scholarly journals Thoughtful surgical practice for therapeutic self: A randomized control trial

2020 ◽  
Vol 36 (7) ◽  
Author(s):  
Tausief Fatima ◽  
Dr. Rehan Ahmed Khan ◽  
Faryal Azher ◽  
Usman Mahboob
Keyword(s):  
Randomized Control Trial ◽  
Retention Rate ◽  
Surgical Skills ◽  
T Test ◽  
Surgical Practice ◽  
Equality Of Means ◽  
Significant Difference ◽  
Reflective Capacity ◽  
Randomized Control ◽  
One Way Anova

Objectives: To determine the role of structured reflection in teaching basic surgical skills in undergraduate students. Methods: A randomized control trial was done in two medical colleges of Punjab, from January to December 2017 in which participants were divided into two groups through stratified random sampling. Structured reflection was done by interventional group after training. Post-test was taken to assess their surgical skills. Independent t-test compared the mean of two groups. One-way ANOVA was calculated to measure the difference within the different sub-categories of experimental group. Results: Out of 140 students that participated in the study, 138 students stayed till the end (retention rate 98.5%, attrition rate 1.5%). Independent t-test (p-value = 0.01) showed statistically significant difference in both control and interventional groups. One-way ANOVA with robust test of equality of Means showed a positive relationship of reflective capacity and acquisition of surgical skills. Conclusion: The novices who demonstrates better reflective capacity exhibit better acquisition of surgical skills. doi: https://doi.org/10.12669/pjms.36.7.3038 How to cite this:Fatima T, Khan RA, Azhar F, Mahboob U. Thoughtful surgical practice for therapeutic self: A randomized control trial. Pak J Med Sci. 2020;36(7):---------. doi: https://doi.org/10.12669/pjms.36.7.3038 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

scholarly journals Perbandingan Efektivitas Anestesi Spinal dengan Bupivacain 12,5 Mg dan Bupivacain 5 Mg yang ditambah Fentanyl 50 Mcg pada Seksio Sesarea

2021 ◽  
Vol 4 (1) ◽  
pp. 11-7
Author(s):  
Fritzky Indradata ◽  
Heri Dwi Purnomo ◽  
Muh. Husni Thamrin ◽  
Sugeng Budi Santoso ◽  
Ardana Tri Arianto ◽  
...  
Keyword(s):  
Side Effects ◽  
Cesarean Section ◽  
Spinal Anesthesia ◽  
Randomized Control Trial ◽  
Hyperbaric Bupivacaine ◽  
Chi Square ◽  
Double Blind ◽  
Duration Of Action ◽  
Significant Difference ◽  
Randomized Control

