scholarly journals Evaluation of the Level of Salivary sHLA-G in Children Aged 3–5 Years with or without Dental Caries

2020 ◽  
Vol 2020 ◽  
pp. 1-6
Author(s):  
Mansoureh Bijani ◽  
Amrollah Mostafazadeh ◽  
Mina Motallebnejad ◽  
Ali Bijani ◽  
Roghiyeh Pourbagher ◽  
...  
Keyword(s):  
Dental Caries ◽  
Rank Correlation ◽  
Human Leukocyte ◽  
Cross Sectional Study ◽  
Host Immune System ◽  
Healthy Children ◽  
Cross Sectional ◽  
Spearman’S Rank Correlation ◽  
Significant Difference ◽  
The Mean

Aim and Background. Early childhood caries (ECC) is a common type of dental caries affecting children. As dental caries is a bacterial infectious disease, the host immune system parameters including soluble human leukocyte antigen-G (sHLA-G) are essential factors in estimating dental caries. The study aimed to investigate and compare the concentration of sHLA-G in the saliva of children with or without dental caries. Methods and Materials. This analytic cross-sectional study was carried out on 83 healthy children aged 3 to 5 years of both genders, who were divided into three groups based on decayed dental surfaces (ds): group 1, caries-free children (CF, n = 29); group 2, children with 1 ≤ ds ≤ 3, 1 ≤ ds ≤ 4, and 1 ≤ ds ≤ 5 for age 3, 4, and 5 years, respectively (ECC, n = 20); and group 3, children with ds ≥ 4, ds ≥ 5, and ds ≥ 6 for age 3, 4, and 5 years, respectively (S-ECC, n = 34). The unstimulated saliva samples were collected, and the salivary sHLA-G concentration was measured by the ELISA kit. The SPSS Statistics v17.0 software and Mann–Whitney, Kruskal–Wallis, chi-square, and Spearman’s rank correlation tests were used for statistical analysis. The level of significance was considered at p<0.05. Results. The mean concentrations of salivary sHLA-G in CF, ECC, and S-ECC groups were 3.18 ± 2.28, 5.64 ± 5.51, and 6.21 ± 6.03 ng/l, respectively (p=0.047), and the mean salivary sHLA-G level was comparatively higher in children with dental caries than that of the CF group (p=0.02), but there is no significant difference between ECC and S-ECC groups (p>0.05). Spearman’s rank correlation test showed a weak positive correlation (p=0.039, r = 0.22), between the level of salivary sHLA-G and dental caries. Conclusion. The present study provides some preliminary evidences on relationship between sHLA-G and dental caries in children.

scholarly journals THE IMPACT OF ASTHMAAND ITS MEDICATIONS ON DENTAL CARIES STATUS AND STREPTOCOCCUS MUTANS COUNT IN CHILDREN: A CROSS-SECTIONAL STUDY

2020 ◽  
pp. 20-23
Author(s):  
Sneha Upadhyay ◽  
Jyoti Bhavthankar ◽  
Mandakini Mandale ◽  
Nivedita Kaorey
Keyword(s):  
Dental Caries ◽  
Streptococcus Mutans ◽  
Cross Sectional Study ◽  
Control Group ◽  
Healthy Children ◽  
Sectional Study ◽  
Cross Sectional ◽  
Asthmatic Children ◽  
Significant Difference ◽  
The Impact

Background: Asthma and its medications have been linked to oral diseases in asthmatic children. Aim: Assessment of the dental caries status, salivary Streptococcus mutans count and S. mutans colony score in children receiving inhaled anti asthmatic medications and their comparison in healthy children Material and Method: A cross-sectional study was performed on 40 asthmatic children and 40 healthy children in the age group of 6-14 years. DMFT/deft indices were calculated and saliva samples were collected. Diluted saliva was inoculated on MSB agar plates. S. mutans count and colony score were analysed after 24-48 hours of inoculation. Results: Statistically significant difference was observed in the mean DMFT/deft index, salivary S. mutans load and S. mutans colony score in children of the asthmatic group and control group. Conclusion: Prevalence of dental caries and cariogenic bacteria is higher in asthmatic children.

scholarly journals Dental caries and the associated factors influencing it in tribal, suburban and urban school children of Tamil Nadu, India: a cross sectional study

2015 ◽  
Vol 4 (1) ◽  
Author(s):  
J. Baby John ◽  
Sharath Asokan ◽  
Aswanth KP ◽  
P.R. Geetha Priya ◽  
A.K. Shanmugaavel
Keyword(s):  
Dental Caries ◽  
School Children ◽  
Tamil Nadu ◽  
Urban School ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Hygiene Practices ◽  
Significant Difference ◽  
The Mean

