Abstract P074: Heterogeneity In Proportional Mortality Due To Atherosclerosis By Age Amongst Asian Americans

Circulation ◽  
2021 ◽  
Vol 143 (Suppl_1) ◽  
Author(s):  
Abhyuday Chauhan ◽  
Deepak R Nair ◽  
Dhananjay Vaidya
Keyword(s):  
Asian American ◽  
Asian Indians ◽  
Linear Models ◽  
Age Groups ◽  
The Elderly ◽  
Older Age ◽  
Mortality Data ◽  
Age Difference ◽  
Mortality Burden ◽  
Proportional Mortality

Background: Asian American subgroups (AAS) differ amongst one another in terms of proportion of mortality (PM) due to atherosclerosis disease (ASD). However, differences in PM based on early onset (35-64 years) and older age (≥65 years) ASD deaths within each subgroup have not been well studied. Methods: US resident death records were examined from 2017 mortality data (National Center for Health Statistics). Race/ethnicity and underlying ASD cause (ICD-10 code of ischemic heart disease I20-I25, ischemic stroke I69, atherosclerosis I70, respectively) were tabulated for Asian-American subgroups and major US race/ethnicities (listed in Table). Age and sex standardized PM percentage was calculated overall for each ethnicity and separately for early and older age deaths within each ethnic group. The age by ethnicity interaction was tested using general linear models. Results: Over all ages, Filipinos and Asian Indians had the highest ASD PM while Vietnamese and Japanese had the lowest ASD PM, with other groups being intermediate. Compared with NHW, ASD PM was high in both age groups for Asian Indians and Filipino, while age difference PM in these ethnic groups was no different when compared to NHW – suggesting early and persistently high ASD. In contrast, Amerindians, Hispanics, Koreans and Chinese when compared to NHW had a low early age ASD PM, increasing significantly at older ages, suggesting the mortality burden is mostly at older ages. Conclusion: AAS are heterogeneous in terms of the overall burden of percent ASD mortality and the age at which it predominates. Asian Indians and Filipinos had the highest PM burden due to ASD over all ages, premature and older. On the other hand, premature ASD mortality burden was lowest in Koreans and Chinese amongst the AAS with a disproportionate increase in death in the elderly population. AAS subgroups need different strategies for prevention, with Asian Indians and Filipinos being targeted earlier in their life course.

scholarly journals Mortality due to respiratory diseases in the elderly after influenza vaccination campaigns in the Federal District, Brazil, 1996-2009

2013 ◽  
Vol 39 (2) ◽  
pp. 198-204 ◽  
Author(s):  
Francisca Magalhães Scoralick ◽  
Luciana Paganini Piazzolla ◽  
Liana Laura Pires ◽  
Cleudsom Neri ◽  
Wladimir Kummer de Paula
Keyword(s):  
Mortality Rate ◽  
Influenza Vaccination ◽  
Respiratory Diseases ◽  
Positive Impact ◽  
Vaccination Campaign ◽  
Age Groups ◽  
Federal District ◽  
The Elderly ◽  
Analysis Data ◽  
Proportional Mortality

OBJECTIVE: To compare mortality rates due to respiratory diseases among elderly individuals residing in the Federal District of Brasília, Brazil, prior to and after the implementation of a national influenza vaccination campaign. METHODS: This was an ecological time series analysis. Data regarding the population of individuals who were over 60 years of age between 1996 and 2009 were obtained from official databases. The variables of interest were the crude mortality rate (CMR), the mortality rate due to the respiratory disease (MRRD), and the proportional mortality ratio (PMR) for respiratory diseases. We performed a qualitative analysis of the data for the period prior to and after the implementation of the vaccination campaign (1996-1999 and 2000-2009, respectively). RESULTS: The CMR increased with advancing age. Over the course of the study period, we observed reductions in the CMR in all of the age brackets studied, particularly among those aged 80 years or older. Reductions in the MRRD were also found in all of the age groups, especially in those aged 80 years or older. In addition, there was a decrease in the PMR for respiratory diseases in all age groups throughout the study period. The most pronounced decrease in the PMR for respiratory diseases in the ≥ 70 year age bracket occurred in 2000 (immediately following the implementation of the national vaccination campaign); in 2001, that rate increased in all age groups, despite the greater adherence to the vaccination campaign in comparison with that recorded for 2000. CONCLUSIONS: Influenza vaccination appears to have a positive impact on the prevention of mortality due to respiratory diseases, particularly in the population aged 70 or over.

