scholarly journals The effect of a supplement of chromium (picolinate) on the level of blood glucose, insulin activity and changes in laboratory evaluation of the ejaculate of breeding boars

Author(s):  
Pavel Horký ◽  
Petra Jančíková ◽  
Ladislav Zeman

The experiment was based on feeding the organic form of chromium (picolinate) and the assessment of its effect on the level of blood glucose, insulin activity and changes in the laboratory values of the ejaculate (sperm motility, ejaculate volume, sperm concentration and per cent of pathological sperm) in breeding boars. The experiment involved 40 boars divided into two equal groups. Boars of the experimental group (n = 21) received 181.81 μg of chromium per kg of feed ration (FR) administered perorally, in the control group (n = 19) chromium intake was not increased. The chromium supplement significantly (P < 0.05) increased cell absorption of blood glucose in the experimental group of boars as against the control group. There was no difference in insulin activity between the two groups. Changes in laboratory values of the ejaculate were evaluated and no significant differences were discovered in any of the parameters. During the experiment the sperm concentration and motility were absolutely the same in boars of both groups; it can therefore be concluded that increasing the level of chromium in the feed ration of boars of the experimental group had no direct effect on these parameters. It was the same in the case of the ejaculate volume which gradually decreased between periods 1 and 4, in boars receiving chromium by 12.8 % and in the control group by 8.1 %. The beneficial effect of chromium was seen in the reduced count of pathological sperm in boars in periods 3 and 4 of tests as against boars of the control group. In spite of the considerable 26.3 % difference between the groups this decrease was not statistically significant. Data evaluation revealed a significant correlation (P < 0.01) between the number of samplings per boar and sperm concentration. A correlation (P < 0.05) was also detected between the ejaculate volume and sperm concentration

2020 ◽  
Vol 14 (03) ◽  
pp. 124-127
Author(s):  
Somia Iqbal ◽  
Noman Sadiq ◽  
Saad Siddiqui ◽  
Hira Iqbal

Background: Obesity is a prevailing metabolic disorder that affects the functioning of the male reproductive system. Excessive adipose tissue enhances reactive oxygen species generation and is linked with male infertility. Spinach has demonstrated antioxidant effects. The present study was conducted to determine the antioxidant effects of spinach on sperm parameters in obese Sprague Dawley rats. Subjects and methods: This randomized control study was conducted at the animal house of the National Institute of Health Islamabad, Islamic International Medical College, Cosmesurge International Hospital, Rawalpindi, and Apollo lab, Islamabad, Pakistan from April 2016 to March 2017. Forty male Sprague Dawley rats having an age of 8 weeks and weight 160-200g were tagged from number 1 to 40. Every third rat was randomly allocated to control Group A (n=13) and remaining into the Experimental group (n=27). Rats of control Group A was given a standard diet while a high-fat diet was given to Experimental group rats to induce obesity for the duration of six weeks. Weight (g) was measured weekly and obesity was confirmed when rats attain more than 20% weight when compared with that of rats of control Group A. Then, after obesity induction, the experimental group was alienated into the obesity control group (Group B) and spinach treated group (Group C). For sample, rats of Group A and Group B were sacrificed, and the cauda epididymis of each rat was placed in a Petri dish containing normal saline and cut into pieces to allow the release of sperm and then sperm parameters (sperms concentration, motility, and morphology) were recorded under the microscope. Then, spinach (5% hot water extract) along with the persistence of fat diet was administered to Group C for 4 weeks and finally, sperm parameters were measured in this group. Results: Sperm concentration/ml, motility (%), and normal morphology (%) of Group B rats were significantly decreased as compared to Group A rats. However, sperm concentration/ml, motility (%), and normal morphology (%) of Group C (spinach treated group) rats was significantly increased (p<0.001) as compared to Group B (obesity control group) rats after administering spinach. Conclusion: The addition of Spinach in a normal diet regimen restores normal sperm morphology, improves sperm motility and concentration.


