scholarly journals “Lving” and “probiotic” cosmetics: modern view and defenitions

2017 ◽  
Vol 11 (4) ◽  
Author(s):  
N. Tkachenko ◽  
O. Chagarovskyi ◽  
N. Dets ◽  
E. Sevastyanova ◽  
L. Lanzhenko
Keyword(s):  
Human Body ◽  
Skin Diseases ◽  
Effective Means ◽  
Allergic Inflammation ◽  
Skin Microbiome ◽  
Cosmetic Products ◽  
Skin Damage ◽  
Complex Signals ◽  
Definition Of ◽  
Specific Disorders

In the presented article, based on the detailed analysis of scientific sources and many years of own experience in production of the probiotic foods, the definition of “probiotics” in cosmetics, as well as the definition of “living” and “probiotic” cosmetics is proposed.The skin is a complex barrier organ that has a symbiotic relationship between microbial communities and host tissue via complex signals provided by the innate and the adaptive immune systems. It is constantly exposed to various endogenous and exogenous factors – physical, chemical, bacterial and fungal, as well as the effects of the hormonal disorders, which affect this balanced system potentially leading to inflammatory skin conditions comprising infections, allergies or autoimmune diseases. In opposition to the gut and stool microbiome, which has been studied and described for many years, investigations on the skin or scalp microbiome lasts only for last 10 years. Therefore, the screening of effective means of correcting and/or maintaining the human normoflora for the preservation of healthy skin microbiome today is an urgent task.It is well known that probiotics and prebiotics are helpful for specific disorders in the human body. Skeptics wonder: can the probiotics and prebiotics be scientifically applied in cosmetics? Different clinical studies indicated that they have special effects in cutaneous apparatus directly or indirectly, which can be considered from different aspects. Probiotic bacteriotherapy can have great potential in accelerating wound healing, in preventing and treating the skin diseases including eczema, atopic dermatitis, acne, allergic inflammation or skin hypersensitivity, UV-induced skin damage and cosmetics products. Therefore, some firms are already incorporating bacteria and/or their lysates into skin creams with the promise of «rebalancing» the community of bacteria that live in the human body and delivering healthier, more radiant-looking skin. However, such parameters as the type of probiotic, the form in which it is added to the formulation (living bacteria, lysates, etc.) and the recommended concentrations of these ingredients in cosmetic products that are safe and effective are still not defined. Due to currently widespread use of probiotic cosmetic products in the world beauty industry, the concept of "probiotic" in the cosmetic industry requires a clear definition.

CURRENT STATE OF TECHNOLOGY FOR OBTAINING EXTRACT FROM CORN GERM (ZEA MAYS GERMINIS)

2021 ◽  
pp. 79-83
Author(s):  
А.Б. ЯРМАГАМЕТОВА ◽  
М.Ж. КИЗАТОВА
Keyword(s):  
Zea Mays ◽  
Chemical Composition ◽  
Human Body ◽  
Corn Germ ◽  
Biologically Active ◽  
Cosmetic Products ◽  
Current State ◽  
Therapeutic Value ◽  
Definition Of ◽  
Active Substances

В данной статье расматривается получение экстракта из зародыша кукурузы. Дается определение зародыша кукурузы (Zea mays germinis) и его значимость, как компонента, богатого биологически активными веществами, которые имеют терапевтическое значение для организма человека. Устанавлено, что получение экстракта из кукурузного зародыша для приготовления лекарственных и кометических средств является более выгодным процессом и имеет ценность благодаря своему богатому химическому составу и численности БАВ. This article discusses the preparation of an extract from the corn germ. The definition of the corn germ and its significance as a component rich in biologically active substances that have therapeutic value for the human body is given. It has been established that obtaining an extract from the corn germ for the preparation of medicinal and cosmetic products is a more profitable process and has value due to its rich chemical composition and the number of BAS.

