scholarly journals A Focus on Four Popular “Functional Foods” as Part of a Strategy to Combat Metabolic Disease Through the Increased Consumption of Fruits and Vegetables

2018 ◽  
Vol 6 (2) ◽  
pp. 294-306 ◽  
Author(s):  
Natisha Dukhi ◽  
Myra Taylor

Fruit and vegetable consumption is on the rise as an increasing number of people recognize their health promoting effects, which are mediated through phytochemicals with disease combatting properties. The aim of this paper is to identify the potential benefits of fruits and vegetables in chronic diseases such as diabetes mellitus and hypertension. An electronic search of databases such as Pubmed Central, Science Direct and Web of Science from the last 5 years was conducted. Four commonly consumed edible fruit and vegetables, namely, Hypoxis hemmerocallidea (African potato), Moringa oleifera (Moringa), Persea americana (Avocado) and Psidium guajava (Guava) and their potential role in the prevention and management of metabolic syndrome and other disorders, are presented. In this narrative review plant uses extend beyond traditional medicine and include usage in food preparation, beverages, as part of fragrances, culinary flavouring, as well as cosmetic use, but more importantly have potential in contributing to the amelioration of the deleterious effects of diseases/health conditions. In addressing disease states, including metabolic syndrome and other disorders, the interest in medicinal plants continues to grow with the possibility of novel compounds and/or new drug discovery. Alternative and affordable methods of large scale harvesting of medicinal plants, as well as identification and specificity of bioactive compounds as future therapeutics are essential for sustainability.

2011 ◽  
Vol 107 (6) ◽  
pp. 928-933 ◽  
Author(s):  
Lin-Hong Yuan ◽  
Li-Ping Meng ◽  
Wei-Wei Ma ◽  
Sheng Li ◽  
Jin-Fang Feng ◽  
...  

The correlation of glutathione S-transferase (GST) M1/T1 genetic polymorphisms with oxidative stress-related chronic diseases was proved recently. The aim of the present study was to investigate the association of GSTM1/T1 genetic polymorphisms with antioxidant biomarkers and consumption of fruits and vegetables (F&V) in healthy subjects. In this study, for conducting a 3 d dietary survey, 190 healthy adults were recruited. After DNA extraction, a multiple PCR method was used for GSTM1/T1 genotyping. A spectrophotometer method was applied for the determination of plasma total antioxidant capacity (T-AOC), vitamin C level and erythrocyte GST enzyme activity. A general linear model was used to compare the mean values of antioxidant parameters for different GSTM1/T1 genotypes and consumption of F&V. Polymorphisms of GSTM1/T1 had no effects on plasma T-AOC and vitamin C levels. Deletion of the GSTM1 gene decreased the erythrocyte GST activity. There was correlation between plasma T-AOC and consumption of F&V in the GSTM1− or GSTT1+ subjects. A similar pattern was evident for erythrocyte GST activity in the GSTM1− subjects. No association was found among consumption of F&V and GSTM1/T1 genotypes and plasma vitamin C level. Different consumption of F&V had no impact on plasma T-AOC and vitamin C levels in the GSTM1−/GSTT1+ or GSTM1−/GSTT1− subjects. The erythrocyte GST activity was more sensitive to consumption of F&V in the individuals with the GSTM1−/GSTT1+ genotype. Association was found among GSTM1/T1 genotypes, antioxidant parameters and consumption of F&V. Large-scale and multiple ethnic studies are needed to further evaluate the relationship.


2013 ◽  
Vol 1 (03) ◽  
pp. 120-131 ◽  
Author(s):  
Savinder Kaur Mann ◽  
Namita Khanna

Over the past several years, natural antioxidants have attracted considerable interest as potential treatment for a wide variety of disease states, including cancer and other causes e.g. chronic inflammatory diseases and aging. Therefore, plant derived antioxidants are now receiving a special attention as they possess good antioxidant properties and hence a worldwide trend towards the use of natural phytochemicals present in fruits and vegetables have been reported. Numerous epidemiological studies indicate that consumption of cruciferous vegetables is associated with prevention of cardiovascular diseases and reduced incidence of cancers of the gastrointestinal tract and other sites. The substances that seem to be responsible for these properties are phenolic compounds (phenolic acids, flavonoids, polyphenols etc.) and sulphur-containing organic compound glucosinolates and their derived products. The present review focuses on the health promoting effects of phytochemicals and their beneficial bioactivities in Brassicaceae.