scholarly journals Pulmonary tuberculosis among men over forty

1959 ◽  
Vol 57 (4) ◽  
pp. 367-385 ◽  
Author(s):  
Cecily M. Tinker
Keyword(s):  
Royal College ◽  
Age Groups ◽  
The Elderly ◽  
Older Age ◽  
Personal Hygiene ◽  
Tuberculous Infection ◽  
Elderly Men ◽  
Female Population ◽  
Heavy Smoking ◽  
Increased Risk

1. A review of the few studies so far made on the high mortality from tuberculosis among elderly men, and a consideration of the available statistics, indicate that urbanization is one of the principal factors responsible.2. In the present inquiry, which was confined to London, 445 newly diagnosed cases of tuberculosis in men over 40, together with the same number of paired controls, were studied by means of a questionnaire and of personal interview.3. It was found that the tuberculous patients differed significantly from the controls in the following characteristics; Scots, Irish, Welsh, or foreign nationality; single, widower or divorced; resident in common lodging houses or hostels; inadequate or special diet; history of gastrectomy; a winter cough; shortness of breath; insufficient sleep; and heavy drinking and smoking. On the other hand, overtime or night work, diabetes, rheumatoid arthritis, asthma, and mental illness were distributed fairly evenly in the two groups.4. Unfortunately no group of elderly women exists in this country living under the same sort of conditions as the elderly men studied here, so that it was impossible to determine how far the various factors considered were responsible for the high rate of late adult male tuberculosis. A study, however, of a population of established civil servants living under ordinary conditions revealed little difference between the observed rates of tuberculosis and those expected on the basis of national notification figures for men and women in the older age groups.5. It appears that a low standard of personal hygiene, associated especially with heavy smoking and drinking and residence in loading houses, predispose to the development of tuberculosis in the elderly male. Part of the evil effect of living in common lodging houses in particular may be due to the increased risk of exposure to tuberculous infection that it entails.6. It is tentatively concluded that the casual workers of an urbanized community are one of the principal reservoirs of tuberculous infection in large towns, and since there is no numerically comparable female population, this group, and its immediate male contacts, account in large measure for the difference between the male and female tuberculosis rates in the older age groups.This work was initiated during the tenure of a Prophit Scholarship of the Royal College of Physicians, and completed with the aid of a grant from the Medical Research Council.I am indebted to members of the Prophit Committee of the Royal College of Physicians for their support and encouragement, and most particularly to Dr G. S. Wilson, Director of the Public Health Laboratory Service, under whose guidance the work was carried out. Figures relating to the incidence of tuberculosis in the Civil Service are published by kind permission of Dr W. E. Chiesman, Treasury Medical Adviser, and Dr M. C. W. Long, Dr J. W. Parks, and Dr H. Stannus Stannus, whose departmental records were used to compute the figures.I am greatly indebted to the consultants and staff of the seventeen chest clinics who co-operated in the investigation, for their interest and help in tracing patients, and to the medical superintendents of numerous sanatoria and chest hospitals, and to the surgeons who permitted me to interview patients under their care as controls.I should like also to acknowledge the assistance received from the medical officers of health of the metropolitan boroughs who kept me informed of notifications from lodging houses in their areas, and supplied information about the accommodation.

scholarly journals Deprescribing Antihypertensive Drugs in Patients of Older Age Groups

2020 ◽  
Vol 16 (1) ◽  
pp. 82-93
Author(s):  
O. D. Ostroumova ◽  
M. S. Cherniaeva ◽  
D. A. Sychev
Keyword(s):  
Elderly Patients ◽  
Dose Reduction ◽  
Randomized Clinical Trials ◽  
Drug Withdrawal ◽  
Antihypertensive Drugs ◽  
Age Groups ◽  
Economic Cost ◽  
The Elderly ◽  
Older Age ◽  
Additional Tool