2020 ◽  
Vol 2 (1) ◽  
pp. 48

Sleep is defined as an easily reversible periodic state marked by the absence of wakefulness. Studies have shown that university students tend to have a diminished amount of sleep. This would lead to the loss of concentration, daytime sleepiness, and reduced academic performances. The aim of this study was to investigate the effects of yoga on overall sleep quality, depression, anxiety, stress, and blood glucose levels. A total of 88 participants with 44 students in each group, control and experimental, were recruited from Universiti Tunku Abdul Rahman based on the outcome of the Godin Shephard questionnaire. A total score of less than 14 was considered mild hence falling into the control group while above 14 and had practiced yoga for a minimum of 6 weeks were placed in the experimental group. The participants were required to self-administer a set of questionnaires consisting of socio-demographic information, the Pittsburgh Sleep Quality Index (PSQI) questionnaire and Depression, Anxiety, Stress Scores. Three components of sleep, namely the habitual sleep efficiency, sleep disturbances, and daytime dysfunctions, were better in the experimental group compared to the control one. Depression, anxiety, stress, and blood glucose levels also appeared to be more desirable in the experimental group with yoga students. It was found that blood glucose levels were positively correlated to the Global PSQI score, depression, anxiety, and stress measures in this study. In conclusion, yoga-practicing students have healthier sleep patterns, negative emotional states, and blood glucose levels. In order to obtain more conclusive findings, similar studies should be carried out in different universities with larger sample size and for longer periods.


2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Mrs. Vanitha. S s ◽  
Dr. Pramjit kaur

Challenges in lifestyle, such as increasesin energy intake and decreasesin physical activity are causing overweight and obesity leading to epidemic increases in type II Diabetes Mellitus. The research approach used for this study was evaluative approach and the research design was true experimental design. 60 patients with type II diabetes, 30 in experimental group and 30 in control group were selected for this study by using purposive sampling technique. Data was collected with the help of self-structured interview schedule. Descriptive statistics (frequency, percentage, mean and standard deviation) and inferential statistics (chi-square, paired ‘t’ test) were used to analyse the data and to test the hypotheses. In the experimental group,the pre-test mean score was 2.966, mean percentage was 59% and standard deviation was 1.129 and in post-testmean score was 2.533, mean percentage was 50.66% and standard deviation was 1.074 with effectiveness of 8.34% and paired‘t’ test value of t=3.971,which was statistically significant (p<0.05) which is an evidence ofthe effectiveness of Amla juice in reducing blood glucose level. Comparison of blood glucose levels in experimental and control groups, shows that the value is statistically highly significant, as was observed from the unpaired ‘t’ test value of 13.39 with P value of <0.05, which is an evidence indicatingthe effect of Amla juice in reducing postprandial blood glucose levels. The resultsfound that the administration of Amla juice did have aneffect in reducing blood glucose level in the experimental group. By comparing the findings of pre-test and post test between the experimental group and the control group,the effect was identified (assessed). The study concluded that the Amlajuice is effective in reducing blood glucose level.


2017 ◽  
Vol 36 (04) ◽  
Author(s):  
Neha Tiwari ◽  
D. M. Shere

The present study was conducted to show the long term effect of low glycemic index (GI) finger millet (Eleusine coracana) buns (GI = 36.57) on diabetics. This case control clinical trial was conducted on 30 type 2 diabetic subjects who were equally divided into 2 groups: experimental group (EG) and control group (CG). The EG patients were supplemented with four (200 g) finger millet flour buns for 60 days in comparison to control group without having any buns supplementation. All the samples supplemented to experimental group provided 23-25g of total dietary fibre per day. The metabolic parameters studied were serum glucose, serum cholesterol, serum LDL, serum HDL, serum triglycerides and serum VLDL. Blood glucose levels (both fasting and post prandial) and lipid profile (at fasting) of the subjects were assessed at baseline and after 60 days of supplementation. Significant reduction was recorded in fasting blood glucose (13.75%), post prandial blood glucose (14.43%), serum cholesterol (4.41%) and serum LDL (11.22%) and also a decrease in serum triglycerides (5.11%) and VLDL (4.74%). Serum HDL increased significantly by 14.98 per cent. Thus, it is concluded that finger millet as a low GI food product leads to modest improvement in long-term glycemic and lipidemic control in type 2 diabetics.


2018 ◽  
Vol 1 (3) ◽  
Author(s):  
Baoxuan Lin ◽  
Xiquan Weng ◽  
Yu Chen ◽  
Yan Meng

