scholarly journals Effect of dietary antibacterial peptide and zinc-methionine on performance and serum biochemical parameters in piglets

2011 ◽  
Vol 56 (No. 1) ◽  
pp. 30-36 ◽  
Author(s):  
J.H. Wang ◽  
C.C. Wu ◽  
J. Feng
Keyword(s):  
Biochemical Parameters ◽  
Average Daily Gain ◽  
Density Lipoprotein ◽  
Antibacterial Peptide ◽  
Control Group ◽  
Serum Biochemical Parameters ◽  
Peptide Group ◽  
Zinc Methionine ◽  
Serum Biochemical ◽  
Daily Gain

The objective of this study was to evaluate the effect of dietary supplementation of antibacterial peptide and zinc methionine on performance and some serum biochemical parameters of weaned piglets. Rongchang male piglets (28 days of age, initial weight 8.4 &plusmn; 0.65 kg) were used. All piglets were randomly allotted to four diets including the control group, the antibacterial peptide (AP) group containing 10 mg antibacterial peptide/kg diet, the zinc methionine (Zn-Met) group with 1 200 zinc methionine/kg diet (equal to 200 mg Zn<sup>2+</sup>/kg diet), the zinc methionine/antibacterial peptide (Zn/AP) group containing 10 mg antibacterial peptide and 1 200 mg zinc methionine/kg diet, respectively, in a 4-week feeding experiment. Each of these groups consisted of six replications with 8 pigs per replication. Average daily gain (ADG) and average daily feed intake (ADFI) both improved in the antibacterial peptide group (P &lt; 0.05, P &lt; 0.05), zinc methionine group (P &lt; 0.05, P &lt; 0.05) and zinc methionine/antibacterial peptide group (P &lt; 0.01, P &lt; 0.05), as compared with the control. Dietary zinc methionine also significantly reduced the diarrhoea ratio of piglets (P &lt; 0.05). The serum immunoglobulin G (IgG) and superoxide dismutase (SOD) were increased (P &lt; 0.05) and total cholesterol (TC) decreased (P &lt; 0.05) in the antibacterial peptide group and zinc-methionine group, the high density lipoprotein (HDL) increased (P &lt; 0.05) in the zinc methionine group, as compared with the control. The results indicated that antibacterial peptide and zinc methionine were effective in improving growth performance, enhancing immune function, blood vessel function and antioxidant enzyme activity of piglets.

scholarly journals The effect of camel milk curd masses on rats blood serum biochemical parameters: Preliminary study

PLoS ONE ◽  
2021 ◽  
Vol 16 (9) ◽  
pp. e0256661
Author(s):  
Fatima Dikhanbayeva ◽  
Elmira Zhaxybayeva ◽  
Zhuldyz Smailova ◽  
Arman Issimov ◽  
Zhechko Dimitrov ◽  
...  
Keyword(s):  
Blood Serum ◽  
Total Protein ◽  
Biochemical Parameters ◽  
Camel Milk ◽  
Control Group ◽  
Serum Biochemical Parameters ◽  
Group V ◽  
Group I ◽  
Serum Biochemical ◽  
Group Ii

This study aimed to assess potential feeding effect of camel milk curd mass and its mixes to experimental rat’s blood serum biochemical parameters, enzymatic activity and the peptide toxicity. Fifty healthy male Sprague-Dawley rats were divided into five groups (n = 10 each). Each group was fed with camel milk pure curd mass and its mixes for 16 days. At the end of the experiment, rats were sacrificed to collect the samples from the blood serum. Blood serum biochemical parameters total protein, cholesterol, glucose, albumin, triglycerides; the enzymatic activities of alanine aminotransferase, aspartate aminotransferase, alkaline phosphatase were determined on the A25 automatic analyser, and peptide toxicity analysed by the reference method. The statistical data have shown no significant differences in body weight gain in all groups. Total protein decreased in group II, IV, and V; however, it increased in group III compared to the control group. Cholesterol grew up in group II and it slightly increased in group V, dropped in groups III and IV compared to group I result. Glucose increased in groups II, III, IV compared to group I; still, group V results show a slight decrease. Albumin decreased in group IV, yet in group V it increased than the group I result. Simultaneously, groups II and III results were changed with less percentage. Triglyceride grew up in groups II, V, and it dropped significantly in groups III, IV compared to the control group. De Ritis ratio of enzymes in groups II, III, and IV fluctuated between 1.31 and 0.98 IU/L; however, group V demonstrated significant data versus group I. Diets peptide toxicity in all groups was lower than control group data. The experimental results indicated that curd mass from camel milk could be used as a pure or with additives and it did not discover the observed side effects.