Arterial hypertension (AH) is one of the most common diseases in the elderly. It has been proven that lowering blood pressure (BP) is effective in preventing stroke and cardiovascular complications in patients even at the age of ≥80 years. On the other hand, there is evidence that a significant decrease in BP can be harmful to older people and may lead to a higher risk of overall mortality. Therefore, existing guidelines for the treatment of AH determine specific approaches for managing patients of older age groups, where the target BP levels are determined not only by age and concomitant diseases, but also by the presence of frailty. Moreover, there is a need to monitor the dynamics of frailty indicators (social, functional, cognitive and mental status of the patient), since their deterioration may require changes in the tactics of antihypertensive therapy (dose reduction, drug withdrawal or replacement) and changes in target BP levels. In this regard, in recent years, the possibility/necessity of a planned and controlled process of dose reduction, drug withdrawal or replacement, if this drug can be harmful and/or does not bring benefits (deprescribing), has attracted attention. This article is a review of current literature, which presents the design and main characteristics of randomized clinical trials (RCTs) and systematic reviews on the deprescribing of antihypertensive drugs in elderly patients with AH and frailty. An analysis of these studies showed the benefits of deprescribing of antihypertensive drugs for elderly patients with frailty, which avoids potential harm to their health, improves the quality of life and reduces the economic cost of treatment. Therefore, deprescribing of antihypertensive drugs can be used as an additional tool to achieve the necessary target BP values in patients of an older age group. However, for the development of deprescribing of antihypertensive drugs schemes and its introduction into clinical practice, the results of large specially planned RCTs are needed to study this issue.

scholarly journals Temporal Lobe Epilepsy in the Elderly

2012 ◽  
Vol 2012 ◽  
pp. 1-5 ◽  
Author(s):  
L. E. Morillo
Keyword(s):  
Life Expectancy ◽  
Temporal Lobe Epilepsy ◽  
Temporal Lobe ◽  
Age Groups ◽  
The Elderly ◽  
Bimodal Distribution ◽  
Older Age ◽  
World Population ◽  
Epilepsy In The Elderly ◽  
The World

The incidence of epilepsy has bimodal distribution peaking at the extremes of life. Incidence is greater in younger and older age groups (Hauser et al., 1993, Sidenvall et al., 1993, Forsgren et al., 1996, and Olafsson et al., 2005). As the world population ages more elders with epilepsy will be identified. In the high-income countries with longer life expectancy, the number of elders with epilepsy will be even higher. CPSs account for 40% of all seizure types in the elderly (Hauser et al., 1992); however, the proportion with temporal lobe epilepsy (TLE) is uncertain.

scholarly journals The Influence of Covid-19 Vaccine on Daily Cases, Hospitalization, and Death Rate in Tennessee: A Case Study in the United States

2021 ◽  
Author(s):  
Ali Roghani
Keyword(s):  
Death Rate ◽  
Age Groups ◽  
Vaccination Strategy ◽  
The Elderly ◽  
The United States ◽  
Hospitalization Rate ◽  
Older Age ◽  
Study Cohort ◽  
Lower Death Rate

The COVID-19 outbreak highlights the vulnerability to novel infections, and vaccination remains a foreseeable method to return to normal life. However, infrastructure is inadequate for the whole population to be vaccinated immediately. Therefore, policies have adopted a strategy to vaccinate the elderly and vulnerable population while delaying others. This study uses the Tennessee official statistic from the onset of COVID vaccination (17th of December 2021) to understand how age-specific vaccination strategies reduce daily cases, hospitalization, and death rate. The result shows that vaccination strategy can significantly influence the numbers of patients with COVID-19 in all age groups and lower hospitalization and death rates just in older age groups. The Elderly had a 95% lower death rate from December to March; however, and no change in the death rate in other age groups. The Hospitalization rate was reduced by 80% in this study cohort for people aged 80 or older, while people who were between 50 to 70 had almost the same hospitalization rate. The study indicates that vaccination targeting older age groups is the optimal way to avoid higher transmissions and reduce hospitalization and death rate for older groups.

