Makeraia gen. nov. (Hymenoptera, Bethylidae), a long-antennated Pristocerinae from Madagascar

2021 ◽  
Vol 28 (2) ◽  
Author(s):  
DANIELE MUGRABI ◽  
CELSO AZEVEDO
Keyword(s):  

Here we describe the flat wasp genus Makeraia gen. nov., and its three species M. migueli sp. nov., M. clariceae sp. nov. and M. lacinia sp. nov. from Madagascar. The males of this genus are easily recognized among the other genera of Pristocerinae by having the antennae very long, about as long as the whole body, a condition unique in Bethylidae. Our findings emphasize the endemicity of the flat wasp fauna of Madagascar and its high potential of biodiversity.

1987 ◽  
Vol 26 (05) ◽  
pp. 202-205 ◽  
Author(s):  
J. Fass ◽  
S. Truong ◽  
U. Büll ◽  
V. Schumpelick ◽  
R. Bares

Radioimmunoscintigraphy (RIS) with 111ln- and 131 I-labelled monoclonal anti bodies (MAbs) against CEA and/or CA 19-9 was performed in 83 patients with various gastrointestinal carcinomas. A total of 276 body regions could be examined. The results of planar scintigraphy and SPECT were compared intraindividually. Using 111 In-labelled MAbs the sensitivity of RIS was significantly improved by SPECT (88.9 vs. 52.4% with planar scintigraphy, p <0.01). For131 l-labelled MAbs the effect was smaller (83.9 vs. 65.6% with planar scintigraphy, n.s.). This finding can be explained by different kinetics and biodistribution of the used MAb preparations.111 In-labelled MAbs with long whole-body retention and rapid blood clearance reveal ideal qualities for SPECT; on the other hand, the short whole-body retention of131 l-labelled MAbs leads to small count rates and therefore long counting times that make delayed SPECT unsuitable in clinical practice


1952 ◽  
Vol 98 (411) ◽  
pp. 330-333 ◽  
Author(s):  
Joan FitzHerbert

In a paper published in the Journal of Mental Science for July, 1950, I suggested that head-banging originated in the infant's desire to reproduce the thrust of the mother's apex-beat against his head while he was being nursed on her left arm, either as a means of self-comfort or in retaliation for what he had felt to be an attack or as both combined. In the present paper I propose to analyse this infantile experience further, and to trace to some of its component elements certain other peculiarities of childish behaviour.I shall begin by considering the case of a bottle-fed baby, that is to say, one who at every feed is held in his mother's left arm with his right temple against her left breast (and I shall suppose that the mother is not herself a case of dextrocardia.) In addition to the teat in his mouth and the milk being swallowed, such an infant feels the thrust of the mother's apex as a series of taps against his head which tend to impart to the latter a rolling side-to-side movement, he hears her heart-beat as a rhythmic lub-dup, he feels the rise and fall of her chest in respiration as a slower to and fro rocking of his whole body, and he hears the sighing rustle of her breathing beneath his ear. The sound and thrust of the heart-beat are of course louder and stronger at the limit of the mother's expirations, and indeed the tap of the apex may be felt only then. In other words, the suckling hears two separate series of interwoven unsynchronized rhythmic sounds continuing throughout the whole of his feeding times. In addition to all this, he feels the warmth of the maternal body, the steady clasp of the mother's arm, he smells the milk and the woman's body odour (sweaty, or scented by her soap and talcum powder), and lastly, he feels (and may smell) her breath as an intermittent warm breeze on his face and in his hair. The mother seldom speaks while she is feeding her baby, and the room is often quiet, mother and child being alone together. A breast-fed baby also feels smooth warm skin under his fingers, but he has the mother's heart against his head, during only half his feeding times.The other occasions on which a woman commonly holds a child firmly against her breast are, of course, when she is trying to comfort a crying baby, or to restrain a struggling toddler from escaping to some forbidden activity. Here the child is angry and the mother herself often either anxious or angry or both, so that her heartbeat is greatly increased in force, and the furious infant feels it as a series of aggressive blows on his head, each of which is accompanied by a bumping noise.