scholarly journals Effects of feeding varying levels of fufu sieviate meal based diets with Panicum maximum basal on the blood characteristics of West African dwarf goats

2018 ◽  
Vol 6 (1) ◽  
Author(s):  
Peter-Damian Chukwunomso Jiwuba ◽  
Ekeno Michael Assam ◽  
Eka Christian Inyang
Keyword(s):  
Biochemical Parameters ◽  
West African ◽  
Control Group ◽  
Panicum Maximum ◽  
Serum Biochemical Parameters ◽  
West African Dwarf ◽  
West African Dwarf Goats ◽  
Serum Biochemical ◽  
Biochemical Indices ◽  
Dwarf Goats

The effects of fufu sieviate meal based diets at 0%, 20%, 40% and 60% levels using Panicum maximum as the basal on the haematological and serum biochemical parameters of West African dwarf (WAD) goats were studied for 87 days. Thirty six blood samples were collected from the WAD goats and their haematological and serum biochemical indices were determined using Beckman Coulter Ac-T10 Laboratory Haematology Blood Analyzer and Bayer DCA 2000+ HbA1c analyzer, respectively using a completely randomized design. Packed cell volume (PCV) was better (p<0.05) at T1 than the other treatments. Red Blood Cell (RBC) and mean corpuscular haemoglobin (MCH) were numerically improved at T2, T3 and T4 than in the control group while lymphocyte increased significantly (P<0.05) with increasing levels of the test ingredient. Results on serum biochemical indices showed that serum urea, creatinine, glucose and ALP differed significantly (P<0.05) and tended to be higher in the treatment (T2, T3 and T4)groups than the control group. The study therefore revealed that inclusion of fufu sieviate in the diets of West African Dwarf goats had no deleterious effects on the haematological and serum biochemical parameters of WAD goats and could be included up to 60% in goat diets.

scholarly journals Effect of a hydroethanol 70% extract from trunk bark of Terminalia superba Engl. and diels (combretaceae) on some serum biochemical parameters in rats

2017 ◽  
Vol 6 (6) ◽  
pp. 1242
Author(s):  
Goze N. Bernard ◽  
N’Dri N. Mathieu ◽  
Yapo A. Paul
Keyword(s):  
Biochemical Parameters ◽  
Direct Bilirubin ◽  
Female Rats ◽  
Control Group ◽  
High Dose ◽  
Distilled Water ◽  
Serum Biochemical Parameters ◽  
Group A ◽  
Serum Biochemical ◽  
Terminalia Superba

