scholarly journals β-endorphin response to aerobic and anaerobic exercises in Wistar male rats

2020 ◽  
Vol 29 (3) ◽  
pp. 245-9
Author(s):  
Rostika Flora ◽  
Mohammad Zulkarnain ◽  
Sukirno

BACKGROUND Physical exercise is strongly associated with the release of β-endorphin. It is assumed that the type and intensity of physical exercise contributes to the release of β-endorphin. This study aimed to compare levels of β-endorphin in brain tissue in response to aerobic and anaerobic physical exercise. METHODS This study was an experimental laboratory study using 35 male Wistar rats divided into one control group and two physical exercise treatment groups: aerobic and anaerobic. Physical exercise was conducted on an animal treadmill running at aspeed of 20 m/min for 30 min of aerobic exercise and 35 m/min with 1-min intervals every 5 min for 20 min for anaerobic exercises. Each aerobic and anaerobic exercise group was furtherly classified into three subgroups (1×/week, 3×/week, and 7×/week). β-endorphin levels were determined using enzyme-linked immunosorbent assay. The data were analyzed using independent t-test and one-way analysis of variance. RESULTS The highest mean of β-endorphin level was found in the weekly exercise (54.45 [1.41] pg/ml) of aerobic exercise group and daily exercise (70.50 [11.67] pg/ml) of anaerobic exercise group. Mean of β-endorphin level in control group was 33.34 (3.54) pg/ml. A significant increased of β-endorphin mean level (p<0.001) was found in all aerobic and anaerobic exercise groups except the aerobic exercise 7×/week group(37.37 [6.30] pg/ml) compared to control. CONCLUSIONS Both aerobic and anaerobic physical exercise conducted for 6 weeks could increase the level of β-endorphin in brain tissue.

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Muhammed Emre Karaman ◽  
Cengiz Arslan ◽  
Mehmet Ferit Gürsu

Abstract Objectives The number of studies examining the circulating level change of betatrophin and cartonectin in metabolic syndrome applying different loads of exercise is limited. The purpose of the present study was to investigate how different loads of exercises regulate the betatrophin and cartonectin levels in metabolic syndrome induced rats. Methods A total of 24 Wistar-Albino male rats were used in the study. Rats were divided into four groups as follows; G1: control group (fed with standard diet and tap water), G2: metabolic syndrome group (without exercise application), G3: metabolic syndrome + aerobic exercise group (aerobic exercise applied), G4: metabolic syndrome + anaerobic exercise group (anaerobic exercise applied). Betatrophin and Cartonectin levels were determined by ELISA method in serum samples. Results There was a statistically significant difference in betatrophin levels between the groups and this differentiation was caused by G2 (p <0.05). Cartonectin levels were not significantly different between groups (p> 0.05). Conclusions It can be concluded that anaerobic exercises have more positive effects on glucose balance in metabolic syndrome than aerobic exercises, and by regulating betatrophin levels, anaerobic exercises indicate this effect.


2018 ◽  
Vol 27 (2) ◽  
Author(s):  
Mohammad Zulkarnain ◽  
Rostika Flora ◽  
Septi Andrianti

Background:Aerobic and anaerobic physical exercises conducted in both acute and chronic are really essential in keeping the body especially brain healthy. Physical exercise plays an important role in molecular system and is beneficial for the brain by enhancing neurogenesis which is mediated by the increase of BDNF level. This study aimed to evaluate the effect of physical exercise to the BDNF level of hippocampus tissues in Wistar rats.Methods: Thirty male rats were divided into five groups i.e. control group, acute aerobic physical exercise group, acute anaerobic physical exercise group, chronic aerobic physical exercise group, and chronic anaerobic physical exercise group. Physical exercises were conducted on animal treadmill. The level of hippocampus BDNF was determined using ELISA. The data were analyzed using independent t-test.Results: BDNF average levels of chronic aerobic and anaerobic physical exercises were higher than those of acute ones (152.86±1.62 pg/ml and 122.22±1.53 pg/ml vs 59.38±6.10 pg/ml and 54.05±3.35 pg/ml). There were significant differences in the BDNF average levels of hippocampus tissues between aerobic and anaerobic groups, in both acute and chronic exercise.Conclusion: The chronic physical exercises, both aerobic or anaerobic, are increasing higher the level of BDNF in brain tissue.


