scholarly journals Predictor Variables for Elevated Mood and Activity in Hypomania and Self-Actualization

2021 ◽  
Vol 1 (13) ◽  
pp. 28-32
Author(s):  
Andrii Zaiets ◽  
Keyword(s):  
Bipolar Disorder ◽  
Social Stigma ◽  
Bipolar Affective Disorder ◽  
Psychosocial Care ◽  
Assessment Tools ◽  
Self Actualization ◽  
The Difference ◽  
High Level ◽  
Positive Direct ◽  
Methodological Guidelines

The issue of overdiagnosis of hypomanic episodes is relevant due to their borderline nature. Diagnostic criteria describing elevated mood and activity, high self-esteem and productivity, is partly resembling a healthy process of self-actualization, which on the one hand leads to the already mentioned overdiagnosis, and on the other – to the social stigma of patients with bipolar disorder and medical and social prejudice against the elevated mood and activity they display. As part of this work, using correlation and regression, differentiation of high mood and high activity predictors is made in groups of people with a high level of self-actualization (n = 25) and patients diagnosed with the bipolar affective disorder without comorbidity (n = 24). A sample of healthy individuals with a normal level of self-actualization (n = 110) was also involved to control side variables and compare means. The following assessment inventories are used to collect data: Personal Orientation Inventory (Shostrom, 1963 – in the adaptation of SAT (Aleshina, Gozman, Zaika & Kroz, 1984)), shortened version of MMPI Mini-Mult (Zaitsev, Kozyula, 1981), FPI-B (Hampel & Selg, 1963 – adapted by Krylov, Ronginsky, 1989). The regression of the "hypomania" scale, Mini-Mult, as a dependent variable, showed different groups of predictors for the two studied samples. The statistics are summarized as a model of the relationship between elevated mood and activity predictors for the two groups. Significant differences in the configuration and elements of the linkages indicate the possibility of further development of this problem to create assessment tools and methodological guidelines for psychosocial care for groups at risk of developing or recurrence of bipolar disorder. Mainly, the difference in predicting variables consists of highly negative relation of cognitive needs to hypomania in the BAD group with highly positive direct affection of "schizoid" variable of Mini-Mult, whereas hypomanic trait in the self-actualizing group is affected by "schizoid" variable indirectly and is mainly subject of effect for "existential flexibility" and "time competence" variables.

scholarly journals Peculiarities of expression indicators and accentuated personality traits in men with psoriasis without taking into account somatotype and in representatives of meso- and endo-mesomorphic somatotypes

2021 ◽  
Vol 25 (4) ◽  
pp. 540-544
Author(s):  
Obadeh Bassam Abdel-Rahman Al-Qaraleh ◽  
V. I. Stepanenko ◽  
T. G. Kryvonis ◽  
V. S. Shkolnikov ◽  
S. V. Prokopenko
Keyword(s):  
Personality Traits ◽  
Social Stigma ◽  
Postgraduate Education ◽  
Pathological Process ◽  
The Body ◽  
Individual Traits ◽  
Clinical Center ◽  
The Difference ◽  
High Level ◽  
Medical University