Background: In the framework of the valorization of traditional medicine, the biotolerance study of a hydroethanol 70% extract from trunk bark of Terminalia superba (HE 70%) Engl. and Diels (Combretaceae), a medicinal plant used for the treatment of gastric ulcer in Côte d'Ivoire was carried out by oral administration repeated for 28 days to three rat groups at doses 250, 500 and 750 mg/kg per body weight (b.w.).Methods: Fifty rats were randomly divided in four groups of ten animals including three test groups and one control group. Each group included five male and five female rats. An additional satellite group of ten rats in group treated at high dose (750mg/kg b.w.) was included in order to observe reversibility, persistence or late appearance of toxic effects at least 14 days after stopping the treatment. Three doses were prepared (250; 500 and 750mg/kg b.w.) corresponding to extract concentrations (12.5; 25 and 37.5mg/ml) were given to groups B, C and D respectively. Group A, served as control group, received distilled water at 2ml/kg b.w. Groups B, C and D, received orally HE 70% extract at 250, 500 and 750mg/kg respectively. Serum AST, ALT, total and direct bilirubin, total, HDL, LDL-cholesterols, triglycerides, urea and creatinine were estimated using standard methods.Results: The blood withdrawal analysis done previously (day 0) and at the end of every week on dry tubes revealed that at all weeks and for all doses, this extract do not affect serum values of total and direct bilirubin, creatinine, total, HDL, LDL-cholesterols and triglycerides. Oppositely, this extract reduced significantly (P<0.05) ALT serum rate at the 14th and 28th day at 750mg/kg b.w. respectively. In addition, at the 28th day, AST rate decreased significantly (P<0.05) at 750mg/kg b.w. Glycemia showed a significant (P <0.05) reduction at the 28th day at doses 500 and 750 mg/kg b.w. In contrast, urea increased significantly (P<0.05) at the 28th day at 500mg/kg b.w.Conclusions: This study showed that the use of a hydroethanol 70% extract from trunk bark of T. superba would be hepatoprotective, nontoxic for kidneys, liver and hypoglycemic at the studied doses.

scholarly journals Effects of Different Dietary Protein Levels on the Growth Performance, Serum Biochemical Parameters, Fecal Nitrogen, and Carcass Traits of Huanjiang Mini-Pigs

2021 ◽  
Vol 8 ◽  
Author(s):  
Xichen Zhao ◽  
Yating Liu ◽  
Hao Ding ◽  
Pan Huang ◽  
Yulong Yin ◽  
...  
Keyword(s):  
Growth Performance ◽  
Nitrogen Content ◽  
Biochemical Parameters ◽  
Average Daily Gain ◽  
Carcass Traits ◽  
Serum Biochemical Parameters ◽  
Final Body Weight ◽  
Fecal Nitrogen ◽  
Serum Biochemical ◽  
Mini Pigs

The Huanjiang mini-pig is a Chinese local breed and, the optimal dietary crude protein (CP) level for this breed is still unknown. Therefore, the present study was conducted to investigate its optimum dietary CP level upon the growth performance, serum biochemical parameters, fecal nitrogen content, and carcass traits. Three independent trials with 360 pigs were included. A total of 220 pigs (5.32 ± 0.46 kg) were fed ad libitum, either a 14, 16, 18, 20, or 22% CP diet from about 5- to 10-kg (trial 1); 84 pigs (11.27 ± 1.43 kg) were fed either a 12, 14, 16, 18, or 20% CP diet from about 10- to 20-kg (trial 2); and 56 pigs (18.80 ± 2.21 kg) were fed either a 10, 12, 14, 16, or 18% CP diet from about 20- to 30-kg (trial 3). In trial 1, as dietary CP levels increased, the feed-to-gain ratio (F/G) quadratically decreased (p &lt; 0.05) and was minimal at the 18.42% CP level. The average daily feed intake (ADFI) and final body weight (BW) were not affected by dietary CP levels while the fat percentage decreased (p &lt; 0.05). Besides, a linear decrease in slaughter rate (p = 0.06) and a linear increase in bone percentage (p &lt; 0.05), serum urea nitrogen (UN) (P &lt; 0.05), and fecal nitrogen content (p = 0.07) of pigs were observed. In trial 2, as dietary CP levels increased, the average daily gain quadratically increased (p &lt; 0.05) and was maximum at the 16.70% CP level. The slaughter rate linearly decreased (p &lt; 0.05) whereas the skin rate, serum UN, and NH3-N increased (p &lt; 0.05) linearly, as well as fecal nitrogen content (p = 0.06). In trial 3, as dietary CP levels increased, the F/G increased (p &lt; 0.05), while the ADFI and ADG quadratically decreased (p &lt; 0.05) and was maximum at nearly 14.00% CP level. The bone percentage and serum UN increased (p &lt; 0.05) linearly but the slaughter rate decreased (P &lt; 0.05) linearly, and the fecal nitrogen content quadratically decreased (p = 0.07) whereas the albumin increased (p &lt; 0.05) quadratically. Taken together, the optimal dietary CP levels for growth performance of Huanjiang mini-pigs from 5- to 10-kg, 10- to 20-kg, and 20- to 30-kg were 18.42, 16.70, and 14.00%, respectively.

