scholarly journals Practical aspects of milk collection in the rat

1995 ◽  
Vol 29 (4) ◽  
pp. 450-455 ◽  
Author(s):  
C. T. Rodgers
Keyword(s):  
Young Children ◽  
Pregnant Women ◽  
Study Design ◽  
Safety Evaluation ◽  
Basic Study ◽  
Milk Samples

It is a requirement as part of the safety evaluation of novel compounds, which are intended to be administered to pregnant women or women with young children, that the potential for the compound or its metabolites to be transferred from a dam to its litter during lactation is measured. The data obtained from the rat milking studies are also used to support the rat peri- and post-natal studies. Therefore it is necessary to collect multiple milk samples from lactating rats. In this paper it was decided to concentrate on three areas: 1. The factors which had to be considered during the development of the rat milking technique; 2. The outline of the basic study design for a rat milking study; 3. The technique for milking rats.

scholarly journals Exploring maternal nutrition counseling provided by health professionals during antenatal care follow-up: a qualitative study in Addis Ababa, Ethiopia-2019

BMC Nutrition ◽  
2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Matyas Atnafu Alehegn ◽  
Tsegaye Kebede Fanta ◽  
Agumas Fentahun Ayalew
Keyword(s):  
Pregnant Women ◽  
Study Design ◽  
Health Professionals ◽  
Maternal Nutrition ◽  
Addis Ababa ◽  
Nutrition Counseling ◽  
Institutional Barriers ◽  
Size Adjustment ◽  
Sample Size Adjustment ◽  
Pregnant Mothers

Abstract Background Nutritional awareness and practice of women during pregnancy could be determining their nutritional status, which significantly affects the outcome of pregnancy. Therefore this study aims to explore the maternal nutrition counseling provided by health professionals for pregnant women, Barriers to maternal nutrition, and major interventions. Methods A descriptive study design with a qualitative method by using ground theory tradition, based on constructivist research approach and Charmaz’s (2000) study design has been conducted from September-01/2019 _November-16/2019 among pregnant women who got ANC service in Addis Ababa, Ethiopia. A purposive sampling technique was used. Practical observations and in-depth interviews were conducted. The sample size adjustment has been carried out according to the information saturation obtained, and finally, 81 practical observations, In-depth interview with two center managers, nine health professionals and eleven term pregnant women has been conducted. An observational checklist and Semi-structured, open-ended questionnaires were used. Data, the environment, and methodological triangulation were carried out. A conceptual framework has been established based on the data collected about the whole process of maternal nutrition counseling during pregnancy. ATLAS TI software was utilized for information analysis. The results Most participants responded that maternal nutrition counseling provided to pregnant mothers is not adequate and neglected by most stakeholders. From 81 practical observations, health professionals counseled to mothers were 10 what to feed, 4 what to limit to consume, and 5 were counseled about what to eat during pregnancy. Close to all the respondents agreed on the importance of providing nutrition counseled by the nutritionists. Most of the study participants emphasized a shortage of time as primary barriers. Institutional Barriers, Professional Barriers, Maternal Barriers, and Community Barriers were major barriers to nutrition counseling. Conclusions Generally, maternal nutrition counseling provided to pregnant mothers was not adequate and neglected by most stakeholders. Shortage of time due to client flow, Institutional Barriers, Professional Barriers, Maternal Barriers, and Community Barriers were major categories of maternal nutritional counseling barriers. Information update and timely preparation were recommended to health professionals.

scholarly journals Design of a prospective follow-up study on early parenthood and smoking behaviour during pregnancy in Finnish primary healthcare

2021 ◽  
pp. 140349482110224
Author(s):  
Mikael O. Ekblad ◽  
Hanna P. Wallin ◽  
Marjukka Pajulo ◽  
Päivi E. Korhonen
Keyword(s):  
Pregnant Women ◽  
Study Design ◽  
Primary Healthcare ◽  
Routine Data ◽  
Smoking Behaviour ◽  
Self Report ◽  
Health Clinic ◽  
Follow Up Study ◽  
Study Population

Aims: The primary aim of the study is to explore different factors affecting parents’ smoking behaviour, and especially how smoking may be connected with individual differences in the psychological process of becoming a parent. In the current paper, we present the study design together with basic information on the study population. Methods: The Central Satakunta Maternity and Child Health Clinic (KESALATU) Study is an ongoing prospective follow-up study in primary healthcare of the Satakunta region of southwest Finland. Families were recruited during their first maternity clinic visit between 1 September 2016 and 31 December 2019, and participation will continue until the child is 1.5 years of age. The study combines different sources and types of data: e.g. routine data obtained from primary healthcare clinic records, specific parental self-report data and data from a new exhaled carbon monoxide meter indicating maternal smoking. The data are collected using frequently repeated assessments both during pregnancy and postnatally. The methods cover the following areas of interest: family background factors (including smoking and alcohol use), self-reported parental–foetal/infant attachment and mentalization, self-reported stress, depression and quality of life. Results: 589 pregnant women and their partners were asked to participate in the study during the collection time period. The final study population consisted of 248 (42.1%) pregnant women and 160 (27.1%) partners. Conclusions: The new methods and study design have the potential to increase our understanding about the link between early parenting psychology, prenatal psychosocial risk factors and parental health behaviour.

