scholarly journals Analysis of Mortality and Survival Rate of Liver Cancer in Zhejiang Province in China: A General Population-Based Study

2019 ◽  
Vol 2019 ◽  
pp. 1-6
Author(s):  
Fang-Rong Fei ◽  
Ru-Ying Hu ◽  
Wei-Wei Gong ◽  
Jin Pan ◽  
Meng Wang

Background. Few accurate up-to-date studies provide liver cancer mortality and survival information in Zhejiang province. This research aimed to depict the mortality and survival of liver cancer in Zhejiang province in China during 2005-2010. Methods. The data were collected from the Zhejiang Chronic Disease Surveillance Information and Management System, and the mortality rates of liver cancer were calculated by gender, age, and areas. Chinese population census in 2000 and Segi’s world population were used for age-standardized mortality rate. The observed and relative survival rates of liver cancer patients were analyzed. Results. The crude mortality rate of liver cancer was 32.11/105. The age-standardized mortality rate was 17.39/105 and 23.07/105 by Chinese population (ASIRC) and Segi’s world population (ASIRW), respectively. The crude liver cancer mortality rate and age-standardized rate in urban areas were lower than those of rural areas. The overall 1-, 3-, and 5-year observed survival (OS) rates of liver cancer patients were 38.61%, 21.65%, and 16.83%, respectively. The 1-, 3-, and 5-year relative survival (RS) rates of liver cancer patients were 39.49%, 23.27%, and 19.09%, respectively. Survival rate decreased obviously within 1 to 5 years and then leveled off. It was shown that the male overall survival rate was higher than the female one and the difference was statistically significant (P<0.05). Conclusions. Both lower mortality and better survival rates were observed in urban areas, compared to rural areas. Relevant parties including government, public resource, and propaganda department should devote enough attention to rural areas.

2013 ◽  
Vol 19 (4) ◽  
pp. 439-444
Author(s):  
Giedrė Smailytė ◽  
Robertas Adomaitis ◽  
Karolis Ulinskas ◽  
Birutė Aleknavičienė

Background. The aim of this study was to evaluate changes in the survival of prostate cancer patients during the 12-year period and to analyze differences in survival by period of diagnosis, stage of disease, age and place of residence. Materials and methods. All newly diagnosed cases of prostate cancer (ICD-10, C61) in men were identified in the Lithuanian Cancer Registry for the period 1994–2005. Five-year relative survival estimates were computed with the Hakulinen method using the STATA software. Five-year relative survival estimates were calculated for three different periods of time when prostate cancer was diagnosed (1994–1997, 1998–2001 and 2002–2005), by age (15–59, 60–74, and 75–99), stage at diagnosis (I, II, III, IV, unknown) and place of residence (cities and towns or rural areas). Results. The survival of prostate cancer patients in Lithuania has dramatically increased. Five-year relative survival in the period 1994–1997 was 46.92% and in the period 2002–2005 it reached 86.49%. Medium age prostate cancer patients (60–74 years) compared to younger and older patients had better survival rates. Increasing survival was observed for all stages of disease. Lower five-year relative survival rate of prostate cancer patients was reported for men from villages or other rural areas compared to patients from cities and towns in all periods under study. Conclusions. The five-year survival rate of patients with prostate cancer has increased from 46.92% (95% CI 44.12–49.74) in 1994–1997 to 86.49% (95% CI 84.73–88.22) in 2002–2005 in Lithuania. The study identified survival differences by age and place of residence. Issues, such as access to care, quality of medical care, must be made equally available and accessible for the whole population with special attention to older men and men living in rural areas.


2021 ◽  
Author(s):  
Vakhtang M. Merabishvili ◽  
Elvira N. Merabishvili ◽  
Alexander M. Shcherbakov ◽  
Alexander B. Vasiliev ◽  
Alexey F. Barsukov ◽  
...  