Effect of Thermal Stress on Serum Biochemical and Haematological Parameters in Broiler Chicken

2017 ◽  
Vol 12 (3) ◽  
Author(s):  
A. K. Chaturvedani ◽  
Sudhir Kumar Jaiswal ◽  
Meesam Raza
Keyword(s):  
Thermal Stress ◽  
Treatment Group ◽  
Biochemical Parameters ◽  
Broiler Chicken ◽  
Room Temperature ◽  
Haematological Parameters ◽  
Control Group ◽  
Serum Biochemical Parameters ◽  
Serum Biochemical

The present study was conducted to assess the effects of thermal stress on the serum biochemical and haematological parameters in broiler chicken. Forty CARIBRO- Vishal broiler chicken were divided into two groups with twenty birds each. The control group was kept at room temperature and treatment group was exposed to thermal stress under 40±1 °C for 4 hours at 35 day of age. The exposure of thermal stress significantly increased (P less than 0.05) the value of serum biochemical parameters (glucose, cholesterol and triglyceride), heterophills, H/L ratios and basophills, however the value of total leukocyte, haemoglobin, haematocrit value, and monocytes decreased significantly (P less than 0.05).

​A Study on Alteration in Serum Biochemical Parameters in Colibacillosis Affected Diarrhoeic Cattle Calves

2021 ◽  
Author(s):  
T.C. Nayak ◽  
A.P. Singh ◽  
A. Chahar ◽  
Savita . ◽  
R. Yadav ◽  
...  
Keyword(s):  
Biochemical Parameters ◽  
Total Antioxidant Status ◽  
Stress Index ◽  
Control Group ◽  
Serum Biochemical Parameters ◽  
Serum Samples ◽  
Clinically Normal ◽  
Serum Biochemical ◽  
Result Analysis ◽  
G Ratio

Background: The objective of the present study was to evaluate the changes in serum biochemical parameters in colibacillosis affected diarrhoeic cattle calves below one month of age. Methods: The study was undertaken at Veterinary Clinical Complex, College of Veterinary and Animal Science, Rajasthan University of Veterinary and Animal Sciences, Bikaner, Rajasthan, India, during the period from September 2018 to March 2019. A total of 32 calves affected with colibacillosis confirmed on the basis of Multiplex PCR (for presence of K99, Stx1 and eaeA genes of E. coli) and eight clinically normal healthy calves (as control) were taken to investigate the serum biochemical profiles. Result: Analysis of serum samples of calves affected with colibacillosis revealed significant increase in the values of total protein, albumin, globulin, A/G ratio, blood urea nitogen, creatinine, potassium, total oxidant status andoxidative stress index while there is a significant decrease in the values of glucose, sodium, chloride, bicarbonate, IgG, IgM and total antioxidant status. There were no significant changes observed in the values of ALP, AST and ALT in affected calves as compared to healthy control group of calves.

scholarly journals Influence of Hempedu bumi (Andrographis paniculata) on serum biochemical parameters and liver morphology in broiler chickens

2018 ◽  
Vol 3 (4) ◽  
Author(s):  
Masnindah Malahubban ◽  
Zakry Fitri Ab Ab Aziz
Keyword(s):  
Biochemical Parameters ◽  
Broiler Chickens ◽  
Basal Diet ◽  
Normal Structure ◽  
Andrographis Paniculata ◽  
Control Group ◽  
Serum Biochemical Parameters ◽  
Treatment Groups ◽  
Liver Morphology ◽  
Serum Biochemical

