Possibilities for predicting abnormal labor at the present stage

2020 ◽  
Vol 69 (5) ◽  
pp. 13-26
Author(s):  
Viktor A. Mudrov

Hypothesis/aims of study. Labor abnormalities can lead to dangerous complications for both the mother and the fetus. There are currently no effective ways to prevent abnormal uterine contractile activity. Therefore, the timeliness of diagnosis, which largely determines labor outcome, depends on the effectiveness of assessing the likelihood of the development of abnormal labor. The aim of this study was to examine the possibilities for predicting abnormal labor progression at the present stage of the development of science. Study design, materials and methods. A systematic analysis and synthesis of the literature data presented by domestic and foreign authors in the period from 1985 to 2020. Conclusion. A comprehensive approach to assessing the likelihood of the development of abnormal labor will optimize the tactics of labor management, which in the long-term will reduce the frequency of surgical delivery.

2021 ◽  
Vol 70 (5) ◽  
pp. 117-130
Author(s):  
Viktor A. Mudrov

Abnormal labor is a main cause of obstetric and perinatal complications. Impaired uterine contraction during childbirth is accompanied by an increase in the risk of fetal asphyxia, obstetric bleeding and postpartum inflammatory diseases. The frequency of diagnosed abnormal uterine contractile activity is 10-25%, which, along with the high need for operative delivery, allows for considering abnormal labor as one of the main medical and social issues of the present time. The aim of this study was to consider abnormal labor as a medical and social problem. This was achieved by using an analytical method including carrying out a detailed systematic analysis of modern domestic and foreign literature on abnormal labor. The study used databases such as eLIBRARY.RU, Scopus, PubMed, MEDLINE, ScienceDirect, and Cochrane Library from the creation until July 2021. Abnormal labor is an important medical and social issue that requires the active development of methods to predict and prevent not only violations of uterine contractility, but also their complications.


2020 ◽  
Vol 26 (6) ◽  
pp. 577-583
Author(s):  
L. A. Tuaeva ◽  
I. Z. Toguzova ◽  
S. K. Tokaeva

The presented study develops theoretical and methodological foundations for assessing the fiscal sustainability of the constituent entities of the Russian Federation in perspective.Aim. The study aims to develop a systems approach to assessing the fiscal sustainability of the constituent entities of the Russian Federation in the medium and long term.Tasks. The authors analyze the major approaches to assessing the fiscal sustainability of federal subjects and determine the significance of quantitative and qualitative assessment methods in the development of a methodology for assessing the fiscal sustainability of federal subjects in the medium and long term.Methods. This study uses scientific methods of cognition, analysis and synthesis, comparison and analogy, systems and institutional approaches to assess the fiscal sustainability of federal subjects.Results. The authors examine the major approaches to assessing the fiscal sustainability of federal subjects developed by Russian scientific schools and disciplines; approaches used by state and local authorities; approaches to assessing the fiscal sustainability of federal subjects used by international and national rating agencies; foreign experience. In general, this implies the development of a universal system of indicators for assessing the fiscal sustainability of federal subjects.Conclusions. It is substantiated that under the current conditions of new challenges, particularly in the context of the coronavirus pandemic, it is necessary to assess the long-term balance and sustainability of the budgets of federal subjects using a systems approach based on quantitative and qualitative methods, making allowance for the medium- and long-term prospects to make efficient management decisions at different levels of the economic system.


2019 ◽  
Vol 11 (4) ◽  
pp. 315-328
Author(s):  
Sergey Aleksandrovich Mikhailov

This article deals with the issue of North-Eastern India, its current social and economic problems in the context of long-term demonstrations of the ethnic separatism. The main aim of the research implies systematic analysis and identification of key factors and reasons perpetuating separatism in NER as well as resource search which determines Indian strategy in solving this problem. The first part of the article is devoted to separatism peculiarities in the region which remains withdrawn and underexplored in many respects. Apart from this, the author provides a quite detailed analysis of negative mentality of the certain part of NER population which justifiably reproaches New Delhi for “discrimination” and inability to solve many problems of the region. Then the author paid the detailed attention to these problems of NER modern society (ethnic, demographic, economic, transport, social etc.) as well as measures undertaken by the Indian government for its settlement.