1906 ◽  
Vol 25 (2) ◽  
pp. 903-907
Author(s):  
George A. Carse

The apparatus used to show that aluminium was opaque to the ions from a flame consisted (see fig. 1) of a tube A, which wasfunnel-shaped at one end, the other end of which led to an enclosure B, one side of which (a b) was made of aluminium foil connected to earth, and on the other side there was an insulated metallic plate (c d), which could either be connected to earth or to a high potential battery. On the other side of the aluminium foil there was an electroscope in a closed case C. The electroscope was of the type used by C. T. R. Wilson in his experiments on the natural ionisation of air in closed vessels.


2021 ◽  
Vol 9 (2) ◽  
pp. e002039
Author(s):  
Noor Suleiman ◽  
Meis Alkasem ◽  
Shaimaa Hassoun ◽  
Ibrahem Abdalhakam ◽  
Ilham Bettahi ◽  
...  

IntroductionDecreased insulin sensitivity occurs early in type 2 diabetes (T2D). T2D is highly prevalent in the Middle East and North Africa regions. This study assessed the variations in insulin sensitivity in normal apparently healthy subjects and the levels of adiponectin, adipsin and inflammatory markers.Research design and methodsA total of 60 participants (aged 18–45, body mass index <28) with a normal oral glucose tolerance test (OGTT) completed hyperinsulinemic-euglycemic clamp (40 mU/m2/min) and body composition test by dual-energy X-ray absorptiometry scan. Blood samples were assayed for glucose, insulin, C peptide, inflammatory markers, oxidative stress markers, adiponectin and adipsin.ResultsThe subjects showed wide variations in the whole-body glucose disposal rate (M value) from 2 to 20 mg/kg/min and were divided into three groups: most responsive (M>12 mg/kg/min, n=17), least responsive (M≤6 mg/kg/min, n=14) and intermediate responsive (M=6.1–12 mg/kg/min, n=29). Insulin and C peptide responses to OGTT were highest among the least insulin sensitive group. Triglycerides, cholesterol, alanine transaminase (ALT) and albumin levels were higher in the least responsive group compared with the other groups. Among the inflammatory markers, C reactive protein (CRP) was highest in the least sensitivity group compared with the other groups; however, there were no differences in the level of soluble receptor for advanced glycation end products and Tumor Necrosis Factor Receptor Superfamily 1B (TNFRS1B). Plasma levels of insulin sensitivity markers, adiponectin and adipsin, and oxidative stress markers, oxidized low-density lipoprotein, total antioxidant capacity and glutathione peroxidase 1, were similar between the groups.ConclusionsA wide range in insulin sensitivity and significant differences in triglycerides, cholesterol, ALT and CRP concentrations were observed despite the fact that the study subjects were homogenous in terms of age, gender and ethnic background, and all had normal screening comprehensive chemistry and normal glucose response to OGTT. The striking differences in insulin sensitivity reflect differences in genetic predisposition and/or environmental exposure. The low insulin sensitivity status associated with increased insulin level may represent an early stage of metabolic abnormality.


2016 ◽  
Vol 231 (3) ◽  
pp. R77-R99 ◽  
Author(s):  
Liping Luo ◽  
Meilian Liu

Adipose tissue plays a central role in regulating whole-body energy and glucose homeostasis through its subtle functions at both organ and systemic levels. On one hand, adipose tissue stores energy in the form of lipid and controls the lipid mobilization and distribution in the body. On the other hand, adipose tissue acts as an endocrine organ and produces numerous bioactive factors such as adipokines that communicate with other organs and modulate a range of metabolic pathways. Moreover, brown and beige adipose tissue burn lipid by dissipating energy in the form of heat to maintain euthermia, and have been considered as a new way to counteract obesity. Therefore, adipose tissue dysfunction plays a prominent role in the development of obesity and its related disorders such as insulin resistance, cardiovascular disease, diabetes, depression and cancer. In this review, we will summarize the recent findings of adipose tissue in the control of metabolism, focusing on its endocrine and thermogenic function.