Serum biochemical parameters data was evaluated in broilers fed diets supplemented with  hempedu bumi (Andrographis paniculata, AP) ground leaf. Birds (n = 160) were assigned in four treatment groups with five replication and each group contain eight birds. Broilers in the control group were fed the basal diet without additives, the group dietary treatments, Diet AP2 (Basal diet + 2g/kg Andrographis paniculata); Diet AP4 (Basal diet + 4g/kg Andrographis paniculata) and Diet AP8 (Basal diet + 8g/kg Andrographis paniculata). During day-21 and day-42, five birds from each treatment groups were randomly selected for serum biochemical analysis which involve pancreatic, renal, and hepatic functions (aspartate transaminase (AST), alkaline transaminase (ALT), alkaline phosphatase (ALP), glucose, cholesterol, triglycerides, total protein, albumin, urea, sodium, potassium, chlorine, and globulins). Liver morphology was determined after slaughtering two birds and collected the liver samples. Based on these results AP at 8g/kg diet lowered serum cholesterol, glucose and triglycerides. It also maintain the normal structure of liver indicating that no toxic effect from AP supplementation at a rate up to 8 g/kg, it also that AP lowered ALP and ALT in blood of chicken. In conclusion, supplementation of AP at 8g/kg in diet its beneficial effects on health and safe for broiler chicken production.

scholarly journals Sexual Maturity Promotes Yolk Precursor Synthesis and Follicle Development in Hens via Liver-Blood-Ovary Signal Axis

Animals ◽  
2020 ◽  
Vol 10 (12) ◽  
pp. 2348
Author(s):  
Zhifu Cui ◽  
Felix Kwame Amevor ◽  
Qian Feng ◽  
Xincheng Kang ◽  
Weizhen Song ◽  
...  
Keyword(s):  
Biochemical Parameters ◽  
Fatty Acid Synthase ◽  
Density Lipoprotein ◽  
Reproductive Hormones ◽  
The Body ◽  
Low Density ◽  
Serum Biochemical Parameters ◽  
Functional Changes ◽  
Precursor Synthesis ◽  
Serum Biochemical

Several reproductive hormones were reported to be involved in regulating egg yolk precursor synthesis in chickens; however, the mechanism that shows how the liver-blood-ovary signal axis works in relation to age changes has not been reported yet. Therefore, in this study, we observe the morphology and histology of the liver and ovary and determine the serum biochemical parameters and the expression abundance of the critical genes from d90 to 153. Results show that the body weight and liver weight were significantly increased from d132, while the ovary weight increased from d139. Aside from the increase in weight, other distinct changes such as the liver color and an increased deposition of large amounts of yolk precursors into the ovarian follicles were observed. On d139, we observed small fatty vacuoles in the hepatocytes. The results of serum biochemical parameters showed a significant increase in the estradiol (E2) level, first on d125, and then it reached its peak on d132. Meanwhile, the levels of follicle-stimulating hormone (FSH) increased initially and then remained at a high level from d146 to d153, while the levels of luteinizing hormone (LH) increased significantly on d132 and reached the top level on d153. Moreover, the levels of lecithin (LEC), vitellogenin (VTG), very low density lipoprotein y (VLDLy), triglyceride (TG), and total cholesterol (TC) were significantly increased at d125 and were close from d146 to d153. The mRNA and protein expression of estrogen receptor-alpha (ER-α) and E2 levels in the liver and serum, respectively, showed similar changes. Moreover, with reference to an increase in serum E2 level, the mRNA expression of genes related to yolk precursor synthesis (very low density apolipoprotein-II, ApoVLDL-II) and vitellogenin-II (VTG-II), lipogenesis (fatty acid synthase, FAS), and lipid transport (microsomal triglyceride transport protein, MTTP) in the liver showed up-regulation. These results suggest that the correlation between liver-blood-ovary alliances regulate the transport and exchange of synthetic substances to ensure synchronous development and functional coordination between the liver and ovary. We also found that E2 is an activator that is regulated by FSH, which induces histological and functional changes in the hepatocytes through the ER-α pathway.

