scholarly journals Lung function: population epidemiology and concordance in Australian children aged 11–12 years and their parents

BMJ Open ◽  
2019 ◽  
Vol 9 (Suppl 3) ◽  
pp. 53-62 ◽  
Author(s):  
Liam Welsh ◽  
Gayan Kathriachchige ◽  
Tahmeed Raheem ◽  
Anneke C Grobler ◽  
Melissa Wake ◽  
...  
Keyword(s):  
Lung Function ◽  
Population Sample ◽  
Correlation Coefficients ◽  
Cross Sectional Study ◽  
Forced Expiratory Volume ◽  
International Standards ◽  
Linear Regression Models ◽  
Cross Sectional ◽  
Parents And Children ◽  
Z Scores

ObjectivesTo describe the epidemiology of lung function in Australian children aged 11–12 years and their parents, and explore the degree of intergenerational concordance.DesignCross-sectional study (the Child Health CheckPoint) nested in the Longitudinal Study of Australian Children (LSAC).SettingAssessment centres in seven Australian cities and eight regional towns, February 2015 to March 2016. Families unable to attend a clinic appointment were offered a home visit during the same period.Participants1874 families (53% of all eligible) participated in the study. Lung function data were available for 1759 children aged 11–12 years and 1774 parents (1668 biological pairs).Outcome measuresParticipants completed spirometry with measures including forced expiratory volume in 1 s (FEV1), forced vital capacity (FVC) and mid expiratory flow (MEF), converted to z-scores using Global Lung Initiative equations. Parent–child concordance was assessed using Pearson’s correlation coefficients and multivariable linear regression models. Survey weights and methods accounted for LSAC’s complex sampling, stratification and clustering within postcodes.ResultsAll lung function measures followed approximately normal distributions. Mean (SD) for FEV1, FVC and MEF z-scores in children were 0.33 (1.07), 0.83 (1.14) and −0.48 (1.09), respectively. Mean (SD) in parents were 0.28 (1.10), 0.85 (1.15) and −0.45 (1.10), respectively. Parent FEV1, FVC and MEF were associated with child lung function with significant positive correlation coefficients (0.22, 95% CI 0.17 to 0.26; 0.24, 95% CI 0.20 to 0.29; and 0.24, 95% CI 0.20 to 0.29, respectively).ConclusionsMean lung volumes were larger but with smaller airway size than international standards for both parents and children in this population sample. Modest associations between parent and child lung function highlight the potential for better identification of ‘at risk’ populations. Therefore, these findings may aid the development of health policy that aims to prevent the onset or limit the progression of lung disease.

scholarly journals Lung Function in Traditional Shellfish Divers in Southern Chile—A Cross-Sectional Study

2021 ◽  
Vol 18 (20) ◽  
pp. 10641
Author(s):  
Lorenz Mark ◽  
Marie Astrid Garrido ◽  
Dennis Nowak ◽  
Katja Radon ◽  
Laura Wengenroth
Keyword(s):  
Lung Function ◽  
Cross Sectional Study ◽  
Forced Expiratory Volume ◽  
Southern Chile ◽  
Linear Regression Models ◽  
Sectional Study ◽  
Long Term Effects ◽  
Cross Sectional ◽  
Diving Depth ◽  
Chi Squared

The long-term effects of diving on human lung function are controversially discussed. We investigated the lung function of traditional shellfish divers in southern Chile and identified risk factors for reduced lung volumes in divers. In a cross-sectional study, we assessed lung function in traditional shellfish divers and fishermen from two fishing communities. Male divers and fishermen aged 18–60 years were recruited. Participants’ health and diving habits were assessed via standardized questionnaires. Descriptive statistics, chi-squared tests and multiple linear regression models were applied. Through door-to-door sampling, we recruited 112 divers and 63 fishermen (response 67%). Valid spirometries were obtained from 98 divers and 52 fishermen. Divers had higher values of forced vital capacity (FVC, Beta = 0.28, 95% confidence interval (CI): 0.09; 0.47) and forced expiratory volume in 1 s (FEV1, Beta = 0.23, 95%-CI: 0.07; 0.39) compared to fishermen. Among divers, lower values of FVC (Beta = −0.35, 95%-CI: −0.65; −0.05) were found in those with a high diving frequency, while diving depth was associated with higher values of FVC (Beta = 0.28, 95%-CI = 0.04; 0.52). Professional divers had better lung function compared to fishermen. However, among divers, lung function decreased with cumulative diving exposure, warranting approval in future studies to ensure the safety and health of divers.

