scholarly journals Identification of Tuberculosis Patient Characteristics Using K-Means Clustering

2016 ◽  
Vol 3 (2) ◽  
pp. 129-138
Author(s):  
Betha Nur Sari
Keyword(s):  
Patient Characteristics ◽  
Tuberculosis Patient ◽  
Major Health ◽  
Tuberculosis Patients ◽  
Pulmonary Tb ◽  
Results Of Treatment ◽  
Silhouette Coefficient ◽  
The World ◽  
Extra Pulmonary ◽  
Gene Shaving

In Indonesia, tuberculosis remains one of the major health problems unresolved. Indonesia is second ranked in the world as the country with the most tuberculosis cases. The purpose of this research is to study how K-means clustering applied to the treatment of tuberculosis patients data in order to identify the characteristics of tuberculosis patients. The results of K-means clustering validated by gene shaving and silhoutte coefficient. The experiment results indicate the optimum clusters value obtained from the K-mean clustering that has been validated by gene shaving and silhouette coefficient. K-means clustering divided four groups of tuberculosis patients based on their characteristics. There were divided at a category of disease (pulmonary TB, Extra Pulmonary TB and both), the age of the patient and the results of treatment of tuberculosis.

scholarly journals Association of type of tuberculosis with treatment outcome among paediatric tuberculosis patients in Bhopal city

2017 ◽  
Vol 4 (11) ◽  
pp. 4205
Author(s):  
Sheloj Joshi
Keyword(s):  
Treatment Outcome ◽  
Age Groups ◽  
Study Data ◽  
Age Group ◽  
Tuberculosis Patients ◽  
Pulmonary Tb ◽  
Paediatric Patients ◽  
Immunodeficiency Virus ◽  
Extra Pulmonary ◽  
Paediatric Tuberculosis

Background: Tuberculosis causes ill-health among millions of people each year and ranks as the second leading cause of death from an infectious disease worldwide, after the human immunodeficiency virus (HIV).The younger the child, the more are the chances of complications and death from the disease. The objective of the study was to find out the association of type of tuberculosis with the treatment outcome of paediatric TB patients registered under RNTCP in Bhopal city.Methods: A longitudinal study was conducted in all tuberculosis treatment units (TU) of Bhopal city. All paediatric patients in the age group of 0 to 14 years diagnosed as TB and registered under RNTCP and fulfilling inclusion criteria during January 2013 to June 2013 were included in the study. Data regarding paediatric TB patients was collected by using a structured questionnaire. Information was also obtained in two subsequent visits of the patient, one at the end of intensive phase to know the response of treatment and other at the end of the treatment for treatment outcome. The data was analysed on statistical software SPSS vs.20.Results: The present study was conducted on 165 paediatric Tuberculosis patients who were registered for DOTS treatment under RNTCP. Pulmonary TB is common in all the age group of <1 and 1-10 years. Out of 165 paediatric patients,93.33% of patients were treatment completed in which 54.54% were pulmonary cases and 45.45% were extra pulmonary while 4.84% were declared cured, thus showing statistically significant association (X2=9.758 and p=0.04, df=4) between type of Tuberculosis and treatment outcome.Conclusions: Pulmonary TB is common in the age groups of <1 and 1-10 years while in 11-14 years of age group extra pulmonary TB is more common. There is statistically significant association between type of Tuberculosis and treatment outcome. 

scholarly journals Evaluation of Anti-TBGL Antibody in the Diagnosis of Tuberculosis Patients in China

2015 ◽  
Vol 2015 ◽  
pp. 1-9 ◽  
Author(s):  
Jingge Zhao ◽  
Zhaoqin Zhu ◽  
Xiaoyan Zhang ◽  
Yasuhiko Suzuki ◽  
Haorile Chagan-Yasutan ◽  
...  
Keyword(s):  
Cell Wall ◽  
Health Care Workers ◽  
Healthy Controls ◽  
Exposure Risk ◽  
Tuberculosis Patients ◽  
Pulmonary Tb ◽  
Care Workers ◽  
Antibody Titers ◽  
Extra Pulmonary