Latar Belakang: Anestesi spinal mempunyai efek samping berupa hipotensi dan mual muntah. Tujuan: penelitian ini adalah membandingkan efek anestesi spinal bupivacain dosis normal 12,5 mg dan bupivacain dosis rendah 5 mg dengan fentanyl 50 mg pada seksio sesarea terhadap perubahan hemodinamik, ketinggian blok, onset, durasi dan efek samping. Subjek dan Metode: Penelitian double blind randomized control trial pada 36 pasien yang memenuhi kriteria. Pasien dibagi menjadi dua kelompok, yang masing-masing terdiri 18 pasien, kelompok 1 dilakukan anestesi spinal dengan bupivacain hiperbarik 5 mg ditambah adjuvan fentanyl 50 mcg, sedangkan kelompok 2 diberikan bupivacain hiperbarik 12,5 mg. Penilaian meliputi saat mula kerja blokade sensorik, mula kerja blokade motorik, durasi, tekanan darah, laju nadi, dan saturasi oksigen, lama kerja dan efek samping. Data hasil penelitian diuji secara statistik dengan uji chi-square. Hasil: Terdapat perbedaan signifikan pada onset dan durasi blokade sensorik dan motorik, bupivacain 12,5 mg lebih baik dibandingkan bupivacain 5 mg + fentanyl 50 mcg (p<0.05). Tidak ada perbedaan signifikan pada perubahan tanda vital dan efek samping (p>0.05). Simpulan: Bupivacain 12,5 mg menghasilkan onset lebih cepat dan durasi lebih lama dibandingkan bupivacain 5 mg + fentanil 50 mcg pada anestesi spinal untuk seksio sesarea   Comparison of The Effectiveness Spinal Anesthesia with Bupivacaine 12,5 Mg and Bupivacaine 5 Mg added Fentanyl 50 Mcg in Caesarean Section Abstract Background: Spinal anesthesia has side effects such as hypotension and nausea and vomiting. Objective: The aim of this study was to compare the effects of spinal anesthesia with normal doses of 12,5 mg of bupivacaine and 5 mg of low-dose bupivacaine with fentanyl 50 mg in the cesarean section on hemodynamic changes, block height, onset, duration, and side effects. Subjects and Methods: Double-blind randomized control trial in 36 patients who met the criteria. Patients were divided into two groups, each consisting of 18 patients, group 1 underwent spinal anesthesia with 5 mg of hyperbaric bupivacaine plus 50 mcg of fentanyl adjuvant, while group 2 was given 12,5 mg of hyperbaric bupivacaine. Assessments include the initiation of sensory block action, onset of motor block action, duration, blood pressure, pulse rate, and oxygen saturation, duration of action, and side effects. The research data were statistically tested with the chi-square test. Results: There were significant differences in the onset and duration of sensory and motor blockade, bupivacaine 12,5 mg was better than bupivacaine 5 mg + fentanyl 50 mcg (p <0.05). There was no significant difference in changes in vital signs and side effects (p> 0.05). Conclusion: Bupivacaine 12,5 mg resulted in a faster onset and longer duration than bupivacaine 5 mg + fentanyl 50 mcg in spinal anesthesia for cesarean section.

scholarly journals Evaluation of an Innovative Digital Assessment Tool in Dental Anatomy

2015 ◽  
Vol 16 (5) ◽  
pp. 366-371 ◽  
Author(s):  
Matt T Lam ◽  
So Ran Kwon ◽  
Fang Qian ◽  
Gerald E Denehy
Keyword(s):  
Gold Standard ◽  
Repeated Measures ◽  
Assessment Tool ◽  
T Test ◽  
Pearson’S Correlation ◽  
Digital Assessment ◽  
Dental Anatomy ◽  
Significant Difference ◽  
Pearson's Correlation ◽  
One Way Anova

ABSTRACT Aim The E4D Compare software is an innovative tool that provides immediate feedback to students’ projects and competencies. It should provide consistent scores even when different scanners are used which may have inherent subtle differences in calibration. This study aimed to evaluate potential discrepancies in evaluation using the E4D Compare software based on four different NEVO scanners in dental anatomy projects. Additionally, correlation between digital and visual scores was evaluated. Materials and methods Thirty-five projects of maxillary left central incisors were evaluated. Among these, thirty wax-ups were performed by four operators and five consisted of standard dentoform teeth. Five scores were obtained for each project: one from an instructor that visually graded the project and from four different NEVO scanners. A faculty involved in teaching the dental anatomy course blindly scored the 35 projects. One operator scanned all projects to four NEVO scanners (D4D Technologies, Richardson, TX, USA). The images were aligned to the gold standard, and tolerance set at 0.3 mm to generate a score. The score reflected percentage match between the project and the gold standard. One-way ANOVA with repeated measures was used to determine whether there was a significant difference in scores among the four NEVO scanners. Paired-sample t-test was used to detect any difference between visual scores and the average scores of the four NEVO scanners. Pearson's correlation test was used to assess the relationship between visual and average scores of NEVO scanners. Results There was no significant difference in mean scores among four different NEVO scanners [F(3, 102) = 2.27, p = 0.0852 one-way ANOVA with repeated measures]. Moreover, the data provided strong evidence that a significant difference existed between visual and digital scores (p = 0.0217; a pairedsample t-test). Mean visual scores were significantly lower than digital scores (72.4 vs 75.1). Pearson's correlation coefficient of 0.85 indicated a strong correlation between visual and digital scores (p < 0.0001). Conclusion The E4D Compare software provides consistent scores even when different scanners are used and correlates well with visual scores. Clinical significance The use of innovative digital assessment tools in dental education is promising with the E4D Compare software correlating well with visual scores and providing consistent scores even when different scanners are used. How to cite this article Lam MT, Kwon SR, Qian F, Denehy GE. Evaluation of an Innovative Digital Assessment Tool in Dental Anatomy. J Contemp Dent Pract 2015;16(5):366-371.