scholarly journals Potential of Skin Microbiome, Pro- and/or Pre-Biotics to Affect Local Cutaneous Responses to UV Exposure

Nutrients ◽  
2020 ◽  
Vol 12 (6) ◽  
pp. 1795
Author(s):  
VijayKumar Patra ◽  
Irène Gallais Sérézal ◽  
Peter Wolf
Keyword(s):  
Immune Modulation ◽  
Skin Diseases ◽  
Treatment Strategies ◽  
Therapeutic Effects ◽  
Skin Microbiome ◽  
Skin Damage ◽  
Inflammatory Skin Diseases ◽  
Polymorphic Light Eruption ◽  
Skin Response ◽  
Novel Treatment Strategies

The human skin hosts innumerable microorganisms and maintains homeostasis with the local immune system despite the challenges offered by environmental factors such as ultraviolet radiation (UVR). UVR causes cutaneous alterations such as acute (i.e., sunburn) and chronic inflammation, tanning, photoaging, skin cancer, and immune modulation. Phototherapy on the other hand is widely used to treat inflammatory skin diseases such as psoriasis, atopic dermatitis, polymorphic light eruption and graft-versus-host disease (GvHD), as well as neoplastic skin diseases such as cutaneous T cell lymphoma, among others. Previous work has addressed the use of pro- and pre-biotics to protect against UVR through anti-oxidative, anti-inflammatory, anti-aging, anti-carcinogenic and/or pro-and contra-melanogenic properties. Herein, we discuss and share perspectives of the potential benefits of novel treatment strategies using microbes and pro- and pre-biotics as modulators of the skin response to UVR, and how they could act both for protection against UVR-induced skin damage and as enhancers of the UVR-driven therapeutic effects on the skin.

scholarly journals Tanggung Jawab Hukum Pelaku Usaha Atas Peredaran Kosmetika Yang Diduga Mengandung Bahan Berbahaya Dan Tidak Memenuhi Standart Mutu Menurut Undang-Undang Nomor 8 Tahun 1999 tentang Perlindungan Kosumen (Studi Kasus Produk Kosmetika Hasil Rilis BPOM)

2019 ◽  
Vol 2 (2) ◽  
pp. 1450
Author(s):  
Dede Afandi Hamid ◽  
Ermanto Fahamsyah
Keyword(s):  
Human Body ◽  
Cosmetic Products ◽  
High Quality ◽  
Ministry Of Health ◽  
The Public ◽  
Legal Instrument ◽  
Definition Of

UUPK has explained that the legal instrument which protect the consumers was not intended to shut off the business of businessmen. But actually it becomes a Healthy Business Season and becomes a strong company in facing up the rivalry through the supply of high quality goods and services.Human was perfectly created by God. The willingness in  every human  to appear more attractive and perfect has become a trend, not only for women but also men as well as teenagers that we are  called “millennials” becomes a proper things.The definition of cosmetic under The Regulation of Ministry of Health 1175/2010 about the cosmetic production permit is the ingredients and preparations to be used on the outside of the human body (epidermis, hair, nails, mouth, and outer genital organs). Head of BPOM appeals to the public to be smart consumers in choosing cosmetics. During 2018, BPOM has foreclosed illegal cosmetics worth 106.9 billion rupiah. In that Case, BPOM asked to the public to avoid some cosmetic products.

scholarly journals A Spectral-Based Approach for BCG Signal Content Classification

Sensors ◽  
2021 ◽  
Vol 21 (3) ◽  
pp. 1020
Author(s):  
Mohamed Chiheb Ben Nasr ◽  
Sofia Ben Jebara ◽  
Samuel Otis ◽  
Bessam Abdulrazak ◽  
Neila Mezghani
Keyword(s):  
Human Body ◽  
Supervised Classification ◽  
Unsupervised Classification ◽  
Gaussian Mixture ◽  
K Nearest Neighbors ◽  
Content Classification ◽  
Extraction Step ◽  
Vital Sign Measurement ◽  
Definition Of ◽  
Spectral Flatness Measure

