scholarly journals Health Promoting Effects of Phytochemicals from Brassicaceae: A Review

2013 ◽  
Vol 1 (03) ◽  
pp. 120-131 ◽  
Author(s):  
Savinder Kaur Mann ◽  
Namita Khanna

Over the past several years, natural antioxidants have attracted considerable interest as potential treatment for a wide variety of disease states, including cancer and other causes e.g. chronic inflammatory diseases and aging. Therefore, plant derived antioxidants are now receiving a special attention as they possess good antioxidant properties and hence a worldwide trend towards the use of natural phytochemicals present in fruits and vegetables have been reported. Numerous epidemiological studies indicate that consumption of cruciferous vegetables is associated with prevention of cardiovascular diseases and reduced incidence of cancers of the gastrointestinal tract and other sites. The substances that seem to be responsible for these properties are phenolic compounds (phenolic acids, flavonoids, polyphenols etc.) and sulphur-containing organic compound glucosinolates and their derived products. The present review focuses on the health promoting effects of phytochemicals and their beneficial bioactivities in Brassicaceae.

2004 ◽  
Vol 53 (4) ◽  
pp. 76-81
Author(s):  
E. F. Condrina ◽  
G. N. Ponomarenko

This article provides an overview of scientific publications by domestic and foreign authors over the past 10 years, devoted to the problem of using low-intensity laser therapy in the treatment of chronic inflammatory diseases of the uterine appendages; the analysis of indications and contraindications, advantages and disadvantages of using laser radiation with different characteristics in the treatment of chronic salpingo-oophoritis was carried out; the most significant aspects of the influence of laser therapy on the main pathogenetic mechanisms of the development of the inflammatory process of the uterine appendages are highlighted.


2021 ◽  
Vol 43 ◽  
pp. e57080
Author(s):  
Nabila Benhamada ◽  
Tayeb Idoui

Fermented foods have made important contributions to human diets for thousands of years and continue to do so. Their health-promoting benefits are attracting increasingly attention. The present study was conducted to evaluate the impact of natural fermentation on antioxidant properties of traditionally fermented wheat (Triticum durum) compared to unfermented samples. Initially, the samples were submitted to traditional spontaneous fermentation. Subsequently, an aqueous extract was obtained and used to determine polyphenolic and flavonoid contents. Moreover, the antioxidant potential was also measured through the determination of the scavenging ability against 2,2-diphenyl-1-picrylhydrazyl (DPPH) radicals, reducing power and hydrogen peroxide scavenging activity. The results showed that the total phenolic and total flavonoid contents were significantly increased in fermented wheat. Moreover, the antioxidant activity was more effective in fermented than in unfermented wheat. Thus, natural fermentation can enhance natural antioxidants in wheat and transform it into a healthy food or ingredient with multi-functional properties which can be used in the food industry.


2019 ◽  
Vol 24 (40) ◽  
pp. 4800-4806 ◽  
Author(s):  
Mario F. Neves ◽  
Michelle R. Cunha ◽  
Tainah de Paula

Background: In recent years, it has become more evident that oxidative stress is involved in the development of cardiovascular disease. Indeed, reactive oxygen species seems to be the common mechanism for endothelial dysfunction, vascular inflammation and arterial stiffness, resulting in a blood pressure increase and early vascular aging. Methods: This review presents the potential role of antioxidant nutrients and exercise for cardiovascular protection. Results: Flavonoids, vitamins and minerals present in some fruits and foliage are considered natural antioxidants. In fact, fruits and vegetables contain large amounts of antioxidants. Several clinical trials have extensively studied vitamin E, beta-carotene, vitamin C, polyphenols, plus selenium and zinc. In addition, many authors have been carried out clinical trials to evaluate the mechanisms of oxidative stress attenuation after exercise. Exercise responses may vary according to the Frequency, Intensity, Time and Type (FITT) principle, making it difficult to obtain a consensus concerning the exercise properties and redox status. High-intensity interval training (HIIT) has been reported as an efficient option for metabolic adaptations in a short time. Aerobic exercises must be performed at least three times a week, for two months or more, using moderate to vigorous intensity to promote a positive effect on oxidative stress and vascular function. Conclusion: The recognition of appropriate nutrients and exercise with antioxidant properties may be an important supportive approach to impair early vascular aging and to prevent cardiovascular disease.