scholarly journals PENGARUH PELATIHAN SINGLE LEG SPEED HOP DAN DOUBLE LEG SPEED HOP TERHADAP DAYA LEDAK OTOT TUNGKAI

2018 ◽  
Vol 6 (3) ◽  
Author(s):  
Ni Kadek Risna Dewi ◽  
I Ketut Sudiana ◽  
Ni Luh Kadek Alit Arsani
Keyword(s):  
Random Sampling ◽  
Vertical Jump ◽  
Simple Random Sampling ◽  
T Test ◽  
Mean Difference ◽  
Control Groups ◽  
Jump Test ◽  
Significant Difference ◽  
Leg Muscle ◽  
One Way Anova

Penelitian ini bertujuan untuk mengetahui pengaruh pelatihan single leg speed hop dan double leg speed hop terhadap peningkatan daya ledak otot tungkai. Jenis penelitian ini adalah penelitian eksperimen sungguhan dengan rancangan the randomized pretest posttest control groups design. Sampel penelitian ini adalah siswa putri SMP N 3 Mengwi sebanyak 45 orang ditentukan dengan teknik simple random sampling. Daya ledak otot tungkai diukur dengan vertical jump test dan data dianalisis dengan uji t independent, uji anava satu jalur dan dilanjutkan dengan uji least significant difference (LSD) pada taraf signifikansi (α) 0,05 dengan bantuan komputer program SPSS 16,0. Berdasarkan uji t independent pada pelatihan single leg speed hop diperoleh nilai sebesar 4,987 dengan nilai signifikansi sebesar 0,000 sedangkan pada pelatihan double leg speed hop diperoleh nilai sebesar 2,509 dengan nilai signifikansi sebesar 0,018. Berdasarkan uji anava satu jalur diperoleh nilai sebesar 11,695 dengan nilai signifikansi sebesar 0,000 dan uji least significant difference (LSD) menunjukkan bahwa terdapat perbedaan pengaruh antara kedua pelatihan dan pelatihan single leg speed hop mempunyai pengaruh yang lebih baik dari pelatihan double leg speed hop dengan mean difference sebesar 4,667. Dari hasil penelitian, dapat disimpulkan bahwa pelatihan single leg speed hop dan double leg speed hop berpengaruh terhadap peningkatan daya ledak otot tungkai pada siswa putri SMP N 3 Mengwi tahun pelajaran 2013/2014 dan terdapat perbedaan pengaruh antara kedua pelatihan serta pelatihan single leg speed hop mempunyai pengaruh yang lebih baik dari pelatihan double leg speed hop. Kata Kunci : pelatihan single leg speed hop, pelatihan double leg speed hop, daya ledak otot tungkai. This research aimed to determine the effect of speed single leg speed hop and double leg speed hop training in improving power of leg muscle. This research was a true experiment by the randomized pretest posttest control groups design. The sample was students of SMP N 3 Mengwi daughter as many as 45 people were determined by simple random sampling. Power of leg muscle was measured by vertical jump test and data were analyzed by independent t-test, one way anova and least significant difference (LSD) with significance level (α) 0,05 using computer program SPSS 16.0. Based on independent t-test on single leg speed hop training obtained 4.987 with a significance value of 0.000, while the double-leg speed hop training obtained 2.509 with a significance value of 0.018. Based on one way anova of the obtained value of F 11.695 with a significance value of 0.000 and the least significant difference test (LSD) showed there was a different effect between the two types of training and single leg speed hop training has better effect than double leg speed hop training with mean difference of 4.667. From the results, it could be concluded that single leg speed hop and double leg speed hop training were effective to improve power of leg muscle on the students of SMP N 3 Mengwi daughter of the school year 2013/2014 and there was a different effect between the two types of training and single leg speed hop training have a better effect than double leg speed hops training.keyword : single leg speed hop training, double leg speed hop training, power of leg muscle.