scholarly journals Waist circumference and waist circumference to height ratios of Kaingáng indigenous adolescents from the State of Rio Grande do Sul, Brazil

2012 ◽  
Vol 28 (11) ◽  
pp. 2053-2062 ◽  
Author(s):  
Teresa Gontijo de Castro ◽  
Laura A. Barufaldi ◽  
Michael Maia Schlüssel ◽  
Wolney Lisboa Conde ◽  
Maurício Soares Leite ◽  
...  
Keyword(s):  
Waist Circumference ◽  
Correlation Coefficients ◽  
Cross Sectional Study ◽  
Rio Grande Do Sul ◽  
Sectional Study ◽  
Cross Sectional ◽  
School Based ◽  
High Prevalence ◽  
Z Scores ◽  
Indigenous Adolescents

The aim of this study was to describe the distribution of waist circumference (WC) and WC to height (WCTH) values among Kaingáng indigenous adolescents in order to estimate the prevalence of high WCTH values and evaluate the correlation between WC and WCTH and body mass index (BMI)-for-age. A total of 1,803 indigenous adolescents were evaluated using a school-based cross-sectional study. WCTH values > 0.5 were considered high. Higher mean WC and WCTH values were observed for girls in all age categories. WCTH values > 0.5 were observed in 25.68% of the overall sample of adolescents. Mean WC and WCTH values were significantly higher for adolescents with BMI/age z-scores > 2 than for those with normal z-scores. The correlation coefficients of WC and WCTH for BMI/age were r = 0.68 and 0.76, respectively, for boys, and r = 0.79 and 0.80, respectively, for girls. This study highlights elevated mean WC and WCTH values and high prevalence of abdominal obesity among Kaingáng indigenous adolescents.

scholarly journals Age and body mass index affect fit of spirometry GLI references in schoolchildren

2021 ◽  
Author(s):  
Rebeca Mozun ◽  
Cristina Ardura-Garcia ◽  
Eva S. L. Pedersen ◽  
Jakob Usemann ◽  
Florian Singer ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Lung Function ◽  
Body Mass ◽  
Clinical Decision Making ◽  
Clinical Care ◽  
Normal Weight ◽  
Linear Regression Models ◽  
Cross Sectional ◽  
Mean Values ◽  
Z Scores

AbstractBackgroundReferences from the Global Lung Function Initiative (GLI) are widely used to interpret children’s spirometry results. We assessed fit for healthy schoolchildren.MethodsLuftiBus in the school (LUIS) is a population-based cross-sectional study done from 2013-2016 in the canton of Zurich, Switzerland. Parents and children aged 6-17 years answered questionnaires about respiratory symptoms and lifestyle. Children underwent spirometry in a mobile lung function lab. We calculated GLI-based z-scores for FEV1, FVC, FEV1/FVC, and FEF25-75 for healthy White participants. We defined appropriate fit to GLI references by mean values ±0.5 z-scores. We assessed if fit varied by age, body mass index, height, and sex using linear regression models.ResultsWe analysed data from 2036 children with valid FEV1 measurements of which 1762 also had valid FVC measurements. The median age was 12.2 years. Fit was appropriate for children aged 6-11 years for all indices. In adolescents aged 12-17 years, fit was appropriate for FEV1/FVC (mean: -0.09; SD: 1.02) z-scores, but not for FEV1 (mean: -0.62; SD: 0.98), FVC (mean: -0.60; SD: 0.98), and FEF25-75 (mean: -0.54; SD: 1.02). FEV1, FVC, and FEF25-75 z-scores fitted better in children considered overweight (means: -0.25, -0.13, -0.38) than normal weight (means: -0.55, -0.50, -0.55; p-trend: <0.001, 0.014, <0.001). FEV1, FVC, and FEF25-75 z-scores depended on both age and height (p interaction: 0.034, 0.019, <0.01).ConclusionGLI-based FEV1, FVC, and FEF25-75 z-scores do not fit White Swiss adolescents well. This should be considered when using reference equations for clinical decision making, research and international comparison.Take home messageOur study suggests GLI-based FEV1, FVC, and FEF25-75 z-scores over detect abnormal lung function in Swiss adolescents, and more so among slimmer adolescents, which has important implications for clinical care, research, and international comparisons.