2019 ◽  
Vol 20 (3) ◽  
Author(s):  
Marlena Dudek-Makuch ◽  
Kinga Knoska ◽  
Justyna Chanaj-Kaczmarek

In recent years, natural antioxidants are often investigate because of synthetic antioxidants have an adverse effect on human health. Scientific research in the food industry focused on the search for natural antioxidants that would be similarly effective to synthetic antioxidants. For this purpose, commonly known and used natural compounds (e.g. carotenoids), spices and herbs particularly rich in chemical compounds with strong antioxidant properties (e.g. rosemary, thyme, sage, oregano, garlic, cloves) as well as green tea extracts, fruit extracts (e.g. plums, apricots, cranberries) are used. The addition of natural polyphenols not only prolongs the durability of food products, but also protects the body against oxidative damage. Epidemiological studies show a correlation between the consumption of polyphenol-rich products and a reduction in the risk of developing civilization diseases, including heart diseases.


Author(s):  
Noëmie Daniel ◽  
Emelyne Lécuyer ◽  
Benoit Chassaing

AbstractDuring the last 20 years, a new field of research delineating the importance of the microbiota in health and diseases has emerged. Inappropriate host-microbiota interactions have been shown to trigger a wide range of chronic inflammatory diseases, and defining the exact mechanisms behind perturbations of such relationship, as well as ways by which these disturbances can lead to disease states, both remain to be fully elucidated. The mucosa-associated microbiota constitutes a recently studied microbial population closely linked with the promotion of chronic intestinal inflammation and associated disease states. This review will highlight seminal works that have brought into light the importance of the mucosa-associated microbiota in health and diseases, emphasizing the challenges and promises of expending the mucosal microbiology field of research.


2019 ◽  
Vol 20 (6) ◽  
pp. 1475 ◽  
Author(s):  
Adriana Rendon ◽  
Knut Schäkel

Research on psoriasis pathogenesis has largely increased knowledge on skin biology in general. In the past 15 years, breakthroughs in the understanding of the pathogenesis of psoriasis have been translated into targeted and highly effective therapies providing fundamental insights into the pathogenesis of chronic inflammatory diseases with a dominant IL-23/Th17 axis. This review discusses the mechanisms involved in the initiation and development of the disease, as well as the therapeutic options that have arisen from the dissection of the inflammatory psoriatic pathways. Our discussion begins by addressing the inflammatory pathways and key cell types initiating and perpetuating psoriatic inflammation. Next, we describe the role of genetics, associated epigenetic mechanisms, and the interaction of the skin flora in the pathophysiology of psoriasis. Finally, we include a comprehensive review of well-established widely available therapies and novel targeted drugs.


2019 ◽  
Author(s):  
Mateusz Zakrzewski ◽  
Anna Ostrowska ◽  
Zakrzewska Magdalena ◽  
Maciorkowska Elżbieta

Abstract Background: Oxidative stress is a key causative factor in chronic inflammation and plays a key role in the pathogenesis of many chronic inflammatory diseases, including periodontitis. A properly balanced diet abundant in vegetables and fruits can be a rich source of biologically active substances that inhibit reactions with oxygen and ozone. The aim of the study is to assess the influence of natural antioxidants contained in vegetables and fruits on the occurrence and progression of periodontal diseases. Methods: The study covered a group of 368 students of the third grade (at the age of 18) of general secondary schools from the urban environment. The surveyed youth completed a survey regarding their dietary and hygienic habits. Subsequently, they participated in an oral cavity study in which the values of the plaque PL.I and gum GI index were assessed. Results: The beneficial effect on periodontal tissues resulted from eating of fruits and vegetables and frequent consumption of apples and carrots (median GI = 0). Eating of potato chips and crisps and the use of quick-service bars intensified gingivitis (median GI = 0.1). Conclusions: A diet intensifying oxidative stress influenced the deterioration the clinical status during the developmental age.