2019 ◽  
Vol 53 (5) ◽  
Author(s):  
Aqsa Sjuhada Oki ◽  
Nurul Farhana ◽  
Yuliati

Introduction. The healing process of tooth extraction is desired to take place faster to restore the normal tissue. Physical exercise is proven to accelerate wound healing through various physiological mechanisms. Aerobic exercise increases oxygen perfusion which leads to wound healing process. On the other hand, anaerobic exercise stimulates reactive oxygen species and may interfere with the wound healing process. Objective. To observe if there are differences in the effectiveness of wound healing after tooth extraction based on the number of fibroblast and neovascularization in Wistar rats (Rattus norvegicus) that performed interval aerobic or anaerobic exercise. Methods. Rats were divided into 3 groups, a control group and two treatment groups which performed the aerobic physical exercise or the anaerobic physical exercise. Fibroblast and neovascularization were calculated 7 days after the tooth extraction. Data were analyzed using Krusskal-Wallis statistical tests. Results. The aerobic exercise group showed the higher number of fibroblasts and neovascularization compared to anaerobic exercise group, while the control group showed the lowest number of fibroblast and neovascularization. Conclusion. This study demonstrated that aerobic physical exercise accelerates wound healing in the proliferation phase better than anaerobic exercise and no exercise.


2019 ◽  
Vol 50 (5) ◽  
pp. 987-998 ◽  
Author(s):  
Juliane Barroso Leal ◽  
Juçara Barroso Leal ◽  
Joaline Barroso Portela Leal ◽  
Yan de Lima Borges ◽  
Maria Ivone Leal de Moura ◽  
...  

Purpose This paper aims to verify the effect of 12 weeks of grape juice (GJ) consumption associated with aerobic exercise on the variation of the hypertensive elderly pressure. Design/methodology/approach A total of 45 hypertensive elderly of both sexes were distributed into: control group (CG, n = 10), exercise group (EG, n = 10), juice group (JG, n = 12) and juice and exercise group (JEG, n = 13). Blood pressure and heart rate were checked weekly before exercise in JG and JEG, and before and after intervention in all groups, with JG and JEG supplemented with 200 mL of GJ. Three weekly sessions of moderate walking were applied. Findings There was a reduction in EG, JG and JEG for systolic pressure and diastolic only for JG and JEG. The GJ consumption to the practice of aerobic exercise provided reductions in the arterial pressure of hypertensive, in addition to stabilization of the diastolic pressure. Research limitations/implications Although the objective of the study was to compare the effect and value of intervention with controls, the study had no intervention in food consumption, which could have led to more significant results. There was a limitation in the control drink, leading the study not to be blind, which may have impaired the results. However, it is probably not a bias, as the groups were divided by residence area, and therefore, had no direct contact with the other groups. Another limitation was that the sample size was still small, which would lead to more reliable results. Finally, although the existing limitations cannot be disregarded, the results of this research are very promising, especially when the objective is the effect of GJ and aerobic exercise on blood pressure, with the possibility of implementing supplemental GJ and the inclusion or not of exercise to the hypertensive elderly. Originality/value The paper deals with the benefits of GJ consumption associated with aerobic physical exercise on the blood pressure of elderly hypertensive patients. Considering that GJ along with physical exercise was enough to reduce the blood pressure of hypertensive elderly, this may be a new model to be used to reduce and/or control blood pressure, and GJ and the exercise to be part of the daily life of the population.


2020 ◽  
Vol 53 (4) ◽  
pp. 196
Author(s):  
Aqsa Sjuhada Oki ◽  
Moch Febi Alviansyah ◽  
Christian Khoswanto ◽  
Retno Pudji Rahayu ◽  
Muhammad Luthfi

Background: Physical exercise has been proven to accelerate wound healing. Physical training itself consists of aerobic (continuous training) and anaerobic (interval training) exercise. The effectiveness of continuous physical exercise on post-tooth extraction wound healing is the focus of this study. Purpose: This study aims to investigate the differences in post-tooth extraction wound healing in Wistar rats (Rattus norvegicus) after aerobic and anaerobic exercise based on the number of fibroblasts and neovascularisation. Methods: Wistar rats were divided into three groups: the control group (K1); K2 undertook continuous aerobic exercise, swimming at 50% maximum swimming capacity (MSC) with an additional 3% bodyweight load; K3 undertook anaerobic continuous exercise, swimming at 65% MSC with a 6% load. The rats swam three times per week for six weeks. The number of fibroblasts and neovascularisation were examined three days after tooth extraction. Data was analysed using the one-way analysis of variance (ANOVA) and Least Significant Difference (LSD) tests (p<0.05). Results: There was a significant difference in the number of fibroblasts between the K2 and K3 groups. There was no significant difference between K2 and K3 in the amount of neovascularisation. Conclusion: There were differences in the number of fibroblasts but not neovascularisation after tooth extraction in Wistar rats given aerobic and anaerobic continuous training.


