scholarly journals The Influence of Dentine on the pH of Calcium Hydroxide, Chlorhexidine Gel, and Experimental Bioactive Glass-Based Root Canal Medicament

2015 ◽  
Vol 2015 ◽  
pp. 1-5 ◽  
Author(s):  
Ceci Nunes Carvalho ◽  
Laila Gonzales Freire ◽  
Alexandre Pinheiro Lima de Carvalho ◽  
Evandro Luiz Siqueira ◽  
José Bauer ◽  
...  

Objectives. To evaluate the influence of dentine on the pH of different medications in standardized simulated canals.Materials and Methods. Forty resin blocks were divided into groups with and without dentine powder, as follows: 2% chlorhexidine gel; 2% chlorhexidine gel associated with calcium hydroxide PA; calcium hydroxide PA delivered in propylene glycol 600; and NPG delivered in distilled water. The dentine powder was obtained from the root dentine of bovine teeth and added to the medications. The simulated canals were placed in containers with 1.5 mL of deionized water and pH was monitored in multiple intervals, up to 30 days. The mean pH values were calculated and submitted to statistical analysis using paired Student’st-test and ANOVA complemented by the Tukey test (p<0.05).Results. There was no statistical difference between the groups with and without dentine powder (p>0.05). The pH values of calcium hydroxide were significantly higher than those of NPG in the first 24 hours (p<0.05). After 7 days, both behaved in a similar manner.Conclusion. The addition of dentine powder to the medications evaluated did not alter the pH of the external solution in any of the time points tested.

2018 ◽  
Vol 47 (4) ◽  
pp. 205-209
Author(s):  
Kamila de Figueiredo PEREIRA ◽  
Rosymere Freitas de Sousa CRUVINEL ◽  
Andrea Abi Rached DANTAS ◽  
Milton Carlos KUGA

Abstract Introduction Cavity liners based calcium hydroxide present low strength and high solubility that is consider a disadvantage. In order to enhance these properties it was developed a light-cured cavity liner based calcium hydroxide containing resin. Objective The purpose of this study was to evaluate the pH and calcium release of light-cured cavity liners. Material and method There were prepared specimens (n=10) with the Ultra-Blend ® plus, Biocal® (light cured cements) and Hydro C® (control). The samples were stored in 10 mL of distilled water and maintained at 37 °C. After 24 hours, 7, and 14 days, there were analyzed pH and the release of calcium levels. The data were statistically analyzed by ANOVA and Tukey test (α = 0.05). Result The results of pH showed Hydro C > Ultra-Blend plus > Biocal. Biocal presented worst calcium release. Conclusion Light-cured materials present lower calcium release and alteration in pH values.


2009 ◽  
Vol 20 (5) ◽  
pp. 382-388 ◽  
Author(s):  
Morgana Eli Vianna ◽  
Danila M. Zilio ◽  
Caio Cezar Randi Ferraz ◽  
Alexandre Augusto Zaia ◽  
Francisco José de Souza-Filho ◽  
...  

The purpose of this in vitro study was to measure the concentration of hydrogen ions (pH) of calcium hydroxide [(Ca(OH)2] pastes combined with different vehicles over 7 periods of time. The Ca(OH)2 was manipulated with the following vehicles: i: sterile water; ii: iodoform plus sterile water; iii: local anesthetics (Lydocaine 2% with 1: 100,000 epinephrine); iv: polyethyleneglycol; v: glycerin; vi: 2.0% chlorhexidine gel; vii: camphorated paramonochlorophenol (CMCP); viii: (CMCP) + glycerin; and ix: polyethyleneglycol plus CMCP. The pastes were made on a glass plate to toothpaste consistency and the pH was measured at the following times: 5 min, 1, 24, 48 h; 7, 14 and 28 days. The data were statistically analyzed (Kruskal-Wallis at p<0.05). At 5 min, 1 and 24 h, the pH of all tested pastes ranged from 13.05 to 11.16. At 48 h and 7 days the pH of all tested pastes ranged from 11.66 to 8.92. At 14 and 28 days almost all pastes had pH means lower than 10. In conclusion, the mean pH of all tested calcium hydroxide pastes decreased with the time. Pastes made with aqueous vehicles (especially with sterile water), followed by oily vehicles (especially with CMCP + glycerin), held the highest pH means over the periods of time tested.