Objective The purpose of this study was to explore the function of Lycium Barbarum juice on exercise stress regulation when male university students drank Lycium Barbarum juice during increasing resistance exercise, by observing the effects of oral Lycium Barbarum juice on the blood glucose, serum Adrenocorticotropic Hormone (ACTH), insulin and glucagon concentration. Methods 21 to 22, healthy, 28 male university students participated in the study. They were randomly divided into a control group (n=16)and an experimental group(n=12). All participants completed four-stage incremental load movement for a total of 32 days. The exercise intensity of four stages was 60% VO2max, 70% VO2max, 80% VO2max and 90% VO2max, respectively. Each stage was exercised every-other-day, 4 times per stage and 1 hour each time. During the exercise, each subject in the experimental group drank 100 ml of 100% Lycium Barbarum juice before going to bed every day. Before the experiment and the morning after the end of each phase, a participant’s elbow-venous blood was collected to separate the serum. In all serum substances, the concentrations of ACTH, insulin, glucagon were detected by ELISA system. Fasting blood glucose concentration was detected by a blood glucose meter (Kyoto GT-1640 glucose meter, Japan). SPSS 17.0 software was used for statistical analysis. Results 1) The serum ACTH concentration of the subjects continually increased with the progress of the incremental load exercise and reached the highest at the end of the fourth stage. Compared with the increase in the control group (P<0.05), the experimental group was more significant (P<0.01). 2) Compared with before the experiment, both control group and experimental group were no obvious changes of blood glucose concentration in the first and second stages, and the control group was significantly decreased in the third and fourth stages (P<0.05), while the experimental group was not (P>0.05). 3) During the increasing load exercise, the changes of insulin in serum of the participants were basically the same. The insulin level increased significantly at the end of the first stage and decreased successively at the end of the last three stages. At the end of the fourth stage, the serum insulin level of the control group decreased more significantly (P<0.05) than the experimental group (P>0.05). 4) The glucagon concentration in the control group continued to increase with the increase of the load. By contrast, the glucagon concentration in the experimental group gradually decreased at the end of the first stage and then increased at the end of the fourth stage. However, all of the increase and decrease are not statistically significant. Conclusions During increasing resistance exercise, drinking Lycium Barbarum juice can increase the ability of the body to regulate Adrenocorticotropic Hormone (ACTH), insulin and glucagon through the exercise stress regulation systems, the Hypothalamic-Pituitary-Adrenal Cortical Hormone system (HPA) and the Sympathetic-Adrenal Medullary system. It plays an important role in maintaining blood sugar levels during increasing resistance exercise and accelerating post-exercise function recovery after exercise.


2018 ◽  
Vol 5 (1) ◽  
pp. 69-74
Author(s):  
Jing-Jing Chao ◽  
Ya-Zhuo Xue

Abstract Objective We aimed to explore the effect of a new health education model on continuous nursing care in elderly patients with diabetes mellitus who had undergone an operation for fracture. Methods Convenience sampling was used to select 59 elderly patients with diabetes mellitus and fracture. New health education methods were used, and patient parameters were evaluated before and after the intervention. Results Evaluation of medication, reasonable diet, regular exercise, blood glucose monitoring, and regular follow-up compliance were significantly improved in the experimental group compared to the control group (P < 0.05). There were also significant differences between groups in fasting blood glucose, 2-hour postprandial blood glucose, triglyceride, high-density lipoprotein, and low-density lipoprotein levels (P < 0.05); however, the differences between groups in terms of glycosylated hemoglobin and total cholesterol levels were not statistically significant (P > 0.05). Finally, the functional recovery and mental health of the experimental group were significantly better than those of the control group (P < 0.05). Conclusions The implementation of a menu of voluntary services in community-based continuous nursing provided standardized nursing care for elderly patients with fracture and diabetes mellitus and improved their quality of life.


Author(s):  
Zhang Yingli

Background: Diabetic foot is one of the main reasons that seriously affect the quality of life and disability. Good foot care can prevent 85% amputation of diabetic foot patients. The purpose of this study is to explore the effects of interactive education with conversation map on foot care behaviors among elderly diabetic patients with high-risk diabetic foot.Methods: 96 elderly diabetic patients in Endocrinology Department of the Second Affiliated Hospital of Shandong First Medical University from January to December in 2020 were selected as the research objects. According to the parity of the last two digits of the hospitalization number, the odd number was divided into the control group and the even number was divided into the experimental group. The control group was given traditional health education and interactive education with conversation map for diabetic foot launched by the international diabetes federation was added to the experimental group. After 3 months of intervention, fasting blood glucose, 2 hours postprandial blood glucose, glycosylated hemoglobin and foot care behaviors of the two groups were observed.Results: The fasting blood glucose, 2 hours postprandial blood glucose, glycosylated hemoglobin and foot care behaviors of the experimental group were significantly better than those of the control group and the difference was statistically significant (p<0.05).Conclusions: The interactive education with conversation map can effectively improve the foot care behaviors of elderly diabetic patients with high-risk diabetic foot, and then prevent the occurrence of diabetic foot.