Nutrients ◽  
2019 ◽  
Vol 11 (10) ◽  
pp. 2381 ◽  
Author(s):  
Lapuente ◽  
Estruch ◽  
Shahbaz ◽  
Casas

Noncommunicable diseases (NCDs) are considered to be the leading cause of death worldwide. Inadequate fruit and vegetable intake have been recognized as a risk factor for almost all NCDs (type 2 diabetes mellitus, cancer, and cardiovascular and neurodegenerative diseases). The main aim of this review is to examine the possible protective effect that fruit and vegetable consumption or their bioactive compounds may have on the development of NCDs such as atherosclerosis. The accumulated evidence on the protective effects of adequate consumption of fruits and vegetables in some cases, or the lack of evidence in others, are summarized in the present review. The main conclusion of this review is that well-designed, large-scale, long-term studies are needed to truly understand the role fruit and vegetable consumption or their bioactive compounds have in atherosclerosis.


2017 ◽  
Vol 21 (4) ◽  
pp. 756-765 ◽  
Author(s):  
Yue Tian ◽  
Lijun Su ◽  
Jiantao Wang ◽  
Xiaolin Duan ◽  
Xiubo Jiang

AbstractObjectiveSeveral epidemiological studies have been performed to evaluate the association of fruit and vegetable consumption with risk of the metabolic syndrome (MetS), but the results remain controversial. Thus, we conducted a systematic meta-analysis to assess the associations of fruit or/and vegetable consumption with risk of MetS, separately.DesignWe searched PubMed, EMBASE and Web of Science databases up to July 2017 for relevant available articles. Pooled OR with 95 % CI were calculated with the fixed- or random-effects model.ResultsA total of nine studies for fruit consumption, nine studies for vegetable consumption and seven studies for fruit and vegetable consumption were identified as eligible for the present meta-analysis. The pooled OR (95 % CI) of MetS for the highest v. lowest category were 0·87 (0·82, 0·92; I2=46·7 %) for fruit consumption, 0·85 (0·80, 0·91; I2=0·0 %) for vegetable consumption and 0·76 (0·62, 0·93; I2=83·5 %) for fruit and vegetable consumption. In subgroup analyses stratified by continent where the study was conducted, the inverse association of fruit consumption (0·86 (0·77, 0·96)) and vegetable consumption (0·86 (0·80, 0·92)) with risk of MetS remained significant in Asia. There was no evidence of small-study effect.ConclusionsOur meta-analysis indicates that fruit or/and vegetable consumption may be inversely associated with risk of MetS. It suggests that people should consume more fruits and vegetables to decrease the risk of MetS.


2019 ◽  
Vol 20 (5) ◽  
pp. 433-444 ◽  
Author(s):  
Jhonatas Emílio Ribeiro da Cruz ◽  
Joyce Ferreira da Costa Guerra ◽  
Marcos de Souza Gomes ◽  
Guilherme Ramos Oliveira e Freitas ◽  
Enyara Rezende Morais

Background: Currently, the treatment of infectious diseases has not always been successful due to the emergence of microbial resistance worldwide. Objective: This study aimed to evaluate the antioxidant activity, content of total phenolic compounds and flavonoids, antifungal potential and antibacterial action of six medicinal plants found in the Cerrado, leaf extracts of Boldo (Peumus boldus), Goiaba (Psidium guajava), Assa-Peixe (Vernonia polysphaera), Abacate (Persea americana), Eucalipto (Eucalyptus citriodora) and raw sap of Bálsamo (Jatropha multifida). Methods: The antioxidant activity was also determined through the DPPH, ABTS and phosphomolybdenum assays. In addition, the total phenolic content and flavonoid dosage were analyzed using the Folin- Ciocalteu method and the aluminum chloride test, respectively. Results: All extracts, except from Assa-Peixe, showed promising values against Staphylococcus aureus, with halos varying from 13-20 mm. Analysis of the minimum inhibitory concentration (MIC) values of the six medicinal plants revealed inhibitory activity of S. aureus, with concentrations varying from 3.12-12.5 mg/mL, which is a significant result considering that S. aureus is one of the main causes of hospital infections. Conclusion: In the analysis of the phytochemical profile, Goiaba contained the best yield of phenolic compounds and total flavonoids, as well as higher antioxidant activity by DPPH and phosphomolybdenum, demonstrating that this species contains antioxidant components that can sequester free radicals under in vitro conditions. Therefore, the crude extracts investigated are promising and their antibacterial and antioxidant actions should be thoroughly studied.