2013 ◽  
Vol 1 (4) ◽  
pp. 344
Author(s):  
Hemanoely Marins-de-Azevedo ◽  
Rodrigo Vargas Conti Montenario ◽  
Mariana Pires Crespo ◽  
Milton Carlos Kuga ◽  
Camila Almeida Nascimento

This study evaluated the effect of the addition of 5% calcium chlorite (CaCl2) on pH values in calcium hydroxide pastes (CH), with or without 2% chlorhexidine digluconate (CHX) used as vehicle, in several periods analysis. Polyethylene tubes were filled with CH mixed with water (G1), 2% CHX solution (G2) or gel (G3), or CHX solution  or gel with 5% CaCl2 (G4 and G5, respectively). All tubes were individually immersed in distilled water. After 12, 24 hours, 7, 14 and 28 days, pH value was evaluated directly in water which the tubes were stored. Data were submitted to ANOVA and Tukey tests (α=0.05). In 24 hs and 14 days, pH values were similar to all groups. In 12 hs, the G1 presented lower pH value than other groups except to G4 (p < 0.05), and G4 presented lower pH value than G5 (p < 0.05). In 7 days, G1 presented lower pH value than G4 and G5 (p < 0.05). In 28 days, G1 and G5 presented lower pH values than G2 and G4 (p < 0.05) and among other groups there are no statistical differences (p > 0.05). The pH values increased in long-term analysis to all CH pastes. The association of 5% calcium chloride with 2% CHX solution as vehicle of CH paste provided a pH value increase in relation to CH mixed with distilled water. The CHX gel interfered negatively on pH value in comparison to CHX solution when mixed with CaCl2.


2009 ◽  
Vol 52 (4) ◽  
pp. 855-862 ◽  
Author(s):  
Lucí Regina Panka Archegas ◽  
Rodrigo Nunes Rached ◽  
Sérgio Aparecido Ignacio ◽  
Eliane Carvalho de Vasconcelos ◽  
Débora Toledo Ramos ◽  
...  

The aim of this study was to detect and quantify the main residual monomers released from composites, using high performance liquid chromatography (HPLC). Discs were made with dental composites (Herculite XRV, Tetric Ceram and Filtek Z250) and immersed in deionized water at 37ºC for 28 days, with water changes in 1, 7, 14 and 21 days. The mean concentration of residual monomers were subject to the Kruskal-Wallis test (p<0.05). Tetric Ceram exhibited significantly higher concentrations of leached monomers. Bis-GMA was the monomer released in lower concentrations for all the materials. There was no statistical difference between the amounts of TEGDMA and UDMA. Most of the monomers demonstrated maximal concentration at the 7-day period. The HPLC analysis identified Bis-GMA, TEGDMA and UDMA in detectable quantities for all the tested composites.


2016 ◽  
Vol 15 (1) ◽  
pp. 75
Author(s):  
Maria Mercês Aquino Gouveia Farias ◽  
Magatha Marquetti Lazzaris de Oliveira ◽  
Beatriz Helena Eger Schmitt ◽  
Eliane Garcia da Silveira ◽  
Silvana Marchiori de Araújo

