Lipase for infectious diseases

2021 ◽  
Vol 20 (5) ◽  
pp. 544-544
Author(s):  
V. G.
Keyword(s):  
Infectious Diseases ◽  
Lipolytic Enzyme ◽  
Short Time

Prof. Steinschneider (Bp. Delo, 1924, No. 6) points to the important prohyostitic significance of determining the lipolytic enzyme in the blood of free patients with infectious diseases: apparently, the more severe the disease, the more the amount of lipase in the blood decreases, when it falls below 10, - most often death occurs in a short time.

scholarly journals Vaccine prevention at the time of covid-19: the ASL Roma 4 experience

2020 ◽  
Vol 30 (Supplement_5) ◽  
Author(s):  
C Fusillo ◽  
E Galliano ◽  
G Belfiori ◽  
R Marchini ◽  
C Turci ◽  
...  
Keyword(s):  
Infectious Diseases ◽  
Home Health Care ◽  
Social Life ◽  
Health Workers ◽  
Task Force ◽  
Emergency Plan ◽  
Waiting Room ◽  
School Work ◽  
Preventive Actions ◽  
Short Time

Abstract The end of January 2020 WHO sanctioned an international public health emergency and the Italian government issued directives with urgent measures to counter and manage the epidemiological emergency: bans, suspensions of activities have profoundly changed school, work and health social life which have an impact on vaccination prevention Vaccinations Service (VS) of ASL Roma 4 vaccinates people of all ages and the healthcare professional (HP) noticed that the fear in the population is making the accesses less frequent and the vaccination coverage decrease and the infectious diseases will re-emerge. DPCM 4/3/2020 has established rules to contain the virus, the ASL task force and VS adopted and adapted them for a protected vaccination activity. Results Surgeries are cleaned more frequently and fomites have been removed. The rules were published on the ASL website, social networks, displayed on posters posted before entering the clinic and waiting rooms: vigilantes lets you enter without crowding the waiting room; only one parent enters; the adult enters alone; if you have a cough or sneeze cover your nose and mouth with a tissue or ask for the surgical mask, wash your hands with the disinfectant gel, sit only in the spaced chair. Inside the children find a nice poster with drawings to explain how to avoid the virus to be colored at home. Health care workers wear masks designed to calm children. As long as the epidemiological situation allows the vaccine prevention activity must be maintained. HP must give messages of trust for activities that are carried out safely. An emergency plan within the VS also provides the behavior to be used in the event that many health workers fall ill. At the time of Covid-2019 infection all forms of prevention are to be remodeled, not just vaccine prevention. Reducing the preventive actions could in a short time lead to the emergence of infectious diseases and not only with consequent important damages, including economic ones Key messages Healthcare professionals must give messages of trust for activities that are carried out safely. At the time of Covid-2019 infection all forms of prevention are to be remodeled, not just vaccine prevention.

scholarly journals The The paradox of contemporary Medicine

2020 ◽  
Vol 14 (1) ◽  
pp. 9-13
Author(s):  
Florindo Pirone
Keyword(s):  
Infectious Diseases ◽  
New Technologies ◽  
Heart Diseases ◽  
Great Effort ◽  
Average Life Span ◽  
The Difference ◽  
Decisive Action ◽  
Contemporary Medicine ◽  
Short Time ◽  
The 19Th Century

In the medical field, between the end of the 19th century and the half of last century, great results were obtained in the discovery of the causes (microbial agents) and cures (antibiotics) of infectious diseases, which in the previous centuries had determined catastrophic epidemics. The successes of this model of disease led to apply it in the cases of other pathologies including cardiovascular, respiratory and oncological ones. Despite the great effort during the following years, with all the innovations both in diagnostic field (sophisticated lab and instrumental tests) and in therapies (the development of numerous heart and circulatory drugs or against neoplasia), improvements have been proportionally less impressive. Compared to the first half of last century, 27 years of life have been gained, from an average life span of 55 years to 81 for men and 84 for women. The 17-year gain has been possible thanks to the decisive action on the infectious diseases, whereas the intervention on heart diseases led to a gain of 7 years of life, and that on the neoplastic ones resulted in a gain of 3/4 years. This discrepancy depends on several reasons, among which a fundamental one is the difference between the models of the infectious disease and other pathologies: the first ones are characterized by only one agent attacking the organism in a short time and can be eliminated only by one drug (the antibiotic), used for a short time as well; in the case of other diseases, the pathogens are multifactorial, the damaging actions take place over many years and possible therapies must be multiple and performed over a long period of time. There has been a shift from a simple to a complex issue, to the extent that some believe that only new technologies of artificial intelligence (AI) will be able to offer effective remedies. If we add to all this the idea that for several reasons, both socio-cultural and inherent to this discipline, Medicine has been taking on more and more reductionism and detached stands, one might understand the current perceptive paradox We have never been better, we have never felt so bad. Thus, it has become necessary to meditate upon these topics in order to better understand the real problems and possible solutions to the benefit of that essential good for everyone, our health.