1987 ◽  
Vol 1 (2) ◽  
pp. 236-244 ◽  
Author(s):  
T. Kawamoto ◽  
M. Shimizu

The distribution of calcium and phosphate in the cells of the enamel organ of the rat lower incisors was investigated by autoradiography and energy-dispersive x-ray spectrometry (EDS). Radioactive calcium or phosphate was injected i.p. into seven-day-old rats of the Wistar strain. The animals were frozen 0.5, 1, and 10 min after injection, and embedded in 5% carboxymethyl cellulose. Sagittal sections of 10 μm thickness were made in which the lower incisor was included as a part of the whole-body section. For autoradiography, the sections were freeze-dried and placed in contact with dry thin films prepared from autoradiographic emulsion. For EDS, sections were mounted on carbon stubs, freeze-dried, coated with carbon, and examined by EDS in a SEM. 45Ca and 32P autoradiograms showed that the radioactivity was located over the papillary layer cells adjacent to the secretory stage ameloblasts and was much higher here than in the ameloblastic layer. On the other hand, there was no significant difference between the amount of radioactivity of these two cell layers in the maturation stage, although higher radioactivity was detectable in the maturation stage enamel than in the secretory stage enamel. Pronounced Ka x-ray peaks were obtained for P, S, Cl, and K originating from the cells of the papillary and ameloblastic layers in the secretory stage, but only very low peaks were obtained for Ca. On the other hand, in addition to these elements, remarkably high Ca and Fe peaks could be detected in the ameloblastic layer of the maturation stage.


2020 ◽  
Vol 21 (4) ◽  
pp. 1196 ◽  
Author(s):  
Serazhutdin Abdullaev ◽  
Nina Gubina ◽  
Tatiana Bulanova ◽  
Azhub Gaziev

Studies of molecular changes occurred in various brain regions after whole-body irradiation showed a significant increase in terms of the importance in gaining insight into how to slow down or prevent the development of long-term side effects such as carcinogenesis, cognitive impairment and other pathologies. We have analyzed nDNA damage and repair, changes in mitochondrial DNA (mtDNA) copy number and in the level of mtDNA heteroplasmy, and also examined changes in the expression of genes involved in the regulation of mitochondrial biogenesis and dynamics in three areas of the rat brain (hippocampus, cortex and cerebellum) after whole-body X-ray irradiation. Long amplicon quantitative polymerase chain reaction (LA-QPCR) was used to detect nDNA and mtDNA damage. The level of mtDNA heteroplasmy was estimated using Surveyor nuclease technology. The mtDNA copy numbers and expression levels of a number of genes were determined by real-time PCR. The results showed that the repair of nDNA damage in the rat brain regions occurs slowly within 24 h; in the hippocampus, this process runs much slower. The number of mtDNA copies in three regions of the rat brain increases with a simultaneous increase in mtDNA heteroplasmy. However, in the hippocampus, the copy number of mutant mtDNAs increases significantly by the time point of 24 h after radiation exposure. Our analysis shows that in the brain regions of irradiated rats, there is a decrease in the expression of genes (ND2, CytB, ATP5O) involved in ATP synthesis, although by the same time point after irradiation, an increase in transcripts of genes regulating mitochondrial biogenesis is observed. On the other hand, analysis of genes that control the dynamics of mitochondria (Mfn1, Fis1) revealed that sharp decrease in gene expression level occurred, only in the hippocampus. Consequently, the structural and functional characteristics of the hippocampus of rats exposed to whole-body radiation can be different, most significantly from those of the other brain regions.


1983 ◽  
Vol 54 (6) ◽  
pp. 1518-1524 ◽  
Author(s):  
S. M. Cain ◽  
R. P. Adams