Annotation. Exacerbation and aggravation of psoriasis increases the chances of neurosis, depression, can significantly impair mental health through social stigma and leads to social isolation and maladaptation, a significant reduction in quality of life. Studying this problem from the standpoint of comparative assessment of the distribution of character accentuations in patients with different dermatoses can provide insight into how a certain level of adequacy of psychological adaptive response is associated with organic pathological process or genetically existing expression of certain traits. The aim of the study was to found the features of indicators of expression and features of accentuated personality traits in men with psoriasis without taking into account somatotype and in representatives of meso- and endo-mesomorphic somatotypes. Men aged 22 to 35 years, patients with psoriasis (n=100, including 32 with mild and 68 with severe course) at the Department of Skin and Venereal Diseases with a course of postgraduate education National Pirogov Memorial Medical University, Vinnytsya and Military Medical Clinical Center of the Central Region, conducted an anthropometric survey by V. V. Bunak Estimation of the expression and features of accentuated personality traits made according to G. Shmishek The reliability of the difference between the values between the independent quantitative values was determined using the U-Mann-Whitney test. In healthy subjects, taking into account and without taking into account the somatotype, it is seen that the type of physique did not significantly affect the severity of individual traits and their combinations in this group of people. With the increase in the course of psoriasis among subjects without somatotype, there is a decrease in the percentage of persons with hyperthymic and demonstrative and an increase – with emotional, pedantic, anxious, cyclothymic, excitable, dysthymic and exalted type of character accentuation; among patients of mesomorphic somatotype there is a decrease in the percentage of people with stuck and demonstrative and an increase – with emotional, pedantic, anxious, cyclothymic, excitable, dysthymic and exalted type of character accentuation; among patients of endo-mesomorphic somatotype there is a decrease in the percentage of people with hypertension and an increase – with stuck, demonstrative and excitable type of character accentuation. All this maintains a pathologically high level of affective tension, which disrupts the autonomic balance in the body, can be a pathogenic factor in the development of psychosomatic illness and leads to ineffective treatment of psoriasis.

scholarly journals Transtorno afetivo bipolar: sentimentos, estigmas e limitações

2019 ◽  
Vol 13 ◽  
Author(s):  
Hérica Dayanne De Sousa Moura ◽  
Jefferson Abraão Caetano Lira ◽  
Mônica Madeira Martins Ferraz ◽  
Camylla Layanny Soares Lima ◽  
Ângela Raquel Cruz Rocha
Keyword(s):  
Content Analysis ◽  
Affective Disorder ◽  
Social Stigma ◽  
Care Center ◽  
Bipolar Affective Disorder ◽  
Psychosocial Care ◽  
Psychiatric Nursing ◽  
Salud Mental ◽  
Work Family ◽  
Trastorno Bipolar

Objetivo: compreender os sentimentos, estigmas e limitações laborais, familiares e sociais do transtorno afetivo bipolar para a pessoa e o familiar cuidador. Método: trata-se de um estudo qualitativo, descritivo, em um Centro de Atenção Psicossocial, de porte II, com 12 pessoas diagnosticadas com transtorno afetivo bipolar e quatro familiares cuidadores. Obtiveram-se os dados mediante entrevista com roteiro semiestruturado, analisando-os mediante a técnica de Análise de Conteúdo na modalidade Análise de Conteúdo Temática. Resultados: identificou-se que o transtorno afetivo bipolar é visto com preconceito e carrega vários estigmas sociais, como vergonha, medo, raiva e tristeza. Expressou-se, por alguns participantes, a dificuldade em manter vínculo empregatício ou ingressar no mercado de trabalho após a manifestação do transtorno. Conclusão: compreendeu-se que o transtorno afetivo bipolar carrega a marca da cronificação e do preconceito. Descritores: Transtorno Bipolar; Saúde Mental; Enfermagem Psiquiátrica; Transtornos Mentais; Estigmas Sociais; Cuidadores. ABSTRACTObjective: to understand the feelings, stigmas and work, family and social limitations of bipolar affective disorder for the person and family caregiver. Method: this is a qualitative and descriptive study in a Psychosocial Care Center, size II, with 12 people diagnosed with bipolar affective disorder and four family caregivers. Data was obtained through interviews with semi-structured script, analyzing them using the technique of Content Analysis in the Thematic Content Analysis modality. Results: it was identified that bipolar affective disorder is viewed with prejudice and carries various social stigmas, such as shame, fear, anger and sadness. Some participants expressed the difficulty in maintaining employment or entering the labor market after the onset of the disorder. Conclusion: it was understood that bipolar affective disorder bears the mark of chronicity and prejudice. Descriptors: Bipolar Disorder; Mental Health; Psychiatric Nursing; Mental Disorders; Social Stigma; Caregivers.RESUMENObjetivo: comprender los sentimientos, estigmas y las limitaciones laborales, familiares y sociales del trastorno afectivo bipolar para la persona y el cuidador familiar. Método: se trata de un estudio cualitativo y descriptivo en un Centro de Atención Psicosocial, tamaño II, con 12 personas diagnosticadas con trastorno afectivo bipolar y cuatro cuidadores familiares. Los datos se obtuvieron mediante entrevistas con guiones semiestructurados, analizándolos en la técnica de Análisis de Contenido en la modalidad de Análisis de Contenido Temático. Resultados: se identificó que el trastorno afectivo bipolar es visto con prejuicio y conlleva varios estigmas sociales, como la vergüenza, el miedo, la ira y la tristeza. Algunos participantes expresaron la dificultad de mantener el empleo o ingresar al mercado laboral después de la manifestación del trastorno. Conclusión: se entendió que el trastorno afectivo bipolar lleva la marca de cronicidad y prejuicio. Descriptores: Trastorno Bipolar; Salud Mental; Enfermería Psiquiátrica; Trastornos Mentales; Estigma Social; Cuidadores. 