scholarly journals Serum 25-hydroxyvitamin D levels and lung function in adults with asthma: the HUNT Study

2014 ◽  
Vol 45 (4) ◽  
pp. 1019-1026 ◽  
Author(s):  
Tricia L. Larose ◽  
Arnulf Langhammer ◽  
Yue Chen ◽  
Carlos A. Camargo ◽  
Pål Romundstad ◽  
...  
Keyword(s):  
Allergic Rhinitis ◽  
Lung Function ◽  
Vital Capacity ◽  
Forced Expiratory Volume ◽  
Health Study ◽  
Linear Regression Models ◽  
Cross Sectional ◽  
Hydroxyvitamin D ◽  
25 Hydroxyvitamin D ◽  
Hunt Study

The association between vitamin D status and lung function in adults with asthma remains unclear.We studied this cross-sectional association and possible modification by sex and allergic rhinitis in 760 adults (aged 19–55 years) with self-reported asthma in the Nord-Trøndelag Health Study. Serum 25-hydroxyvitamin D (25(OH)D) level <50 nmol·L−1was considered deficient. Lung function measurements included forced expiratory volume in 1 s (FEV1) % predicted, forced vital capacity (FVC) % predicted and FEV1/FVC ratio. Multiple linear regression models were used to estimate adjusted regression coefficients (β) and 95% confidence intervals.44% of asthma adults had serum 25(OH)D levels <50 nmol·L−1. Its associations with lung function measures seemed to be modified by sex and allergic rhinitis (p<0.03 for three-way interaction term). Overall, a serum 25(OH)D level <50 nmol·L−1was not associated with lung function measurements in subjects with allergic rhinitis in this asthma cohort. In men with asthma but without allergic rhinitis, however, a serum 25(OH)D level <50 nmol·L−1was significantly associated with lower FEV1/FVC ratio (β=−8.60%; 95% CI: −16.95%– −0.25%).Low serum 25(OH)D level was not associated with airway obstruction in most asthma adults with the exception of men with asthma but without allergic rhinitis.

scholarly journals Socioeconomic status and pulmonary function, transition from childhood to adulthood: cross-sectional results from the polish part of the HAPIEE study

BMJ Open ◽  
2019 ◽  
Vol 9 (1) ◽  
pp. e022638 ◽  
Author(s):  
Maciej Polak ◽  
Krystyna Szafraniec ◽  
Magdalena Kozela ◽  
Renata Wolfshaut-Wolak ◽  
Martin Bobak ◽  
...  
Keyword(s):  
Socioeconomic Status ◽  
Lung Function ◽  
Pulmonary Function ◽  
Life Course ◽  
Social Mobility ◽  
Cross Sectional Study ◽  
Forced Expiratory Volume ◽  
Low Ses ◽  
Cross Sectional ◽  
Downward Social Mobility

