Biophysical models of pathological and postural tremor

2015 ◽  
Vol 9 (4) ◽  
pp. 0-0
Author(s):  
Полухин ◽  
V. Polukhin ◽  
Берестин ◽  
D. Berestin ◽  
Филатова ◽  
...  
Keyword(s):  
Physiological State ◽  
Chaotic Regime ◽  
Wilcoxon Test ◽  
Phase Matching ◽  
Autocorrelation Functions ◽  
Biophysical Models ◽  
Sequential Measurement ◽  
Significant Difference ◽  
The Subject ◽  
New Criteria

Real chaotic and stochastic analysis of the two movements (tremor was considered as involuntary movements and tapping - arbitrary) shows them as chaotic movements (involuntary on the results of the test, not by the presence of the target). The authors introduce new criteria for separating these two types of motion in the form of matrices of pairwise comparisons of samples tremorograms and tappingrams. Identifying differences between the concrete (obtained continuously, during the sequential measurement) that are compared in pairs in one subject groups was performed using the Wilcoxon test. The increase in the number of "common" pairs of samples of tappingrams compared to tremorograms demonstrates a partial increase of phase-matching due to the afferentation and engaging mental activity. This indicates the beginning of a shift from the chaotic regime to stochastic. The increase in common pairs of tapping may be possible due to the change in patterns of fluctuations. The authors propose a new calculation of quasi-attractors of these two types of movements that allow the identification of the differences in the physiological state of the subject. The concrete examples of the changes in the parameters of the matrices of paired comparisons and quasi-attractors are demonstrated. The authors present a method of analysis of autocorrelation functions when partitioning the interval (-1; 1) into four parts. Using the analysis of the density autocorrelation functions and tremorograms and tappingrams shows a significant difference between involuntary movements (tremor) and arbitrary movement (tapping).

scholarly journals ENTREPRENEURSHIP EDUCATION TO IMPROVE ENTREPRENEURSHIP INTENTION

2019 ◽  
Vol 7 (3) ◽  
pp. 162-168
Author(s):  
Fatwa Tentama ◽  
Surahma Asti Mulasari ◽  
Subardjo . ◽  
Santi Widiasari
Keyword(s):  
Data Analysis ◽  
Sampling Technique ◽  
Entrepreneurship Education ◽  
Wilcoxon Test ◽  
Purposive Sampling ◽  
Data Analysis Technique ◽  
Analysis Technique ◽  
Significant Difference ◽  
Before And After ◽  
The Subject

Purpose: This research aims at finding out the effect of entrepreneurship education on people’s entrepreneurship intention. Methodology: The subject of the research includes 18 persons of Wedomartani village, Sleman regency, Yogyakarta with the characteristics of having no jobs, having been married, and male or female incapable of handling waste for entrepreneurship. The sampling technique uses purposive sampling. The data analysis technique uses a Wilcoxon test. Results: The result of the analysis is Z = -2.102 and p = 0.018 (1-tailed), with p<0.05, which means there is a significant difference between the people's entrepreneurship intention before and after entrepreneurship education. So entrepreneurship education is effective in improving the people's entrepreneurship intention. Implications: People’s intention to convert waste into marketable goods is still low so that the waste spoils the environment. Therefore, entrepreneurship education is needed to rouse their intention in doing it.

Mathematical modeling of involuntary movements in health and disease

2015 ◽  
Vol 4 (2) ◽  
pp. 75-86
Author(s):  
Дерпак ◽  
V. Derpak ◽  
Полухин ◽  
V. Polukhin ◽  
Еськов ◽  
...  
Keyword(s):  
Mathematical Modeling ◽  
Physiological State ◽  
Paired Comparisons ◽  
Postural Tremor ◽  
Model Data ◽  
Final Test ◽  
Involuntary Movements ◽  
Health And Disease ◽  
The Subject ◽  
New Criteria

The problem of voluntary or involuntary movements are discussed more than 150 years. Traditionally, the tremor was considered involuntary movements and tapping - arbitrary. Real stochastic and chaotic analysis of these two types of motion shows them as chaotic motion (involuntary as a result of the test, rather than by the presence of the target). Introduced new criteria for the separation of these two types of motion in the form of paired comparisons matrix samples tremorogramm and teppingramm. Models of the evolution of the tremor in the mode of the three transitions: normal postural tremor, tremor in Parkinson´s disease and the transition to a rigid form of the disease. A comparison of model data and observations on patients. In addition, it is proposed dimensioning of quasi-attractors of these two types of movements, which provide the identification of differences of physiological state of the subject. Demonstrated specific examples of parameters matrix of paired comparisons and quasi-attractors while perturbation the final test.