Malignant neoplasms of the tongue occupy 0.55% in the general structure of the cancer incidence in Russian population. No information on other parameters (the number of deaths, mortality of patients, their distribution by stages of the disease and other analytical indicators) is provided in the official reporting. The opportunity appeared only with the development of Population-based Cancer Registries (PCR) system, but this wealth of material is not used for the official reporting. Tongue cancer is a visual localization with a high mortality rate, which requires special attention. The study was conducted to investigate the state of Russian Oncology Service for tongue cancer patients with the calculations of one-year mortality rate, annual mortality rate, median survival, 1,3,5-year observed and relative survival rates, first time in Russia, at the level of the newly created Population-based Cancer Registry of the Federal District. In Russia, there has been little research on the analysis of the cancer survival rate at the population level. We have been conducting developments for all malignant tumors localizations since 2000 based on the St. Petersburg PCR database. The level of 5-year observed and relative survival rates for tongue cancer patients in Russia (St. Petersburg and the NWFD RF) has been found to be significantly lower than the EU average (Eurocare-4). To carry out this study, 5188 observations from the NWFD RF PCR database were selected. It has been established that during 4 periods of observation, the mortality rate for tongue cancer patients during the first year of observation in the NWFD RF has decreased under the C01 rubric (cancer of the base of the tongue) from 58.5 to 45.8%; and under the C02 rubric (malignant neoplasm of other and unspecified parts of tongue) from 54.5 to 42.7%. The five-year survival rate for tongue cancer patients has increased by 23.3%.


2020 ◽  
Vol 9 (12) ◽  
pp. 4038
Author(s):  
Audrius Dulskas ◽  
Vytautas Gaizauskas ◽  
Inga Kildusiene ◽  
Narimantas Evaldas Samalavicius ◽  
Giedre Smailyte

Purpose: In this study, we analyzed the mortality and survival of colorectal cancer patients in Lithuania. Methods: This was a national cohort study. Population-based data from the Lithuanian Cancer Registry and period analyses were collected. Overall, 20,980 colorectal cancer patients were included. We examined the changes in colorectal cancer mortality and survival rates between 1998 and 2012 according to cancer anatomical sub-sites and stages. We calculated the 5-year relative survival estimates using period analysis. Results: Overall, 20,980 colorectal cancer cases reported from 1998 to 2012 were included in the study. The total number of newly diagnosed colorectal cancers increased from 1998–2002 to 2008–2012 by 12.1%. The highest number of colorectal cancers was localized and increased from 33.9% to 42.0%. The number of cancers with regional metastases and advanced cancers decreased by 11.1% and 15.5%, respectively. An increased number of new cases was observed for almost all colon cancer sub-sites. The overall 5-year relative survival rate increased from 37.9% in 1998–2002 to 51.5% in 2008–2012. We showed an increase in survival rates for all stages and all sub-sites. In the most recent period, patients with a localized disease had a 5-year survival rate of 78.6%, while survival estimates for advanced cancer patients remained low at 6.6%. Conclusion: Although survival rates variated in colorectal cancer patients according to disease stages and sub-sites, we showed increased survival rates for all patients.


2021 ◽  
Author(s):  
Yingmei Li ◽  
Hongtao Wang ◽  
Zilong Lu ◽  
Jiandong Sun ◽  
Jiyu Zhang ◽  
...  