AGE-RELATED AND POST-EXTRACTION ATROPHY OF THE JAWS AND MODERN POSSIBILITIES FOR RESTORING THE MASTICATORY APPARATUS IN THE ELDERLY PEOPLE

2021 ◽  
pp. 134-143
Author(s):  
М.И. Музыкин ◽  
Е.В. Коковихина ◽  
Е.А. Герасимова ◽  
В.Ф. Мищук ◽  
А.К. Иорданишвили ◽  
...  
Keyword(s):  
Age Groups ◽  
Clinical Manifestations ◽  
The Elderly ◽  
Older Age ◽  
Leningrad Region ◽  
Stage Of Development ◽  
Age Related ◽  
Number Of Patients ◽  
Dental Rehabilitation ◽  
Masticatory Apparatus

Представлены данные клинического обследования 3 329 человек (1 760 мужчин и 1 569 женщин), проживающих в различных регионах РФ (Санкт-Петербург и Ленинградская обл., Москва и Московская обл., Краснодарский край). Цель работы заключалась в изучении частоты утраты зубов и клинических проявлений атрофии альвеолярных отростков (частей) челюстей у пациентов старших возрастных групп для оценки возможности стоматологической реабилитации с использованием ортопедических конструкций на дентальных имплантатах. Изучение распространенности и степени атрофии показало, что в старшей возрастной группе у пациентов в большей мере преобладала 4-я и 5-я степень атрофии, частота встречаемости составила около 20-30 %. Встречаемость 6-й степени атрофии также была выше, чем в других возрастных группах, - она была обнаружена у 17,22 % мужчин и 17,81 % женщин на верхней челюсти и у 22,18 и 15,79 % - на нижней челюсти соответственно. Несмотря на то, что количество пожилых пациентов с полной или частичной утратой зубов не имеет тенденции к снижению, на современном этапе развития стоматологии и дентальной имплантологии восстановление целостности жевательного аппарата с применением искусственных опор возможно фактически во всех клинических случаях. Наличие коморбидной или мультиморбидной патологии не является абсолютным противопоказанием, а является лишь временны΄м фактором, откладывающим стоматологическую реабилитацию до стабилизации общесоматического статуса пациента. The data of clinical examination of 3 329 people (1 760 men and 1 569 women) living in various regions of the Russian Federation (St. Petersburg and Leningrad region, Moscow and Moscow region, Krasnodar Territory) are presented. The aim of the investigation was to study the frequency of tooth loss and clinical manifestations of atrophy of the alveolar processes (parts) of the jaws in patients of older age groups to assess the possibility of dental rehabilitation using orthopedic structures on dental implants. The study of the prevalence and degree of atrophy showed that in the older age group, patients of senile age were more dominated by 4 and 5 degrees of atrophy, the frequency of their occurrence was about 20-30 %. The incidence of grade 6 atrophy was also higher than in other age groups, it was found in 17,22 % of men and 17,81 % of women in the upper jaw and 22,18 % and 15,79 % in the lower jaw, respectively. Despite the fact that the number of patients in older age groups with complete or partial loss of teeth does not tend to decrease, at the present stage of development of dentistry and dental implantology, the possibility of restoring the integrity of the masticatory apparatus with the use of artificial supports is possible in virtually all clinical cases. The presence of comorbid or multimorbid pathology is not an absolute contraindication, but is only a temporary factor that postpones dental rehabilitation until the general somatic status of the patient is stabilized.

ASSOCIATION BETWEEN PERCEIVED ETHNIC DISCRIMINATION AND HEALTH: EVIDENCE FROM THE NATIONAL LATINO & ASIAN AMERICAN STUDY (NLAAS)

2016 ◽  
pp. 1-7
Author(s):  
C. SIORDIA ◽  
Y.D. COVINGTON-WARD
Keyword(s):  
Asian American ◽  
Social Stress ◽  
Linear Models ◽  
Age Groups ◽  
Quantitative Relationship ◽  
Ethnic Discrimination ◽  
American Study ◽  
Cross Sectional ◽  
Neighborhood Perception ◽  
Perceived Ethnic Discrimination

Background: The field of aging studies continues to better understand between-racial-group health disparities. Previous work provides empirical evidence for a statistical relationship between perceived discrimination and adverse health across all age groups. Specific Aim: We contribute to the literature by investigating the quantitative relationship between Perceived Ethnic Discrimination (PED), Self-Rated Physical Health (SR-PH), Self-Rated Mental Health (SR-MH), and their combined score (SR-PH-MH). Setting & Design:The cross-sectional observational study used data collected between 2002 and 2004 from the National Latino and Asian American Study (n=4,559; average age=41; 54% female; 18% Mexican; 36% Non-Mexican Latinos; 12% Chinese; 31% Non-Chinese Asians). We provide descriptive statistics for those below and at or above age 65. Results: Multivariable linear models adjusting for age, sex, ethnicity, education, body mass index, and neighborhood perception provide evidence that although a small effect, PED explains between-people variance in SR-PH (β=-0.01; α=0.001), SR-MH (β=-0.03; α=0.001), and SR-PH-MH (β=-0.04; α=0.001). Conclusions: The analysis supports arguments that PED has a non-random association with health. As we continue to explore novel measures of frailty, markers of social stress should be considered.