scholarly journals Immunity and Viral Infections: Modulating Antiviral Response via CRISPR–Cas Systems

Viruses ◽  
2021 ◽  
Vol 13 (7) ◽  
pp. 1373
Author(s):  
Sergey Brezgin ◽  
Anastasiya Kostyusheva ◽  
Ekaterina Bayurova ◽  
Elena Volchkova ◽  
Vladimir Gegechkori ◽  
...  
Keyword(s):  
Infectious Diseases ◽  
Immune Responses ◽  
Viral Infections ◽  
Antiviral Agents ◽  
Innate Immune ◽  
Host Factors ◽  
Innate Immune Responses ◽  
Host Interactions ◽  
Translational Studies ◽  
Short Time

Viral infections cause a variety of acute and chronic human diseases, sometimes resulting in small local outbreaks, or in some cases spreading across the globe and leading to global pandemics. Understanding and exploiting virus–host interactions is instrumental for identifying host factors involved in viral replication, developing effective antiviral agents, and mitigating the severity of virus-borne infectious diseases. The diversity of CRISPR systems and CRISPR-based tools enables the specific modulation of innate immune responses and has contributed impressively to the fields of virology and immunology in a very short time. In this review, we describe the most recent advances in the use of CRISPR systems for basic and translational studies of virus–host interactions.

Mathematical modeling of the epidemic of influenza and acute respiratory viral infections processes (ARVI) in the Yaroslavl region

2021 ◽  
pp. 47-58
Author(s):  
Natalia Ur'evna Shirina ◽  
Tatiana Aleksandrovna Druzhinina ◽  
Elizaveta Sergeevna Shirina
Keyword(s):  
Infectious Diseases ◽  
Viral Infections ◽  
Statistical Significance ◽  
Process Time ◽  
Federal State ◽  
Significance Level ◽  
The Past ◽  
Sick People ◽  
Respiratory Viral Infections ◽  
Short Time

In the structure of infectious diseases in the Yaroslavl region, more than 90 % are influenza and acute respiratory viral infections (ARVI). Influenza occupies a special place among human infectious diseases. This is due to its ability to epidemic and pandemic spread in a relatively short time. In this regard, scientific research on the analysis and forecasting of probable scenarios for the development of epidemic processes is of particular importance. The work used the data of the forms of the federal state statistical observation No. 2 “Information on infectious and parasitic diseases”. Fourier analysis was used to process time series. The significance of the mathematical model was checked using the Fisher test. The table of critical values of the Fisher criterion was used to assess the statistical significance, the significance level was taken equal to 0.05. Data processing was carried out using MS Excel 2013 software. During the study of the dynamics of the epidemic process, the trend of reducing the incidence of influenza and ARVI in the Yaroslavl region over the past 36 years has been determined. The dynamics of the incidence of influenza and ARVI in the Yaroslavl region over the past 36 years has a tendency to decrease. As a result of calculations, we obtained cyclical components with periods equal to 3 and 5 years. This is due to the accumulation of people who are not immune to these infections. Mathematical calculations have confirmed the values of seasonal fluctuations in 6 and 12 months. The maximum number of sick people is recorded in the winter-spring period (February — March). In accordance with the calculations, a decrease in the incidence of influenza and ARVI in the Yaroslavl region is expected in the period from 2020 to 2022: in 2020 the number of sick people (per 100 thousand population) is predicted to be 20 962.64, in 2021 — 18 138.58.

