scholarly journals Neurological complications in dengue infection: a review for clinical practice

2013 ◽  
Vol 71 (9B) ◽  
pp. 667-671 ◽  
Author(s):  
Marzia Puccioni-Sohler ◽  
Carolina Rosadas ◽  
Mauro Jorge Cabral-Castro

Dengue is an important global public health problem. The World Health Organization estimates that 2/5 of entire world population are in risk of dengue infection. Almost 50 millions cases occur annually, with at least 20 thousand deaths. The etiological agent of this acute febrile disease is a single-strand positive-sense RNA virus of Flavivirus genus. It is an arboviral disease transmitted by Aedes sp. mosquitoes (Aedes aegypti and A. albopictus). Most infected individuals present asymptomatic infection, but some may develop clinical signs. Therefore, a wide spectrum of illness can be observed, ranging from unapparent, mild disease, called dengue fever, to a severe and occasionally fatal dengue hemorrhagic fever/dengue shock syndrome. Currently, neurological manifestations related to dengue infections are increasingly been observed and appears as a challenge for medical practice. In this study the neurological complications of dengue infection will be reviewed, focusing a better understanding of the disease for the clinical practice.

2018 ◽  
Vol 17 (1) ◽  
pp. 21-29
Author(s):  
Peter J Olagunju ◽  
Olukemi O Odukoya ◽  
Andrew T Olagunju ◽  
Mobolanle R Balogun

Background: Tuberculosis [TB] remains a major global public health problem, and particularly in resource-restricted settings with disproportionately high burden. This study is aimed at assessing quality of life [QoL] and the roles of HIV co-infection along with socio-demographic factors on QoL among subjects with TB.Methodology: This is a multi-center cross-sectional study among 440 participants recruited by multi-stage sampling technique across 40 Directly Observed Treatment Short-course [DOTS] centres. Interviews were done using designed questionnaire to collect information on socio-demographic and clinical details of respondents. Subsequently, the World Health Organization Quality of Life-BREF [WHOQOL-BREF] questionnaire was used to evaluate QoL.Results: Most (61.1%) of the participants was aged between 21 and 40 years, 61.6% were married and 74.5% had a paid job. Majority of the subjects reported fair QoL across all domains. Employment status and monthly income were significantly associated with participants overall QoL and their satisfaction with health (p<0.05). Also, age, gender, marital status, ethnicity and educational status were significantly associated with the social domain of QoL. The HIV co-infection was found to be significantly associated with the physical aspect of their QoL (p<0.05).Conclusion: Optimal treatment of HIV co-infection and incorporation of psychosocial medicine into TB management are indicated for improved QoL. Similarly, routine assessment of QoL is desirable.Bangladesh Journal of Medical Science Vol.17(1) 2018 p.21-29


2019 ◽  
Vol 9 (2) ◽  
pp. 24-28
Author(s):  
Alisha Dhungana ◽  
Kalpana Jnawali

Introduction: Infertility is the global public health problem with adverse social and economic consequences. World Health Organization states that infertility affects 1 in every 10 couples worldwide. This study was carried out with an objective to find out the level of knowledge and belief regarding infertility among undergraduate students. Methods: This was a cross-sectional and quantitative study, carried out among 420 undergraduate students of 7 selected colleges of Pokhara Metropolitan city from July to September 2019. Study populations were selected through simple random sampling method. Data collection was carried out using self-administered questionnaire. Results: Study revealed that 51.9% students had good level of knowledge with the female students having greater knowledge (57%) than male (48%). The study found that students’ knowledge score related to infertility was significantly associated with gender (p<0.05) and parental advices (p<0.05). Conclusions: More than half of the participants had good level of knowledge. Female students were more knowledgeable than male students. Less than half of the participants had ever attended on sexual and reproductive training programs.


2021 ◽  
Vol 9 (9) ◽  
pp. 2144-2150
Author(s):  
Shivam Kumar Nigam ◽  
Rita Singh ◽  
Sanjay Srivastava

Pandu Roga is one of the diseases mentioned in Ayurveda characterized by the changes in the skin colour to white (Shweta), yellowish (Peeta), greenish (Harita) etc. which is one of the “Varnopalakshita Roga" i.e., a disease characterized by the change in the colour. The clinical condition of Pandu in Ayurveda can be co-related with Anaemia described in Modern Medical Science, due to the resemblance in the clinical signs and symptoms. In Modern Medicine, Pandu is a pale appearance which may be due to the decreased blood supply to the skin or de- creased visibility of oxyhemoglobin. Anaemia is a major global public health problem and the most prevalent nu- tritional deficiency disorder in the world. This article presents the Ayurvedic concept of Pandu Roga (Anaemia). Keywords: Pandu, Vyadhi, Srotas, Anaemia, Pallor,


2018 ◽  
Vol 4 (1) ◽  
pp. 21 ◽  
Author(s):  
Jean-Pierre Zellweger ◽  

Tuberculosis (TB) is a major global public health problem and is the leading cause of death linked to a single pathogen, ranking above human immunodeficiency virus (HIV).1 Clinically, TB has been categorised as active disease (patients who are generally symptomatic and may be infectious if pulmonary involvement is present) and latent infection (asymptomatic and not infectious, but at variable risk for progression to active TB disease). It is increasingly being recognised that latent TB infection (LTBI) reflects diverse responses to infection with Mycobacterium tuberculosis and may lead to heterogeneous clinical outcomes. In an expert interview, Jean-Pierre Zellweger discusses the latest World Health Organisation (WHO) guidelines on the management of LTBI.