ObjectivePrevious studies have reported inverse associations between socioeconomic status (SES) and lung function, but less is known about whether pulmonary function is affected by SES changes. We aimed to describe the relationship of changes of SES between childhood and adulthood with pulmonary function.DesignCross-sectional study.ParticipantsThe study sample included 4104 men and women, aged 45–69 years, residents of Krakow, participating in the Polish part of the Health, Alcohol and Psychosocial Factors in Eastern Europe Project.Main outcomeForced expiratory volume (FEV1) and forced vital capacity (FVC) were assessed by the standardised spirometry procedure. Participants were classified into three categories of SES (low, moderate or high) based on information on parent’s education, housing standard during childhood, own education, employment status, household amenities and financial status.ResultsThe adjusted difference in mean FVC between persons with low and high adulthood SES was 100 mL (p=0.005) in men and 100 mL (p<0.001) in women; the differences in mean FEV1were 103 mL (p<0.001) and 80 mL (p<0.001), respectively. Upward social mobility and moderate or high SES at both childhood and adulthood were related to significantly higher FEV1and FVC compared with low SES at both childhood and adulthood or downward social mobility.ConclusionsLow SES over a life course was associated with the lowest lung function. Downward social mobility was associated with a poorer pulmonary function, while upward mobility or life course and moderate or high SES were associated with a better pulmonary function.

scholarly journals Predictors of impaired pulmonary function in people living with HIV in an urban African setting

2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Sarah E. Van Riel ◽  
Kerstin Klipstein-Grobusch ◽  
Roos E. Barth ◽  
Diederick E. Grobbee ◽  
Charles Feldman ◽  
...  
Keyword(s):  
Lung Function ◽  
Characteristic Curve ◽  
Cross Sectional Study ◽  
Forced Expiratory Volume ◽  
Normal Lung ◽  
People Living With Hiv ◽  
Cross Sectional ◽  
Increased Risk ◽  
Impaired Lung Function ◽  
History Of

Background: Studies have associated HIV with an increased risk of obstructive lung disease (OLD).Objectives: We aimed to identify the predictive factors for impaired lung function in an urban, African, HIV-positive population.Method: A cross-sectional study was performed in Johannesburg, South Africa, from July 2016 to November 2017. A questionnaire was administered and pre- and post-bronchodilator spirometry conducted. The predictors investigated included age, sex, antiretroviral treatment (ART) duration, body mass index, history of tuberculosis (TB) or pneumonia, occupational exposure, environmental exposure, smoking and symptoms of OLD (cough, wheeze, mucus and dyspnoea). Impaired lung function was defined as a forced expiratory volume in 1 second/forced vital capacity (FEV1/FVC) ratio of 0.70, or below the 20th percentile of normal.Results: The 98 ART-naïve participants (mean age = 34.0, standard deviation [s.d.] = 8.2), 85 participants on first-line ART (mean age = 36.9, s.d. = 6.6) and 189 participants on second-line ART (mean age = 43.5, s.d. = 7.9) were predominantly female (65.6%). Of the participants, 64 (17.2%) had impaired lung function and 308 had normal lung function. Linear regression identified age (β = –0.003, P 0.01), male sex (β = –0.016, P = 0.03) and history of TB or pneumonia (β = –0.024, P 0.01) as independent predictors of a lower FEV1/FVC ratio. Following logistic regression, only a history of TB or pneumonia (odds ratio = 2.58, 95% confidence interval = 1.47–4.52) was significantly related to impaired lung function (area under the receiver operating characteristic curve = 0.64).Conclusion: Our data show that a history of TB or pneumonia predicts impaired lung function. In order to improve timely access to spirometry, clinicians should be alert to the possibility of impaired lung function in people with a history of TB or pneumonia.

scholarly journals Chronic Respiratory Symptoms and Lung Function of Farmer and Breeder in UTU Village, Tabanan, Bali

2020 ◽  
Vol 8 (B) ◽  
pp. 709-715
Author(s):  
Ni Luh Putu Eka Arisanti ◽  
Ni Putu Ayu Widiasari ◽  
Ida Bagus Ngurah Rai
Keyword(s):  
Lung Function ◽  
Respiratory Symptoms ◽  
Vital Capacity ◽  
Cross Sectional Study ◽  
Forced Expiratory Volume ◽  
Smoking History ◽  
Sectional Study ◽  
Lung Function Decline ◽  
Cross Sectional ◽  
Passive Smoker