scholarly journals TITIK MERAH: KARYA SENI YANG TERINSPIRASI DARI SEBUAH FILM THE FLU YANG DIVISUALKAN KEDALAM WUJUD KARYA TARI

2018 ◽  
Vol 7 (2) ◽  
pp. 187
Author(s):  
Hernando Saputra ◽  
Susas Rita Loravianti ◽  
Ediwar Ediwar
Keyword(s):  
Infectious Diseases ◽  
High Temperatures ◽  
Human Life ◽  
Formation Evaluation ◽  
Bird Flu ◽  
Initial Preparation ◽  
Flu Virus ◽  
Short Time

AbstrakKarya tari yang berjudul “Titik Merah”  merupakan karya tari yang terinspirasi dari film yang berjudul The Flu Produksi Servis In Hongkong By October Picture Limited. The Flu merupakan sebuah film yang menceritakan proses penyebaran penyakit flu burung disebuah kota yang bernama Bundang.Pengkarya terinspirasi setelah menonton film The Flu, sebab film ini memberi pemahaman bahwa kesehatan adalah faktor yang sangat penting dalam kehidupan manusia. Flu burung adalah salah satu penyakit yang menular yang disebabkan oleh unggas yang sangat berbahaya hingga bisa mengancam nyawa manuisa dalam waktu yang singkat. Penyebaran virus bisa melalui makanan, sentuhan, minuman, air ludah, dan virus bisa dimatikan dalam suhu yang tinggi.Metode penggarapan dilakukan mulai dari menonton berulang kali film yang menjadi sumber insprirasi, wawancara, serta membaca buku-buku yang bersangkutan dengan oenyakit virus flu burung. Kemudian dilanjutkan dengan proses penciptaan antara lain persiapan awal, eksplorasi, improvisasi, komposisi/pembentukan, evaluasi serta persiapan pertunjukan. Untuk melahirkan dalam sebuah koreografi, pengkarya menggunakan tema kehidupan yang menggunakantipeabstrak.           Kata Kunci:koreografi tari, virus flu burung, kesehatan. AbstractThe dance work entitled “ Titik Merah” is a dance creation inspired from a film entitled “ The Flu” produced by Servis In Hongkong By October Picture Limited. The Flu is a film that tells the process of the spread  of bird flu disease in a  city named Bundang. The choreographer was inspired after watching this film, because it provides an understanding that health is a very important factor in human life. Bird Flu is which one of the infectious diseases caused by very dangerous poultry that can threaten the human life in a short time. The cause of the virus can be through by food, touch, drink, saliva , and the viruses can be killed through high temperatures. The method of cultivation starts from watching repeatedly the film that became the source if inspiration, interview, and read the books concerned with this disease. Then continuing or produced with thecreation process such as initial preparation, exploration, improvisation, composition or formation, evaluation and preparation of the show. To give birth in this choreography, the choreographer uses a life theme that uses an abstract type. Keywords:dance choreography, bird flu virus, health.

What the replication reformation wrought

2018 ◽  
Vol 41 ◽  
Author(s):  
Barbara A. Spellman ◽  
Daniel Kahneman
Keyword(s):  
Reform Movement ◽  
Short Time

AbstractReplication failures were among the triggers of a reform movement which, in a very short time, has been enormously useful in raising standards and improving methods. As a result, the massive multilab multi-experiment replication projects have served their purpose and will die out. We describe other types of replications – both friendly and adversarial – that should continue to be beneficial.

Periodic Variations in the Coronal Green Line Intensity and their Connection with the White-light Coronal Structures

2000 ◽  
Vol 179 ◽  
pp. 197-200
Author(s):  
Milan Minarovjech ◽  
Milan Rybanský ◽  
Vojtech Rušin
Keyword(s):  
Time Resolution ◽  
White Light ◽  
Short Time Scale ◽  
High Time Resolution ◽  
Green Line ◽  
Periodic Intensity ◽  
Coronal Green Line ◽  
Significant Intensity ◽  
Short Time ◽  
Coronal Structures

AbstractWe present an analysis of short time-scale intensity variations in the coronal green line as obtained with high time resolution observations. The observed data can be divided into two groups. The first one shows periodic intensity variations with a period of 5 min. the second one does not show any significant intensity variations. We studied the relation between regions of coronal intensity oscillations and the shape of white-light coronal structures. We found that the coronal green-line oscillations occur mainly in regions where open white-light coronal structures are located.