Vitamins for the First 1000 Days: Preparing for Life

2012 ◽  
Vol 82 (5) ◽  
pp. 342-347 ◽  
Author(s):  
Ibrahim Elmadfa ◽  
Alexa L. Meyer
Keyword(s):  
Vitamin D ◽  
Folic Acid ◽  
Young Children ◽  
Pregnant Women ◽  
Bone Mineralization ◽  
Type I ◽  
Lactation Performance ◽  
Balanced Diet ◽  
Diabetes Mellitus Type I ◽  
In Pregnancy

Vitamins are essential nutrients for many body functions and particularly important during growth. Adequate supply in pregnancy and in early infancy is therefore crucial, but there is still a lack of knowledge about the needed amounts of vitamins of children older than six months and also during pregnancy. Recommendations for intake levels are generally derived by extrapolation from data for infants based in turn on the contents in breast milk and those for adults. A vitamin of particular importance in pregnancy is folic acid due to its role in the development of the brain and nerve system and the prevention of fetal neural tube defects (NTD). Mandatory fortification of flour and certain other grain products in many countries has been associated with a reduction in NTD incidence. However, other deficiencies or suboptimal status of B vitamins, especially B6 and B12 have been repeatedly reported in pregnant women also in high-income countries. Vitamin A is one of the three most critical micronutrients globally and pregnant women and young children are especially vulnerable to deficiencies. Night blindness, anemia, and immunodeficiency are major consequences of inadequate supply in these populations. Much attention has recently been accorded vitamin D that is also critical in pregnant women and young children for instance because of its involvement in bone mineralization but also its more recently discovered immune-modulating function that is thought to prevent development of autoimmune diseases like diabetes mellitus type I. A healthy balanced diet provides the best basis for optimal pregnancy outcome, lactation performance, and complementary feeding. However, supplements or fortified foods may be needed to cover the high requirements especially of critical vitamins such as vitamin D and folic acid and to correct unfavorable dietary patterns in women or to adapt foods to the needs of young children.

scholarly journals Pregnancy and Breastfeeding During COVID-19 Pandemic: A Systematic Review of Published Pregnancy Cases

2020 ◽  
Vol 8 ◽  
Author(s):  
Carina Rodrigues ◽  
Inês Baía ◽  
Rosa Domingues ◽  
Henrique Barros
Keyword(s):  
Systematic Review ◽  
Adverse Effects ◽  
Pregnant Women ◽  
Pregnancy Outcomes ◽  
Web Of Science ◽  
Study Quality ◽  
Neonatal Deaths ◽  
Live Births ◽  
Milk Samples ◽  
The Impact

Background: The COVID-19 pandemic is an emerging concern regarding the potential adverse effects during pregnancy. This study reviews knowledge on the impact of COVID-19 on pregnancy and describes the outcome of published cases of pregnant women diagnosed with COVID-19.Methods: Searches were conducted in PubMed®, Scopus®, Web of Science®, and MedRxiv® up to 26th June 2020, using PRISMA standards, to identify original published studies describing pregnant women at any gestational age diagnosed COVID-19. There were no date or language restrictions on the search. All identified studies were included irrespective of assumptions on study quality.Results: We identified 161 original studies reporting 3,985 cases of pregnant women with COVID-19 (1,007 discharged while pregnant). The 2,059 published cases with pregnancy outcomes resulted in 42 abortions, 21 stillbirths, and 2,015 live births. Preterm birth occurred in 23% of cases. Around 6% of pregnant women required admission to an intensive care unit and 28 died. There were 10 neonatal deaths. From the 163 cases with amniotic fluid, placenta, and/or cord blood analyzed for the SARS-CoV-2 virus, 10 were positive. Sixty-one newborns were positive for SARS-CoV-2. Four breast milk samples from 92 cases showed evidence of SARS-CoV-2.Conclusion: Emerging evidence suggests that vertical transmission is possible, however, there is still a limited number of reported cases with intrapartum samples. Information, counseling and adequate monitoring are essential to prevent and manage adverse effects of SARS-CoV-2 infection during pregnancy.

scholarly journals Pertussis in a child of the first month of life from family contact