AIM: The objective of the study was to determine chronic respiratory symptoms and lung function of farmers. METHODS: The study was conducted in Utu Village, Tabanan, Bali with 84 subjects. This research was observational analytic cross sectional study. RESULTS: Three dominant chronic respiratory symptoms in farmers were coughing (15.1%), dyspnea (13.1%), and phlegm (13.1%). Average values of forced expiratory volume in 1 s (FEV1), forced vital capacity (FVC), and FEV1/FVC were 83.75 ± 34.42, respectively, 81.62 ± 34.30 and 104.90 ± 13.90, respectively. Cough was dominant experiencing by smokers (p = 0.008). Mean of FEV1% prediction and FVC% prediction value was lower in passive smoker group than no smoker group (p = 0.005 and p = 0.03). CONCLUSION: Occupational exposure while farming and raising livestock can cause chronic respiratory symptom and lung function decline in farmers and can be influenced by smoking history and secondhand smoke exposure.

scholarly journals Normal Sudanese Spirometeric Values for Police Men

2020 ◽  
Author(s):  
Barakat Mohazab Bakhit ◽  
Omer Abd_elaziz Musa ◽  
Mohanad Hassan Malla
Keyword(s):  
Lung Function ◽  
Reference Values ◽  
Police Officers ◽  
Reference Value ◽  
Cross Sectional Study ◽  
Forced Expiratory Volume ◽  
Anthropometric Measurements ◽  
Regression Equations ◽  
Continuous Training ◽  
Cross Sectional

Abstract BackgroundSpirometric values for police officers in the police hospital, Khartoum, Sudan were observed to show higher values than predicted.1 Reference values are important for diagnosis of asthma and chronic bronchitisMethodsFor deriving a new reference value for adult police men, a cross- sectional study was performed on 161 adult male police officers, aged 20–50 years in (June- December 2012) in Khartoum state in different police units. Data were obtained through a questionnaire, pulmonary function testing and taking anthropometric measurements, forced vital capacity (FVC), forced expiratory volume in first second (FEV1) and peak expiratory flow rate (PEFR) were measured using a microplus spirometer and a peak flow meter. Lung function values and anthropometric measurements were correlated and regression equations were derivedResultsAdult police males had a significantly higher FVC, FEV1and PEFR [3.96 ± 0.56 L , 3.61 ± 0.52 L and 564.1 ± 70.4 L/min respectively] than those of normal adult Sudanese males [3.68 ± 0.22 L , 3.35 ± 0.23 L and 505.9 ± 19.1L/min respectively]. A positive correlation was found between lung function and height and a negative correlation with age. Regression equations of normal predicted values were derived for police officer FVC (L) [0.027 X (cm) – 0.039 X A (years) +0.345], FEV1 (L) [0.0264 X (cm) – 0.036 X A (years) +0.0105] and PEFR (L/min) [1.599 X (cm) – 4.207 X A (years) + 329.349.Conclusionsit seems that the continuous training of police officers produced higher lung volumes and a separate reference values tables should be used for them

scholarly journals Lung Function and Respiratory Symptoms of Petrol Station Attendants in Central and North Jakarta and Its Contributing Factors

2020 ◽  
Vol 1 (1) ◽  
pp. 46-60
Author(s):  
Putri Suci Ramadhany ◽  
Faisal Yunus ◽  
Agus Dwi Susanto
Keyword(s):  
Lung Function ◽  
Respiratory Symptoms ◽  
Motor Vehicle ◽  
Sampling Technique ◽  
Cross Sectional Study ◽  
Forced Expiratory Volume ◽  
Contributing Factors ◽  
Cross Sectional ◽  
Petrol Station ◽  
Big City