scholarly journals Examining the relationship between self-actualization and job performance via taking charge

2020 ◽  
Vol 9 (5) ◽  
pp. 74-83
Author(s):  
Nilesh Kumar ◽  
Liu Zhiqiang ◽  
Md.Yahin Hossain
Keyword(s):  
Banking Sector ◽  
Creative Performance ◽  
Cross Sectional ◽  
Individual Level ◽  
Self Actualization ◽  
Taking Charge ◽  
The Difference ◽  
High Level ◽  
The Relationship ◽  
Normal Performance

Based on Construal-level theory, this study hypothesized that self-actualization positively relates to employees’ taking charge, and self-actualization affects creative performance and normal performance through taking charge positively, but the effect is different. The authors selected a cross-sectional design to investigate interrelations amongst study variables at two different time points with the interval of one month, and surveyed 417 team members and 186 immediate team leaders in the banking sector in Pakistan. The authors used individual-level data to evaluate the validity and test the proposed relationships by using Mplus. They revealed that self-actualization affects taking charge positively, and taking charge mediated the relationship with the difference in effect e.g. taking charge has high effect on creative performance in comparison to normal performance. The outcomes carry important implications aimed at increasing high-level self-actualization that results in taking charge, and so on leads to creative and normal performance.

Difference of [Ca2+]i Movements in Platelets Stimulated by Thrombin and TRAP: the Involvement of αIIbβ3-Mediated TXA2 Synthesis

1998 ◽  
Vol 79 (06) ◽  
pp. 1184-1190 ◽  
Author(s):  
Yoshiaki Tomiyama ◽  
Shigenori Honda ◽  
Kayoko Senzaki ◽  
Akito Tanaka ◽  
Mitsuru Okubo ◽  
...  
Keyword(s):  
Platelet Aggregation ◽  
Fibrinogen Binding ◽  
Adp Release ◽  
The Difference ◽  
Txa2 Receptor Antagonist ◽  
High Level ◽  
Inhibition Studies ◽  
Peak Increase ◽  
Second Peak ◽  
Assay Conditions