Effects of thoracic spine manipulation on pressure pain sensitivity of rhomboid muscle active trigger points: a randomized control trial

2021 ◽  
pp. 1-12
Author(s):  
Bibi Haleema ◽  
Huma Riaz
Keyword(s):  
Thoracic Spine ◽  
Randomized Control Trial ◽  
Rating Scale ◽  
Trigger Points ◽  
Control Group ◽  
Pressure Sensitivity ◽  
Myofascial Trigger Points ◽  
Pain Pressure Threshold ◽  
Significant Difference ◽  
Randomized Control

Abstract Objective: The objective of study was to determine the effects of thoracic spine manipulation on interscapular pain and pain pressure sensitivity, thoracic mobility and disability due to active myofascial trigger points in rhomboid muscle. Methods: A randomized control trial was conducted at Women Institute of Rehabilitation Sciences Abbottabad, from July to December 2019.Ethical permission was taken fromResearch ethical committee of Riphah international university Islamabad. Participants were selected through non-probability purposive sampling technique as per inclusion criteria. It consisted of 60 participants with forward head posture having active trigger points in rhomboid muscle, with age ranging from 18 to 30 years. The participants were randomly allocated through sealed envelope method into two groups that are experimental and control. Experimental group has received thoracic manipulation along with conventional physical therapy (CPT) whereas control group has only received CPT including manual pressure release and therapeutic exercise. Intervention was applied with 2 sessions / week with 3 weeks in total. Pre and Post assessment was done with outcome measurement tools comprised of Numeric pain rating scale (NPRS) for pain severity, Algometry for pain pressure threshold(PPT), Inclinometer for Range of movement(ROM) and Neck disability index (NDI) for associated disability. Data analysis was done using SPSS-20 version. Results: Between group analysis has shown significant improvement of pain & pain pressure sensitivity with p value <0.01 and <0.05 respectively. All outcome measures have shown significant difference in pre post treatment (p<.000) in both groups. Continuous...

scholarly journals EFEKTIFITAS SUPLEMENTASI FERRO SULFAT (FE) DALAM MENINGKATKAN KADAR FERRITIN PADA IBU HAMIL TRIMESTER I

2019 ◽  
Vol 14 (4) ◽  
pp. 301
Author(s):  
Isfaizah Isfaizah ◽  
Cahyaningrum Cahyaningrum
Keyword(s):  
World Bank ◽  
Randomized Control Trial ◽  
T Test ◽  
Post Test ◽  
Randomized Control