2017 ◽  
Vol 17 (2) ◽  
pp. 121 ◽  
Author(s):  
Dejan Prvulović ◽  
Đorđe Malenčić ◽  
Jegor Miladinović

Plants are a good source of natural antioxidants and could provide protection against harmful free radicals. Phenolic compounds were found to be an important part of human diet and are considered as active principles in many medicinal and agricultural plants. Detailed information about health-promoting components of different soybean cultivars could lead to a better understanding and an increased consumption of this crop, including its use in functional foods. The objective of this study was to determine total phenolics, total tannins, total flavonoids and antioxidant capacity with different assays of five Serbian soybean cultivars (Merkur, Sava, Valjevka, Venera and Victoria) extracted with three different solvents (70% acetone, 70% ethanol and 70% methanol). Total phenolics varied among cultivars and among applied solvents. Antioxidant properties highly depended on a solvent used for extraction. Such results highlight an existing variability in soybean seeds and emphasise the need to evaluate diversity and to support conventional breeding programs to improve soybean nutritional value.


2018 ◽  
Vol 6 (2) ◽  
pp. 294-306 ◽  
Author(s):  
Natisha Dukhi ◽  
Myra Taylor

Fruit and vegetable consumption is on the rise as an increasing number of people recognize their health promoting effects, which are mediated through phytochemicals with disease combatting properties. The aim of this paper is to identify the potential benefits of fruits and vegetables in chronic diseases such as diabetes mellitus and hypertension. An electronic search of databases such as Pubmed Central, Science Direct and Web of Science from the last 5 years was conducted. Four commonly consumed edible fruit and vegetables, namely, Hypoxis hemmerocallidea (African potato), Moringa oleifera (Moringa), Persea americana (Avocado) and Psidium guajava (Guava) and their potential role in the prevention and management of metabolic syndrome and other disorders, are presented. In this narrative review plant uses extend beyond traditional medicine and include usage in food preparation, beverages, as part of fragrances, culinary flavouring, as well as cosmetic use, but more importantly have potential in contributing to the amelioration of the deleterious effects of diseases/health conditions. In addressing disease states, including metabolic syndrome and other disorders, the interest in medicinal plants continues to grow with the possibility of novel compounds and/or new drug discovery. Alternative and affordable methods of large scale harvesting of medicinal plants, as well as identification and specificity of bioactive compounds as future therapeutics are essential for sustainability.


2020 ◽  
Vol 10 (4) ◽  
pp. 446-458 ◽  
Author(s):  
Toyin Dorcas Alabi ◽  
Nicole Lisa Brooks ◽  
Oluwafemi Omoniyi Oguntibeju

Background: Anchomanes difformis (ENGL: Blume) is a specie of flowering plants in the family Araceae. Anchomanes difformis is commonly reported for ameliorating hyperglycemia, inflammation, ulcer, malaria, and inhibiting microbial growth. Objective: This study evaluated total yields of phytochemicals present, measured antioxidant capacities and identified bioactive compounds in the leaves and rhizome extracts of A. difformis using solvents of different polarity (ethyl acetate, ethanol and water). Methods: Total polyphenolic, flavonoid content and alkaloids were measured, ORAC, TEAC and FRAP were performed as antioxidant capacity indices, and identification of bioactive compounds was done using UPLC-MS and HPLC. Results: All extracts contained polyphenols, flavonols, flavanols, and alkaloids in varying concentrations. All extracts exhibited antioxidant properties. However, aqueous leaves extract had the highest antioxidant properties and polyphenols with significance (p<0.05). Thirty-four compounds were identified altogether in the leaves and rhizome. Conclusion: A. difformis leaves and rhizome are potential sources of natural antioxidants and can serve as potential therapeutic agents against diseases linked with oxidative stress. Presence of health-promoting compounds indicates possible ameliorative potentials of A. difformis.


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