Abstract Background: Eye cancer is relatively rare. Current prevalence and disease burden of eye cancer are unlcear.The purpose of this study was to understand the epidemiology in the incidence and mortality of eye cancer in Shandong Province, and to provide reference for the prevention and control of eye cancer.Methods: Population-based cancer incidence and death data from cancer registries in 2013-2017 was collected by Shandong Center for Disease Control and Prevention (SDCDC). Extracted data were firstly assessed for data quality and then were aggregated by area (urban/rural), gender, and age group [0, 1-4, 5-9, 10-14, …, 85+]. Crude and age-adjusted incidence and mortality rates were calculated.Results: The reported numbers of eye cancer incident cases and deaths in Shandong cancer registry from 2013 to 2017 were 169 and 43, respectively. The crude incidence rate, age-standardized rate of incidence by Chinese population (ASRIC, 2000) and world population (ASRIW) were 11.12/107, 8.92/107 and 12.44/107, respectively. The crude mortality rate, age-standardized rate of mortality by Chinese population (ASRMC, 2000) and world population (ASRMW) were 2.83/107, 1.89/107 and 2.58/107, respectively. There were no marked differences in the incidence and mortality rates between male and female. The incidence rates were similar between rural and urban areas. The mortality rate in rural areas was higher than that in urban areas. The mortality-to-incidence (M/I) ratio in rural areas (0.30) was considerably higher than that in urban areas (0.18). The highest incidence was observed in children aged 0-4 years old, which was true for both urban and rural areas, and for both genders,Conclusion: Eye cancer is not a common malignant tumor in this population. Prevention and control measures should be tailored according to the epidemiological characteristics and risk factors of eye cancer.


2020 ◽  
Vol 38 (15_suppl) ◽  
pp. e16130-e16130
Author(s):  
Feng Gao ◽  
Peng Jing ◽  
Jian Liu ◽  
Wei Han ◽  
Xingyou Xu ◽  
...  

e16130 Background: To observe the effect of adjuvant on the clinical efficacy and survival period of patients with liver cancer treated by UMIPIC (Ultra-minimum Incision personalized intratumoral chemoimmunotherapy). Methods: 156 liver cancer patients who were treated with UMIPIC with hapten or without hapten from January 2011 to December 2015 were selected for the study objects, including 124 cases with hapten as studying group and 32 cases without hapten as comparing group. All patients signed the treatment consent, treated according to the treatment guidelines of UMIPIC, followed up for the efficacy and the survival period of all patients more than 3 months, and observed whether there was effect on the clinical efficacy, adverse reactions, survival period and survival rate of patients with liver cancer patients treated with UMIPIC. Results: The common side effects of hapten group were fever 45.16%, pain 27.42%, hemoglobin reduction 14.78%, leucopenia 11.97%, thrombocytopenia 10.26%, liver function damage 5.26%, nausea 4.03%, renal dysfunction 2.61%. No rash, neurotoxicity and hair loss were found; The common adverse reactions in the non hapten group were fever 40.63%, pain 25.00%, hemoglobin reduction 17.24%, leucopenia 13.79%, thrombocytopenia 10.34%, nausea 6.25%. No other adverse reactions were found; there was no difference between the two groups (P > 0.05). The benefit rate of hapten group was 89.06% lower than that of non hapten group (94.74%) (P > 0.05). According to the follow-up results, the mean and median survival time of hapten group was 26.421 and 9.930 months, significantly higher than that of non hapten (16.473 and 7.230 months) (P < 0.05).The 1-year, 2-year, 3-year and 5-year survival rates of adjuvant group respectively were 45.69%, 33.33%, 25.68% and 20.83%,The 1-year, 2-year, 3-year and 5-year survival rates in the adjuvant free group respectively were 27.50%, 20.59%, 14.81% and 14.29%, The 1-year survival rate of hapten group was significantly higher than that of non hapten group (P < 0.05). Conclusions: There is no significant difference in the adverse reactions and clinical efficacy of UMIPIC in the treatment of liver cancer patients with and without hapten. Adding hapten can significantly prolong the survival time and improve the survival rate of patients with liver cancer patients treated with UMIPIC.


