Appearance of the Hymen at Birth and One Year of Age: A Longitudinal Study

PEDIATRICS ◽  
1993 ◽  
Vol 91 (4) ◽  
pp. 820-825
Author(s):  
Abbey B. Berenson

The increase in the number of prepubertal girls who require evaluation of possible sexual abuse creates a need for detailed information, not previously available from cross-sectional studies, on the influence of aging on the hymen's appearance. This study was undertaken to evaluate and document, using a longitudinal design, changes in the hymen's morphology in 62 girls without a history of sexual abuse between birth and their first birthday. Labial agglutination extensive enough to obscure the inferior half of the hymen was observed in 5 girls (8%) at 1 year of age. Thirty-three (58%) of the remaining 57 infants experienced a marked decrease in the amount of their hymenal tissue between birth and 1 year. Significantly more infants at 1 year of age had a crescentic configuration (0% vs 28%), and significantly fewer had an external ridge (82% vs 14%) as compared to the newborn period. An annular hymen with a central or ventrally displaced opening progressed to a crescentic hymen in 13 children by 1 year, 77% (10/13) of whom were observed to have a notch (cleft) at the 12 o'clock position on the earlier study. A superior notch appeared for the first time in 9 girls. Lateral notches resolved in 5 cases and persisted in 2. Inferior notches between the 4 and 8 o'clock positions were not observed at birth or 1 year. Hymenal tags resolved in 2 instances, persisted in the same location in 2, and appeared for the first time in 4 cases. Three girls had a hymenal mound (bump) at 1 year, all of which could be traced back to a similar finding at birth. No change in the number of infants with longitudinal intravaginal ridges was observed. Clinicians should be aware of the influence of age and changing estrogen levels on the hymen's morphology in order to differentiate normal anatomical from posttraumatic or infectious changes.

2020 ◽  
Vol 31 (2) ◽  
pp. 33-44
Author(s):  
Simon Francis ◽  
Obadia V. Nyongole

Background: The incidence of prostate cancer in Tanzania is among the highest recorded in Africa. Prostate cancer is also the most common cancer among men aged 50 years and above in Tanzania. Our study aimed to determine the awareness, knowledge, and attitudes among adult men with age 50 years and above regarding prostate cancer.Methods: This was a cross-sectional study that included 250 adult men aged 50 years and above in Lindi municipal being purposively selected and we interviewed them by using a structured questionnaire. A stratified random sampling method was used for obtaining our participants. All men who had stayed for not less than one year in Lindi and willing to participate were enrolled in the study. These men were selected at households without screening whether or not they had taken prostate screening test or had been diagnosed with prostate cancer Quantitative data were cleaned and analyzed with SPSS version 20.Results: Majority, 216(86.7%) of our study participants were aged 50–69 years and most of them, 142(56.8%) had primary education with 93.2% of them being married. Among the study subjects 7.2% had positive family history of cancer and 195(78%) were aware of prostate cancer with source of information being mass media (62.6%). Majority of them, 63.2%, did not know the risk age group. Few, 20.8% of our participants had good knowledge while majority, 95.2% had negative attitude toward prostate cancer. We found a statistically significant association between level of education, family history and level of knowledge regarding prostate cancer with p < 0.005.Conclusion: This study revealed high level of awareness, but poor knowledge regarding prostate cancer and negative attitude toward prostate cancer among men with age ≥50 years in Lindi municipal Tanzania. Key words: Awareness, knowledge, attitude, prostate cancer.


Author(s):  
Zhijun Zou ◽  
Wei Liu ◽  
Chen Huang ◽  
Chanjuan Sun ◽  
Jialing Zhang