<em>Background</em>. The study was planned to assess the prevalence of dental caries among tribal, suburban and urban children of Tiruchengode and Erode of Tamil Nadu state, India. The objective of the study was to assess the association of dental caries with family background, dental service availability, transportation and knowledge on preventive dental measures among these three groups.<br /> <em>Design and methods</em>. Cross-sectional study. A total of 1028 school children in the age range of 9-12 years from various government schools located in Palamalai and Kolli Hills (tribal), Tiruchengode (suburban) and Erode (urban), Tamil Nadu, were included in the study. Decayed, filled, and missing teeth (DMFT), decayed and filled teeth (dft) and Significant Caries Index were recorded. A specially prepared questionnaire was used to record all the data regarding oral hygiene practices, socioeconomic background, dental treatment availability, parent’s education level were used for the study. ANOVA t-test and post hoc test were used for comparing quantitative variables between the 3 subgroups. <br /><em>Results</em>. The tribal school children had 89.3% caries prevalence, where as it was 77% in suburban and 55% in urban school children. The mean DMFT score among tribal, suburban and urban school children were statistically significant different (P=0.001) between the three groups. There was a highly significant difference (P=0.001) in the mean DMFT score based on brushing frequency. There was a statistically significant difference (P=0.018) in the mean DMFT scores in the urban group based on the mothers education status. There were no statistically significant differences in the mean DMFT scores based on the presence or absence of television in their house and the parents’ income. <br /><em>Conclusions</em>. Oral hygiene practices, dietary habits and access to dental care services played an important role in prevalence of dental caries. It was observed that the socioeconomic status, parents’ educational status and mass media influenced the oral health of these children but without a significant contribution.

scholarly journals Cross-sectional study of effect of adiposity and hypertensive states on airway dynamics

2019 ◽  
Vol 7 (6) ◽  
pp. 2142
Author(s):  
Kunal Kishor Gautam ◽  
Deepak Saxena ◽  
Arvind Kanchan ◽  
Nisar Ahmad ◽  
Rahul Saini ◽  
...  
Keyword(s):  
Rank Correlation ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Group Iii ◽  
Pulmonary Functions ◽  
Spearman’S Rank Correlation ◽  
Group I ◽  
Significant Difference ◽  
Group Ii ◽  
Airway Dynamics

Background: Adiposity and hypertensive states are major burden for community. It causes many health-related issues, including problems related to respiratory system. It is proposed that pulmonary functions can be affected in obese hypertensive and obese normotensive adults compared to non-obese normotensive adults. The objective of the study was to find out the effect of adiposity and hypertensive states on the airway dynamics.Methods: About 30 male obese normotensives and 30 male obese hypertensive subjects were selected as study participants. 30 age-controlled non-obese, normotensive males were selected as controls. All participants were in the age group of 40 to 60 years. The pulmonary functions measured were FVC, FEV1, FEV1% and PEFR. All the participants performed 3 attempts of spirometry and maximum among the three recordings were used for analysis. ANOVA followed by Post hoc analysis to find out any significant differences between these groups. Spearman’s rank correlation was used.Results: There was a statistically significant differences in BMI between the group I and group II and III. There was a significant difference in SBP and DBP between obese normotensive (group II) and obese hypertensive (group III) subjects. There were significant decline in % predicted values of PFT parameters, on comparing obese normotensive and obese hypertensive when compared to non-obese normotensive participants. There were statistically significant negative correlations between age and FEV1 as well as BMI and PEFR.Conclusions: There was a significant decrease the pulmonary functions in obese normotensive and obese hypertensive adults in comparison to non-obese normotensive adults. It can be concluded that body weight and adiposity as well as high blood pressure creates deleterious effect on airway dynamics.

scholarly journals The Grammatical Abilities in a Speech Sample of Persian-speaking Children With Cochlear Implants

2020 ◽  
Vol 18 (4) ◽  
pp. 387-394
Author(s):  
Safieh Samiee ◽  
◽  
Nahid Jalilevand ◽  
Mohammad Kamali ◽  
Yahya Modarresi ◽  
...  
Keyword(s):  
Language Production ◽  
Study Groups ◽  
Cross Sectional Study ◽  
Healthy Children ◽  
Cross Sectional ◽  
Persian Language ◽  
Word Level ◽  
Significant Difference ◽  
The Mean ◽  
Hearing Children