2021 ◽  
Vol 13 (2) ◽  
pp. 149-153
Author(s):  
O. V. Iozefovich ◽  
S. M. Kharit ◽  
E. I. Bobova ◽  
E. A. Budnikova
Keyword(s):  
Young Children ◽  
Pregnant Women ◽  
Clinical Observation ◽  
Whooping Cough ◽  
Pertussis Infection ◽  
Early Stages ◽  
Parents And Children ◽  
The Family ◽  
The Face ◽  
Family Contact

A case of whooping cough in a moderate form in a child of the first month of life is described in the presented clinical observation. The moderate form was manifested by the duration of the preconvulsive period up to 5 days, the appearance of cyanosis of the face when coughing in the early stages of the disease (1 week), an increase in the number of coughing attacks. The difficulties of treating pertussis in young children are demonstrated by our observation of the course of the disease. There is no vaccination against pertussis in children in the family due to the refusal of parents and children with prolonged coughing were not examined at the outpatient stage. As a result, chemoprophylaxis was not performed on time and the newborn was discharged from the hospital to the center of pertussis infection. The solution to the problem of reducing the incidence in children in the first months of life should be vaccination of pregnant women in the last stages, and vaccination of the environment, including agerelated revaccinations. 

scholarly journals The role of tourism awareness in developing accessible tourism

2020 ◽  
pp. 437-463
Author(s):  
طه مهدي محمود ◽  
حسين محمد علي أسد
Keyword(s):  
Young Children ◽  
Pregnant Women ◽  
Special Needs ◽  
The Elderly ◽  
Tourism Industry ◽  
Negative Effects ◽  
High Quality ◽  
Tourism Sector ◽  
Effective Contribution

Tourism awareness is one of the most important pillars that contribute to the development of the tourism industry in general, and the development of various tourism patterns in particular, and among those patterns are accessible tourism, because of its great importance in reducing the negative effects that may accompany the tourism industry by building educated tourism employees And be aware, knowledgeable and aware of the importance of the accomplishments and successes achieved by the tourism sector and the opportunities that this sector offers and economic opportunities that ultimately reflect on the members of society and the country. Perhaps the sensitivity of dealing with the categories of accessible tourism (those with special needs, the elderly, pregnant women, mothers for young children) need special type employees who possess a set of special skills and experiences in dealing with those groups to make the details of the tourist trip for the concerned individuals, the most important of which is accommodation (the hotel). And to achieve the best possibility to enjoy the tourist activity in general. This research aims to highlight on the role of tourism awareness for a sample of employees of the holy Karbala hotels and their effective contribution to achieve the development of soft tourism by providing high-quality services that reassure the targeted tourists and thus contribute to attract the largest number of them, which is greatly reflected in the development of tourism and making years Coming golden years for this tourist pattern, which is considered an ethical and human duty to care about and develop.

scholarly journals Determining the Actual Zinc and Iron Intakes in Breastfed Infants: Protocol for a Longitudinal Observational Study

10.2196/19119 ◽  
2020 ◽  
Vol 9 (11) ◽  
pp. e19119
Author(s):  
Oraporn Dumrongwongsiri ◽  
Pattanee Winichagoon ◽  
Nalinee Chongviriyaphan ◽  
Umaporn Suthutvoravut ◽  
Veit Grote ◽  
...  
Keyword(s):  
Breast Milk ◽  
Pregnant Women ◽  
Iron Status ◽  
Deuterium Oxide ◽  
Nutrient Status ◽  
Dietary Intakes ◽  
Breastfed Infants ◽  
Milk Samples ◽  
Longitudinal Observational Study

Background Zinc and iron deficiencies among breastfed infants during the first 6 months of life have been reported in previous studies. The amounts of zinc and iron intakes from breast milk are factors that contribute to the zinc and iron status of breastfed infants. Objective This study aims to quantitatively determine zinc and iron intakes by breastfed infants during the first 4 months of life and to investigate the factors that predict zinc and iron status in breastfed infants. Methods Pregnant women at 28 to 34 weeks of gestation were enrolled. Zinc and iron status during pregnancy was assessed. At delivery, cord blood was analyzed for zinc and iron levels. Participants and their babies were followed at 2 and 4 months postpartum. Maternal dietary intakes and anthropometric measurements were performed. The amount of breast milk intake was assessed using the deuterium oxide dose-to-mother technique. Breast milk samples were collected for determination of zinc and iron levels. The amount of zinc and iron consumed by infants was calculated. Zinc and iron status was determined in mothers and infants at 4 months postpartum. Results A total of 120 pregnant women were enrolled, and 80 mother-infant pairs completed the study (56 provided full breastfeeding, and 24 provided breast milk with infant formula). All data are being managed and cleaned. Statistical analysis will be done. Conclusions This study will provide information on zinc and iron intakes in exclusively breastfed infants during the first 4 months of life and explore predictive factors and the possible association of zinc and iron intakes with infant growth and nutrient status. International Registered Report Identifier (IRRID) DERR1-10.2196/19119

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