2020 ◽  
Vol 10 (18) ◽  
pp. 6492
Author(s):  
Jeongbae Jeon ◽  
Solhee Kim ◽  
Gu Hyun Kang ◽  
Kyo Suh

Providing rapid access to emergency medical services (EMS) within the “golden time” for survival is important to improve the survival rate of emergency patients. This study analyzes the accessibility of EMS based on driving speed changes following real-time road traffic conditions by time to estimate vulnerable areas for EMS and survival rates of emergency patients. The key results of the network analysis based on real-time road speed and this evaluation of vulnerable areas by village level across South Korea reveal the different characteristics of urban and rural areas to access emergency medical facilities. In urban areas, road traffic congestion during rush hour delays the patients’ access time to EMS. In contrast, in rural areas, the long geographical distance to an emergency medical facility is a hurdle for receiving care from an EMS during the “golden time” because emergency medical facilities are mostly located in urban areas. The existing standard to assess vulnerable areas of EMS accessibility is based on the speed limit of roads, but the time may be underestimated because the speed limit alone does not reflect the real road conditions. The study results show that an effective way to increase the survival rate is receiving immediate first aid treatment, which means that the government should continuously train the public to perform cardiopulmonary resuscitation (CPR) as well as install automated external defibrillators (AEDs) in populated places, and train the public to use them. Reducing assess time to emergency medical centers in urban areas and providing additional manpower to help with first aid in rural areas are reasonable ways to improve the survival rate of emergency patients.


2021 ◽  
Vol 18 (1) ◽  
Author(s):  
Meng Wang ◽  
Ru-Ying Hu ◽  
Wei-Wei Gong ◽  
Jin Pan ◽  
Fang-Rong Fei ◽  
...  

Abstract Background Limited population-based studies have investigated the secular trend of prevalence of gestational diabetes mellitus (GDM) in mainland China. Therefore, this study aimed to estimate the prevalence of GDM and time trends in Chinese female population. Methods Based on Diabetes Surveillance System of Zhejiang Province, 97,063 diagnosed GDM cases aged 20–50 years were identified from January 1, 2016 to December 31, 2018. Annual prevalence, prevalence rate ratios (PRRs) and average annual percentage change with their 95% confidence intervals (CIs) were reported. Results The age-standardized overall prevalence of GDM was reported to be 7.30% (95% CI 7.27–7.33%); 9.13% (95% CI 9.07–9.19%) in urban areas and 6.24% (95% CI 6.21–6.27%) in rural areas. Compared with 20–24 years age group, women in advanced age groups (25–50 years) were at higher risk for GDM (PRRs ranged from 1.37 to 8.95 and the 95% CIs did not include the null). Compared with rural areas, the risk for GDM was higher in urban areas (PRR: 1.69, 95% CI 1.67–1.72). The standardized annual prevalence increased from 6.02% in 2016 to 7.94% in 2018, with an average annual increase of 5.48%, and grew more rapidly in rural than urban areas (11.28% vs. 0.00%). Conclusions This study suggested a significant increase in the prevalence of GDM among Chinese female population in Zhejiang province during 2016–2018, especially in women characterized by advanced age and rural areas.


2021 ◽  
Author(s):  
Silvia Marcela Ballesteros ◽  
José Moreno-Montoya ◽  
Wilhelmus Johannes Andreas Grooten ◽  
Pedro Barrera-López ◽  
José A. De la Hoz-Valle

Abstract BackgroundMultimorbidity prevalence in the elderly is increasing worldwide. Variations regarding the socioeconomic characteristics of the individuals and their context have been described, mostly in high-income scenarios. This study aims to assess the magnitude and the socioeconomic factors associated with variations on multimorbidity in Colombia.MethodsA cross-sectional multilevel study with a nationally representative sample of 23 694 Colombian adults aged 60 years and older was conducted. Individual socioeconomic, demographic, childhood and health related characteristics, as well as group level variables (multidimensional poverty index and infectious diseases mortality rate) were analyzed. A two-level stepwise structural equation model was used to simultaneously adjust the individual and contextual effects. ResultsMultimorbidity prevalence was 62.3% (95% CI 61.7–62.9). In the multilevel adjusted models, age, female sex, having functional limitations, non-white ethnicity, high body mass index, higher income, physical inactivity, poverty during childhood and living in urban areas were associated with multimorbidity. The mediation analysis showed that living in rural areas was significantly associated with infectious disease mortality rate and other individual associations with multimorbidity were mediated by the multidimensional poverty variable. ConclusionsThis paper demonstrates a strong association between multimorbidity and poverty in a low-middle income country. Differences in the factors involved in the etiology of multimorbidity are expected among wealthy and poor countries regarding availability and prioritization of health services.