Objectives: Studies reported that children with Cochlear Implant (Cl) presented difficulties in grammatical acquisition. The Persian language is inflectional. The present study aimed to compare word-level inflections in the language samples of CI recipients and healthy-hearing children. Methods: Thirty children were recruited in this descriptive-analytical cross-sectional study. The Language Sample Analysis (LSA) was used as a method of language production evaluation. Language samples were gathered using picture descriptions. A total of 3000 intelligible utterances were elicited and transcribed. An adaptation of the Language Assessment, Remediation, and Screening Procedure (LARSP) for Persian (P-LARSP), and the Mean Length of Utterance (MLU) techniques were used for the analyses of utterances. Results: The stages of language development of CI recipients were lower than those of the healthy children. The obtained results indicated a significant difference between children with CI and healthy-hearing children in MLU (P=0.0001). Moreover, we found a significant difference between the study groups in the mean frequency of word-level inflections (P=0.0001). Discussion: Children with CI use less word-level inflections, compared to their healthy-hearing counterparts.

scholarly journals Interleukin-37 as an anti-inflammatory cytokine: does its relation to disease activity suggest its potential role in rheumatoid arthritis therapy?

2021 ◽  
Vol 48 (1) ◽  
Author(s):  
Eman A. Baraka ◽  
Mona G. Balata ◽  
Shereen H. Ahmed ◽  
Afaf F. Khamis ◽  
Enas A. Elattar
Keyword(s):  
Rheumatoid Arthritis ◽  
Disease Activity ◽  
Cross Sectional Study ◽  
Healthy Controls ◽  
Tender Joint ◽  
Cross Sectional ◽  
Reactive Protein ◽  
Significant Difference ◽  
The Mean ◽  
Anti Inflammatory

Abstract Background This study aimed to measure the serum and synovial interleukin (IL)-37 levels in rheumatoid arthritis (RA) patients compared to patients with primary knee osteoarthritis (PKOA) and healthy controls and to detect its relation to RA disease activity. Results This cross-sectional study included 50 RA patients with a mean age of 40.24 ± 8.62 years, 50 patients with PKOA with a mean age of 56.69 ± 4.21, and 40 healthy controls with a mean age of 41.75 ± 7.38 years. The mean serum IL-37 level in the RA patients (382.6 ± 73.97 pg/ml) was statistically significantly (P < 0.001) the highest among the studied groups; however, it showed a non-significant difference between the PKOA patients (70.38 ± 27.49 pg/ml) and the healthy controls (69.97 ± 25.12 pg/ml) (P > 0.94). Both serum and synovial IL-37 levels were significantly positively correlated with disease activity scores (r = 0.92, P< 0.001 and r = 0.85, P < 0.001), tender joint counts (r = 0.83, P < 0.001 and r = 0.82, P < 0.001 ), swollen joint counts (r = 0.72, P < 0.001 and r = 0.60, P < 0.001), visual analog scale (r = 0.82, P < 0.001 and r = 0.82, P < 0.001), erythrocyte sedimentation rate (r = 0.75, P < 0.001 and r = 0.65, P < 0.001), and C-reactive protein (r = 0.93, P < 0.001 and r = 0.79, P < 0.001), respectively. Conclusion Serum and synovial IL-37 were significantly elevated in the RA patients, and they were closely correlated. Being less invasive, the serum IL-37 could be a marker of disease activity and could reflect the effective disease control by drugs. Having an anti-inflammatory effect could not suggest IL-37 as the key player to control inflammation alone, but its combination with other anti-proinflammatory cytokines could be investigated.

scholarly journals Differences in phosphatemia and frequency of consumption of dietary sources of phosphorus in hemodialysis patients in southern and northern Brazil

2019 ◽  
Vol 41 (1) ◽  
pp. 83-88 ◽  
Author(s):  
Fabiana Baggio Nerbass ◽  
Edcléia Regina Canzi ◽  
Renata dos Anjos Araujo ◽  
Dyane Corrêa ◽  
Rafaela Gonzaga dos Santos ◽  
...  
Keyword(s):  
Total Sample ◽  
Inorganic Phosphorus ◽  
Cross Sectional Study ◽  
The State ◽  
Cross Sectional ◽  
Significant Difference ◽  
Phosphorus Sources ◽  
Northern Brazil ◽  
The Mean ◽  
Pork Sausages