Author(s):  
Rose D. Arquion

Ethnobotany is the study of plants used by specific cultures for various purposes. This study aimed to document indigenous medicinal plants which can treat diarrhea. This qualitative study used semi –structured interview and employed purposive sampling of 50 local inhabitants aging 40 to 85 years old presently using medicinal plants in eight communities of Talacogon, Agusan del Sur, Philippines. Results revealed that 25 medicinal plants can treat diarrhea. The leaves and stem of these plants were utilized and prepared by decoction, infusion, concoction and extraction. Out of the 25 identified medicinal plants, Psidium guajava (guava), Persea americana (avocado), and Blumea balsamifera (Blumea camphor) were commonly used which easily grow and can be domesticated in home gardens. The medicinal plants had helped much the local people as a cheap source of alternative medicine. This suggests that this traditional knowledge from these people be transmitted through symposia, seminars and trainings for its management and conservation for sustainability.


Nutrients ◽  
2022 ◽  
Vol 14 (2) ◽  
pp. 263
Author(s):  
Konstantinos-Georgios Papaioannou ◽  
Fawzi Kadi ◽  
Andreas Nilsson

Although consumption of fruits and vegetables (FV) is suggested to reduce metabolic risk, there is a paucity of studies taking advantage of objectively assessed physical activity (PA) behaviors when exploring links between FV intake and metabolic syndrome (MetS) in older adults. The aim of the present study was to determine the relationship between FV intake and MetS prevalence in a population of older community-dwelling adults, while considering time spent being sedentary and health-enhancing PA. Prevalence of MetS was determined in a population of 93 men and 152 women (age: 65–70 years). FV intake was determined by self-report and PA behaviors (time spent in moderate-to-vigorous PA (MVPA) and in sedentary) were assessed by accelerometry. Likelihood of having MetS by FV intake was determined using logistic regression with stepwise backward elimination including age, sex, educational level, total energy intake, adherence to MVPA guideline and total sedentary time as covariates. A main finding was that lower FV intakes were significantly related to higher prevalence of MetS (odds ratio [OR]: 1.23; 95% confidence interval [CI]: 1.03–1.47) after considering potential influences by covariates. Additionally, we found that lower intake of vegetables but not fruits was significantly related to higher prevalence of MetS (OR: 1.47; 95%CI: 1.04–2.07). In conclusion, lower intakes of FV in general, and of vegetables in particular, significantly increased likelihood of MetS, regardless of time spent sedentary and adherence to the MVPA guideline. From a public health perspective, our findings emphasize adequate intakes of FV as an independent contributor to metabolic health status in older adults.


Foods ◽  
2020 ◽  
Vol 9 (3) ◽  
pp. 369 ◽  
Author(s):  
Mercedes del Río-Celestino ◽  
Rafael Font

We edited this Special Issue with the objective of bringing forth new data on the phytochemicals from vegetables and fruits, which are recommended for their health-promoting properties. Epidemiological, toxicological and nutritional studies suggested an association between fruit and vegetable consumption and lower incidence of chronic diseases, such as coronary heart problems, cancer, diabetes, and Alzheimer’s disease. In this Special Issue, the protective roles (antioxidant and others bioactivities), new sustainable approaches to determine the quality, and the processing techniques that can modify the initial nutritional and antioxidant content of fruits, vegetables and additives have been addressed.


Planta Medica ◽  
2008 ◽  
Vol 74 (09) ◽  
Author(s):  
A Sapcanin ◽  
A Imamovic ◽  
E Kovac-Besovic ◽  
K Durić ◽  
I Tahirovic ◽  
...  

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