Tuberculous glycolipid (TBGL) is a component of the Mycobacterium tuberculosis cell wall, and anti-TBGL antibodies are used for serodiagnosis of tuberculosis. Anti-TBGL IgG and IgA levels were measured in 45 pulmonary TB patients (PTB), 26 extra-pulmonary TB patients (ETB), 16 AIDS-TB patients, and 58 healthy controls (HC) including 39 health care workers (HW) and 19 newly enrolled students (ST). Anti-TBGL IgG measurements yielded 68.9% and 46.2% sensitivity in PTB and ETB, respectively, and 81.0% specificity. However, anti-TBGL IgA measurements were significantly less sensitive in detecting ETB than PTB (15.4% versus 46.7% sensitivity) but showed up to 89.7% specificity. Samples from AIDS-TB patients exhibited low reaction of anti-TBGL IgG and IgA with 6.3% and 12.5% sensitivity, respectively. Unlike anti-lipoarabinomannan (LAM) IgG that was found to elevate in sputum smearpositive subjects, anti-TBGL IgG and IgA elevated in those with cavitation and bronchiectasis, respectively. Anti-TBGL IgG in cavitary TB yielded 78.2% sensitivity compared to 57.1% in those otherwise. Meanwhile, higher anti-TBGL IgA titers were observed in HW than in ST, and increasing anti-TBGL IgG titers were observed in HW on follow-up. Therefore, higher anti-TBGL antibody titers are present in patients presenting cavities and bronchiectasis and subjects under TB exposure risk.

scholarly journals Hubungan Pelaksanaan Strategi Directly Observed Treatment Short Course dengan Hasil Pengobatan Tuberkulosis Paru Puskesmas Padang Pasir Kota Padang 2011-2013

2015 ◽  
Vol 4 (1) ◽  
Author(s):  
Nurmadya Nurmadya ◽  
Irvan Medison ◽  
Hafni Bachtiar
Keyword(s):  
Pulmonary Tuberculosis ◽  
Statistical Tests ◽  
Treatment Success ◽  
Study Data ◽  
P Value ◽  
Chi Square ◽  
Cross Sectional ◽  
Pulmonary Tb ◽  
Results Of Treatment ◽  
The World

AbstrakTuberkulosis (TB) paru masih menjadi masalah utama kesehatan global di dunia. Pada tahun 2011, Indonesia berada di posisi keempat dengan jumlah penderita TB terbanyak di dunia. Dalam upaya penanggulangan TB, Indonesia telah mengadopsi strategi DOTS sejak tahun 1995. Berdasarkan laporan tahunan Dinas Kesehatan Kota Padang tahun 2011, angka keberhasilan pengobatan di Puskesmas Padang Pasir yaitu 71,43% dan angka ini belum mencapai target nasional. Penelitian ini bertujuan untuk mengetahui hubungan pelaksanaan strategi DOTS dengan hasil pengobatan TB paru di Puskesmas Padang Pasir Kota Padang. Jenis Penelitian ini adalah analitik dengan desain cross sectional study. Data dikumpulkan melalui wawancara kepada responden menggunakan kuisioner yang kemudian di analisis melalui uji Chi-Square. Hasil uji statistik Chi-Square menunjukkan adanya hubungan antara pelaksanaan komitmen oleh petugas kesehatan (p-value : 0,000), pelaksanaan pemeriksaan dahak (p-value: 0,005, ketersedian OAT (p-value : 0,002) dengan hasil pengobatan TB paru. Hasil uji statistik pada peranan PMO (p-value : 0,185) dan pencatatan pelaporan penderita TB paru (p-value 0,184) menunjukkan tidak terdapat hubungan dengan hasil pengobatan TB paru.Kata kunci: tuberkulosis paru, DOTS, hasil pengobatanAbstractTuberculosis (TB) remains a major problem pulmonary global health in the world. In 2011, Indonesia was in fourth position with the highest number of TB patients in the world. InTB controlefforts, Indonesia hasadopted theDOTS strategysince 1995.Based on the annual report of Padang City Health Department in 2011, the treatment success rate in Padang Pasir Health Center is 71.43% and this figure has not reached the national target. The study aims to determine the relationship implementation of the DOTS strategy with pulmonary TB treatment success in health centers Padang Padang Pasir.This type of study design was cross-sectional analytic study. Data were collected through interviews with respondents using a questionnaire which was then analyzed by chi-square test. The results of the chi -square statistical tests showed that the implementation of commitments by health workers (p - value: 0.000), the implementation of sputum examination (p - value : 0.005), availability of OAT (p - value : 0.002) have a correlation with the results of treatment of pulmonary tuberculosis . While results statistical tests on the role of the PMO (p - value : 0.185) reporting and recording of pulmonary TB patients (p– value : 0.184) showed there was no correlation with the results of treatment of pulmonary tuberculosis.Keywords: pulmonary tuberculosis, DOTS, treatment success