Cardiac output and mean arterial pressure were decreased in two groups of 16 anesthetized paralyzed dogs ventilated by pump. Pericardial tamponade was used in one group, and hemorrhagic hypotension was used in the other. After a 30-min control period and 30 min of circulatory shock by either method, 0.3N HCl was infused into half the dogs in each group and 1.0N NaHCO3 into the other half so that pH was separated by 0.3–0.4 units. The slope of the line relating O2 uptake to total O2 transport (blood flow X arterial O2 concentration) was used to evaluate how well the tissues extracted O2 relative to O2 supply. During the initial shock period before infusion, the slope of the line relating O2 uptake of left hindlimb skeletal muscle to total O2 transport in the limb was almost twice as great as that for the whole body. Acid infusion increased the slope of the whole-body line but did not alter that for the hindlimb. Base infusion, on the other hand, decreased the slope of the line for the limb during hemorrhagic shock but had no other effect. We concluded that acid either improved the distribution of a limiting blood supply to nonmuscle organ systems, or increased tissue capillary PO2 and O2 diffusion by decreasing hemoglobin O2 affinity (HOA), or both. The effect of an increased HOA with base infusion was noticeable in hindlimb skeletal muscle only when volume depletion by hemorrhage presumably greatly increased the normally short intercapillary diffusion distance in muscle.


1988 ◽  
Vol 24 (1-4) ◽  
pp. 143-147 ◽  
Author(s):  
B. Descamps ◽  
L. Foulquier

Abstract The study is based on data covering the water, sediments, plants and fish sampled over a 20-year period at 15 stations along French rivers. Three geographic zones were investigated: one containing a uranium mining complex (Zone 1), another including five major rivers along which nuclear power plants are sited (Zone II) and a third unaffected by nuclear activities (Zone III). Natural radioactivity basically involves 238U, 226Ra and 210Pb in the uranium series, 232Th from the thorium series, 40K and 7Be. The natural radioactivity in Zone II is not different from Zone III, and is thus unaffected by waste discharges from nuclear power plants. The most abundant radionuclide is 40K, while the other nuclides are often found in trace amounts near the detection threshold of the analysis method used (Ge gamma spectrometry with a 15-hour counting period). The 226Ra and 238U concentrations observed in Zone I are at least an order of magnitude higher than in the other two zones due to authorised waste discharges from the Lodève mining complex, but only a small stream is affected. The measured 226Ra concentrations would result in an annual whole body committed dose equivalent attributable to a 200 g weekly fish consumption from this stream of 4.4 x 10-5 Sv.y-1, or 0.86% of the maximum permissible dose (5 mSv).


2001 ◽  
Vol 86 (2) ◽  
pp. 249-255
Author(s):  
Zhen-Yu Chen ◽  
Kwok Yiu Kwan ◽  
Yu Huang

Dietary cis,trans-18 : 2 isomers impair desaturation and elongation of linoleic acid (Δ9cis,12cis-18 : 2), but little is known of their proportional partitioning between accumulation and oxidation. The present study was therefore designed to assess the accumulation and apparent oxidation of cis,trans-18 : 2 isomers compared with that of trans-18 : 1 isomers and Δ9cis,12cis-18 : 2 in rats. Accumulation is defined as whole-body increase in a fatty acid during a given period (i.e. final body content-initial body content). The apparent oxidation (disappearance) is defined as whole-body utilization of a fatty acid relative to its intake for a given period (intake-excretion-accumulation-longer-chain products)/intake×100). The animals were fed on a diet containing 15 % (w/w) partially hydrogenated rapeseed oil with 1·72 % energy as cis,trans-18 : 2 isomers and varying amounts of Δ9cis,12cis-18 : 2. The apparent oxidation of total cis,trans-18 : 2 isomers (72–76 % dietary intake) was greater than that of Δ9cis,12cis-18 : 2 (38–51 % dietary intake) but it was similar to that of total trans-18 : 1 isomers (78–82 % dietary intake). Among the four isomers, the apparent oxidation of Δ9trans,12trans-18 : 2 was greater than that of the other isomers including Δ9trans,12cis-18 : 2, Δ9cis,12trans-18 : 2 and Δ9cis,13trans-18 : 2. Accumulation of Δ5cis,8cis,11cis,15trans-20 : 4 and Δ5cis,8cis,11cis,14trans-20 : 4 derived from chain-elongation and desaturation of Δ9cis,13trans-18 : 2 and Δ9cis,12trans-18 : 2 was decreased when the dietary Δ9cis,12cis-18 : 2 supply was increased.


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