Author(s):  
Rosyadi Aziz Rahmat ◽  
Devy Lestari Nurul Aulia

Background : According to the World Health Organization (WHO) HIV continues to be a global public health problem, claiming more than 70 million people are infected with the HIV virus and around 35 million people have died. In 2015, approximately 1.1 (940 000-1300000) million people have died due to being infected with the HIV virus. There were an estimated 36.7 (34.0-39.8) million people living with HIV at the end of 2016. Globally, Sub-Saharan Africa is the most affected region, with nearly 1 in 25 adults living with HIV. (WHO 2016). The purpose of this study was to determine the compliance of commercial sex workers on using condoms in the localization of Teluk Bakau, Batam City. Method : This study used a descriptive research design. The location of this research was carried out in the localization of Teluk Bakau, Batam City. The population in this study were all commercial sex workers (CSWs) in the Teluk Bakau brothels with a total of 95 people. The sample is an object under study and is considered to represent the entire population, here the writer uses a purposive technique, namely by means of sampling based on criteria. The measuring instrument in this study using a questionnaire. This analysis was carried out on each variable. These results are in the form of distribution and percentage of each variable. Data analysis was carried out in a univariate manner by looking at the results of the frequency calculation and the presentation of the results which could later be used as benchmarks for discussion and conclusions. Results and conclusions : It can be seen that the compliance of CSWs using condoms in the Bakau Bay brothel, Batam City is the majority of the majority behave obediently as many as 46 respondents (93.9%)


2019 ◽  
Vol 48 (1) ◽  
pp. 32-39
Author(s):  
Deidra C. Crews ◽  
Aminu K. Bello ◽  
Gamal Saadi ◽  

Kidney disease is a global public health problem, affecting over 750 million persons worldwide. The burden of kidney disease varies substantially across the world. In many settings, rates of kidney disease and the provision of its care are defined by socioeconomic, cultural, and political factors leading to significant disparities. World Kidney Day 2019 offers an opportunity to raise awareness of kidney disease and highlight disparities in its burden and current state of global capacity for prevention and management. Here, we highlight the need for strengthening basic infrastructure for kidney care services for early detection and management of acute kidney injury and chronic kidney disease across all countries and advocate for more pragmatic approaches to providing renal replacement therapies. Achieving universal health coverage worldwide by 2030 is a World Health Organization Sustainable Development Goal. While universal health coverage may not include all elements of kidney care in all countries, understanding what is locally feasible and important with a focus on reducing the burden and consequences of kidney disease would be an important step towards achieving kidney health equity.


2016 ◽  
Vol 04 (02) ◽  
pp. 067-070 ◽  
Author(s):  
Ranabir Salam

AbstractNoncommunicable diseases (NCDs) are responsible for 68% of all deaths in 2012. Eighty-two percent of these “premature” deaths occurred in low- and middle-income countries. Most of the NCD deaths are caused by cardiovascular diseases, cancer, diabetes, chronic respiratory diseases, mental health, road traffic accidents, and violence. The World Health Organization, several governments, and nongovernmental organizations have taken up numerous programs to curb the menace of NCDs. However, the present programs do not include some common chronic medical conditions which also lead to considerable morbidity and mortality. The present review highlights three important chronic disorders: chronic kidney disease (CKD), liver disease (cirrhosis and nonalcoholic fatty liver), and thyroid diseases. CKD is an internationally recognized public health problem affecting 5–10% of the world population. CKD resulted in 956,000 deaths in 2013 and proposes them to be included in the world wide accepted definition of NCD. Cirrhosis and chronic liver disease were the tenth leading cause of death for men and the twelfth for women in the United States in 2001. Moreover, 4–10% of the global population have thyroid dysfunction. This mini-review proposes to expand the definition of NCD to include these three major illnesses.


2010 ◽  
Vol 43 (4) ◽  
pp. 355-358 ◽  
Author(s):  
Luciano Pamplona de Góes Cavalcanti ◽  
Ivo Castelo Branco Coelho ◽  
Dina Cortez Lima Feitosa Vilar ◽  
Susana Glória Silveira Holanda ◽  
Kiliana Nogueira Farias da Escóssia ◽  
...  