scholarly journals Patient Characteristics Associated with Different Types of Prison TB: An Epidemiological Analysis of 921 TB Cases Diagnosed at an Ethiopian Prison

2021 ◽  
Author(s):  
Asmah Amirkhani ◽  
Maheen Humayun ◽  
Wen Ye ◽  
Yoseph Worku ◽  
Zhenhua Yang
Keyword(s):  
General Population ◽  
Patient Characteristics ◽  
World Health ◽  
Control Treatment ◽  
Pulmonary Tb ◽  
Hiv Coinfection ◽  
Increased Risk ◽  
Different Types ◽  
Extra Pulmonary ◽  
Over Time

Abstract Background: Despite incarcerated population being at an increased risk of tuberculosis (TB) and serving as a potential source of TB transmission for the general population, prison TB remains understudied. Given its adverse impact on progress towards TB elimination, World Health Organization (WHO) has identified prison TB research as a top priority to guide TB treatment/control interventions. Methods: We retrospectively analyzed 921 notified TB cases that were diagnosed at Kality Federal Prison, Ethiopia during 2009-2017. To assess trends of microbiologically confirmed pulmonary TB (PTB), extra-pulmonary TB (EPTB), and TB-HIV co-infection, an ecological analysis of aggregated cases was used to report trends over time. Additionally, we used multivariable log binomial regression to identify patient characteristics associated with microbiologically confirmed PTB, extra-pulmonary TB (EPTB), and TB-HIV co-infection. Results: Microbiologically confirmed PTB proportion increased over time. Young age was identified as an important risk factor for EPTB (aPR=1.74, 95%CI: 0.97, 3.13) while HIV coinfection was negatively associated with EPTB (aPR=0.73, 95%CI: 0.55, 0.97). While previous TB history was associated with a lower likelihood of EPTB (aPR=0.42, 95%CI:0.25, 0.70), it was associated with an increased risk of TB-HIV coinfection (aPR=1.37, 95%CI:1.10, 1.71). Clinically diagnosed PTB patients were more likely to have TB-HIV coinfection compared to microbiologically confirmed PTB patients (aPR= 1.32, 95%CI: 1.02, 1.72).Conclusions: Increasing proportion of microbiologically confirmed PTB may suggest delayed access to treatment, severe disease and increased risk of intramural transmission. Associations with clinical/demographic factors varied for different types of TB and were not always consistent with what has been previously reported for the general population, necessitating the need to refocus prison TB control/treatment strategies based on context specific epidemiological factors.

scholarly journals Relationship between the Role of Nursing Educators with Compliance and Lung Tuberculosis Control Patients in Medika Mulia Hospital

2020 ◽  
Vol 3 (2) ◽  
pp. 52
Author(s):  
Citra Dewi Ayu Trisnawati
Keyword(s):  
Tuberculosis Patient ◽  
Compliance Control ◽  
Cross Sectional ◽  
Nursing Educators ◽  
Tuberculosis Patients ◽  
Pulmonary Tb ◽  
Lung Tuberculosis ◽  
Close Relationship ◽  
Role Of Nursing