Aim: To compare the acidity of sugar-free hard candies dissolved in water and artificial saliva. Methods: Sugar-free Flopi Florestal hard candies (grape, strawberry, cherry, orange, ginger, lemon balm, fennel) were selected and grouped in 2 groups: G-1 (candies dissolved in distilled water) and G-2 (candies dissolved in artificial saliva). Candies were triturated with a porcelain pestle, yielding two samples of 20 g. Samples were dissolved in 120 mL distilled water (G-1) and 120 mL artificial saliva (20 mM NaHCO3, 3 mM NaH2PO4.H2O and 1 mM CaCl2.2H2O) (G-2), obtaining three samples of 30 mL for each of the flavors and groups. pH was measured using potentiometer and combined glass electrode. Titratable acidity was evaluated by adding 100 μL 1M NaOH aliquots until reaching pH 5.5. For statistical analysis, analysis of variance (ANOVA) was used. Means were compared by the Tukey test at 5% significance level (p<0.05) Results: All flavors of G-1 showed pH values below 5.5. Comparison of groups in the same flavor showed a significant increase in pH in flavors of G-2. Comparison of the titratable acidity between G-1 and G-2, showed that fruit flavors were significantly different from each other, with reduced acidity in G-2. Conclusions: All evaluated candies are acid, and dilution in artificial saliva raised their pH and lowered their titratable acidity, reducing their erosive potential.


2013 ◽  
Vol 1 (3) ◽  
pp. 199
Author(s):  
Adriana Maria Jorge Dal'acqua Silva ◽  
Joice González Guerrero ◽  
Luciana De Rezende Pinto ◽  
Ricardo Martins Carvalho ◽  
Vinicius Carvalho Porto

This study evaluated the changes in surface roughness and color of materials employed in the fabrication of prosthetic bases after immersion in disinfectants. Sixty specimens were fabricated using a round matrix; half of the specimens were fabricated with a heat-cured composite resin, and the other half with a light-cured composite resin. After polishing, the specimens were stored in distilled water at 37ºC from 48 to 52 hours, and then submitted to initial tests of surface roughness and color. The specimens were randomly divided into three groups and immersed in the following chemicals: G1 (1% sodium hypochlorite for 10 minutes), G2 (5.25% sodium hypochlorite for 5 minutes) and G3 (2% acidic glutaraldehyde for 10 minutes). The surface roughness and color tests were once again performed and the specimens were then stored in deionized water at 37ºC for 6 days. On the seventh day, the immersion was repeated; this procedure was performed at every 7 days during 1 month and the tests were repeated after the fourth week. The results were submitted to three-way analysis of variance (ANOVA) and to the Tukey test. Within the same groups of specimens, statistically significant differences were only observed for the light-cured resin, which presented slight changes after exposure to 5.25% sodium hypochlorite and 2% glutaraldehyde for the interval ΔE2, which indicates differences in reading values between immersion after 30-day storage and the first immersion in the disinfectants.


2017 ◽  
Vol 10 (4) ◽  
pp. 324-329
Author(s):  
Alok Avinash ◽  
Harsha Munot ◽  
Rashmi Baranwal ◽  
Vijay Duggi ◽  
Alok Dubey ◽  
...  

ABSTRACT Introduction One of the most important factors for successful endodontic therapy is root canal cleaning. The difficulty involved in eliminating microorganisms, as well as their residual presence, warrants the use of root canal dressings after biomechanical preparation. Aim The aim of the study was to compare the diffusion ability between nonalcoholic calcium hydroxide—propolis paste, calcium hydroxide—saline paste, and calcium hydroxide—propylene glycol paste. Materials and methods For this proposed study, single-rooted extracted permanent teeth were randomly divided into three groups to fill the canals: group I: Calcium hydroxide—propylene glycol paste, group II: Calcium hydroxide—saline paste, and group III: Calcium hydroxide—propolis paste. After complete filing of the root canal, the pH values of the solutions in the flasks are measured at an interval of 3, 24, 72, 168 hours. Results After 168-hour interval, it was noticed that the mean pH obtained by calcium hydroxide—propolis paste was 10.54 (± 0.38), which was greater than calcium hydroxide—propylene glycol paste 9.70 (± 0.45) and calcium hydroxide—saline paste 9.16 (± 0.30) consecutively. Conclusion The nonalcoholic calcium hydroxide—propolis paste used during the study was able to diffuse through the dentinal tubules. Thus, it can be used as a vehicle for calcium hydroxide. How to cite this article Baranwal R, Duggi V, Avinash A, Dubey A, Pagaria S, Munot H. Propolis: A Smart Supplement for an Intracanal Medicament. Int J Clin Pediatr Dent 2017;10(4):324-329.


