Silicon Nanowire Integrated Electrolyte-Insulator-Semiconductor Sensor with an Above-Nernstian Sensitivity for Bio-Sensing Applications

2012 ◽  
Vol 1439 ◽  
pp. 127-132 ◽  
Author(s):  
Jin Yong Oh ◽  
Hyun-June Jang ◽  
Won-Ju Cho ◽  
Nezih Pala ◽  
M. Saif Islam
Keyword(s):  
Surface Area ◽  
Silicon Nanowire ◽  
Ph Sensitivity ◽  
Wet Etching ◽  
Si Nanowires ◽  
Etching Technique ◽  
Semiconductor Sensor ◽  
Sensing Applications ◽  
Highly Sensitive ◽  
Extended Surface

ABSTRACTHighly sensitive electrolyte-insulator-semiconductor (EIS) sensors were realized by the integration of Si nanowires (NWs), which were fabricated by using a simple and economic electroless wet etching technique. EIS sensors with NWs longer than 1 μm were observed to have considerably increased capacitance and high pH sensitivity. The pH sensitivity of the EIS sensor with 3.8 μm long NWs was 60.2 mV/pH, which is higher than the theoretical Nernstian of 59 mV/pH. The EIS sensors with NWs exhibited slightly worse pH hysteresis and drift properties than that of the conventional planar type EIS sensor. The increases in pH sensitivity, hysteresis and drift are attributable to the extended surface area of the EIS sensors enabled by the NWs.

scholarly journals Optically transparent vertical silicon nanowire arrays for live-cell imaging

2021 ◽  
Vol 19 (1) ◽  
Author(s):  
Roey Elnathan ◽  
Andrew W. Holle ◽  
Jennifer Young ◽  
Marina A. George ◽  
Omri Heifler ◽  
...  
Keyword(s):  
High Efficiency ◽  
Silicon Nanowire ◽  
Live Cell ◽  
Si Nanowires ◽  
Contrast Imaging ◽  
Silicon Nanowire Arrays ◽  
Transparent Substrate ◽  
Optically Transparent ◽  
Vertically Aligned

AbstractProgrammable nano-bio interfaces driven by tuneable vertically configured nanostructures have recently emerged as a powerful tool for cellular manipulations and interrogations. Such interfaces have strong potential for ground-breaking advances, particularly in cellular nanobiotechnology and mechanobiology. However, the opaque nature of many nanostructured surfaces makes non-destructive, live-cell characterization of cellular behavior on vertically aligned nanostructures challenging to observe. Here, a new nanofabrication route is proposed that enables harvesting of vertically aligned silicon (Si) nanowires and their subsequent transfer onto an optically transparent substrate, with high efficiency and without artefacts. We demonstrate the potential of this route for efficient live-cell phase contrast imaging and subsequent characterization of cells growing on vertically aligned Si nanowires. This approach provides the first opportunity to understand dynamic cellular responses to a cell-nanowire interface, and thus has the potential to inform the design of future nanoscale cellular manipulation technologies.

scholarly journals Highly Sensitive and Selective Sodium Ion Sensor Based on Silicon Nanowire Dual Gate Field-Effect Transistor

Sensors ◽  
2021 ◽  
Vol 21 (12) ◽  
pp. 4213
Author(s):  
Seong-Kun Cho ◽  
Won-Ju Cho
Keyword(s):  
Field Effect ◽  
Field Effect Transistor ◽  
Silicon Nanowire ◽  
Silicon On Insulator ◽  
Sodium Ion ◽  
Ion Sensor ◽  
Highly Sensitive ◽  
Selective Membrane ◽  
Dual Gate ◽  
Effect Transistor

In this study, a highly sensitive and selective sodium ion sensor consisting of a dual-gate (DG) structured silicon nanowire (SiNW) field-effect transistor (FET) as the transducer and a sodium-selective membrane extended gate (EG) as the sensing unit was developed. The SiNW channel DG FET was fabricated through the dry etching of the silicon-on-insulator substrate by using electrospun polyvinylpyrrolidone nanofibers as a template for the SiNW pattern transfer. The selectivity and sensitivity of sodium to other ions were verified by constructing a sodium ion sensor, wherein the EG was electrically connected to the SiNW channel DG FET with a sodium-selective membrane. An extremely high sensitivity of 1464.66 mV/dec was obtained for a NaCl solution. The low sensitivities of the SiNW channel FET-based sodium ion sensor to CaCl2, KCl, and pH buffer solutions demonstrated its excellent selectivity. The reliability and stability of the sodium ion sensor were verified under non-ideal behaviors by analyzing the hysteresis and drift. Therefore, the SiNW channel DG FET-based sodium ion sensor, which comprises a sodium-selective membrane EG, can be applied to accurately detect sodium ions in the analyses of sweat or blood.