<em>The compliance control of Lung Tuberculosis patients to Poli Paru is influenced by several factors one of which is the Hospital environmental factors (doctors, nurses, midwives, and other health teams). Nurses are a profession very close to patients, one of the approaches used by nurses is the role of the nurse as an Educator. The purpose of this study was to know the relationship between the role of the Nurse Educator with the compliance control of pulmonary tuberculosis patients in Medika Mulia Hospital, Tuban. The method used in this research was the correlation analytic method with a cross-sectional research design. The research in this study involved 66 pulmonary TB patients in Pulmonary Medika Mulia Hospital of Tuban with the determination of the sample using a systematic random sampling method. Data collection was carried out by questionnaire using </em>Spearman rho<em> test data analysis. From the results of the analysis obtained data with a significance value of 0.003 (p &lt;0.05) which means there was a positive relationship between the role of Educator nurses with compliance with Lung Tuberculosis patient compliance. Therefore, HI was accepted, namely the close relationship between the role of the Educator nurse and the compliance control of Lung Tuberculosis patients in the Pulmonary Poli Medika Mulia Hospital, Tuban.</em><em> The results of this study provided input to nurses in the development of nursing knowledge, specifically the role of nurses as educators in the Pulmonary Poli Medika Mulia Hospital of Tuban to improve control compliance in pulmonary TB patients.</em>

scholarly journals A study of treatment outcomes of pulmonary tuberculosis and extrapulmonary tuberculosis patients in a tertiary care centre

2017 ◽  
Vol 4 (4) ◽  
pp. 1133 ◽  
Author(s):  
V. H. Ramya ◽  
G. Gayathri ◽  
V. Gangadharan
Keyword(s):  
Treatment Outcome ◽  
Success Rate ◽  
Treatment Outcomes ◽  
Tertiary Care ◽  
Care Centre ◽  
Cure Rate ◽  
Tertiary Care Centre ◽  
Tuberculosis Patients ◽  
Pulmonary Tb ◽  
Extra Pulmonary

Background: Directly observed treatment remains one of the most widely-accepted global health interventions for tuberculosis. Tuberculosis treatment outcome is one of the performance indicators of the programme set by World Health Organization.Methods: This study was conducted in a tertiary care centre Chennai. A retrospective analysis of the profile and treatment outcome of all tuberculosis patients registered from January 2015 to December 2015 at DOTS centre under RNTCP was conducted. Data on treatment outcomes was analysed using appropriate statistical methods and percentages were calculated.Results: Out of 118 TB cases, 59.3% had pulmonary while 40.7% had extra-pulmonary TB. Sputum positive PTB is more common than sputum negative which is 74.2% and 25.8% respectively. Frequency of TB lymphadenitis is being the common presentation among extra pulmonary TB cases, followed by TB pleurisy. Success rate (cure rate plus treatment completion rate) for new cases was 63.1% and for retreatment cases was 36.9% while the overall success rate was 81%.Conclusions: Effective measures have to be taken in the programme to move forward to help in the eradication of TB. Tuberculosis mostly affects males of the economically productive age group and causes economic losses. The success rate of new cases was higher compared to retreatment cases though the overall success rate was lower compared to the RNTCP norms. Proper education on DOTS can help in improving the success rate and cure rate.

scholarly journals Diagnostic Challenge Of Peritoneal Tuberculosis In Woman With Ascites

2020 ◽  
Vol 3 (1) ◽  
pp. 49
Author(s):  
Nenci Siagian ◽  
Muhammad Vitanata Arfijanto
Keyword(s):  
Case Report ◽  
Extrapulmonary Tuberculosis ◽  
Peritoneal Tuberculosis ◽  
Diagnostic Challenge ◽  
Major Health ◽  
Pulmonary Tb ◽  
Radiologic Examination ◽  
Global Issue ◽  
The World ◽  
The One

Tuberculosis (TB) is a major health global issue including extrapulmonary tuberculosis (EPTB). The one of manifestation of EPTB is peritoneal TB that constitutes 2% from all cases of pulmonary TB around the world. The diagnosis of peritoneal TB is quite challenging because many cases have symptom that similar to other diseases and those often necessary need further specific examinations such as PCR, culture and radiologic examination. We reported a case report of peritoneal tuberculosis in woman with ascites.