Evaluation of nanoselenium (Nano-Se) effect on hematological and serum biochemical parameters of rat in experimentally lead poisoning

2016 ◽  
Vol 36 (4) ◽  
pp. 421-427 ◽  
Author(s):  
A Jafari Dehkordi ◽  
AN Mohebbi ◽  
MR Aslani ◽  
SM Ghoreyshi
Keyword(s):  
Biochemical Parameters ◽  
Thiobarbituric Acid ◽  
Male Rats ◽  
Control Group ◽  
Tbars Level ◽  
Serum Biochemical Parameters ◽  
Selenium Compounds ◽  
Significant Difference ◽  
Serum Biochemical ◽  
Hematological And Biochemical Parameters

The present study was designed to evaluate the effect of nanoselenium (Nano-Se) on hematological and biochemical parameters of rats experimentally intoxicated with lead (Pb). Thirty male rats were randomly divided into six groups as follows: the control, selenite, Nano-Se, Pb group, Pb + selenite, and Pb + Nano-Se groups. After 35 days, blood was collected from rats and hematology and serum biochemical parameters of oxidative stress were measured. The thiobarbituric acid reactive substances (TBARS) level of Pb group was significantly higher than other groups. Also, TBARS level was significantly lower in the Pb + Nano-Se group than Pb + selenite group. The serum superoxide dismutase activities were significantly lower in Pb group than the control, Pb + selenite, and Pb + Nano-Se groups. The catalase activities in the Pb group showed no significant change when compared to other groups. In the Pb group, packed cell volume was lower than the control group. A significant difference was observed between the control group and the Pb, Pb + selenite, and Pb + Nano-Se groups. In the Pb group, the numbers of white blood cell (WBC) decreased in comparison with the control group. Also, there was significant increase in WBC counts in the Pb + Nano-Se and Pb + selenite groups in comparison with Pb group. The number of lymphocytes in the Pb group decreased in comparison with the control group. By comparing the means of the Pb + Nano-Se and Pb + selenite groups together, it was determined that there were significant differences in the lymphocytes and neutrophil counts. In conclusion, usage of selenium compounds particularly Nano-Se particles inhibits the adverse effects of Pb on antioxidant activity and immune system function in the Pb poisoning.

scholarly journals Assessment of serum biochemical parameters and pathological changes in broilers with chronic aflatoxicosis fed glucomannan-containing yeast product (Mycosorb) and sodium bentonite

2015 ◽  
Vol 59 (2) ◽  
pp. 205-211 ◽  
Author(s):  
Aidin Azizpour ◽  
Navid Moghadam
Keyword(s):  
Biochemical Parameters ◽  
Fatty Degeneration ◽  
Control Group ◽  
Serum Biochemical Parameters ◽  
Pathological Changes ◽  
Negative Effects ◽  
Pathological Effect ◽  
Sodium Bentonite ◽  
Serum Biochemical ◽  
Hepatic Lesions

AbstractThe purpose of this study was to evaluate the efficacy of yeast glucomannan (YG) and sodium bentonite (SB) in reducing the toxicity in broilers fed a diet naturally contaminated with aflatoxin. Three hundred 7-day-old Ross 308 strain broilers were chosen and randomly assigned to 10 dietary treatments. Serum biochemical parameters and pathological changes in the liver were investigated at 42 d of age. Chickens fed a diet containing 250 ppb of aflatoxin displayed a decrease in uric acid, cholesterol, and triglycerides, and an increase in serum activities of AST and ALT when compared to control group. There were considerable gross and histopathological hepatic lesions (P < 0.05) in the form of small to moderate hydropic and/or fatty degeneration, bile duct hyperplasia, periportal fibrosis, cells infiltration, and congestion, in chickens fed the 250 ppb aflatoxincontaining diet. The addition of YG and SB to the aflatoxin-containing diet partially reduced the negative effects of aflatoxin. The 0.1% YG supplementation to the aflatoxin-contaminated diet significantly prevented the pathological effect of aflatoxin on serum biochemical parameters and liver, and was found to be more effective than other treatments.

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