This paper has two objectives: the first is to generate two binary flags to indicate useful frames permitting the measurement of cardiac and respiratory rates from Ballistocardiogram (BCG) signals—in fact, human body activities during measurements can disturb the BCG signal content, leading to difficulties in vital sign measurement; the second objective is to achieve refined BCG signal segmentation according to these activities. The proposed framework makes use of two approaches: an unsupervised classification based on the Gaussian Mixture Model (GMM) and a supervised classification based on K-Nearest Neighbors (KNN). Both of these approaches consider two spectral features, namely the Spectral Flatness Measure (SFM) and Spectral Centroid (SC), determined during the feature extraction step. Unsupervised classification is used to explore the content of the BCG signals, justifying the existence of different classes and permitting the definition of useful hyper-parameters for effective segmentation. In contrast, the considered supervised classification approach aims to determine if the BCG signal content allows the measurement of the heart rate (HR) and the respiratory rate (RR) or not. Furthermore, two levels of supervised classification are used to classify human-body activities into many realistic classes from the BCG signal (e.g., coughing, holding breath, air expiration, movement, et al.). The first one considers frame-by-frame classification, while the second one, aiming to boost the segmentation performance, transforms the frame-by-frame SFM and SC features into temporal series which track the temporal variation of the measures of the BCG signal. The proposed approach constitutes a novelty in this field and represents a powerful method to segment BCG signals according to human body activities, resulting in an accuracy of 94.6%.

scholarly journals Neurocosmetics in Skincare—The Fascinating World of Skin–Brain Connection: A Review to Explore Ingredients, Commercial Products for Skin Aging, and Cosmetic Regulation

Cosmetics ◽  
2021 ◽  
Vol 8 (3) ◽  
pp. 66
Author(s):  
Vito Rizzi ◽  
Jennifer Gubitosa ◽  
Paola Fini ◽  
Pinalysa Cosma
Keyword(s):  
Nervous System ◽  
Inflammatory Responses ◽  
Skin Aging ◽  
Cosmetic Products ◽  
Sensitive Skin ◽  
Functional Ingredients ◽  
Major Application ◽  
Regulatory Aspect ◽  
Brain Connection ◽  
Definition Of

The “modern” cosmetology industry is focusing on research devoted to discovering novel neurocosmetic functional ingredients that could improve the interactions between the skin and the nervous system. Many cosmetic companies have started to formulate neurocosmetic products that exhibit their activity on the cutaneous nervous system by affecting the skin’s neuromediators through different mechanisms of action. This review aims to clarify the definition of neurocosmetics, and to describe the features of some functional ingredients and products available on the market, with a look at the regulatory aspect. The attention is devoted to neurocosmetic ingredients for combating skin stress, explaining the stress pathways, which are also correlated with skin aging. “Neuro-relaxing” anti-aging ingredients derived from plant extracts and neurocosmetic strategies to combat inflammatory responses related to skin stress are presented. Afterwards, the molecular basis of sensitive skin and the suitable neurocosmetic ingredients to improve this problem are discussed. With the aim of presenting the major application of Botox-like ingredients as the first neurocosmetics on the market, skin aging is also introduced, and its theory is presented. To confirm the efficacy of the cosmetic products on the market, the concept of cosmetic claims is discussed.

scholarly journals Determination of Ten Corticosteroids in Illegal Cosmetic Products by a Simple, Rapid, and High-Performance LC-MS/MS Method

2017 ◽  
Vol 2017 ◽  
pp. 1-12 ◽  
Author(s):  
Vita Giaccone ◽  
Giuseppe Polizzotto ◽  
Andrea Macaluso ◽  
Gaetano Cammilleri ◽  
Vincenzo Ferrantelli
Keyword(s):  
High Performance ◽  
Skin Diseases ◽  
Gradient Elution ◽  
Reversed Phase ◽  
Cosmetic Products ◽  
Chromatography Method ◽  
Esi Ms ◽  
Negative Ionization Mode ◽  
Negative Ionization