2008 ◽  
Vol 19 (1) ◽  
pp. 28-33 ◽  
Author(s):  
Francisco José de Souza-Filho ◽  
Adriana de Jesus Soares ◽  
Morgana Eli Vianna ◽  
Alexandre Augusto Zaia ◽  
Caio Cezar Randi Ferraz ◽  
...  

The purposes of this study were to evaluate the effectiveness of 2% chlorhexidine (CHX) gluconate gel, calcium hydroxide [Ca(OH)2] and their combination with iodoform and zinc oxide powder as intracanal medications against select microorganisms, and to measure the pH changes caused by these medications. Antimicrobial activity was determined by the agar diffusion method. The zones of growth inhibition were measured and the results were analyzed statistically by Kruskal-Wallis test (p<0.05). The pH of the pastes was measured right after preparation, after 24 h and 1 week later. The largest mean zones of microbial inhibition were produced by 2% CHX gel, followed by Ca(OH)2 + 2% CHX gel + iodoform, Ca(OH)2 + 2% CHX gel, Ca(OH)2 + 2% CHX gel + zinc oxide, and Ca(OH)2 + water. The mean pH of all medications stayed above 12.0 during the whole experiment, except for CHX gel (pH=7.0). The results of this study showed that all medications had antimicrobial activity, but the most effective against the tested microorganisms were 2% CHX gel, followed by its combination with Ca(OH)2 and iodoform.


1965 ◽  
Vol 49 (1) ◽  
pp. 1-16 ◽  
Author(s):  
M. Apostolakis

ABSTRACT A method for the extraction of prolactin from human pituitary glands is described. It is based on acetone drying, distilled water extraction, acetone and isoelectric precipitation. Two main products are obtained: Fraction R8 with a mean prolactin activity of 12.2 IU/mg and fraction U8 with a mean prolactin activity of 8.6 IU/mg. The former fraction does not contain any significant gonadotrophin activity and the latter contains on an average 50 HMG U/mg. In both cases contamination with ACTH and MSH is minimal. The growth hormone activity of both these fractions is low. It is postulated that in man too, prolactin and growth hormone are two distinct hormones. A total of 1250 human pituitary glands have been processed by this method. The mean prolactin content per pituitary gland has been found to be 73 IU.


Author(s):  
Syoof Khowman Alramahy ◽  
Akram Hadi Hamza

This study was carried out to study of some immunological aspects among the pulmonary Tuberculosis patients infected with causative agent, Mycobacterium tuberculosis. A Total of 200 sputum samples were collected from patients attending the consultant Clinic for Chest and Respiratory disease center, Diwaniya. Control group (No=15) also included. According to acid fast stain of sputum, the patients were classified as positive (No=91,45.5%) and negative (No=109,54.5, Lowenstein Jensen medium used for the cultivation of samples, on which 70% of sputum samples where positive culture for this microorganism. The grown microorganism were identified as M. tuberculosis, based on positive A.F.B, Niacin producers ,negative for catlase at 68c. The mean IgG level was l184.053±76.684 mg/100 ml in tuberculosis group compared with 1016.533 ± 44.882 mg/100ml in control group, rendering the statistical difference significant. For IgA and IgM levels, they were at mean of 315.880±38.552 mg/100 ml and 119.527±8.464 mg/100 ml in control group compared with 396.358±38.776 mg/100 ml and 134.207±11.696 mg/100 ml in patients group respectively with significant difference


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