Attitudes toward Aging in a Southwestern Sample: Effects of Ethnicity, Age, and Sex

1988 ◽  
Vol 62 (3) ◽  
pp. 735-746 ◽  
Author(s):  
Mary B. Harris ◽  
Polly Page ◽  
Cynthia Begay
Keyword(s):  
American Indians ◽  
Age Groups ◽  
The Elderly ◽  
Older Age ◽  
Old People ◽  
Attitudes Toward Aging ◽  
Old Men ◽  
Age And Sex

The present study, conducted in a Southwestern community, surveyed 257 adults varying in ethnicity, age, and sex on several measures of attitudes toward aging. Contrary to most previous research, the attitudes were positive in all groups, with persons aged sixty years or older giving the most positive responses on a number of items. American Indians and Hispanics were more likely to enjoy spending time with old people than Anglo-Americans, who, in turn, were more likely to disagree that people do not do much when they are old. Men were more likely to look forward to growing old than women and wished to reach an older age. In general, subjects from all ethnic, sex, and age groups reported being satisfied with their lives. The results suggest that the stereotypes of the elderly today are no longer primarily negative.

scholarly journals HEALTH PROMOTION IN OLDER AGE GROUPS AS AN OBJECTIVE OF THE SENIOR POLICY: EUROPEAN CHALLENGES

2017 ◽  
Vol 3 ◽  
pp. 377
Author(s):  
Arkadiusz Marzec
Keyword(s):  
Physical Activity ◽  
Health Promotion ◽  
Motor Coordination ◽  
Age Groups ◽  
The Elderly ◽  
Older Age ◽  
Physical Endurance ◽  
Local Environments ◽  
Oriented Activity ◽  
High Level

Successful ageing is understood to mean a satisfactory health status, high level of financial independence, firm family and social ties and opportunities for self-realization. The best form of health promotion among the elderly is to promote physical activity. Physical and recreational health-oriented activity and prevention of diseases helps improve physical endurance and strength, and increase muscle mass, flexibility and overall motor coordination. Adequate level of physical exercise at older age effectively prevents ageing processes and ensures maintaining good psychophysical fitness, thus stimulating social integration. The study presents selected forms of recreational forms of physical activity of older adults in local environments resulting from the needs of this group of people and initiatives of local self-governments to promote health.

scholarly journals Optimal strategies for quarantine stopping in France – General expected patterns of strategies focusing on contact between age groups

2020 ◽  
Author(s):  
Benjamin Roche ◽  
Andres Garchitorena ◽  
David Roiz
Keyword(s):  
High Efficiency ◽  
Age Groups ◽  
Optimal Strategies ◽  
The Elderly ◽  
Age Classes ◽  
Epidemic Curve ◽  
Mobility Data ◽  
Mortality Burden ◽  
Expected Mortality

AbstractDue to the COVID-19 pandemic, many countries have implemented a complete lockdown of their population that may not be sustainable for long. To identify the best strategy to replace this full lockdown, sophisticated models that rely on mobility data have been developed. In this study, using the example of France as a case-study, we develop a simple model considering contacts between age classes to derive the general impact of partial lockdown strategies targeted at specific age groups. We found that epidemic suppression can only be achieved by targeting isolation of young and middle age groups with high efficiency. All other strategies tested result in a flatter epidemic curve, with outcomes in (e.g. mortality and health system over-capacity) dependent of the age groups targeted and the isolation efficiency. Targeting only the elderly can decrease the expected mortality burden, but in proportions lower than more integrative strategies involving several age groups. While not aiming to provide quantitative forecasts, our study shows the benefits and constraints of different partial lockdown strategies, which could help guide decision-making.

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