2017 ◽  
Vol 3 (2_suppl) ◽  
pp. 10s-11s ◽  
Author(s):  
Alvaro Rivera-Andrade ◽  
Maria Fernanda Kroker-Lobos ◽  
Mariana Lazo ◽  
Neal Freedman ◽  
John Groopman ◽  
...  

Abstract 13 Background: The proportion of liver cancer (LC) that is linked to metabolic risk factors has been increasing in many countries. Guatemala has the highest reported incidence of LC in the Americas, 1 but the prevalence of metabolic risk factors is not clear. We undertook this work to examine the prevalence of metabolic risk factors for LC in Guatemala by sex and residence. Methods: We conducted a cross-sectional study of 461 adults older than 40 years who resided in rural and urban areas. Risk factors were defined by using physical exam and laboratory data, including anthropometry, blood pressure, fasting plasma glucose, serum liver enzymes, and lipids. Fatty liver disease (FLD) was defined as a fatty liver index score of > 60 and liver fibrosis (LF) as defined by a FIB-4 score of > 2.67. 2 , 3 Results: Among participants, 66% resided in rural areas and 57% were women. Mean ages of men and women were 58.0 ± 11.3 and 53.4 ± 9.8 years, respectively. Compared with men, women had higher prevalence of obesity (15% v 41%; P ≤ .001), metabolic syndrome (46% v 74%; P < .001), and FLD (67% v 52%; P < .001), but not LF (6% v 4%; P = .238). Compared with men and women from rural areas, those from urban areas had higher prevalence of diabetes (10% v 27%; P = .002; and 14% v 32%; P < .001) FLD (42% v 67%; P < .001; and 59% v 79%; P < .001), and metabolic syndrome (37% v 58%; P = .005; and 69% v 81%; P = .032), respectively. There was no difference in prevalence of LF by area among either men (6% v 6%; P = .86) or women (3% v 4%; P = .75). Conclusion: This study highlights a high prevalence of metabolic risk factors for LC in Guatemala, especially among women in urban areas. AUTHORS' DISCLOSURES OF POTENTIAL CONFLICTS OF INTEREST Alvaro Rivera-Andrade No relationship to disclose Maria Fernanda Kroker-Lobos No relationship to disclose Mariana Lazo No relationship to disclose Neal Freedman No relationship to disclose John Groopman No relationship to disclose Eliseo Guallar No relationship to disclose Carlos Mendoza-Montano No relationship to disclose Katherine McGlynn No relationship to disclose Josh Smith Research Funding: Abbott Nutrition Manuel Ramirez-Zea No relationship to disclose


2019 ◽  
Vol 47 (3) ◽  
pp. 1221-1231 ◽  
Author(s):  
Zhixiang Bian ◽  
Huiyi Gu ◽  
Peihua Chen ◽  
Shijian Zhu

Background The survival rate of patients undergoing hemodialysis and other renal replacement therapies has been extensively studied, but comparative studies of emergency and scheduled hemodialysis are limited. Methods This study included 312 patients who underwent emergency hemodialysis and 274 who received scheduled hemodialysis. We investigated the prognostic differences between these two groups of patients, including the short-term and long-term survival rates. Results The overall survival rate was significantly better among the patients in the scheduled hemodialysis group than emergency hemodialysis group. The mortality rate within 3 months of emergency hemodialysis was 4.8%, while that within 3 months of scheduled hemodialysis was 1.1%. Conclusions Significant differences were present between emergency and scheduled hemodialysis, especially the levels of serum creatinine and hemoglobin.


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