INTRODUCTION: The dengue hemorrhagic dengue (DHF) remains an important public health problem in Brazil. The objective of this study was to analyze the epidemiological characteristics of DHF cases during the 2003 epidemic in Ceará. METHODS: Suspected DHF cases with onset of symptoms between January and December 2003 were investigated. RESULTS: 37,964 classic dengue cases and 291 DHF cases were reported. Among the cases discarded, 75.5% were serologically positive but did not meet the criteria recommended by the World Health Organization (WHO). The DHF patients' median age was 30 years (2 - 88). Among the hemorrhagic manifestations, petechiae were the most (32.6%) frequent. Cases of gastrointestinal bleeding, ascites, pericardial pleural effusion, hepatomegaly, hypotension and shock showed higher risk of progression to death (p <0.05). CONCLUSIONS: The introduction of a new serotype (DENV-3) in Ceará, which encountered a susceptible population and high vector density, may have been the primary agent responsible for the magnitude of the epidemic. Timely and appropriate medical care, along with an organized care structure are essential for reducing its lethality.


Electronics ◽  
2020 ◽  
Vol 9 (5) ◽  
pp. 780 ◽  
Author(s):  
Giovanni Dimauro ◽  
Serena De Ruvo ◽  
Federica Di Terlizzi ◽  
Angelo Ruggieri ◽  
Vincenzo Volpe ◽  
...  

Anemia is a global public health problem with major consequences for human health. About a quarter of the world population shows a hemoglobin concentration that is below the recommended thresholds. Non-invasive methods for monitoring and identifying potential risk of anemia and smartphone-based devices to perform this task are promising in addressing this pathology. We have considered some well-known studies carried out on this topic since the main purpose of this work was not to produce a review. The first group of papers describes the approaches for the clinical evaluation of anemia focused on different human exposed tissues, while we used a second group to overview some technologies, basic methods, and principles of operation of some devices and highlight some technical problems. Results extracted from the second group of papers examined were aggregated in two comparison tables. A growing interest in this topic is demonstrated by the increasing number of papers published recently. We believe we have identified several critical issues in the published studies, including those published by us. Just as an example, in many papers the dataset used is not described. With this paper we wish to open a discussion on these issues. Few papers have been sufficient to highlight differences in the experimental conditions and this makes the comparison of the results difficult. Differences are also found in the identification of the regions of interest in the tissue, descriptions of the datasets, and other boundary conditions. These critical issues are discussed together with open problems and common mistakes that probably we are making. We propose the definition of a road-map and a common agenda for research on this topic. In this sense, we want to highlight here some issues that seem worthy of common discussion and the subject of synergistic agreements. This paper, and in particular, the discussion could be the starting point for an open debate about the dissemination of our experiments and pave the way for further updates and improvements of what we have outlined.


2019 ◽  
Vol 6 (Supplement_2) ◽  
pp. S885-S885 ◽  
Author(s):  
Jehan Budak ◽  
Eneyi E Kpokiri ◽  
Emily Abdoler ◽  
Joseph Tucker ◽  
Brian Schwartz ◽  
...  

Abstract Background Antimicrobial resistance (AMR) is a global public health problem, but the learning needs of the medical profession on this topic are not well understood. The World Health Organization has called for better educational resources on AMR. Thus, we aimed to identify AMR learning objectives for physicians and medical trainees. Methods We designed a modified, two-round Delphi process to build consensus around these objectives, recruiting attendees at a one-day, multidisciplinary, international AMR symposium. Through review of the literature and discussion with experts in AMR, we generated an initial list of 17 objectives. We asked participants to rate the importance of including each objective in an AMR curriculum for physicians on a 5-point Likert scale, which ranged from “do not include” (1) to “very important to include” (5). Consensus for inclusion was predefined as ≥ 80% of participants rating the objective ≥ 4. Results The first round was completed by 30 participants, and the second by 21. Nobody declined to participate, but several people had to leave between rounds. Participants included physicians, researchers, graduate students, and a pharmacist, foundation manager, patient advocate, leader of an international financial institution, health administrator, and biomedical scientist. After the first round, 16 objectives met the consensus criteria, and participants suggested five additional topics. After the second round, 12 objectives met the consensus criteria (see Table 1). Objectives related to treatment of AMR most frequently met consensus criteria. Specific objectives with the highest consensus ratings were related to identifying infections not requiring antibiotics and recognizing the importance of using the narrowest spectrum antibiotic for the shortest period of time. Conclusion We successfully employed a modified, one-day Delphi process at an international, multidisciplinary AMR symposium to build consensus among experts and stakeholders regarding key learning objectives for AMR. This technique may be useful for guideline committees and other taskforces in the Infectious Diseases community. Our generated list may be useful for those developing AMR training materials for medical students and physicians. Disclosures All authors: No reported disclosures.


Sign in / Sign up

Export Citation Format

Share Document