The aim of our present work was the development of a rapid high-performance liquid chromatography method with electrospray ionization and tandem mass spectrometry detection (LC-ESI-MS/MS) for the determination of several corticosteroids in cosmetic products. Corticosteroids are suspected to be illegally added in cosmetic preparations in order to enhance the curative effect against some skin diseases. Sample preparation step consists in a single extraction with acetonitrile followed by centrifugation and filtration. The compounds were separated by reversed-phase chromatography with water and acetonitrile (both with 0.1% formic acid) gradient elution and detected by ESI-MS positive and negative ionization mode. The method was validated at the validation level of 0.1 mg kg−1. Linearity was studied in the 5–250 μg L−1 range and linear coefficients (r2) were all over 0.99. The accuracy and precision of the method were satisfactory. The LOD ranged from 0.085 to 0.109 mg kg−1 and the LOQ from 0.102 to 0.121 mg kg−1. Mean recoveries for all the analytes were within the range 91.9–99.2%. The developed method is sensitive and useful for detection, quantification, and confirmation of these corticosteroids in cosmetic preparations and can be applied in the analysis of the suspected samples under investigation.

Bodily Dasein and Chinese Script Components

2017 ◽  
Vol 2017 (2) ◽  
Author(s):  
Kwan Tze-wan
Keyword(s):  
Human Body ◽  
The Body ◽  
Chinese Script ◽  
Chinese Characters ◽  
Body Parts ◽  
Constitutive Principle ◽  
New Perspective ◽  
Social Environmental ◽  
The One ◽  
Definition Of

AbstractIn the Shuowen, one of the earliest comprehensive character dictionaries of ancient China, when discussing where the Chinese characters derive their structural components, Xu Shen proposed the dual constitutive principle of “adopting proximally from the human body, and distally from things around.” This dual emphasis of “body” and “things around” corresponds largely to the phenomenological issues of body or corporeality on the one hand, and lifeworld on the other. If we borrow Heidegger’s definition of Dasein as Being-in-the world, we can easily arrive at a reformulation of Xu Shen’s constitutive principle of the Chinese script as one that concerns “bodily Dasein.” By looking into various examples of script tokens we can further elaborate on how the Chinese make use not only of the body in general but various body parts, and how they differentiate their life world into material nature, living things, and a multifaceted world of equipment in forming a core basis of Chinese characters/components, upon which further symbolic manipulation such as “indication”, “phonetic borrowing”, semantic combination, and “annotative derivation”, etc. can be based. Finally, examples will be cited to show how in the Chinese scripts the human body (and its parts) might interact with other’s bodies (and their parts) or with “things around” (whether nature, living creatures, or artifacts) in various ways to cover the social, environmental, ritual, technical, economical, and even intellectual aspects of human experience. Bodily Dasein, so to speak, provides us with a new perspective of understanding and appreciating the entire scope of the Chinese script.

scholarly journals BIOLOGICAL AGE AS A METHOD FOR ESTIMATING HEALTH LEVEL UNDER ENVIRONMENTAL RISKS (LITERATURE REVIEW)

2019 ◽  
Vol 98 (7) ◽  
pp. 761-765 ◽  
Author(s):  
N. I. Prokhorov ◽  
V. I. Dontsov ◽  
Vyacheslav N. Krutko ◽  
T. M. Khodykina
Keyword(s):  
Human Body ◽  
Quantitative Assessment ◽  
Modern Human ◽  
The Body ◽  
Biological Age ◽  
Whole Body ◽  
New Methods ◽  
Biomarkers Of Aging ◽  
Age Related ◽  
Definition Of