2018 ◽  
Vol 1 (5) ◽  
Author(s):  
Feng Hong

Objective Breast cancer is one of the most common malignant tumors in women.The number of women diagnosed with breast cancer each year is also increasing.It is also the leading cause of cancer deaths in women, accounting for 14-23% of cancer deaths.However, with the development of medical technology, the survival rate of breast cancer patients is improving.In general, the treatment of breast cancer mainly includes surgical treatment, adjuvant chemotherapy and radiotherapy,But these treatments can do a lot of damage to breast cancer patients.These injuries can limit some of the physical activity of breast cancer patients, and can be accompanied by significant psychological damage,Therefore, the quality of life of breast survivors is largely destroyed.Physical exercise is one of the important ways to improve the overall health of the human body.It also plays an important role in increasing people's mood and quality of life.So whether physical exercise has a positive impact on improving the quality of life of breast cancer survivors or there is some doubt.Therefore, the main purpose of this study is to explore the impact of physical exercise on the quality of life of breast cancer survivors, and then to prove the impact of supervised exercise and individual exercise on the quality of life of breast cancer survivors. Methods Data bases searched were MEDLINE, EMBASE, CINAHL, PubMed.Keywords were“breast cancer and quality of life” in combination with “exercise”or “physical activity”.At the same time, the references of the included articles were reviewed to obtain more relevant studies.In terms of the criteria for inclusion and exclusion of literature, the paper was initially screened to determine whether the title and abstract of the paper were consistent with the research topic.The criteria for inclusion are ①the subjects were breast cancer survivors,②the type of intervention was physical exercise,③the measured result is quality of life,④the type of experiment is randomized controlled trial.The exclusion criteria of the article are ①the subject's occupation was athlete,②quality of life is not measured on a formal scale,③article type is review or abstract. Results A total of 14 articles are included in our review.Quality of life was measured using scale tools in all included studies, of which two scales were used in all included articles.The two scales used can reflect the real life quality of the subjects, of which FACT-G is a mass life quality scale and FACT-B is a life quality scale designed specifically for breast cancer patients. Both scales are globally recognized by the public.In our review, we found that exercise significantly improved the quality of life of breast cancer survivors, particularly aerobic exercise.In the studies included in our study, except Nanette et al. used aerobic exercise combined with resistance strength training as the intervention method in their study, all the other studies used aerobic exercise as the intervention method for the subjects.Among the 14 included studies, 10 indicated that physical exercise significantly increased the quality of life of breast cancer survivors, and 4 found that compared with the control group, the quality of life of breast cancer survivors did not have significant changes, but there was a trend of improving the quality of life.At the same time, our review found that monitoring breast cancer survivors improved quality of life.In two of the studies we included, subjects were divided into individual exercise groups and supervised exercise groups.In their study, Anne et al. divided the recruited research samples into the supervision intervention group and the routine control group. Among them, the supervision intervention group received physical exercise 5 times a week for 12 weeks, and the quality of life of breast cancer survivors was significantly improved.In the study of Cadmus et al., the subjects recruited were divided into individual exercise group, supervised exercise group and routine control group, and the exercise group performed physical exercise with the same load and frequency. The result was that there was no physical activity in the home individual exercise group or the routine control group that improved the quality of life for breast cancer survivors.However, in the supervised exercise group, breast cancer survivors' scores for FACT-B and SF-36 (a measure reflecting quality of life) were significantly improved. Conclusions Exercise can improve the quality of life for breast cancer survivors, especially aerobic exercise. Supervised exercise intervention for breast cancer survivors can better improve their quality of life and alleviate social and psychological problems than individual exercise.The supervised aerobic exercise can be integrated into the life of breast cancer survivors so as to better promote the recovery of breast cancer survivors.


2020 ◽  
Vol 26 (2) ◽  
pp. 156-169
Author(s):  
Abbas Saremi ◽  
◽  
Mohammad Parastesh ◽  
Leili Mohammadi ◽  
◽  
...  

Aims Resistin is secreted by adipose tissue and could be the link between diabetes and infertility. This study aimed to investigate the alteration of resistin following aerobic exercise training in diabetic rats and its possible interaction with sperm parameters. Methods & Materials In this experimental study, 30 male Wistar rats (age: 56 days, weight: 200-250g) were randomly divided equally into three groups of healthy control, diabetic control, and diabetic aerobic exercises. Diabetes was induced with a unique intraperitoneal injection (65 mg/kg body weight) of streptozotocin. Seven days after the injection and after 12 hours of fasting, the animals with blood glucose levels of ≥250 mg/dL were considered diabetic. Seven days after the induction of diabetes, the animals in the exercise group were subjected to progressive aerobic training (treadmill running for 1 h, 27 m/min, 5 d/wk). After 10 weeks of exercise, the sperm quality and resistin concentrations were measured. The obtained data were compared using Analysis of Variance (ANOVA) (P<0.05). Findings The induction of diabetes significantly decreased sperm count (P=0.001), motility (P=0.001), viability (P=0.001), and morphology (P=0.01). The sperm parameters, such as count (P=0.03) and viability (P=0.002) were significantly higher in the diabetic exercise group, compared to the diabetic sedentary group. No significant changes were found in resistin levels between diabetic exercise and diabetic sedentary groups (P=0.40). Conclusion The collected results indicated that the 10-week aerobic training regimen improved sperm quality, independent of changes in resistin levels, in type 2 diabetes mellitus rat models.