Background: Associations of early antibiotics exposures with childhood asthma, allergies, and airway illnesses are debated. Objectives: We aimed to investigate associations of first-year antibiotics exposure with childhood asthma, allergies, and airway illnesses. Methods: A cross-sectional study was conducted among preschoolers in Shanghai, China during 2011–2012. A questionnaire regarding household environment and lifestyles and childhood health outcomes was reported by the child’s parents. Results: In total, 13,335 questionnaires (response rate: 85.3%) were analyzed and 3049 (24.1%) children had first-year antibiotics exposure. In the multivariate logistic regression analyses, first-year antibiotics exposure had significant associations with the higher odds of lifetime-ever pneumonia (adjusted OR, 95% CI: 2.15, 1.95–2.37), croup (1.46, 1.24–1.73), wheeze (1.44, 1.30–1.60), asthma (1.38, 1.19–1.61), food allergy (1.29, 1.13–1.46), and allergic rhinitis (1.23, 1.07–1.41), and as well as current (one year before the survey) common cold (≥3 times) (1.38, 1.25–1.52), dry cough (1.27, 1.13–1.42), atopic dermatitis (1.25, 1.09–1.43), wheeze (1.23, 1.10–1.38), and rhinitis symptoms (1.15, 1.04–1.26). These associations were different in children with different individual characteristics (age, sex, family history of atopy, and district) and other early exposures (breastfeeding, home decoration, pet-keeping, and environmental tobacco smoke). Conclusions: Our results indicate that first-year antibiotics exposure could be a strong risk factor for childhood pneumonia, asthma, allergies, and their related symptoms. The individual characteristics and other early exposures may modify effects of early antibiotic exposure on childhood allergies and airway illnesses.


2019 ◽  
Vol 6 (1) ◽  
pp. 12-15
Author(s):  
Ishrat Sharmin ◽  
AKM Quamruzzaman ◽  
Rezina Parveen ◽  
M Abdulah Yusuf ◽  
Rashida Akter Khanam

Background: Newly developed KAtex test can be used as a non invasive tool for diagnosis of Kala-azar. Objectives: The aim of the present study was to compare KAtex, Bone marrow aspiration and DAT to diagnose VL. Methodology: This cross-sectional study was carried out in the Department of Microbiology at Dhaka Medical College, Dhaka, Bangladesh in collaboration with the Department of Parasitology, Institute of Epidemiology, Disease Control and Research (IEDCR), Dhaka, Bangladesh for a period of one year. Clinically suspected Kala-azar (VL) cases of different age and sex attending IEDCR, Dhaka from different Kala-azar endemic areas of Bangladesh were selected for this study. Patients having fever for more than 2 weeks, with or without splenomegaly, having history of loss of body weight following onset of fever were clinically suspected as Kala-azar cases. Microscopy and culture was performed in bone marrow (BM). KAtex was performed with urine sample. Agglutination of sensitized latex indicated presence of Leishmania donovani antigen in urine and thereby visceral leishmaniasis. No agglutination indicates absence of antigen in urine. DAT was done with serums of all cases. Result: Among 130 clinically suspected VL cases, 70 (53.85%) cases were BM positive and 60(46.15%) cases were BM negative. All the 70 BM positive cases were positive by KAtex and DAT. Among 60 BM negative cases, 15 were positive by KAtex and 23 were positive by DAT. The sensitivity of KAtex was 100.0% and specificity was 75.0%. The sensitivity of DAT was 100.0% and specificity is 61.6%. Conclusion: In conclusion, KAtex test is a good diagnostic tool for the detection of VL in comparison with DAT. Bangladesh Journal of Infectious Diseases, June 2019;6(1):12-15


Author(s):  
Seha Akduman

Aim: In this retrospective crossectional study, it was aimed to evaluate the development of COPD in terms of urea, creatinine and some blood parameters in patients with allergic rhinitis. Method: Patients who were admitted to Kadıköy Medicana Hospital between 12.10.2017 and 12.10.2018 with respiratory complaints and has COPD diagnosis for the first time were evaluated retrospectively. Among the 845 patients admitted to the clinic for a one-year period, 160 patients with the diagnosis of COPD for the first time and 42 patients with a history of allergic rhinitis were subjected. The study group consisted of 63 patients with COPD who were diagnosed as COPD for the first time but without allergic rhinitis and 57 allergic rhinitis patients with no diagnosis of COPD. Findings: CRP, urea, WBC and neutrophil levels were higher in COPD group; creatinine and eisonofil levels were higher in COPD-Allergic rhinitis group and HGB was higher in the allergic rhinitis group. The differences between CRP and urea levels of COPD and allergic rhinitis group were statistically significant (p <0.05). The urea values were significantly different between COPD + allergic rhinitis and COPD groups (p <0.05). According to the results of ROC analysis, the value of urea for the COPD + allergic rhinitis group was statistically insignificant (p> 0.05), whereas it was statistically significant for the allergic rhinitis group (p <0.05). Conclusion: In detecting the difference between allergic rhinitis and COPD associated allergic rhinitis, urea levels may have a diagnostic value. An increase in urea in patients with allergic rhinitis may indicate comorbid COPD.