scholarly journals Terahertz quantum sensing

2020 ◽  
Vol 6 (11) ◽  
pp. eaaz8065 ◽  
Author(s):  
Mirco Kutas ◽  
Björn Haase ◽  
Patricia Bickert ◽  
Felix Riexinger ◽  
Daniel Molter ◽  
...  
Keyword(s):  
Layer Thickness ◽  
Region Of Interest ◽  
Coherent Detection ◽  
Semiconductor Detectors ◽  
Terahertz Frequency ◽  
Sensing Applications ◽  
Highly Sensitive ◽  
Quantum Sensing ◽  
Thickness Measurements ◽  
Detection Schemes

Quantum sensing is highly attractive for accessing spectral regions in which the detection of photons is technically challenging: Sample information is gained in the spectral region of interest and transferred via biphoton correlations into another spectral range, for which highly sensitive detectors are available. This is especially beneficial for terahertz radiation, where no semiconductor detectors are available and coherent detection schemes or cryogenically cooled bolometers have to be used. Here, we report on the first demonstration of quantum sensing in the terahertz frequency range in which the terahertz photons interact with a sample in free space and information about the sample thickness is obtained by the detection of visible photons. As a first demonstration, we show layer thickness measurements with terahertz photons based on biphoton interference. As nondestructive layer thickness measurements are of high industrial relevance, our experiments might be seen as a first step toward industrial quantum sensing applications.

scholarly journals Hybrid Grating in Reduced-Diameter Fiber for Temperature-Calibrated High-Sensitivity Refractive Index Sensing

2019 ◽  
Vol 9 (9) ◽  
pp. 1923
Author(s):  
Biqiang Jiang ◽  
Zhen Hao ◽  
Dingyi Feng ◽  
Kaiming Zhou ◽  
Lin Zhang ◽  
...  
Keyword(s):  
Refractive Index ◽  
Simultaneous Measurement ◽  
Surrounding Medium ◽  
High Sensitivity ◽  
Fiber Grating ◽  
Bragg Resonance ◽  
Core Mode ◽  
Promising Alternative ◽  
Sensing Applications ◽  
Highly Sensitive

We propose and experimentally demonstrate a hybrid grating, in which an excessively tilted fiber grating (Ex-TFG) and a fiber Bragg grating (FBG) were co-inscribed in a reduced-diameter fiber (RDF). The hybrid grating showed strong resonances due to coupling among core mode and a set of polarization-dependent cladding modes. This coupling showed enhanced evanescent fields by the reduced cladding size, thus allowing stronger interaction with the surrounding medium. Moreover, the FBG’s Bragg resonance confined by the thick cladding was exempt from the change of the surrounding medium’s refractive index (RI), and then the FBG can work as a temperature compensator. As a result, the Ex-TFG in RDF promised a highly sensitive RI measurement, with a sensitivity up to ~1224 nm/RIU near the RI of 1.38. Through simultaneous measurement of temperature and RI, the temperature dependence of water’s RI is then determined. Therefore, the proposed hybrid grating with a spectrum of multi-peaks embedded with a sharp Bragg resonance is a promising alternative for the simultaneous measurement of multi-parameters for many RI-based sensing applications.

Study on the Manufacture of Microfluidic Chip with Coated Glass

2012 ◽  
Vol 548 ◽  
pp. 254-257 ◽  
Author(s):  
Yan He ◽  
Bai Ling Huang ◽  
Yong Lai Zhang ◽  
Li Gang Niu
Keyword(s):  
Microfluidic Chip ◽  
Low Cost ◽  
Microfluidic Channel ◽  
Critical Factor ◽  
Wet Etching ◽  
Microfluidic Chips ◽  
Etching Technique ◽  
Chip Quality ◽  
Wet Chemical ◽  
Wet Chemical Etching

In this paper, a simple and facile technique for manufacturing glass-based microfluidic chips was developed. Instead of using expensive dry etching technology, the standard UV lithography and wet chemical etching technique was used to fabricate microchannels on a K9 glass substrate. The fabrication process of microfluidic chip including vacuum evaporation, annealing, lithography, and BHF (HF-NH4F-H2O) wet etching were investigated. Through series experiments, we found that anneal was the critical factor for chip quality. As a representative example, a microfluidic channel with 20 m of depth, and 80 m of width was successfully prepared, and the channel surfaces are quite smooth. These results present a simple, low cost, flexible and easy way to fabricate glass-based microfluidic chips.