SummaryThis study investigated the difference of [Ca2+]i movement in platelets in response to thrombin and TRAP. The involvement of αIIbβ3 in this signaling was also studied. Stimulation of platelets with thrombin at 0.03 U/ml caused platelet aggregation and a two-peak increase in [Ca2+]i. The second peak of [Ca2+]i, but not the first peak was abolished by the inhibition of platelet aggregation with αIIbβ3 antagonists or by scavenging endogenous ADP with apyrase. A cyclooxygenase inhibitor, aspirin, and a TXA2 receptor antagonist, BM13505, also abolished the second peak of [Ca2+]i but not the first peak, although these regents did not inhibit aggregation. Under the same assay conditions, measurement of TXB2 demonstrated that αIIbβ3 antagonists and aspirin almost completely inhibited the production of TXB2. In contrast to thrombin-stimulation, TRAP caused only a single peak of [Ca2+]i even in the presence of platelet aggregation, and a high level of [Ca2+]i increase was needed for the induction of platelet aggregation. The inhibition of aggregation with αIIbβ3 antagonists had no effect on [Ca2+]i change and TXB2 production induced by TRAP. Inhibition studies using anti-GPIb antibodies suggested that GPIb may be involved in the thrombin response, but not in the TRAP. Our findings suggest that low dose thrombin causes a different [Ca2+]i response and TXA2 producing signal from TRAP. Endogenous ADP release and fibrinogen binding to αIIbβ3 are responsible for the synthesis of TXA2 which results in the induction of the second peak of [Ca2+]i in low thrombin- but not TRAP-stimulated platelets.

ATTITUDE TO OPEN ACCESS IN RUSSIAN SCHOLARLY COMMUNITY: 2018. SURVEY RESULTS AND ANALYSIS

2018 ◽  
Vol 1 (1) ◽  
pp. 6-21 ◽  
Author(s):  
I. K. Razumova ◽  
N. N. Litvinova ◽  
M. E. Shvartsman ◽  
A. Yu. Kuznetsov
Keyword(s):  
Open Access ◽  
Open Access Publishing ◽  
Scholarly Community ◽  
Research Areas ◽  
Survey Results ◽  
The Difference ◽  
Policies And Programs ◽  
The Uk ◽  
High Level ◽  
Access Policies

Introduction. The paper presents survey results on the awareness towards and practice of Open Access scholarly publishing among Russian academics.Materials and Methods. We employed methods of statistical analysis of survey results. Materials comprise results of data processing of Russian survey conducted in 2018 and published results of the latest international surveys. The survey comprised 1383 respondents from 182 organizations. We performed comparative studies of the responses from academics and research institutions as well as different research areas. The study compares results obtained in Russia with the recently published results of surveys conducted in the United Kingdom and Europe.Results. Our findings show that 95% of Russian respondents support open access, 94% agree to post their publications in open repositories and 75% have experience in open access publishing. We did not find any difference in the awareness and attitude towards open access among seven reference groups. Our analysis revealed the difference in the structure of open access publications of the authors from universities and research institutes. Discussion andConclusions. Results reveal a high level of awareness and support to open access and succeful practice in the open access publications in the Russian scholarly community. The results for Russia demonstrate close similarity with the results of the UK academics. The governmental open access policies and programs would foster the practical realization of the open access in Russia.

Quantitative indicators of air traffic controllers’ attitude to the danger of errors

2020 ◽  
pp. 68-78
Author(s):  
O. M. Reva ◽  
V. V. Kamyshin ◽  
S. P. Borsuk ◽  
V. A. Shulhin ◽  
A. V. Nevynitsyn
Keyword(s):  
Human Factor ◽  
Differential Method ◽  
Air Traffic ◽  
Professional Activity ◽  
Aviation Accidents ◽  
Air Traffic Controllers ◽  
The Difference ◽  
Level Of Significance ◽  
The Individual ◽  
High Level

