scholarly journals A súlyos akut légzőszervi szindrómát okozó koronavírus-2 (SARS-CoV-2) orvosilag releváns aspektusai állatokban

2021 ◽  
Vol 162 (5) ◽  
pp. 163-170
Author(s):  
Anna Valkó ◽  
Melinda Medgyaszai

Összefoglaló. A mikroszkóp felfedezése óta tudjuk, hogy az egymással szoros közelségben élő egyedeknek nem csupán a látható élőhelyük közös, hanem szemmel nem érzékelhető mikroorganizmusokat is megosztanak egymással, melyek bizonyos fokban adaptálódtak gazdáikhoz. Az emberek életterének bővülésével és ezzel párhuzamosan az állatok élőhelyének csökkenésével azonban új állatfajok kerülhetnek veszélyes közelségbe, ami következményes mikrobaátadással és az új gazdában a mikroba eltérő viselkedésével járhat. Feltételezhetően ez a jelenség vezetett a súlyos akut légzőszervi szindróma koronavírus-2 (SARS-CoV-2) kialakulásához, mely 2019-ben jelent meg először emberekben, és néhány hónap leforgása alatt milliókat fertőzött meg az egész világon. A pandémia leküzdéséhez és az újabb járványok megelőzéséhez minden lehetséges eszközt fel kell használni, ami együttműködést kíván a humánorvoslás és az állatgyógyászat, valamint az ökológiai, evolúciós és környezeti tudományok szakemberei között a globális „Egy Egészség” keretében. A közös célok érdekében történő összefogás jegyében a jelen tanulmány állatorvos és humánorvos szerzőpárosa összefoglalja azon ismereteket, amelyek a SARS-CoV-2 vonatkozásában mindkét szakma számára érdemlegesek lehetnek. Bemutatásra kerül a vírus eredete, természetes és mesterséges előfordulása különböző állatfajokban, valamint az állati koronavírusokkal kapcsolatos azon tapasztalatok, amelyek hozzájárulhatnak a SARS-CoV-2 működésének megértéséhez és az ellene való védekezés tökéletesítéséhez. Orv Hetil. 2021; 162(5): 163–170. Summary. Introduction: Since the discovery of the microscope, we have known that individuals living in close proximity to each other share not only their visible habitat, but also invisible microorganisms that have adapted to some degree to their hosts. However, as human habitat expands and, in parallel, animal territory declines, new animal species can come into dangerous proximity, which may result in consequential transmission of microbes and different microbial behaviour in the new host. Presumably, this phenomenon led to the development of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which first appeared in humans in 2019 and infected millions over the course of a few months worldwide. All possible means must be used to combat the pandemic and prevent further epidemics, which will require cooperation between professionals in human medicine and veterinary medicine as well as in the ecological, evolutionary and environmental sciences, within the framework of the global “One Health”. In a spirit of working together for common goals, the authors of this study, a veterinarian and a human physician, summarize the knowledge that may be relevant to both professions for SARS-CoV-2. The origin of the virus, its natural and artificial occurrence in different animal species, and experiences with animal coronaviruses that may contribute to the understanding of the functioning of SARS-CoV-2 and the development of protection against it are presented. Orv Hetil. 2021; 162(5): 163–170.

2021 ◽  
Author(s):  
Rodolphe Mader ◽  
Clémence Bourély ◽  
Jean-Philippe Amat ◽  
Els M. Broens ◽  
Luca Busani ◽  
...  

AbstractBackgroundBuilding the European Antimicrobial Resistance Surveillance network in Veterinary medicine (EARS-Vet) was proposed to strengthen the European One Health antimicrobial resistance (AMR) surveillance approach.ObjectivesThe objectives were to (i) define the combinations of animal species, production types, age categories, bacterial species, specimens and antimicrobials to be monitored in EARS-Vet and to (ii) determine antimicrobial test panels able to cover most combinations.MethodsThe EARS-Vet scope was defined by consensus between 26 European experts. Decisions were guided by a survey of the combinations that are relevant and feasible to monitor in diseased animals in 13 European countries (bottom-up approach). Experts also considered the One Health approach and the need for EARS-Vet to complement existing European AMR monitoring systems coordinated by the European Centre for Disease Prevention and Control (ECDC) and the European Food Safety Authority (EFSA).ResultsEARS-Vet would monitor AMR in six animal species (cattle, swine, chicken (broiler and laying hen), turkey, cat and dog), for 11 bacterial species (Escherichia coli, Klebsiella pneumoniae, Mannheimia haemolytica, Pasteurella multocida, Actinobacillus pleuropneumoniae, Staphylococcus aureus, Staphylococcus pseudintermedius, Staphylococcus hyicus, Streptococcus uberis, Streptococcus dysgalactiae and Streptococcus suis). Relevant antimicrobials for their treatment were selected (e.g. tetracyclines) and complemented with antimicrobials of more specific public health interest (e.g. carbapenems). Three test panels of antimicrobials were proposed covering most EARS-Vet combinations of relevance for veterinary antimicrobial stewardship.ConclusionsWith this scope, EARS-Vet would enable to better address animal health in the strategy to mitigate AMR and better understand the multi-sectoral AMR epidemiology in Europe.