2019 ◽  
Vol 6 (8) ◽  
pp. 2941
Author(s):  
Anilkumar Bellad ◽  
Kartik Sahu

Background: One of the independent risk factor for erectile dysfunction is diabetes mellitus. The present study planned to determine the prevalence and factors associated with ED in DM.Methods: A one year cross-sectional study on a total of 208 patients with type 1 or 2 diabetes. National Institutes of Health (NIH) approved questionnaire for International Index of Erectile Function (IIEF) was used to interview each patient to assess for ED.Results: In this study 12.98% of patients had ED score between 13 to 18 suggestive of mild to moderate ED and 9.62% with 19 to 24 scores suggestive of mild degree. The prevalence of erectile dysfunction was 32.21%. The mean age in patients with erectile dysfunction was significantly high (58.40±10.96 years) compared to those without erectile dysfunction (51.00±11.16 years) (p<0.001) Of the 119 patients with duration of diabetes between one to five years 42.02% had ED and of the 3 patients with duration of more than five years 66.67% had ED (p<0.001). Prevalence of ED was higher in patients with HbA1c levels between 7.0 to 8.5 (32.76%) and >8.5 (37.07%). Prevalence of erectile dysfunction was higher in patients with history of smoking (63.64%) (p<0.001) and alcohol intake (51.85%) (p<0.001). The prevalence of erectile dysfunction was also significantly high in patients with history of hypertension (59.7%) (p<0.001).Conclusions: The ED in patients with diabetes mellitus was significantly prevalent with age, duration of diabetes, history of hypertension, cardiovascular disease, glycemic control and hypertriglyceridemia.


Viruses ◽  
2021 ◽  
Vol 13 (9) ◽  
pp. 1687 ◽  
Author(s):  
John Charles Rotondo ◽  
Fernanda Martini ◽  
Martina Maritati ◽  
Chiara Mazziotta ◽  
Giulia Di Mauro ◽  
...  

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a newly discovered coronavirus responsible for the coronavirus disease 2019 (COVID-19) pandemic. COVID-19 has rapidly become a public health emergency of international concern. Although remarkable scientific achievements have been reached since the beginning of the pandemic, the knowledge behind this novel coronavirus, in terms of molecular and pathogenic characteristics and zoonotic potential, is still relatively limited. Today, there is a vaccine, or rather several vaccines, which, for the first time in the history of highly contagious infectious diseases that have plagued mankind, has been manufactured in just one year. Currently, four vaccines are licensed by regulatory agencies, and they use RNA or viral vector technologies. The positive effects of the vaccination campaign are being felt in many parts of the world, but the disappearance of this new infection is still far from being a reality, as it is also threatened by the presence of novel SARS-CoV-2 variants that could undermine the effectiveness of the vaccine, hampering the immunization control efforts. Indeed, the current findings indicate that SARS-CoV-2 is adapting to transmission in humans more efficiently, while further divergence from the initial archetype should be considered. In this review, we aimed to provide a collection of the current knowledge regarding the molecular, phylogenetic, and pathogenetic insights into SARS-CoV-2. The most recent findings obtained with respect to the impact of novel emerging SARS-CoV-2 variants as well as the development and implementation of vaccines are highlighted.


2021 ◽  
Vol 15 (10) ◽  
pp. 3520-3523
Author(s):  
Muneeba Sadaf ◽  
Afshan Zaman ◽  
Fatima Bibi ◽  
Maria Tariq ◽  
Uzma Nayyer ◽  
...  

Objectives: To determine the frequency of asymptomatic bacteriuria in pregnantwomen. Study design: Descriptive, Cross sectional study Place and Duration: Department of Obstetrics & Gynaecology, Benazir Bhutto Hospital, Rawalpindi. 26th December 2017 to 25th June 2018 Materials & Methods: A total of 151 pregnant women of gestational age ≥28 weeks, 18 to 40 years of age were included. Patients with genital tract trauma, history of UTI in the past one year and urinary tract stones were excluded. Then clean-catch midstream urine was collected from each woman into a sterile universal container and sample was sent to the institutional laboratory for presenceor absence of asymptomatic bacteriuria. Results: Age range in this study was from 18 to 40 years with mean age of 28.78 ± 3.90 years. Majority of the patients 84 (55.63%) were between 18 to 30 years of age. Mean gestational age was 31.06 ± 1.67 weeks. Mean parity was 3.17 ± 0.99. Mean BMI was 27.44 ± 3.02 kg/m2. In our study, frequency of asymptomatic bacteriuria in pregnant women was found in 25 (16.56%) patients. Conclusion: This study concluded that frequency of asymptomatic bacteriuria in pregnant women is quite high. Keywords: Asymptomatic Bacteriuria, Pregnancy, Urinary Tract Infection.