Latar Belakang: Anemia menjadi salah satu masalah gizi yang penting pada ibu hamil, dimana menurut World Bank (2011) prevalensi anemia di Indonesia sebesar 30% dan anemia menyebabkan 40% kematian ibu. Komplikasi anemia kehamilan adalah kematian janin, abortus, cacat bawaan dan berat badan lahir rendah. Suplementasi ferro sulfat sangat penting untuk meningkatkan konsentrasi hemoglobin dan konsentrasi ferritin.Tujuan: Penelitian ini bertujuan untuk mengetahui efektifitas suplementasi ferro sulfat (fe) dalam meningkatkan kadar ferritn pada ibu hamil trimester I.Metode: Penelitian ini merupakan penelitian Randomized Control Trial (RCT)dengan rancangan One Group Pre-test and Post-test Desain. Subjek penelitian ini adalah seluruh ibu hamil trimester I yang berada di wilayah kerja Puskesmas Ungaran dengan pendekatan fixed desease sampling. Sebanyak 12 responden ibu hamil trimester I mendapatkan suplementasi ferro sulfat selama 3 bulan. Pengumpulan data menggunakan kuesioner, pengukuran kadar hemoglobin (Hb) menggunakan Digital Hb Easy Touch, dan pengukuran kadar ferritin menggunakan metode ECLIA. Analisis data menggunakan uji t test-dependent dengan SPSS Versi 22. Hasil: Rerata kadar Hb pre 11.07±1.84, rerata kadar ferritin pre 66.28±34.01, rerata kadar Hb post 10.29±1.74, rerata kadar ferritin post 35.95±18.43. Tidak terdapat perbedaan kadar Hb sebelum dan sesudah diberikan suplementasi Fe (p = 0.209) dan terdapat perbedaan kadar ferritin sebelum dan sesudah diberikan suplementasi Fe (p = 0.008) pada ibu hamil Trimester I. Kesimpulan: Suplementasi fe pada ibu hamil Trimester I tidak berpengaruh dalam perubahan kadar hemoglobin, tetapi berpengaruh pada perubahan kadar ferritin.Perlu keteraturan dalam meminum Fe dan asupan makanan yang tinggi Fe membantu absorbsi Fe pada ibu hamil.

scholarly journals In vitro study of marginal, internal and proximal adaptation of implant-supported single-crown CAD/CAM restorations

2020 ◽  
Vol 19 ◽  
pp. e207286
Author(s):  
Kamila Aguiar Figueiredo Alves ◽  
Janaina Emanuela Damasceno ◽  
Viviane Maia Barreto de Oliveira ◽  
Luiz Gustavo Cavalcanti Bastos ◽  
Andrea Nóbrega Cavalcanti
Keyword(s):  
Repeated Measures ◽  
T Test ◽  
Digital Impression ◽  
Single Crown ◽  
Significant Difference ◽  
Cad Cam ◽  
Student’S T ◽  
One Way Anova ◽  
Student’S T Test

Aim: This study evaluated the precision of a CAD/CAM system by measuring marginal, internal and proximal fits in implantsupported single-crown restorations. Methods: Ten models of the upper arch were made in which implants replaced the upper left premolars. For fabrication of the zirconia infrastructures, titanium bases (TiBase) were coded and scanned using a scan body. A second digital impression was made for the fabrication of prostheses. Silicone impression material was used to determine the internal clearance between the TiBase and infrastructure and between the infrastructure and crown, whose thickness was measured at three points [P1 (cervical), P2 (middle) and P3 (occlusal)] with a stereoscopic microscope at 70x and 100x magnification. One-way ANOVA for repeated measures and the Student t-test were used for the analysis of internal and marginal adaptation. Proximal contacts were analyzed qualitatively. Results: There was no significant difference between the teeth evaluated (Student’s t-test; p>0.05) or between the corresponding points evaluated in either tooth (one-way ANOVA; p>0.05). Analysis of the internal clearance between the infrastructure and crown demonstrated that all points were significantly different compared to the reference standardized at 100 μm (Student’s t-test p<0.0001). There was no significant difference between P1 and P2, with the thickness at these two points being lower than that obtained at P3 (one-way ANOVA, p<0.05). The proximal contacts did not coincide with the quality defined by the device. Conclusion: The system tested was unable to produce implantsupported single-crown ceramic restorations with marginal, internal and proximal fits matching the digital workflow, with the inferior fits requiring adjustment prior to cementation.

scholarly journals Correlation of frankfort horizontal with the sellanasion line angular data in different sagittal skeletal bases

2020 ◽  
Vol 16 (12) ◽  
pp. 1088-1093
Author(s):  
Mathew Thomas Maliael ◽  
Keyword(s):  
T Test ◽  
Class I ◽  
Gender Dimorphism ◽  
Skeletal Class ◽  
Significant Difference ◽  
Beta Angle ◽  
Angular Data ◽  
The Difference ◽  
The One ◽  
One Way Anova