JAMIA Open ◽  
2020 ◽  
Vol 3 (2) ◽  
pp. 306-317
Author(s):  
Jonathan L Lustgarten ◽  
Ashley Zehnder ◽  
Wayde Shipman ◽  
Elizabeth Gancher ◽  
Tracy L Webb

Abstract Objectives This manuscript reviews the current state of veterinary medical electronic health records and the ability to aggregate and analyze large datasets from multiple organizations and clinics. We also review analytical techniques as well as research efforts into veterinary informatics with a focus on applications relevant to human and animal medicine. Our goal is to provide references and context for these resources so that researchers can identify resources of interest and translational opportunities to advance the field. Methods and Results This review covers various methods of veterinary informatics including natural language processing and machine learning techniques in brief and various ongoing and future projects. After detailing techniques and sources of data, we describe some of the challenges and opportunities within veterinary informatics as well as providing reviews of common One Health techniques and specific applications that affect both humans and animals. Discussion Current limitations in the field of veterinary informatics include limited sources of training data for developing machine learning and artificial intelligence algorithms, siloed data between academic institutions, corporate institutions, and many small private practices, and inconsistent data formats that make many integration problems difficult. Despite those limitations, there have been significant advancements in the field in the last few years and continued development of a few, key, large data resources that are available for interested clinicians and researchers. These real-world use cases and applications show current and significant future potential as veterinary informatics grows in importance. Veterinary informatics can forge new possibilities within veterinary medicine and between veterinary medicine, human medicine, and One Health initiatives.


Author(s):  
Athulya T. R. ◽  
Latha C. ◽  
Sunil B. ◽  
Deepa J. ◽  
Shynu M.

Campylobacteriosis caused by Campylobacter spp. is considered as the most common cause of bacterial diarrhoea in humans across the globe. The current research was undertaken to assess the occurrence of Campylobacter spp. in duck and the associated environmental samples. Among 220 samples analysed, 7.73 per cent samples revealed the presence of Campylobacter spp. Majority of the samples contained C. coli (4.55 per cent) and C. jejuni was detected in 3.18 per cent of the samples. The present study revealed a high occurrence of Campylobacter spp. in duck rearing facilities in Thrissur district, Kerala. As the demand for duck products is increasing every year, the risk of contamination by Campylobacter spp. has to be viewed seriously. The study revealed the importance of multifaceted one health approach including human medicine, veterinary medicine, epidemiology, environmental hygiene, public health institutes and epidemiological surveillance agencies to control food-borne diseases and up-gradation of biosecurity measures.


Author(s):  
Ken Peach

This chapter discusses the process of building research teams. Increasingly over the past three-quarters of a century, science has become a collective activity, with teams of tens, hundreds or even thousands of scientists, engineers and technicians working together on a common goal. Consequently, almost all research involves building, motivating and maintaining a research team. Even a theoretical group is likely to have one or two postdocs, graduate students and visitors, but research teams will, in addition, have engineers and technicians, as well as, possibly, research administrators. The chapter also addresses the importance of creating and maintaining a good team and team spirit, as large projects are assembled from a large number of small teams working on common goals, usually in a loose federated structure with some overall coordination and leadership.


Author(s):  
Andrea Springer ◽  
Antje Glass ◽  
Julia Probst ◽  
Christina Strube

AbstractAround the world, human health and animal health are closely linked in terms of the One Health concept by ticks acting as vectors for zoonotic pathogens. Animals do not only maintain tick cycles but can either be clinically affected by the same tick-borne pathogens as humans and/or play a role as reservoirs or sentinel pathogen hosts. However, the relevance of different tick-borne diseases (TBDs) may vary in human vs. veterinary medicine, which is consequently reflected by the availability of human vs. veterinary diagnostic tests. Yet, as TBDs gain importance in both fields and rare zoonotic pathogens, such as Babesia spp., are increasingly identified as causes of human disease, a One Health approach regarding development of new diagnostic tools may lead to synergistic benefits. This review gives an overview on zoonotic protozoan, bacterial and viral tick-borne pathogens worldwide, discusses commonly used diagnostic techniques for TBDs, and compares commercial availability of diagnostic tests for humans vs. domestic animals, using Germany as an example, with the aim of highlighting existing gaps and opportunities for collaboration in a One Health framework.


