzed.Results and discussion. The mean age of COVID-19 patients in Moscow was 46,41±20,58 years. The gender ratio (male/female) among the patients was 52.7/47.3 %, wherein the indicators varied depending upon the  age. Male/female ratio in the age group “under 39” stood at 53.7/46.3 %, and “over 40 years of age” – at  39.3/60.7 %. The predominant age range among male cases was 19 to 39 years old – 35.4 %, while among female patients – 40–59 years (36.5 %). The age distribution of patients in Moscow is indicative of the fact that COVID-19 is a disease that primarily affects older age groups. The age structure of all COVID-19 cases during the observation period is characterized by predominance of adult patients over 19 years of age – 92,7 % (92,6–92,8 %), the share of patients aged 40–59 years is 35,7% (35,5–35,9 %). The differences in the age distribution in males and females are as follows: in the male cohort, the age groups 19–39 years old and 40–59 years old prevail – 35.4 % (35.1–35.7 %) and 34.9 % (34.6–35.2 %), respectively. The age group 40–59 years old – 36.5 % (36.3–36.8%) dominates in the female cohort. 


2021 ◽  
pp. 000313482110322
Author(s):  
Brian J. Specht ◽  
Caroline R. Buse ◽  
Janey R. Phelps ◽  
Michael R. Phillips ◽  
Sarah D. Chiavacci ◽  
...  

Background Virtual Reality (VR) is used as an effective tool for distraction and as an adjunct for pain management. This study was conducted to compare VR to standard iPad use after surgery and examine its effect on pain score and opioid consumption. Methods This was a randomized controlled study, with stratification by surgery type, age group (7-12yo, 13-18yo) and gender. Pain and anxiety were assessed with validated scales (STAI, FACES, VAS, FLACC) and outcomes were compared between each group. Results 50 of the 106 enrolled patients used the VR device. After adjusting for age, gender, and STAI, patients had a decreased FLACC score while using the VR device compared to the iPad group (odds ratio 2.95, P = .021). The younger patients were found to have lower FLACC scores while using the VR device (odds ratio 1.15, p=0.044); this finding was most significant when patients used the VR device for 20-30 minutes (odds ratio 1.67, P = .0003). Additionally, after adjusting for treatment group, gender, and STAI, the younger patients had higher odds of withdrawal or exclusion from the study (odds ratio 1.18, P = .021). No significant difference in opioid consumption between the groups was found. Discussion Virtual reality was well tolerated and more effective in decreasing pain during the immediate postoperative period than iPad use. Despite a slightly higher withdrawal rate, younger patients benefited more from the intervention.


Author(s):  
Jorge L. D. GAZINEO ◽  
Beatriz M. TROPE ◽  
Juan P. MACEIRA ◽  
Sílvia B. MAY ◽  
Janice M. C. de O. COELHO ◽  
...  

The aim of this case series was to describe the clinical, laboratory and epidemiological characteristics and the presentation of bacillary angiomatosis cases (and/or parenchymal bacillary peliosis) that were identified in five public hospitals of Rio de Janeiro state between 1990 and 1997; these cases were compared with those previously described in the medical literature. Thirteen case-patients were enrolled in the study; the median age was 39 years and all patients were male. All patients were human immunodeficiency virus type 1 (HIV-1) infected and they had previous or concomitant HIV-associated opportunistic infections or malignancies diagnosed at the time bacillary angiomatosis was diagnosed. Median T4 helper lymphocyte counts of patients was 96 cells per mm³. Cutaneous involvement was the most common clinical manifestation of bacillary angiomatosis in this study. Clinical remission following appropriate treatment was more common in our case series than that reported in the medical literature, while the incidence of relapse was similar. The frequency of bacillary angiomatosis in HIV patients calculated from two of the hospitals included in our study was 1.42 cases per 1000 patients, similar to the frequencies reported in the medical literature. Bacillary angiomatosis is an unusual opportunistic pathogen in our setting.


2020 ◽  
Author(s):  
Giordano Perez Gaxiola ◽  
Rosalino Flores Rocha ◽  
Julio Cesar Valadez Vidarte ◽  
Melissa Hernandez Alcaraz ◽  
Gilberto Herrera Mendoza ◽  
...  

Background: The SARS-CoV-2 virus may affect both adults and children. Although the disease, named COVID-19, has a lower prevalence in infancy and has been described as mild, the clinical characteristics may vary and there is a possibility of complications. Objectives: To describe the clinical and epidemiological characteristics of pediatric cases confirmed in the state of Sinaloa, Mexico, during the first three months of the pandemic, and of children admitted with COVID-19 to a secondary hospital. Methods: This case series includes all patients with SARS-CoV-2 infection confirmed by PCR testing, identified in the state epidemiological surveillance system between March 1 and May 31, 2020. Confirmed patients admitted to the Sinaloa Pediatric Hospital (HPS) during the same dates are also described. Results: Fifty one children with SARS-CoV-2 were included, 10 of the admitted to HPS. The median age was 10 years. The more frequent symptoms were fever (78%), cough (67%) and headache (57%). Most cases were mild or asymptomatic. Three patients with comorbidities died. Only 4 of 10 patients identified in HPS had been admitted with the diagnosis of possible COVID-19. Conclusions: SARS-CoV-2 infection in children was mostly mild or asymptomatic, but with a wide range of clinical presentations.


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