Kebutuhan Psikososial Keluarga yang Mempunyai Anggota Keluarga MenderitaTB Paru

1970 ◽  
Vol 3 (1) ◽  
Author(s):  
Noor Indyah Rachmawati ◽  
Suryani S ◽  
Chandra Isabella
Keyword(s):  
Pulmonary Tuberculosis ◽  
Public Health Problem ◽  
Sampling Technique ◽  
Treatment Programs ◽  
Psychosocial Needs ◽  
Tuberculosis Patients ◽  
Pulmonary Tb ◽  
Healthy Environment ◽  
The World ◽  
Development Goals

TB paru masih menjadi masalah kesehatan di Indonesia dan dunia. Upaya pengendalian TB paru menjadi perhatian dunia dan menjadi salah satu indikator dalam pencapaian tujuan pembangunan global. Peran keluarga dalam pengobatan TB paru sangat besar yaitu sebagai PMO, pemberi dukungan psikis dan menciptakan lingkungan yang sehat untuk mencegah penularan. Keluarga yang mempunyai anggota keluarga menderita TB paru sering mendapat stigma negatif sehingga bisa menyebabkan kegagalan dalam merawat pasien. Penelitian ini dilakukan untuk mengetahui gambaran kebutuhan psikososial keluarga yang mempunyai anggota keluarga menderita TB Paru di RS X. Jenis penelitian deskriptif kuantitatif dengan total sampling keluarga pasien TB Paru yang sedang dirawat sebanyak 57 orang. Hasil penelitian menunjukkan bahwa seluruh responden membutuhkan kebutuhan psikososial yang meliputi kebutuhan interaksi sosial, emosi, pengetahuan dan spiritual. Kebutuhan psikososial yang paling banyak dibutuhkan adalah dalam hal pengetahuan. Hal ini menunjukkan bahwa pengetahuan sangat berpengaruh terhadap peran keluarga sebagai PMO dan dalam merawat anggota keluarganya yang menderita TB paru. Kebutuhan dengan nilai persentase tertinggi adalah dalam hal spiritual pada item adanya harapan untuk kesembuhan anggota keluarga yang menderita TB paru. Berdasarkan hasil penelitian ini, diharapkan RS X berupaya meningkatkan pemenuhan kebutuhan psikososial keluarga, dengan cara menambah frekuensi penyuluhan, mengembangkan metode pemberian informasi untuk menguatkan pengetahuan atas informasi yang diberikan, kemudahan konsultasi dengan teknik konseling dapat diberikan untuk meningkatkan pengetahuan dan partisipasi keluarga dalam program pengobatan. Kata kunci: Kebutuhan psikososial, keluarga, TB Paru. Family’s Psychosocial Needs of Pulmonary Tuberculosis Patients AbstractPulmonary TB is still a public health problem in Indonesia and the world. Efforts in controlling TB desease are becoming a focus of the world and become one of the indicators in achieving global development goals. A families roles in TB treatment is very important as Supervisors to take medicine, giving psychological support and create a healthy environment to prevent desease spread. A family that has a member with TB desease oftenly receaved negative stigma hance it could result in treatment failure. This study was conducted to describe family’s psychosocial needs among pulmonary tuberculosis patients at X Hospital. This study is descriptive quantitative, using total sampling technique with family respondents pulmonary TB patients are being cared for as many as 57 people. The results showed that all respondents required psychosocial needs include the need for social interaction, emotional, knowledge and spiritual. This shows that the knowledge is very influential toward a families roles as Supervisor to take medicine and in caring for family members who suffer from tuberculosis. Needs with the higest percentage in terms of spiritual item is hope to recover from TB. Based on these results, it is expected X Hospital seeks to improve the fulfillment of the families psychosocial needs by way of to increase the frequency of health information, developed a method of providing information to strengthen knowledge on the information provided, ease of consultation with counseling techniques can be given to increase family participation in treatment programs. Key words: Family, psychosocial needs, pulmonary TB.