SENSITIVITAS ETIS MAHASISWA ATAS PENGGELAPAN PAJAK

2017 ◽  
Vol 8 (2) ◽  
pp. 178-195
Author(s):  
Nurma Risa
Keyword(s):  
Tax Evasion ◽  
Female Students ◽  
T Test ◽  
Study Program ◽  
Male And Female ◽  
Political Sciences ◽  
Significant Difference ◽  
The Subject ◽  
And Gender ◽  
Management Students

This study aims to prove that there is a difference of perception about ethics on tax evasion in UNISMA Bekasi students, based on selected study program and gender. The sample of this research is the students who have fulfilled the subject of taxation, at the Faculty of Economics (FE) and Faculty of Social and Political Sciences (FISIP). Using independent t-test, the results showed that there was no significant difference of perception about tax evasion ethics between FE and FISIP students. But significant differences the perception of tax evasion ethics occur between accounting and management students at FE. Significant differences also did not occur between male and female students

Analisis Perbedaan Prestasi Belajar Mahasiswa Fakultas Tarbiyah Dan Ilmu Keguruan (Ftik) Iain Palu Pada Mata Kuliah Evaluasi Pembelajaran Berdasarkan Gender

2019 ◽  
Vol 9 (1) ◽  
pp. 152-190
Author(s):  
Wiwin Mistiani
Keyword(s):  
Student Achievement ◽  
Sampling Technique ◽  
Female Students ◽  
Male Students ◽  
Error Level ◽  
Learning Achievement ◽  
Learning Evaluation ◽  
Significant Difference ◽  
The Subject ◽  
Evaluation Of Learning

This study aims to determine the student achievement of male and female students on the subyek Evaluation of learning and to determine of Differences in student achievement FTIK IAIN Palu on the subject evaluastion learning by gender. The approach used is descriptive quantitative. While the population in this study are all students. The sampling technique is done by using proportional random sampling technique. With the number of students 60 people then the sample = 37 students of FTIK IAIN Palu. Technique of collecting data by using test and observation while data analysis using T test.From the research, 1) the average of learning achievement in the subject of male students' learning appraisal from 19 male students who are the sample in this research is 79,42 means good category. Meanwhile, from 18 female students who became the sample of the study, the average of learning achievement in the subject of female students' learning evaluation is 77 means either. 2) There is no significant difference Student Learning Achievement FTIK) IAIN Palu On the subject Evaluation Learning Based on Gender with t value equal to = 0,0267 with t table with dk 35 with error level 5% is 0,062.

Effectiveness Of Toilet Training Education On Mother's Behavior And Toddler Age Toilet Training Ability (18-36 Months)

2020 ◽  
Vol 5 (2) ◽  
pp. 49-55
Author(s):  
Hafiko Andresni ◽  
Zahtamal Zahtamal ◽  
Winda Septiani ◽  
Mitra Mitra ◽  
Lita Lita
Keyword(s):  
Sampling Technique ◽  
T Test ◽  
The Body ◽  
Toilet Training ◽  
Wilcoxon Test ◽  
Control Group ◽  
Maternal Knowledge ◽  
Control Group Design ◽  
Significant Difference

ABSTRACT Toilet training is an effort to train children to be able to control and urinate (BAK) and defecate (BAB). Toilet training is one of the main tasks of children at toddler age. Toilet training is one of the main tasks of children in toddler age which is very important to be done to create independence in children in controlling BAK and BAB and children know the parts of the body and their functions. Data in 2012 shows that ± 60% of parents do not teach toilet training to children from an early age. The aim of the study was to find out the effectiveness of toilet training education on maternal behavior and toilet skills in toddler age training (18-36 months). The study was conducted in July-August 2018. This type of quantitative research used the design of the Quasy pretest and posttest experiment with non-equivalent control group design. Samples were 36 mothers and 36 children with purposive sampling technique. Data analysis used Paired t test, Wilcoxon test, Man-Whitney test an Independent t test. The results showed that toilet training education through lecture methods, modules and maze games was more effective than toilet training education through lecture and leaflet methods on children's knowledge and abilities. Conversely, for the role of mothers in supervision there is no significant difference in effectiveness. Health education is recommended in health promotion programs to increase maternal knowledge, the role of mothers and the ability of toilet training children independently. Keywords: Toilet training, Lecture method, Module, Maze game, Leaflet, Knowledge, Role of mother, Children's ability.