Abstract Introduction: Hyperphosphatemia is associated with unfavorable outcomes, and the percentage of patients presenting with this condition in hemodialysis (HD) in kidney foundation units in the state of Santa Catarina (SC) is historically higher than that of patients in the state of Tocantins (TO). Objective: To assess the frequency of consumption of the main dietary sources of phosphorus and to compare them between the two states. Methodology: A cross-sectional study was carried out involving 123 patients, 66 of SC and 57 of TO: 52% were men, average age was 46.9 ± 15.7 years, and mean HD time 48 (57-71) months. A food frequency questionnaire (FFQ) with 33 items that are dietary sources of phosphorus was applied. A consumption score was calculated for sources of organic, inorganic, and total phosphorus, and the six-month average of phosphatemia was obtained. Results: The mean phosphatemia of SC patients was higher (6.2 ± 1.5 vs 4.7 ± 1.3 mg/dL, p <0001) than TO patients, as well as the prevalence of hyperphosphatemia (62% vs 28%; p <10001). In the total sample, the foods most frequently consumed were milk and beans. Comparing the frequency of consumption between the two states, a significant difference was found in 17 items. In TO, beef and beans were the foods most frequently consumed, and in SC, fourteen other items of the FFQ (pork, sausages, dairy products, etc.) were the most frequently consumed. Phosphatemia correlated with the frequency of consumption of inorganic phosphorus sources. Conclusion: the frequency of consumption of several items was different between the states, and this explains the differences in phosphatemia between the two regions.

A Study on Bolton Anterior Tooth Size Discrepancies among Different Malocclusion Groups

2013 ◽  
Vol 1 (2) ◽  
pp. 1-4
Author(s):  
AW Ali ◽  
MZ Hossain
Keyword(s):  
Cross Sectional Study ◽  
Normal Group ◽  
Anterior Tooth ◽  
Tooth Size ◽  
Class Iii ◽  
Cross Sectional ◽  
Normal Occlusion ◽  
Significant Difference ◽  
The Mean ◽  
Bangladeshi Population

Aim: To investigate the correlation between anterior tooth size discrepancies among Angle's Class l, ll, lll malocclusions and corresponding normal occlusion, as well as their prevalence in Bangladeshi population. This study would act as a reference for diagnosis, treatment planning and assessment of prognosis in some orthodontic cases. Methods: This cross sectional study was conducted in the Department of Orthodontics & Dentofacial Orthopedics, Dhaka Dental College & Hospital. A total number of 200 subjects were selected in Angle's Class l, ll, lll and corresponding normal group. Each group had 50 subjects with males and females. A chi-square test was performed to statistically compare the prevalence of anterior tooth size discrepancies among Angle's Class l, ll, lll malocclusions and corresponding normal occlusion and two genders. Analysis of variance was used to compare the mean Bolton anterior tooth size ratios as a function of angle classification and gender. Statistical differences were determined at the 95% confidence level (p< 0.05). Results: No significant difference was observed in the mean Bolton anterior ratio between normal group and class-I malocclusion group (p = 0.343). Significant differences were observed between Class-II malocclusion and normal group (p=0.001), and also between Class-III malocclusion and normal group (p = 0.001). Individuals with Angle Class lll and Class ll malocclusions showed significantly greater prevalence of tooth size discrepancy than Class l malocclusion and corresponding normal group. Conclusion: The great diversity and ethnic mix of Bangladeshi population should alert our orthodontist to use Bolton analysis as an important diagnostic tool and become aware of the moderate variations that may be present and treated. It may somehow guide planning of this type of study in future. DOI: http://dx.doi.org/10.3329/bjodfo.v1i2.15982 Ban J Orthod & Dentofac Orthop, April 2011; Vol-1, No.2, 1-4

scholarly journals Usefulness of the Non-Contact Tonometry in Out-Patient Screening

2016 ◽  
Vol 15 (2) ◽  
Author(s):  
Satheesh Solomon T Selvin ◽  
Chris Elsa Samson Jacob ◽  
Thomas Kuriakose
Keyword(s):  
Central Corneal Thickness ◽  
Care Center ◽  
Corneal Thickness ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
Applanation Tonometry ◽  
Cross Sectional ◽  
Significant Difference ◽  
Iop Measurement ◽  
The Mean