Destruction of Actin Filaments by Osmium Tetroxide

1977 ◽  
Vol 35 ◽  
pp. 466-467
Author(s):  
P. Maupin-Szamier ◽  
T. D. Pollard
Keyword(s):  
Actin Filaments ◽  
Time Course ◽  
Osmium Tetroxide ◽  
Rabbit Muscle ◽  
Muscle Actin ◽  
Sodium Phosphate Buffer ◽  
Transmission Electron ◽  
The Difference ◽  
Rates Of Decay ◽  
Short Time

We have studied the destruction of rabbit muscle actin filaments by osmium tetroxide (OSO4) to develop methods which will preserve the structure of actin filaments during preparation for transmission electron microscopy.Negatively stained F-actin, which appears as smooth, gently curved filaments in control samples (Fig. 1a), acquire an angular, distorted profile and break into progressively shorter pieces after exposure to OSO4 (Fig. 1b,c). We followed the time course of the reaction with viscometry since it is a simple, quantitative method to assess filament integrity. The difference in rates of decay in viscosity of polymerized actin solutions after the addition of four concentrations of OSO4 is illustrated in Fig. 2. Viscometry indicated that the rate of actin filament destruction is also dependent upon temperature, buffer type, buffer concentration, and pH, and requires the continued presence of OSO4. The conditions most favorable to filament preservation are fixation in a low concentration of OSO4 for a short time at 0°C in 100mM sodium phosphate buffer, pH 6.0.

Effect of a Complex Heat Treatment on the Structure of 300M Steel

1981 ◽  
Vol 39 ◽  
pp. 312-313
Author(s):  
R. Padmanabhan ◽  
W. E. Wood
Keyword(s):  
Heat Treatment ◽  
Metal Carbides ◽  
Austenite Grain Size ◽  
300M Steel ◽  
Heat Treated ◽  
Strain Fracture ◽  
Prior Austenite Grain Size ◽  
Short Time ◽  
Final Tempering ◽  
Similar Yield

Intermediate high temperature tempering prior to subsequent reaustenitization has been shown to double the plane strain fracture toughness as compared to conventionally heat treated UHSLA steels, at similar yield strength levels. The precipitation (during tempering) of metal carbides and their subsequent partial redissolution and refinement (during reaustenitization), in addition to the reduction in the prior austenite grain size during the cycling operation have all been suggested to contribute to the observed improvement in the mechanical properties. In this investigation, 300M steel was initially austenitized at 1143°K and then subjected to intermediate tempering at 923°K for 1 hr. before reaustenitizing at 1123°K for a short time and final tempering at 583°K. The changes in the microstructure responsible for the improvement in the properties have been studied and compared with conventionally heat treated steel. Fig. 1 shows interlath films of retained austenite produced during conventionally heat treatment.

Transmission Electron Microscopy of an Aluminum-Silver-Stainless Steel Solid State Bond

1985 ◽  
Vol 43 ◽  
pp. 172-173
Author(s):  
M. J. Carr ◽  
J. F. Shewbridge ◽  
T. O. Wilford
Keyword(s):  
Electron Microscopy ◽  
Transmission Electron Microscopy ◽  
Solid State ◽  
Specimen Preparation ◽  
Dimensional Control ◽  
Tem Analysis ◽  
Metal Parts ◽  
Dissimilar Metal ◽  
Transmission Electron ◽  
Short Time

Strong solid state bonds are routinely produced between physical vapor deposited (PVD) silver coatings deposited on sputter cleaned surfaces of two dissimilar metal parts. The low temperature (200°C) and short time (10 min) used in the bonding cycle are advantageous from the standpoint of productivity and dimensional control. These conditions unfortunately produce no microstructural changes at or near the interface that are detectable by optical, SEM, or microprobe examination. Microstructural problems arising at these interfaces could therefore easily go undetected by these techniques. TEM analysis has not been previously applied to this problem because of the difficulty in specimen preparation. The purpose of this paper is to describe our technique for preparing specimens from solid state bonds and to present our initial observations of the microstructural details of such bonds.

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