The negative and persistent impact of the human factor on the statistics of aviation accidents and serious incidents makes proactive studies of the attitude of “front line” aviation operators (air traffic controllers, flight crewmembers) to dangerous actions or professional conditions as a key component of the current paradigm of ICAO safety concept. This “attitude” is determined through the indicators of the influence of the human factor on decision-making, which also include the systems of preferences of air traffic controllers on the indicators and characteristics of professional activity, illustrating both the individual perception of potential risks and dangers, and the peculiarities of generalized group thinking that have developed in a particular society. Preference systems are an ordered (ranked) series of n = 21 errors: from the most dangerous to the least dangerous and characterize only the danger preference of one error over another. The degree of this preference is determined only by the difference in the ranks of the errors and does not answer the question of how much time one error is more dangerous in relation to another. The differential method for identifying the comparative danger of errors, as well as the multistep technology for identifying and filtering out marginal opinions were applied. From the initial sample of m = 37 professional air traffic controllers, two subgroups mB=20 and mG=7 people were identified with statisti-cally significant at a high level of significance within the group consistency of opinions a = 1%. Nonpara-metric optimization of the corresponding group preference systems resulted in Kemeny’s medians, in which the related (middle) ranks were missing. Based on these medians, weighted coefficients of error hazards were determined by the mathematical prioritization method. It is substantiated that with the ac-cepted accuracy of calculations, the results obtained at the second iteration of this method are more ac-ceptable. The values of the error hazard coefficients, together with their ranks established in the preference systems, allow a more complete quantitative and qualitative analysis of the attitude of both individual air traffic controllers and their professional groups to hazardous actions or conditions.

ADOECIMENTO DE PROFESSORES UNIVERSITÁRIOS COM DIAGNÓSTICO DE TRANSTORNO AFETIVO BIPOLAR UMA REVISÃO DE LITERATURA

REVISTA FIMCA ◽  
2019 ◽  
Vol 6 (3) ◽  
pp. 1-6
Author(s):  
Pâmela Gomes Artioli ◽  
Natiely Souza Lima ◽  
Camila Silva
Keyword(s):  
Higher Education ◽  
Bipolar Disorder ◽  
Bipolar Affective Disorder ◽  
Physical Work ◽  
Education Professionals ◽  
Work Related ◽  
Analysis Technique ◽  
Work Routine ◽  
Teaching Area

Introdução: Com o passar dos anos, além de doenças laborais físicas, surge um novo cenário de doenças emocionais que vem afetando gradativamente profissionais da área da docência a pesquisa em questão visou identificar os transtornos mentais que mais provocam afastamento de docentes em instituições de ensino superior, (com ênfase no transtorno bipolar), onde contribuiu para se aprofundar a análise de fatores relacionados a esse tipo de transtorno. Objetivos: os objetivos deste estudo, são de realizar análise crática e reflexiva quanto ao número elevado de professores de ensino superior com o Transtorno Afetivo Bipolar, e a relação dos fatores associados a este impedimento dos profissionais, destacar também questões relativas à saúde mental, e identificar quais são as consequências que implicam na rotina de trabalho desses professores e o aumento de docentes com diagno?stico de Transtorno Bipolar. Materiais e Métodos: Quanto à fundamentação teórica, trata-se de um referencial bibliográfico ao passo que utiliza de literaturas científicas disponibilizadas por meio eletrônico. Utilizando-se como técnica de análise de dados a análise de conteúdo interpretativa. Os critérios de inclusão que foram usados são: publicações em português, entre os anos de 2000 a 2018 disponíveis na íntegra. Conclusão: Por fim chegou-se ao entendimento de que além da sobrecarga os docentes remanescentes, o adoecimento crescente dos profissionais da educação compromete a qualidade de vida desses profissionais. Introduction: Over the years, in addition to physical work-related illnesses, a new scenario of emotional diseases emerges that has gradually affected professionals in the teaching area. The research in question aimed at identifying the mental disorders that cause the most withdrawal of teachers in higher education institutions, (with emphasis on bipolar disorder), where it contributed to deepen the analysis of factors related to this type of disorder. Objectives: The objectives of this study are to perform a critical and reflexive analysis regarding the high number of teachers of higher education with Bipolar Affective Disorder, and the relation of the factors associated with this impediment of the professionals, also highlight issues related to mental health, and identify what are the consequences that imply in the work routine of these teachers and the increase of teachers diagnosed with Bipolar Disorder. Materials and Methods: Regarding the theoretical basis, it is a bibliographical reference while using scientific literatures made available electronically. The analysis of interpretive content was used as data analysis technique. The inclusion criteria that were used are: publications in Portuguese, between the years 2000 to 2018 available in full. Conclusion: Finally, it was understood that in addition to overloading the remaining teachers, the growing sickness of education professionals compromises the quality of life of these professionals.