2020 ◽  
Vol 26 (1) ◽  
pp. 41-60
Author(s):  
Sheraz Ali ◽  
Johar Ali

This study focuses on suicidal ideation in victims of sexual abuse. Drawing upon semi-structured interviews of thirty victims of sexual abuse in Khyber Pukhtunkhwah, Pakistan, this paper discusses the theme, i.e. domestic violence, including indiscriminate sexual abuse and the abhorring crime of incest, which remains hidden due to aggressively upheld patriarchal norms of women exploitation. The interviews conducted at six different locations, present women's narratives of their untold plight for the first time. The findings of this research show that among the respondents, only those women had strong suicidal ideations who were the victims of incest. Irritation, aggression and self-deprecating behaviour were strong symptoms of their suicidal temptations. Pain, physical and emotional, caused by overwhelming stress in the form of familial and social hatred, social disconnectedness, burdensomeness and the previous history of violence were the main factors that highly escalated their risk factor in committing suicide


1956 ◽  
Vol 18 (1) ◽  
pp. 9-31 ◽  
Author(s):  
George Makdisi

The Arabic manuscript which forms a part of Majmū‘ No. 17, preserved in the ຒahirīya Library in Damascus, is the only fragment extant of a diary kept during the fifth/eleventh century by a contemporary historian of Baghdad, Abū ’Alī b. al-Bannā’ al-Ḥanbalī. An edition and translation of this fragment (hereafter referred to as the Diary) are given here for the first time. It covers in some detail a period of slightly more than one year, from A.H. 460 to A.H. 461 (corresponding to A.D. 1068–69), in the socio-religious history of Baghdad.


2020 ◽  
Vol 11 (2) ◽  
pp. 86-90
Author(s):  
Rukhsana Parvin ◽  
Zakia Nahar ◽  
Merina Sultana ◽  
Md Golam Mowla ◽  
Tahira Salwa Jabbar ◽  
...  

Background: Though Bangladesh has done well to reduce the measles cases and measles related deaths through an effective vaccination programme, measles cases are still found in a good number in hospitals. The objectives of our study was to find out the vaccination status of laboratory confirmed measles patients and also to see the socio-demographic status of those patients. Methodology: This is a descriptive cross-sectional study conducted in five Upazilla Health Complexes (UHC) of Gazipur district during a period of one year from 01/01/2017 to 31/12/ 2017. The Upazillas included were Gazipur Sadar, Kaliganj, Kaliakair, Sreepur and Tongi. The suspected measles patients were admitted after taking history and clinical examination and confirmed by doing specific laboratory investigation. Measles vaccination status and sociodemographic status of the these confirmed cases were analysed by using SPSS version 21. Results: Blood samples were sent from 93 patients who were admitted during the study period after observing the diagnostic criteria of measles. Out of them 45 patients were confirmed as measles and they are included in the study. Among the laboratory confirmed measles, 28 cases (62.22%) were males and 17 (37.78%) cases were females, ratio of male and female was 1.6:1. The maximum number of patients (62.22%) were in the age group of 9 months to 4 years. Maximum patients came from low socioeconomic condition with a monthly income of 10,000- 15,000 taka. About maternal education, 26 mothers (57.78%) were uneducated, 12(26.67%) below primary and 7(15.55%) up or above primary level. Among the total patients, 27(60%) patients came with pneumonia, 16(35.56%) patients with both pneumonia and diarrhoea and 2(4.44%) patients only with diarrhoea. We found 32 patients (71.11%) received no MCV(Measles containing vaccine) , 11 patients (24.44%) with one MCV and 2 patients (4.44%) received two MCVs. There we found several causes of dropout of measles vaccine. Lack of awareness regarding one vaccine was the most common cause (42.22%) and then ignorance about two measles vaccine (28.89) followed by migration (17.78%) and parental occupation (11.11%). History of contact with measles patients were found in 24.44% cases , no history in 26.67% cases and in 48.89% cases the history of contact is unknown. J Shaheed Suhrawardy Med Coll, December 2019, Vol.11(2); 86-90


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