Effect of Nada Yoga on Hypertension & Anxiety Level

GIS Business ◽  
2019 ◽  
Vol 14 (6) ◽  
pp. 1-16
Author(s):  
Naveen Kumar ◽  
Kuldeep singh
Keyword(s):  
Sound Speed ◽  
Anxiety Level ◽  
Hatha Yoga ◽  
Significant Difference ◽  
The Subject ◽  
Level Of Significance

In Nada yoga the sound speed of an object vibrates (as well as its size, however infinitesimal) contributes to its particular sound. Different tone and frequencies contains the subject of meditation in Nada Yoga, which also takes into consideration the musical intervals used in music and in the musical recitation of mantras, is brought together with meditation techniques and certain Hatha Yoga practices that are conducive to sonic exploration. Recently a study conducted on anxiety and hypertension level in Raigarh entitled as “The effect of Nada Yoga on Hypertension and anxiety level”.  The outcome of the study shows that Nada Yoga significantly reduces Anxiety as well as Hypertension. Results founds were surprisingly shows a significant difference between the two means, at .01 level of significance. It shows how Nada Yoga can effectively help to reduce anxiety and hypertension as well as many improves in health also.

scholarly journals Can the cytokine adsorber CytoSorb® help to mitigate cytokine storm and reduce mortality in critically ill patients? A propensity score matching analysis

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Christina Scharf ◽  
Ines Schroeder ◽  
Michael Paal ◽  
Martin Winkels ◽  
Michael Irlbeck ◽  
...  
Keyword(s):  
Propensity Score ◽  
Critically Ill ◽  
Critically Ill Patients ◽  
Wilcoxon Test ◽  
Relative Reduction ◽  
Cytokine Storm ◽  
Saps Ii ◽  
Significant Difference ◽  
Group 2 ◽  
Group 1

Abstract Background A cytokine storm is life threatening for critically ill patients and is mainly caused by sepsis or severe trauma. In combination with supportive therapy, the cytokine adsorber Cytosorb® (CS) is increasingly used for the treatment of cytokine storm. However, it is questionable whether its use is actually beneficial in these patients. Methods Patients with an interleukin-6 (IL-6) > 10,000 pg/ml were retrospectively included between October 2014 and May 2020 and were divided into two groups (group 1: CS therapy; group 2: no CS therapy). Inclusion criteria were a regularly measured IL-6 and, for patients allocated to group 1, CS therapy for at least 90 min. A propensity score (PS) matching analysis with significant baseline differences as predictors (Simplified Acute Physiology Score (SAPS) II, extracorporeal membrane oxygenation, renal replacement therapy, IL-6, lactate and norepinephrine demand) was performed to compare both groups (adjustment tolerance: < 0.05; standardization tolerance: < 10%). U-test and Fisher’s-test were used for independent variables and the Wilcoxon test was used for dependent variables. Results In total, 143 patients were included in the initial evaluation (group 1: 38; group 2: 105). Nineteen comparable pairings could be formed (mean initial IL-6: 58,385 vs. 59,812 pg/ml; mean SAPS II: 77 vs. 75). There was a significant reduction in IL-6 in patients with (p < 0.001) and without CS treatment (p = 0.005). However, there was no significant difference (p = 0.708) in the median relative reduction in both groups (89% vs. 80%). Furthermore, there was no significant difference in the relative change in C-reactive protein, lactate, or norepinephrine demand in either group and the in-hospital mortality was similar between groups (73.7%). Conclusion Our study showed no difference in IL-6 reduction, hemodynamic stabilization, or mortality in patients with Cytosorb® treatment compared to a matched patient population.

scholarly journals Inhibition of Kynurenine Metabolism and Its Effect in Mitochondrial Function in Hepatocellular Carcinoma

2020 ◽  
Vol 4 (Supplement_1) ◽  
pp. 124-125
Author(s):  
Raul Castro-Portuguez ◽  
Samuel Freitas ◽  
George Sutphin
Keyword(s):  
Hepatocellular Carcinoma ◽  
Mitochondrial Function ◽  
De Novo ◽  
Principal Component ◽  
Kynurenine Pathway ◽  
The Cancer Genome Atlas ◽  
Wilcoxon Test ◽  
Nad Synthesis ◽  
Significant Difference ◽  
Kynurenine Metabolism