PENGAKUAN CALABAI: SEBUAH ANALISIS INTERTEKSTUAL NOVEL PASUNG JIWA KARYA OKKY MADASARI DAN NOVEL CALABAI KARYA PEPI AL-BAYQUNIE

Jurnal KATA ◽  
2018 ◽  
Vol 2 (1) ◽  
pp. 50
Author(s):  
Krisna Aji Kusuma ◽  
Herman J Waluyo ◽  
Nugraheni Eko Wardani
Keyword(s):  
Content Analysis ◽  
Analysis Data ◽  
Qualitative Approach ◽  
The Novel ◽  
Research Results ◽  
Self Actualization ◽  
Similarities And Differences ◽  
The Difference ◽  
Descriptive Qualitative

<p><em>This study aims to describe the intertextuality relationship between the novel Pasung Jiwa by Okky Madasari and Calabai by Pepi Al-Bayqunie. The type of research is descriptive qualitative approach using content analysis. Data are collected by inventorying events that are similarities and differences, specifications on the characters, settings, plots, and themes of both text. The research results indicate that there are similar themes on the two novels, the theme of self actualization in addition with the theme of family and friendship. The same characterization are also used by both author, masculine figures with feminine soul characters. The difference between the two novels lies on the plot and setting. Pasung Jiwa uses progressive plot and Calabai uses a flash-back plot.. Okky Madasari takes Java Island as the background in the novel Pasung Jiwa, while the novel Calabai, Pepi Al-Bayqunie using the setting of Sulawesi Island. The basis of the similarity of theme and characterization supported by the similirity of events in the story shows the existence of intertextual relationship between the two novels. As a previously published work, the novel Pasung Jiwa by Okky Madasari is a hipogram and novel Calabai by Pepi A-Bayqunie as a transformational text. On the theme and characterization, the transformation of Calabai forward the hypogram, while in the plot and setting deviates his hypogram, Pasung Jiwa.</em></p><p>Penelitian ini bertujuan untuk mendeskripsikan hubungan intertekstualitas antara novel Pasung Jiwa karya Okky Madasari dan novel Calabai karya Pepi Al-Bayqunie. Jenis penelitian ini adalah deskriptif kualitatif dengan pendekatan konten analisis. Data dikumpulkan dengan menginventariskan peristiwa yang merupakan persamaan dan perbedaan, spesifikasi pada tokoh, latar, alur, dan tema dari kedua teks. Hasil penelitian ini menunjukkan bahwa terdapat kesamaan tema pada kedua novel, yaitu tema aktualisasi diri, ditambah dengan tema keluarga dan persahabatan. Penokohan yang sama juga digunakan oleh kedua penulis, yaitu tokoh maskulin dengan karakter jiwa feminin. Perbedaan kedua novel terletak pada alur dan latar. Pasung Jiwa menggunakan alur maju dan Calabai menggunakan alur campuran. Latar dalam novel Pasung Jiwa, Okky Madasari mengambil latar Pulau Jawa, sedangkan novel Calabai, Pepi Al-Bayqunie menggunakan latar Pulau Sulawesi. Dasar kesamaan tema dan penokohan didukung kesamaan peristiwa-peristiwa dalam cerita menunjukkan adanya hubungan intertekstual antara kedua novel. Sebagai karya yang terbit terlebih dahulu menjadikan novel Pasung Jiwa karya Okky Madasari adalah hipogram dan novel Calabai karya Pepi Al-Bayqunie sebagai teks transformasi. Pada tema dan penokohan, transformasi Calabai meneruskan hipogram, sedangkan pada alur dan latar menyimpangi hipogramnya, Pasung Jiwa.</p>

scholarly journals Reproducibility and Instruction Following in the Shop Floor Laboratory Work: The Case of a TMS Experiment