Highly sensitive visual detection of mutant DNA based on polymeric nanoparticles-participating amplification

RSC Advances ◽  
2016 ◽  
Vol 6 (116) ◽  
pp. 115238-115246 ◽  
Author(s):  
Yanjun Cui ◽  
Dequan Zhuang ◽  
Tianwei Tan ◽  
Jing Yang
Keyword(s):  
Surface Area ◽  
Visual Detection ◽  
Polymeric Nanoparticles ◽  
Large Surface Area ◽  
Highly Sensitive ◽  
Amplification System

Taking advantage of the nanoparticles' large surface area and structural repeating characteristics, polymeric nanoparticles-participating polymerization-based amplification system was designed to enhance the sensitivity of detection.

scholarly journals High Performance GAA SNWT with a Triangular Cross Section: Simulation and Experiments

2018 ◽  
Vol 8 (9) ◽  
pp. 1553 ◽  
Author(s):  
Ming Li ◽  
Gong Chen ◽  
Ru Huang
Keyword(s):  
Cross Section ◽  
High Performance ◽  
Silicon Nanowire ◽  
Wet Etching ◽  
Excellent Performance ◽  
Cross Sectional ◽  
Triangular Cross Section ◽  
Tcad Simulation ◽  
Equivalent Distance ◽  
20 Nm

In this paper, we present a gate-all-around silicon nanowire transistor (GAA SNWT) with a triangular cross section by simulation and experiments. Through the TCAD simulation, it was found that with the same nanowire width, the triangular cross-sectional SNWT was superior to the circular or quadrate one in terms of the subthreshold swing, on/off ratio, and SCE immunity, which resulted from the smallest equivalent distance from the nanowire center to the surface in triangular SNWTs. Following this, we fabricated triangular cross-sectional GAA SNWTs with a nanowire width down to 20 nm by TMAH wet etching. This process featured its self-stopped etching behavior on a silicon (1 1 1) crystal plane, which made the triangular cross section smooth and controllable. The fabricated triangular SNWT showed an excellent performance with a large Ion/Ioff ratio (~107), low SS (85 mV/dec), and preferable DIBL (63 mV/V). Finally, the surface roughness mobility of the fabricated device at a low temperature was also extracted to confirm the benefit of a stable cross section.

scholarly journals Development of micropillar array electrodes for highly sensitive detection of biomarkers

RSC Advances ◽  
2020 ◽  
Vol 10 (67) ◽  
pp. 41110-41119
Author(s):  
Chaozhan Chen ◽  
Bin Ran ◽  
Zhenxing Wang ◽  
Hongli Zhao ◽  
Minbo Lan ◽  
...  
Keyword(s):  
Surface Modification ◽  
Surface Area ◽  
High Sensitivity ◽  
Sensitive Detection ◽  
Highly Sensitive ◽  
Detection Of Biomarkers ◽  
Highly Sensitive Detection ◽  
Micropillar Array

PDMS-based micropillar array electrodes with increased surface area and surface modification were developed to detect biomarkers with high sensitivity.

scholarly journals Trimodal Waveguide Demonstration and Its Implementation as a High Order Mode Interferometer for Sensing Application

Sensors ◽  
2019 ◽  
Vol 19 (12) ◽  
pp. 2821 ◽  
Author(s):  
Jhonattan C. Ramirez ◽  
Lucas H. Gabrielli ◽  
Laura M. Lechuga ◽  
Hugo E. Hernandez-Figueroa
Keyword(s):  
Free Spectral Range ◽  
Point Of Care ◽  
Low Cost ◽  
High Order Mode ◽  
Sio2 Substrate ◽  
Polymer Waveguide ◽  
Sensing Applications ◽  
Highly Sensitive ◽  
Different Types ◽  
Mode Order

This work implements and demonstrates an interferometric transducer based on a trimodal optical waveguide concept. The readout signal is generated from the interference between the fundamental and second-order modes propagating on a straight polymer waveguide. Intuitively, the higher the mode order, the larger the fraction of power (evanescent field) propagating outside the waveguide core, hence the higher the sensitivity that can be achieved when interfering against the strongly confined fundamental mode. The device is fabricated using the polymer SU-8 over a SiO2 substrate and shows a free spectral range of 20.2 nm and signal visibility of 5.7 dB, reaching a sensitivity to temperature variations of 0.0586 dB/ ∘ C. The results indicate that the proposed interferometer is a promising candidate for highly sensitive, compact and low-cost photonic transducer for implementation in different types of sensing applications, among these, point-of-care.

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