2020 ◽  
Vol 2020 ◽  
pp. 1-8
Author(s):  
Fang Tang ◽  
Xuan Lin

Type 2 diabetes represents a serious societal health problem due to the vulnerability to cardiovascular events. Diet therapy is the most basic treatment for type 2 diabetes. The present study was conducted to study the effect of a fasting-mimicking diet and specific meal replacement foods on blood glucose control in patients with type 2 diabetes. Our study included 100 patients with type 2 diabetes who underwent a physical examination which were enrolled and randomly assigned as 50 patients each to the test group (with low energy-specific meal replacement meals during a fasting-mimicking diet) and the control group (with specific meal replacement foods given normal adult doses). After 4 months, efficacy indicators which were fasting blood glucose, 2-hour postprandial venous blood glucose, and glycosylated haemoglobin of the experimental group were all lower than those of the control group ( P < 0.05 ); observation indicators that include body mass index, waist circumference, blood lipids (triglyceride, cholesterol, and low-density lipoprotein), and blood pressure levels were all lower than the control group, and high-density lipoprotein levels were all higher than the control group (all P < 0.05 ). Both groups of fasting blood glucose, 2-hour postprandial venous blood glucose, and blood pressure had a relatively stable downward trend, but the experimental group had a more significant decline. In conclusion, the study revealed that a fasting-mimicking diet and specific meal replacement foods can safely and effectively reduce weight and improve metabolic syndrome in patients with type 2 diabetes.


2020 ◽  
Vol 16 (4) ◽  
pp. 625-630
Author(s):  
Yong-Taek Kim ◽  
Zong-Do Jo ◽  
Hung-Mun Pang ◽  
Chan-Ok Paek ◽  
Chang-Sok Mun

Background: The earliest determinant of progression to type 2 diabetes is a loss of early insulin secretion, a defect which results in postprandial hyperglycemia and is often believed to reflect insulin resistance. In Asian countries including our country, noodle is the traditional food which has been eaten from ancient times and is taken one or two times a day. The functional noodle is a staple meeting nutritional requirements for the prevention and treatment of Impaired Glucose Tolerance (IGT). Methods: FNs were prepared using the noodle making machine according to Barak et al. with slight modifications. After giving FNs prepared by three mixing ratios of main materials to the IGT-induced rats for 30 days, the levels of postprandial 2h-blood glucose in all experimental groups and control group were measured to determinate the optimal mixing ratio of FN. After the IGT subjects in experimental group ate 200g of FN (dried weight) in exchange for a lunch for 60 days, the levels of postprandial 2h-blood glucose and of TG and TC in serum were measured to compare with that in the control group who had not undergone control in their diet. Results: After 30 days of experiment, the levels of postprandial 2h-blood glucose in rats of pl group 4 were lowest. The levels of postprandial 2h-blood glucose in the control group that most of them had not undergone control in their diet were increased, but that in experimental group who had taken FN decreased from 30 days of experiment to be significantly different after 60 days. The concentrations of serum TC and TG of IGT subjects in the experimental group were decreased compared with that in the control group, but significance among two groups was achieved only in the concentration of serum TC. Conclusion: FN made in the 4:3:3 ratio of powder of corn, powder of bean cake defatted and powder of peeled whole potato is more effective to decrease the levels of postprandial 2h-blood glucose. FN is a staple type of functional food that could be used for the treatment of IGT.


2011 ◽  
Vol 68 (8) ◽  
pp. 650-654 ◽  
Author(s):  
Gordana Bukara-Radujkovic ◽  
Dragan Zdravkovic ◽  
Sinisa Lakic

Background/Aim. Balancing strict glycemic control with setting realistic goals for each individual child and family can optimize growth, ensure normal pubertal development and emotional maturation, and control long term complications in children with type 1 diabetes (T1DM). The aim of this study was to evaluate the efficacy of short-term continuous glucose monitoring system (CGMS) application in improvement of glycemic control in pediatric type 1 diabetes mellitus (T1DM) patients. Methods. A total of 80 pediatric T1DM patients were randomly assigned into the experimental and the control group. The experimental group wore CGMS sensor for 72 hours at the beginning of the study. Self-monitored blood glucose (SMBG) levels and hemoglobin A1c (HbA1c) levels were obtained for both groups at baseline, and at 3 and 6 months. Results. There was a significant improvement in HbA1c (p < 0.001), in both the experimental and the control group, without a significant difference between the groups. Nevertheless, after 6 months the improvement of mean glycemia was noticed only in the experimental group. This finding was accompanied with a decrease in the number of hyperglycemic events and no increase in the number of hypoglycemic events in the experimental group. Conclusions. The results suggest that the CGMS can be considered as a valuable tool in treating pediatric T1DM patients, however further research is needed to more accurately estimate to what extent, if any, it outperforms intensive self-monitoring of blood glucose.


Sign in / Sign up

Export Citation Format

Share Document