Animals ◽  
2021 ◽  
Vol 11 (7) ◽  
pp. 1941
Author(s):  
Igor V. Popov ◽  
Ammar Algburi ◽  
Evgeniya V. Prazdnova ◽  
Maria S. Mazanko ◽  
Vladimir Elisashvili ◽  
...  

One of the main problems in the poultry industry is the search for a viable replacement for antibiotic growth promoters. This issue requires a “one health” approach because the uncontrolled use of antibiotics in poultry can lead to the development of antimicrobial resistance, which is a concern not only in animals, but for humans as well. One of the promising ways to overcome this challenge is found in probiotics due to their wide range of features and mechanisms of action for health promotion. Moreover, spore-forming probiotics are suitable for use in the poultry industry because of their unique ability, encapsulation, granting them protection from the harshest conditions and resulting in improved availability for hosts’ organisms. This review summarizes the information on gastrointestinal tract microbiota of poultry and their interaction with commensal and probiotic spore-forming bacteria. One of the most important topics of this review is the absence of uniformity in spore-forming probiotic trials in poultry. In our opinion, this problem can be solved by the creation of standards and checklists for these kinds of trials such as those used for pre-clinical and clinical trials in human medicine. Last but not least, this review covers problems and challenges related to spore-forming probiotic manufacturing.


PEDIATRICS ◽  
1989 ◽  
Vol 84 (4) ◽  
pp. A96-A96
Author(s):  
J. F. L.

KENNETT SQUARE, Pa.—Nearly as rare as the colt that grows up to be a racing champion is the birth of twin foals. Yet a tiny and brave filly and her weaker twin brother grow stronger every day here in an intensive care unit for newborn horses. Established in 1983 and directed . . . by Dr. Wendy E. Vaala, a . . . veterinarian, the University of Pennsylvania's intensive care unit for foals was built. . . . It is one of only seven such units in the country, and they have led to the development of a new specialty in veterinary medicine—equine neonatology. Recipes for formula fed to foals were borrowed from those used at the University of Pennsylvania Hospital in Philadelphia. The intensive care unit uses ultrasound equipment, heart monitors and other devices commonly used in human neonatal medicine. Treatments for infections, poisoning, ulcers, birth defects, even difficult births were adopted from human medicine. . . . But there are no incubators. . . .The foals are too active.


Author(s):  
Marco BRANCUCCI

"Learning about freedom as freedom to make right choices responsibly is the pivotal task of educational intervention (Chionna 2001). As a practitioner of juvenile penitentiary re-education I experiment it, trying to re-educate young offenders in a prison, where the “capability approach” should be invoked (Sen 2011) and, according to the relational ethics paradigm (Muschitiello, 2012), we teach the young the capacity/ability of choice between alternative life experiences, which should be inspired and embodied by the educational authority of the adults. As agency is a constitutive element of a capability, I wonder: who is the agent? The one who re-educates an inmate? Or the inmate himself? Who should be more efficient and responsible to act in prison? Is it all about specific required competencies that are influenced by the context where penitentiary personnel and inmates act/react reciprocally? Penitentiary educators should adjust their approach, improving their language-as-dialogue tools first, just because the relationship with inmates is based on a dialogic axis. No exception can be made for cultural and linguistic mediators, who are involved in the treatment of foreign inmates (Brancucci 2018). So, I investigate the agency level of penitentiary educators and cultural/linguistic mediators, working together synergistically and/or autonomously. They try to respond to different scenarios, recognizing there is no one-size -fits-all approach to managing cases of re-educational emergencies, and assuming that educational interventions recall a daily presence in the context (Bertolini 1993), especially in prison where people ‘live’ in close proximity (WHO, 2020). But, how to achieve agency when this proximity fades away, or is temporarily interrupted, even turning into a virtual telematic educational approach? The challenge is to transform the consolidated educational-linguistic-dialogic practices into a new bidirectional way to think, act/react (from prison personnel towards inmates and vice-versa), because of the social distance required by the COVID-19 breakthrough."


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