Author(s):  
Budijanto Budijanto

Doing exercises regularly is useful to help improve strength, frmness, and endurance and also to avoid early aging process The best exercises to make body healthy are swimming, quick hiking, jogging, and cycling. The goal of the research was to verify the difference of influence toward aerobic and anaerobic exercises towards the change of cholesterol, cholesterol HDL and LDL as well as ratio of cholesterol HDL and LDL. The research was experimental using post test and control group. The sample was classifed into three groups, each of which consisting 10 mice and then randomly aerobic and anaerobic exercises and control group were done. The aerobic exercise by swimming used 3% burden of body weight for 13 minutes and the anaerobic exercise 9% for 0ne minute by taking rest for 3 minutes intermittently as many as 4 sets, while control group did it without exercise. Based on the data analysis, it was found that aerobic exercises was effective to reduce cholesterol, improve cholesterol of HDL and LDL, and ratio of cholesterol of HDL and LDL. In addition the aerobic exercise was better than anaerobic exercise


2016 ◽  
Vol 26 (4) ◽  
pp. 104 ◽  
Author(s):  
M Magalhaes

Background. Stress is an integral part of daily living, but chronic activation of the stress response without the ability to express the physical response results in overloading of the physiological and psychological systems. Objective. To decrease perceived stress by means of one known and/or one relatively unknown physical activity, namely aerobic exercise and somatic awareness exercise. Methods. This investigation made use of a quantitative, comparative, experimental research design over an 8-week period using pre- and post-tests. Participants were measured for psychological stress using a perceived stress scale. The participants were divided into those who were physically untrained and those who participated in exercise training programmes. Results. There were five groups in total. The physically untrained individuals were divided into four groups: a somatic awareness exercise group (n=9); an aerobic exercise group (n=15); a combination group taking part in both somatic awareness and aerobic exercise (n=8); and a control group (n=15). The 5th group contained individuals who participated in physical exercise prior to entering the programme; they were given somatic awareness exercise (n=9) in addition to their existing physical exercises. An independent samples t-test revealed significant changes for perceived stress in the aerobic, somatic, combination and exercise groups, with a 95% confidence level in comparison with the control group. Conclusion. Various physical modes such as aerobic exercise, somatic awareness training and a combination of the two may be used to decrease one’s perceived stress in moderately to highly stressed individuals who are sedentary or who are physically active


2018 ◽  
Vol 1 (4) ◽  
Author(s):  
Yangwenjie Wang ◽  
Ying Zhang

Objective Apelin, an adipokine and also a myokine, is involved in energy metabolism. F13A is an analog of apelin-13. In this study, we aim to investigate the effect of aerobic exercise on F13A-mediated energy metabolism in mice. Methods 20 C57BL/6J wild mice were randomly divided into 4 groups(n:5), namely saline control group(SC), saline exercise group(SE), F13A control group(FC), and F13A exercise group(FE). Mice were intraperitoneally injected with F13A(0.2 μmol/kg/day) or saline(15 μl/kg/day). Mice in the exercise group underwent 60 min/day treadmill running at a speed of 15 m/min with a slope of 5 º. After 2 weeks, the maximal oxygen uptake was measured and the running speed was adjusted to 20 m/min. The treadmill running continued 4 weeks. The mice were individually housed in a Comprehensive Lab Animal Monitoring System(Columbus Instruments, Columbus, OH, USA) between the 3rd and 4th week of training with free access to food and water. O2 consumption(VO2), CO2 production(VCO2) and respiratory exchange ratio(RER) during a 24-h period were measured after 24h of acclimatization. Glucose oxidation(in g/min/kg0.75=[(4.545×VCO2)−(3.205×VO2)]/1000), and lipid oxidation(in g/min/kg0.75=[1.672×(VO2−VCO2)]/1000) were calculated. Results F13A alone increased glucose oxidation(P<0.01, vs SC group). Exercise plus F13A caused a significant decline in RER(P<0.01 vs FC and P<0.05 vs SE group), glucose oxidation(P<0.001 vs FC and P<0.05 vs SE group), whereas it increased lipid oxidation(P<0.05 in comparison with FC group). Exercise alone has no in fluence on 4 groups. Conclusions These findings suggest that 4 weeks aerobic exercise can regulate F13A reduce RER in mice, with a decrease of glucose oxidation and an increase of lipid oxidation in vivo.


Sign in / Sign up

Export Citation Format

Share Document