The widespread formation of unfavorable environmental, the swiftness of modern life with large information and psycho-emotional loads and extremely natural and climatic cataclysms, as well as harmful addictions and wrong way of life of modern human, lead to the development of stress and disruption of the mechanisms of adaptation of the human body and its accelerated wear. This stimulates the development of research on the creation of new methods of integrated assessment of health and quantitative assessment of the aging processes of the body systems and the whole body, as well as the possibilities of new methods of risk assessment of climatic and environmentally related pathological and age-related diseases. The aim of the work was to consider the methodology of quantitative assessment of individual health and the rate of aging of the human body on the basis of the system index of Biological age (BA); description of its essence and structure, requirements for tests - biomarkers of aging used as the index of BA, definition of possibilities and scope of application of the BA method in modern practice of Biomedicine. The use of modern methods of scientific analysis - a systematic approach to the analysis of the processes of human aging and determine its quantitative side - the value of BA, allows a reasonable approach to the choice of the number of BM, to take into account their information content and precision, and the cost of diagnostics and availability for different users, to take into account the specific objectives of the researcher. The use of the index-partial BA allows individual approaching the choice of biomarkers and create personalized panels for the definition of BA programs for the prevention of aging in personalized preventive medicine. The complexity of the content and calculation of indices of BA requires automation and the use of methods of modern computer science and computer calculations and programs. For this purpose, we have created special computer software for diagnosing aging by calculating the BA indices with the possibility of choosing BM and automatic calculation of indicators and conclusions.

DEVELOPMENT OF MODELS FOR DIAGNOSTIC DIABETES BASED ON FUZZY LOGIC METODS

2021 ◽  
pp. 90-95
Author(s):  
Евгений Николаевич Коровин ◽  
Екатерина Ивановна Новикова ◽  
Олег Валерьевич Родионов
Keyword(s):  
Mathematical Modeling ◽  
Decision Making ◽  
Information Technology ◽  
Fuzzy Logic ◽  
Human Body ◽  
Patient Information ◽  
Decision Making Process ◽  
Speed Up ◽  
Definition Of

В статье рассматриваются разработки методов интеллектуальной поддержки процесса диагностики сахарного диабета, а также определение его типа. В последние годы количество людей, страдающих данным заболеванием, неуклонно растет, а без своевременной диагностики эта патология может нанести огромный вред организму человека. Сахарный диабет 1 типа опасен тем, что в основном возникает у людей молодого возраста. Оперативное обнаружение диабета, а также определение его типа, поможет не только избежать возможных осложнений, но и в некоторых случаях предотвратить смерть пациента. Информационные технологии все чаще используются в различных сферах деятельности для разработки новых или совершенствования существующих методов обработки данных, особенно это можно заметить в сфере медицины. В настоящее время врач самостоятельно ставит диагноз, основываясь на результатах различных анализов, однако, для ускорения процесса принятия решения, можно воспользоваться методами математического моделирования, а именно: моделями диагностики диабета на основе нечеткой логики. Для наибольшего удобства данный способ распознавания заболевания впоследствии можно реализовать в информационно-программное обеспечение, которое сможет еще больше увеличить эффективность и скорость распознавания патологии The article discusses the issues of the incidence of diabetes in the population, in particular, the definition of its type. In recent years, the number of people suffering from this disease has been steadily growing, and without timely diagnosis, this pathology can cause enormous harm to the human body. Prompt detection of diabetes, as well as determination of its type, will help not only avoid possible complications, but also in some cases prevent the death of the patient. Information technology is increasingly being used in various fields of activity to develop new or improve existing methods of data processing, especially in the field of medicine. Currently, the doctor independently makes a diagnosis based on the results of various analyzes, however, to speed up the decision-making process, you can use the methods of mathematical modeling, namely, models of diabetes diagnostics based on fuzzy logic. For the greatest convenience, this method of disease recognition can subsequently be implemented in information software, which can further increase the efficiency and speed of pathology recognition

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