Author(s):  
Patrick Alexander Wachholz ◽  
Deborah Cristina De Oliveira ◽  
Kathryn Hinsliff-Smith ◽  
Reena Devi ◽  
Paulo José Fortes Villas Boas ◽  
...  

This scoping review aimed to explore the characteristics, strengths, and gaps in research conducted in Brazilian long-term care facilities (LTCFs) for older adults. Electronic searches investigating the residents (≥60 years old), their families, and the LTCF workforce in Brazil were conducted in Medline, EMBASE, LILACS, and Google Scholar, within the timescale of 1999 to 2018, limited to English, Portuguese, or Spanish. The reference lists were hand searched for additional papers. The Mixed Methods Appraisal Tool (MMAT) was used for critical appraisal of evidence. Data were reported descriptively considering the study design, using content analysis: 327 studies were included (n = 159 quantitative non-randomized, n = 82 quantitative descriptive, n = 67 qualitative, n = 11 mixed methods, n = 6 randomized controlled trials, and n = 2 translation of assessment tools). Regardless of the study design, most were conducted in a single LTCF (45.8%), in urban locations (84.3%), and in non-profit settings (38.7%). The randomized trials and descriptive studies presented the lowest methodological quality based on the MMAT. This is the first review to provide an overview of research on LTCFs for older people in Brazil. It illustrates an excess of small-scale, predominantly qualitative papers, many of which are reported in ways that do not allow the quality of the work to be assured.


Thorax ◽  
2019 ◽  
Vol 74 (7) ◽  
pp. 715-717 ◽  
Author(s):  
Jesus Gonzalez-Bermejo ◽  
Jean-Paul Janssens ◽  
Claudio Rabec ◽  
Christophe Perrin ◽  
Frédéric Lofaso ◽  
...  

Episodes of patient-ventilator asynchrony (PVA) occur during acute and chronic non-invasive positive pressure ventilation (NIV). In long-term NIV, description and quantification of PVA is not standardised, thus limiting assessment of its clinical impact. The present report provides a framework for a systematic analysis of polygraphic recordings of patients under NIV for the detection and classification of PVA validated by bench testing. The algorithm described uses two different time windows: rate asynchrony and intracycle asynchrony. This approach should facilitate further studies on prevalence and clinical impact of PVA in long-term NIV.


Author(s):  
Antonina Diachenko ◽  
Yilia Palamarchuk ◽  
Mykola Maievsky ◽  
Serhii Ilchenko ◽  
Eduard Syvokhop ◽  
...  

According to the Results of monitoring of Internet resources, analysis of Scientific-Methodical, Special and reference literature, members of the Research Group established, that the issue of implementation (determination of effectiveness) of Modern Scientific tools, as well as Technical means of Training that provide a System of long-term training of athletes specializing in Martial Arts – is devoted to an insufficient number of Scientific and Methodological works. This requires Further Scientific Research and emphasizes the relevance and Practical component of the chosen area of Research. The main Purpose of Scientific Research is to determine the effectiveness of modern Scientific tools ("VKS Katsumoto" and "Visual 3D") in the System of long-term training of wrestlers (on the example of athletes who specialize in Sambo wrestling). In the process of Research and Analytical work, the following Research methods were used: abstraction, Analysis and Synthesis, induction and deduction, modeling, mathematical and statistical, etc. As a Result of Empirical Research, the effectiveness of modern Scientific tools has been determined "VKS Katsumoto" and "Visual 3D" in the System of long-term training of athletes specializing in Sambo (Sports and Combat direction). Prospects for Further Scientific Research in the chosen direction of Research include a comparative analysis of the performance of Ukrainian sambo wrestlers at the 2021 World Cup using modern Scientific tools (Technical Teaching Aids).


2017 ◽  
pp. 69-72
Author(s):  
N.V. Abbasova ◽  
◽  
E.M. Aliyeva ◽  
V.A. Akhmed-zade ◽  
A.Dj. Ismailova ◽  
...  