2021 ◽  
pp. 016224392110323
Author(s):  
Kristina Popova
Keyword(s):  
Measurement Procedure ◽  
Shop Floor ◽  
Experimental Uncertainty ◽  
Local Measurement ◽  
Replication Crisis ◽  
History Of ◽  
Per Se ◽  
The Difference ◽  
Methodological Guidelines ◽  
Local Procedure

The article addresses the production of reproducibility as a topic that has become acutely relevant in the recent discussions on the replication crisis in science. It brings the ethnomethodological stance on reproducibility into the discussions, claiming that reproducibility is necessarily produced locally, on the shop floor, with methodological guidelines serving as references to already established practices rather than their origins. The article refers to this argument empirically, analyzing how a group of novice neuroscientists performs a series of measurements in a transcranial magnetic stimulation experiment. Based on ethnography and video analysis, the article traces a history of the local measurement procedure invented by the researchers in order to overcome the experimental uncertainty. The article aims to demonstrate (1) how reproducibility of the local procedure is achieved in the shop floor work of the practitioners and (2) how the procedure becomes normalized and questioned as incorrect in the course of experimental practice. It concludes that the difference between guidelines and practical actions is not problematic per se; what may be problematic is that researchers can be engaged in different working projects described by the same instruction.

scholarly journals Transdiagnostic comparison of visual working memory capacity in bipolar disorder and schizophrenia

2021 ◽  
Vol 9 (1) ◽  
Author(s):  
Catherine V. Barnes-Scheufler ◽  
Caroline Passow ◽  
Lara Rösler ◽  
Jutta S. Mayer ◽  
Viola Oertel ◽  
...  
Keyword(s):  
Bipolar Disorder ◽  
Working Memory ◽  
Visual Working Memory ◽  
Effect Size ◽  
Working Memory Capacity ◽  
Memory Capacity ◽  
Medium Effect ◽  
Full Spectrum ◽  
Small Effect Size ◽  
The Difference

Abstract Background Impaired working memory is a core cognitive deficit in both bipolar disorder and schizophrenia. Its study might yield crucial insights into the underpinnings of both disorders on the cognitive and neurophysiological level. Visual working memory capacity is a particularly promising construct for such translational studies. However, it has not yet been investigated across the full spectrum of both disorders. The aim of our study was to compare the degree of reductions of visual working memory capacity in patients with bipolar disorder (PBD) and patients with schizophrenia (PSZ) using a paradigm well established in cognitive neuroscience. Methods 62 PBD, 64 PSZ, and 70 healthy controls (HC) completed a canonical visual change detection task. Participants had to encode the color of four circles and indicate after a short delay whether the color of one of the circles had changed or not. We estimated working memory capacity using Pashler’s K. Results Working memory capacity was significantly reduced in both PBD and PSZ compared to HC. We observed a small effect size (r = .202) for the difference between HC and PBD and a medium effect size (r = .370) for the difference between HC and PSZ. Working memory capacity in PSZ was also significantly reduced compared to PBD with a small effect size (r = .201). Thus, PBD showed an intermediate level of impairment. Conclusions These findings provide evidence for a gradient of reduced working memory capacity in bipolar disorder and schizophrenia, with PSZ showing the strongest degree of impairment. This underscores the importance of disturbed information processing for both bipolar disorder and schizophrenia. Our results are compatible with the cognitive manifestation of a neurodevelopmental gradient affecting bipolar disorder to a lesser degree than schizophrenia. They also highlight the relevance of visual working memory capacity for the development of both behavior- and brain-based transdiagnostic biomarkers.

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