It is of interest to establish the cephalometric correlation of angular data between frankfort horizontal and the sella-nasion line in different sagittal skeletal bases. Beta angle was used to divide the sample based on their sagittal skeletal base relationship. The FH-SN angle was measured for each group. The data were tabulated into IBM SPSS software. Kolmogorov-Smirnov and Shapiro-Wilk test was done to test the normal distribution of the data. One-way ANOVA analysis was done to test the difference of the FH-SN angle among the groups. Independent samples t-Test was done to test for gender dimorphism. The mean FH-SN angle of the sample was 6.33°3.35°. The results of the One-Way ANOVA and independent samples t-Test were insignificant. Results show that is no statistically significant difference in FHSN angle between skeletal class I, II and III.The mean FH-SN angle of the sample was 6.33°3.35°. The distribution of the data was normal. The results of the One-Way ANOVA and Independent samples t-Test were insignificant. There was no statistically significant difference in FH-SN angle between skeletal class I, II and III.

scholarly journals Pengaruh Metode PETTLEP dan Media Audio Visual Terhadap Hasil Belajar Keterampilan Jurus Tunggal Baku Pencak Silat

2019 ◽  
Vol 4 (2) ◽  
pp. 107-116
Author(s):  
Oktoviana Nur Ajid ◽  
Komarudin Komarudin ◽  
Mulyana Mulyana
Keyword(s):  
Visual Media ◽  
T Test ◽  
Control Group ◽  
Training Experience ◽  
Control Group Design ◽  
Study Program ◽  
Sports Science ◽  
Significant Difference ◽  
Experiment Method ◽  
One Way Anova

Abstract Tujuan penelitian ini untuk melihat pengaruh metode PETTLEP dan media audio visual terhadap pembelajaran jurus tunggal baku pencak silat. Sampel dalam penelitian ini adalah tiga puluh pesilat pemula yaitu mahasiswa program studi ilmu keolahragaan FPOK UPI dengan pengalaman latihan 2 bulan. Metode yang digunakan eksperimen dengan desain the randomized pretest posttest control grup. Analisis data menggunakan SPSS versi 23 dengan pengujian hipotesis melalui independent sample t test dan one way anova. Hasil analisis dan perhitungan data mengungkapkan bahwa 1) Terdapat pengaruh metode PETTLEP terhadap hasil belajar keterampilan jurus tunggal baku pencak silat 2) Terdapat pengaruh media audio visual terhadap hasil belajar keterampilan jurus tunggal baku pencak silat 3) Terdapat pengaruh metode demonstrasi terhadap hasil belajar keterampilan jurus tunggal baku pencak silat 4) Terdapat perbedaan yang signifikan antara metode PETTLEP, media audio visual, dan metode demonstrasi terhadap hasil belajar keterampilan jurus tunggal baku pencak silat.. Abstract The purpose of this study was to see the effect of the PETTLEP method and audio-visual media on learning of the jurus tunggal baku of Pencak Silat. The sample in this study was thirty beginner martial artists which are the students of FPOK UPI Sports Science Study Program with 2 months training experience. Experiment method was conducted with the randomized pretest posttest control group design. The data was analyzed using SPSS version 23 by testing hypotheses through independent sample t test and one-way ANOVA. The results of the analysis and calculation of the data revealed that 1) There is an effect of the PETTLEP method on the learning outcomes of the jurus tunggal baku of pencak silat 2) There is an effect of the audiovisual media on the results of the learning skills of the jurus tunggal baku of Pencak Silat 3) There is an effect of the demonstration method on the learning outcome of the jurus tunggal baku of Pencak Silat 4) There is a significant difference between the PETTLEP method, audio visual media, and the demonstration method towards the results of learning the skills of a jurus tunggal baku of Pencak Silat. 

scholarly journals Assessment of effectiveness of an interventional package on treatment adherence of hypertensive patients: a randomized control trial