Purpose: Goldmann applanation tonometry (GAT) is considered the gold standard for Intraocular Pressure (IOP) measurement. It has the disadvantages of being a contact device, need for a slit-lamp, non-portability and need of a skilled examiner. Many hospitals are using a Non Contact Tonometry (NCT) as a screening device to save clinician time, however the usefulness is not proved in terms of reliability. This study was aimed to determine the usefulness of the Air-puff tonometer (TONOREF NIDEK II, NIDEK CO., LTD., JAPAN) over a GAT in a tertiary care center. Design: Cross-sectional Study Methods: This was a cross-sectional, non interventional observational study conducted on 224 eyes (right eye) from 224 patients. All patients underwent the IOP measurement with both methods and a central corneal thickness (CCT) measured. The data was analyzed using SPSS 20.0 software. Results: The mean age of the patients was 40.3±11.29 years. There was a statistically significant difference (p<0.001) between the mean NCT and GAT readings which persisted even after correction for central corneal thickness. The correlation between NCT and GAT using Pearson’s correlation coefficient was strong irrespective of the corrections for their corneal thickness (r = 0.751 and 0.718 for uncorrected and corrected values respectively). The correlation of the individual clinicians for the readings varied from moderate to strong. The ROC curve showed the best sensitivity and specificity to occur at around 13 to 14 mmHg. Conclusion: NCT seems to overestimate the IOP at low ranges as compared to the GAT and underestimate at higher ranges. The crossover of the values is seen between 12 to 13 mmHg.  The clinician should do an individualized analysis of his/her GAT measurements to the readings of the NCT machine at the clinic to obtain clinician specific nomogram. 

scholarly journals The Oral Health Situation of 12-Year-Old School Children in the Rural Region of Ilembula in Southwestern Tanzania: A Cross-Sectional Study

2021 ◽  
Vol 18 (22) ◽  
pp. 12237
Author(s):  
Lisa Zumpe ◽  
Tobias Bensel ◽  
Andreas Wienke ◽  
Matilda Mtaya-Mlangwa ◽  
Jeremias Hey
Keyword(s):  
Dental Caries ◽  
Rural Areas ◽  
Primary Schools ◽  
Cross Sectional Study ◽  
Risk Indicators ◽  
Sectional Study ◽  
Cross Sectional ◽  
Factors Associated ◽  
Prophylactic Measures ◽  
The Mean

There has been no research on the prevalence of and factors associated with dental caries in rural southwestern Tanzania among schoolchildren. Determining the prevalence of and factors associated with dental caries will help to assess the need for dental intervention and prophylactic measures among children in the region. In February 2020, a cross-sectional study was conducted in the Wanging’ombe District of the Ilembula Ward. The data were collected through clinical examinations and personal interviews at two primary schools. Univariable and multivariable logistic regression analyses were performed to identify potential risk indicators for caries. The study included 319 students aged 11–12 years (average 11.92 ± 0.27 years). The mean Decayed, Missing and Filled Teeth index was 0.24 ± 0.68, and the mean Specific affected Caries Index was 1.66 ± 0.9. The greatest influences on the caries risk were poor oral hygiene (OR 8.05, 95% CI 0.49–133.23), low tooth brushing frequency (OR 3.03, 95% CI 1.26–7.26) and low level of education in parents (OR 2.63, 95% CI 0.99–6.98). Dental caries was low among students in rural areas in the Wanging’ombe District.

scholarly journals Factors influencing the dental caries in pregnant women: a cross-sectional study

2021 ◽  
Vol 10 (1) ◽  
pp. e32810111226
Author(s):  
Gabriela Bohrer Bolsson ◽  
Jessica Klöckner Knorst ◽  
Marília Cunha Maroneze ◽  
Maísa Casarin ◽  
Patrícia Pasquali Dotto ◽  
...  
Keyword(s):  
Dental Caries ◽  
Pregnant Women ◽  
Basic Research ◽  
Cross Sectional Study ◽  
Mean Value ◽  
Sectional Study ◽  
Cross Sectional ◽  
The Mean ◽  
The City ◽  
Santa Maria

Objective: To assess factors associated with the average number of dental caries in pregnant women. Method: Basic research design: This cross-sectional study was performed between January 2017 and December 2018 in Santa Maria, Brazil. Clinical setting and participants: Multistage random sampling resulted in the recruitment of 256 pregnant women from public health centers across the city. Clinical exams and semi-structured questionnaires including demographic, socioeconomic and behavioral questions were performed by trained interviewers. Main outcome measure: The experience of dental caries was evaluated through the mean value of the Decay, Missing, and Filled Surface Index (DMFS) by 4 trained and calibrated examiners. Multilevel Poisson regression models were used to evaluate the influence of different variables on the average number of dental caries. Rate ratio (RR) and respective 95% confidence intervals were calculated (CI 95%). Results: The prevalence of untreated dental caries was 62.7% in the sample, while the mean DMFS index was 10.27 (± 10.92). Women who smoked during pregnancy had a higher mean DMFS (RR 1.41; 95% CI 1.25-1.57). Furthermore, pregnant women who had poor self-ratings of oral health had a higher average DMFS (RR 1.21; 95% CI 1.10-1.32). Conclusions: The results showed that older age, ethnicity, fewer years in education and the presence of dental plaque resulted in higher means of DMFS.

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