Background: To satisfy growing needs of petrol consumption in big city many new petrol stations has been built. Petrol station attendant is considered to have high risk exposure to dangerous pollutant from motor vehicle emission and petrol fumes, especially while filling up petrol tanks. Combination of those exhaust and petrol fumes is suspected to cause the reduction of lung function. Methods: This research is a cross sectional study in petrol station in Central Jakarta and North Jakarta region between August 2017 and February 2018. A total of 97 petrol station attendants were taken in this research using consecutive sampling technique. The subjects were interviewed with questionnaires, spirometry and chest radiograph. Measurements of sulfur dioxide (SO2), nitrogen dioxide (NO2), carbon monoxide (CO), ozone (O3), particulate matter 2,5 (PM 2,5) and steam gasoline (benzene) concentrations were performed at the study sites. Results: In this study, 56.7% normal spirometry results, 42.3% abnormalities in the form of restriction, 1% obstruction and none of which experienced mixed disorders of restriction and obstruction. Most subjects (84.6%) did not experience respiratory complaints, 10.3% had a dry cough and 5.1% complained of cough with phlegm. There was a statistically significant association between peak expiratory flow and duration of work (p=0.011), but no significant association with other parameters such as forced vital capacity (FVC), %FVC, forced expiratory volume in the first second (FEV1), %FEV1 and the ratio of FEV1/FVC. Conclusion: Prevalence of lung function abnormalities of petrol station attendant is 43,3% and respiratory symptoms at 15,4% subject.

scholarly journals pQCT bone geometry and strength: population epidemiology and concordance in Australian children aged 11–12 years and their parents

BMJ Open ◽  
2019 ◽  
Vol 9 (Suppl 3) ◽  
pp. 63-74 ◽  
Author(s):  
Jennifer Vlok ◽  
Peter J Simm ◽  
Kate Lycett ◽  
Susan A Clifford ◽  
Anneke C Grobler ◽  
...  
Keyword(s):  
Correlation Coefficients ◽  
Bone Geometry ◽  
Population Based ◽  
Cross Sectional Study ◽  
Linear Regression Models ◽  
Quantitative Ct ◽  
Cross Sectional ◽  
Total Cross Sectional Area ◽  
Cortical Density ◽  
Parent Child

ObjectivesTo describe the epidemiology and concordance of bone health in a population-based sample of Australian parent-child dyads at child age 11–12 years.DesignPopulation-based cross-sectional study (the Child Health CheckPoint) nested between waves 6 and 7 of the Longitudinal Study of Australian Children (LSAC).SettingAssessment centres in seven cities around Australia, February 2015–March 2016.Participants: of all participating CheckPoint families (n=1874), bone data were available for 1222 dyads (1271 children, 50% girls; 1250 parents, 86% mothers).Outcome measuresPeripheral quantitative CT (pQCT) of the non-dominant leg scanned at the 4% (distal) and 66% (mid-calf) tibial sites. Stratec XCT 2000 software generated estimates of bone density, geometry and polar stress-strain index.Parent-child concordance were assessed using Pearson’s correlation coefficients and multivariable linear regression models. Percentiles were determined using survey weights. Survey weights and methods accounted for LSAC’s complex sampling, stratification and clustering within postcodes.ResultsConcordances were greater for the geometric pQCT parameters (periosteal circumference 0.38, 95% CI 0.33 to 0.43; endosteal circumference 0.42, 95% CI 0.37 to 0.47; total cross-sectional area 0.37, 95% CI 0.32 to 0.42) than density (cortical density 0.25, 95% CI 0.19 to 0.30). Mother-child and father-child values were similar. Relationships attenuated only slightly on adjustment for age, sex and body mass index. Percentiles and concordance are presented for the whole sample and by sex.ConclusionsThere is strong parent-child concordance in bone geometry and, to a lesser extent, density even before the period of peak adolescent bone deposition. This geometrical concordance suggests that future intergenerational bone studies could consider using pQCT rather than the more commonly used dual X-ray absorptiometry (DXA).

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