Abstract Hepatocellular carcinoma (HCC) is the most prevalent cancer in the liver. The majority of ingested tryptophan is processed in the liver through the kynurenine pathway, the endpoint of which is de novo NAD+ biosynthesis. Dysregulation of tryptophan-kynurenine metabolism and NAD+ synthesis may promote mitochondrial malfunction, tumor reprogramming, and carcinogenesis. Using a publicly available gene expression dataset from liver hepatocellular carcinoma (LIHC) samples available through The Cancer Genome Atlas (TCGA; n = 371), we employed Principal Component Analysis (PCA), hierarchical clustering, gene-pattern expression profiling, and survival analysis to cluster patients and determine overall survival. Our analysis of genes encoding kynurenine pathway enzymes determined that patients with high QPRT expression had a poor prognosis with decreased median survival, with no effect on the maximum survival. There is a significant difference in the survival between patients with high QPRT expression relative to patients with high HAAO/AFMID expression (HR = 1.2, [95% CI 0.5-1.8] P = 0.0181, Gehan-Breslow-Wilcoxon Test). Patients with high QPRT expression have higher survival rates compared with low QPRT expression (HR = 1.4, [95% CI 0.9-2.2] P = 0.0344, Gehan-Breslow-Wilcoxon Test). To test the consequences of kynurenine-pathway inhibition in mitochondrial function and morphology we use 4-Cl-3HAA, an irreversible HAAO inhibitor, and observed a small increase in mitochondrial fragmentation in HepG2 cells after 24 hours of treatment. We conclude that kynurenine metabolism may be useful as a biomarker to predict patient prognosis among HCC patients. In ongoing work, we are testing QPRT inhibitors in cell culture as a potential adjuvant for chemotherapies.

Speech Methodologies in Cleft Palate Assessment: A Pilot Project to Compare Two Phonetically Different Sentence Sets

2013 ◽  
Vol 20 (1) ◽  
pp. 49-72
Author(s):  
Jennie Smith ◽  
Tim Pring ◽  
Debbie Sell
Keyword(s):  
Cleft Palate ◽  
Pilot Project ◽  
Wilcoxon Test ◽  
Consecutive Series ◽  
Video Recordings ◽  
Significant Difference ◽  
The Difference ◽  
Audio Video ◽  
Age Range ◽  
The Impact

Objective: To investigate the impact of the phonetic content of two sentence sets on speech outcomes, specifically the effects of nasal phonemes. Method: Audio-video recordings of a consecutive series of 15 participants (age range 4–22 years), with cleft palate (syndromic or non-syndromic), with and without velopharyngeal dysfunction were taken. Participants repeated Sentence Set 1 (with nasals across sentences) and Sentence Set 2 (without nasals except the three nasal target sentences) during a routine speech recording. Two experienced Specialist Speech and Language Therapists, blinded to the study’s purpose, analyzed participants’ speech using the Cleft Audit Protocol for Speech-Augmented (CAPS-A). On day 1, recordings included Sentence Set 1. On day 2, 23 days later, recordings included Sentence Set 2. Main results: The difference between Sentence Set 1 and Sentence Set 2 ‘total scores’ (sum of scores on all CAPS-A parameters) was significant. The Pearson Product Moment showed high correlation. A Wilcoxon test revealed a significant difference between Sets 1 and 2 on the hypernasality parameter, and this alone accounted for the significant difference in total scores. Conclusion: The inclusion or exclusion of nasal consonants in the sentence set significantly affected perceptual ratings of hypernasality but none of the other CAPS-A parameters, highlighting the need for further investigation into perceptual nasality ratings.

scholarly journals Successful elimination of bilirubin in critically ill patients with acute liver dysfunction using a cytokine adsorber and albumin dialysis: a pilot study

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Christina Scharf ◽  
Uwe Liebchen ◽  
Michael Paal ◽  
Andrea Becker-Pennrich ◽  
Michael Irlbeck ◽  
...  
Keyword(s):  
Liver Dysfunction ◽  
Total Bilirubin ◽  
Wilcoxon Test ◽  
Organ Support ◽  
Relative Reduction ◽  
High Flux ◽  
Albumin Dialysis ◽  
Liver Support ◽  
Artificial Liver Support ◽  
Significant Difference

AbstractThere are different methods of artificial liver support for patients with acute liver dysfunction (ALD). However, CytoSorb (CS) might be a new approved option for those patients. Question of interest is whether the elimination performance of CS was comparable to that of advanced organ support (ADVOS). Patients, treated with CS (integrated into high-flux dialysis) or ADVOS and a total bilirubin > 10 mg/dl were included. Laboratory parameters were evaluated before starting therapy (d0) and 12–24 h thereafter (d1). The Wilcoxon-test with associated samples was used for statistical analysis. Thirty-nine patients (33 CS, 6 ADVOS) were included. The median bilirubin at d0 was 16.9 and 17.7 mg/dl and at d1 was 13.2 and 15.9 mg/dl, in the CS and ADVOS group, respectively. There was a significant bilirubin reduction as well in the CS group (p < 0.001, median relative reduction: 22.5%) as in the ADVOS group (p = 0.028, median relative reduction: 22.8%). There was no significant difference in the relative bilirubin reduction between CS and ADVOS therapies. The use of CytoSorb and ADVOS in patients with ALD led to a significant and comparable decrease in total bilirubin. The easy use of CS might be an advantage compared to other procedures.

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