2021 ◽  
Vol 8 (6) ◽  
pp. 2862
Author(s):  
Kmendalin Nongspung ◽  
Kavita Narang ◽  
J. S. Thakur
Keyword(s):  
Blood Pressure ◽  
Treatment Adherence ◽  
Randomized Control Trial ◽  
T Test ◽  
Control Group ◽  
Sampling Frame ◽  
Strict Adherence ◽  
Hypertensive Patients ◽  
Randomized Control ◽  
Experimental Group

Background: Hypertension is the most common non-communicable diseases. Strict adherence to prescribed antihypertensive treatments is the key to blood pressure control. The present study was conducted with the objective to develop, implement and assess an interventional package on treatment adherence for hypertensive patients.Methods: A clustered randomized control trial of 3 months conducted in two community sites of Chandigarh. The two sites were first randomized by lottery method as experimental and control sites. Total of 250 subjects (n=125 on each sites) were selected by a systematic random sampling technique (every fourth) from the sampling frame. Diagnosed hypertensive patients taking treatment were included in the study and females with pregnancy induced hypertension were excluded. Participants were interviewed as per Interview schedule. Data was collected from July to November 2018. Interventional package was in the form of booklet and flash card, delivered as one to one teachings. Total of 5 face to face follow ups were done to the experimental group. Control group received routine care. Final evaluation was done at 3rd month in both the groups to assess the effectiveness of an interventional package on treatment adherence. Data analysis and interpretation was done by using chi square, paired t test, unpaired t- test, Mc Nemar test were applied to determine the level of significance at p<0.05.Results: The proportion of subjects who were adhered to the treatment has increased from 16% to 68% in the experimental group at third month of follow up. The mean change in systolic blood pressure and diastolic blood pressure were 26.29±12.81 mmHg and 7.74±8.95 mmHg respectively in the experimental group as compared to the control group (p<0.05).Conclusions: The interventional package on treatment adherence among hypertensive patients was effective in improving the treatment adherence.

scholarly journals 73 The Use of Topical Anaesthetic in The Banding of Internal Haemorrhoids: A Feasibility Study for A Randomized Control Trial

2021 ◽  
Vol 108 (Supplement_6) ◽  
Author(s):  
V Sharma ◽  
D Sharma ◽  
A Stearns ◽  
J Hernon
Keyword(s):  
Outcome Measures ◽  
Randomized Control Trial ◽  
Recruitment Rate ◽  
Phase Iii ◽  
Feasibility Trial ◽  
Secondary Outcome ◽  
Topical Anaesthetic ◽  
Pain Scores ◽  
Significant Difference ◽  
Randomized Control

Abstract Aim Rubber band ligation (RBL) is a procedure commonly performed in colorectal clinics for internal haemorrhoids. 90% of patients experience pain following RBL. We aimed to complete a feasibility randomized control trial assessing the role of topical anaesthetic before RBL of internal haemorrhoids. Method We performed a prospective, single-centre, single blinded, randomized(1:1) controlled feasibility trial. Patients presenting with symptomatic haemorrhoids suitable for banding were randomized to undergo the procedure with local anaesthetic or without(control). Pain scores and vasovagal symptoms were assessed at 0 minutes, 30minutes, 4 hours, and 72 hours after the procedure. Primary outcome measures were recruitment rate, participant retention rate, patient and surgeon acceptability. Secondary outcome measures were pain scores up to 72 hours, vasovagal episodes, new use of analgesia, and adverse outcomes. Results 35 patients (18 topical anaesthetic, group A; 17 no anaesthetic gel, group B) were recruited. Mean recruitment rate was 11.7 participants per month. 33(94%) participants remained in the study until completion, with 2 patients lost to telephone follow-up. The treatment was acceptable for 35(97%) eligible patients. 1 patient declined enrolment. The treatment was acceptable to all surgeons (100%). There was a significant difference in median pain scores of -2(95% CI -4.0 to -1.0, p = 0.0006) at the 30-minute time point only. There was no significant difference in vasovagal symptoms(p = 0.10) or new analgesia use(p = 0.85). Conclusions In conclusion, we have shown that a phase III clinical trial is feasible. We have demonstrated excellent patient recruitment and retention as well as patient and surgeon acceptability.

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