The objective: to study the contractile activity of the uterus in pregnant with mild preeclampsia at labor. Patients and methods. Was studies contractile activity of the uterus during the labor in 93 pregnant with mild preeclampsia. The average age of women was 25.24±0.42 (17–37 years). The duration of the clinical manifestation of mild preeclampsia was 3.2±0.1 (1 week). The contractile activity of the uterus was evaluated by the method of external cardiotocography. Results.There was confirmed, that pregnant with mild preeclampsia had high indicators of uterine contractile activity at the latent phase, including intense of the cramps 43.78±2.32 mm Hg , duration of the cramps – 28.32±1.1 s, dutation of relaxation – 43.44±1.46 s, total duration of the cramps – 71.76±1.27 s, duration of the uterine cycle – 66.55±0.28 s. And this leads to significant decreasing of the duration of the latent phase 1.24±0.11 hour, and decreasing of the total labor time (9.18±0.22 hours) appropriately. Conclusion. In parturient women with mild preeclampsia, high rates of contractile activity of the uterus in the latent phase, what significantly reduce the duration of the latent phase, and the total duration of labor as well. Key words: mild preeclampsia, contractile activity of the uterus, latent phase of the labor, active phase of the labor, intranatal cardiotocography.


Trials ◽  
2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Marc-Eric Nadeau ◽  
Justine L. Henry ◽  
Todd C. Lee ◽  
Émilie Bortolussi-Courval ◽  
Carole Goodine ◽  
...  

Abstract Background Medication overload or problematic polypharmacy is a major problem causing widespread harm, particularly to older adults. Taking multiple medications increases the risk of potentially inappropriate medications (PIMs), and residents in long-term care (LTC) are frequently prescribed 10 or more medications at once. One strategy to address this problem is for the physician and/or pharmacist to perform regular medication reviews; however, this process can be complicated and time-consuming. With a prescription review, medications may be decreased, changed, or stopped altogether. MedReviewRx is a software that runs an analysis using deprescribing rules to produce a report to guide medication reviews addressing medication overload for residents in LTC. Methods This study will employ a mixed methods effectiveness-implementation hybrid type 2 study design. To measure effectiveness, a stepped wedge cluster randomized trial design is planned, which allows us to approximate a randomized clinical trial. Approximately 1000 residents living in LTC will be recruited from five facilities in New Brunswick. The study will begin with 3 months of baseline data on rates of deprescribing. Thereafter, every 3 months a new cluster will enter the intervention mode. The intervention consists of medication reviews augmented with the MedReviewRx software, which will be used by staff and clinicians in the facilities. The estimated study duration is 18 months and the main outcome will be the proportion of patients with one or more PIMs deprescribed (reduced/stopped or changed to a safer alternative) in the 90 days following a prescription review. The goal is to study the impact of MedReviewRx on medication overload among older adults living in LTC. In typical fashion of a stepped wedge cluster randomized trial, each cluster acts as an internal control (before and after) as well as a control for the other clusters (external control). Qualitative data collected will include resident/caregiver attitudes towards deprescribing and semi-structured interviews with staff working in the long-term care homes. Discussion This study design addresses issues with seasonality and allows all clusters to participate in the intervention, which is an advantage when the intervention is related to quality improvement. This study will provide valuable information on PIM use, cost savings, and facilitators and challenges associated with medication reviews and deprescribing. This study represents an important step towards understanding and promoting tools to guide safe and rational reduction of PIM use among older adults. Trial registration NCT04762303, Registered February 21, 2021.


2020 ◽  
Vol 02 (12) ◽  
pp. 100-112
Author(s):  
Nodir Khairullaevich Davlatov ◽  
◽  
◽  

This article presents the results of long-term stratigraphic studies on the territory of the Kuldzhuktau mountains. Schemes for the division and correlation of Devonian deposits have been created based on complete biostratigraphic data that most effectively reflect the geological age of local stratigraphic units and their reliable correlation with geological age. The tier units of the International Devonian Stratigraphic Scale are substantiated at the present stage of research. Due to the widespread use of conodonts, it was possible to clarify the physical and age volumes, as well as the sequence of Devonian deposits in the territory of Kuldzhuktau, and almost completely reconstruct the Devonian section.


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