scholarly journals Analysis on Factors Related with Treatment Behavior of Pulmonary Tuberculosis Patient

2018 ◽  
Vol 14 (1) ◽  
pp. 81-89
Author(s):  
Nita Yunianti Ratnasari ◽  
Susana Nurtanti
Keyword(s):  
Pulmonary Tuberculosis ◽  
Health Center ◽  
Tuberculosis Patient ◽  
High Rate ◽  
Primary Data ◽  
Patient Treatment ◽  
District Health ◽  
Cross Sectional ◽  
Tuberculosis Patients ◽  
Pulmonary Tb

The total number of pulmonary tuberculosis cases found in Wonogiri district up to Trimester III in 2017 was 602 new cases. Adherence to patient treatment is one of the decisive factors in the success of therapy, but adherence to treatment by pulmonary TB patients is often low. This study aims to evaluate the compliance of treatment of pulmonary tuberculosis patients in Selogiri District Health Center Wonogiri regency. The design of this study used cross-sectional descriptive analysis with data collector in the form of questionnaire as primary data and patient treatment card (Form TB 01) as secondary data. Population of all pulmonary TB patients treated at Selogiri Public Health Center, registered from January 2016 to December 2017. Sampling by total sampling technique. Result of research from 23 total respondents during treatment showed that the number of respondents who adhere to TB treatment was smaller than the non-compliant respondent, that is 10 respondents (43,47%) obedient while respondent did not obey 13 (56,52%). The conclusion of this study there is no relationship between sociodemographic factors, knowledge, drug side effects, history of other diseases, availability of transportation and the role of families and officers with compliance to treatment of pulmonary tuberculosis patients in Selogiri Health Center. This study shows the high rate of non-adherence treatment of lung TB patients.

scholarly journals Prevalence of Antibiotic Resistance to Isonicotinylhydrazide and Rifampicin in Culture Positive Pulmonary Tuberculosis Patients From 2014 to 2016 in Zahedan City, Iran

2019 ◽  
Vol 4 (2) ◽  
pp. 57-61
Author(s):  
Seyed Mohammad Hashemi Shahri ◽  
Fatemeh Fardoust ◽  
Shokoufeh Mogharabi Ostad Kalayeh ◽  
Mohammad Ghenaatpisheh Sanani
Keyword(s):  
Antibiotic Resistance ◽  
Pulmonary Tuberculosis ◽  
Positive Culture ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Tuberculosis Patients ◽  
Pulmonary Tb ◽  
The World ◽  
Culture Positive

Background: One third of the world’s population is infected with TB, and the disease is known as the second deadly global infection, even more severe than measles. The disease kills about 2 million people a year. Approximately 8 million people in the world are affected by advanced tuberculosis (TB). Objective: The current study aimed to determine the frequency of resistance to the antibiotics isoniazid and rifampin in positive culture pulmonary TB patients in Zahedan city during 2013-2016. Methods: This descriptive cross-sectional study studied 100 samples from patients who referred to Boo-Ali hospital of Zahedan city from 2014 to 2016. First, the isoniazid solution was prepared, and then the rifampin solution was prepared. After that, 200 μL of mycobacterium suspension was added to the antibiotic and antibiotic-free control. Results: Of 100 patients participating in the study, 50 (50%) were male and 50 (50%) were female. Participants had an average age of 51.69 ± 20.41 years (95-12 years), 79 (79%) were Iranians and 21 (21%) were Afghans. Of the 100 samples, 55 (55%) were from the year 2013, 21 (21%) were from 2014, 10 (10%) were from 2015, and 14 (14%) were from year 2016. The samples examined showed that 4 (4%) were resistant and 96% were sensitive. Conclusion: The results of the current study showed that out of 100 samples, 4 cases (4%) had resistance and 96% were sensitive; 2% were resistant to isoniazid, and 2% were resistant to isoniazid and rifampin.

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