scholarly journals MELATONIN EXCHANGE AT MULTIMORBID CARDIOVASCULAR PATHOLOGYWITH ANXIETY AND DEPRESSIVE DISORDERS IN YOUNG AND MIDDLE-AGED MEN

2015 ◽  
Vol 7 (3) ◽  
pp. 60-65
Author(s):  
M A Aflitonov ◽  
S A Partsernyak ◽  
A N Mironenko ◽  
A S Partsernyak ◽  
A A Topanova
Keyword(s):  
Standard Therapy ◽  
Depressive Disorders ◽  
Severe Depression ◽  
Simple Random Sampling ◽  
Reference Intervals ◽  
Test Methods ◽  
Mild Depression ◽  
Before And After ◽  
Group 2 ◽  
Biochemical Indices

Evaluate melatonin (MT) patterns excretion at multimorbid cardiovascular pathology (MCVP) (coronary artery disease (CAD), hypertension, metabolic syndrome (MS)) with non-psychot- ic mental disorders (NPMD) anxiety/ depressive type. Identify the effectiveness of visual-auditory ef- fects in the treatment of these pathologies. Design and methods: The study included 70 men (mean age 37,46±6,74) with MCVP divided into 4 groups by simple random sampling, and 20 healthy men (mean age 38,3±6,73 g). Patients in Group 1 (n = 22) received standard therapy CAD, hypertension and NPMD, in group 2 (n = 25) standard therapy CAD, hypertension, NPMD and visual-auditory correction. Patients of group 3 (n = 23) received standard therapy CAD, hypertension, NPMD, visual-auditory correction and psychotherapy. Used in the study: complex psychological test methods and laboratory-instrumental evaluation of the cardiovascular system. Definition of 6-sulfatoxymelatonin (6-SMT) performed by ELI- SA using kits BÜHLMANNEK-M6S. Results: Identified change normal «dipper» pattern to «non- dip- per» and «night-peaker» (daily index blood pressure and 0-10% <0% (p <0,001) in all treatment groups. Patients 3 group observed achievement reference values of the night excretion after treatment 458±64-» 798±32 (before and after treatment, respectively) (p <0,001). In all groups after treatment was observed significantly change the type of NDP «severe depression», «clinical anxiety» to «mild depression»; «sub- clinical anxiety» (p <0,001). Conclusions: Patients with MCVP have abnormalities of MT content char- acterized by a decrease in nocturnal excretion of 6-SMT. Night pattern of 6-SMT excretion significantly correlated with severity of anxiety/ depression before and after treatment. Results of patients treated with visual auditory correction significantly better than patients of other groups (obtained reference intervals MT excretion, biochemical indices and normalization of psychological tests).

scholarly journals FIBROBLAST GROWTH FACTOR (FGF) 21 AT MULTIMORBID CARDIOVASCULAR PATHOLOGY WITH ANXIETY AND DEPRESSIVE DISORDERS IN YOUNG AND MIDDLE-AGED MEN

2015 ◽  
Vol 7 (2) ◽  
pp. 108-113
Author(s):  
A S Partsernyak ◽  
G A Proshyai ◽  
S A Partsernyak ◽  
M A Aflitonov ◽  
A N Mironenko ◽  
...  
Keyword(s):  
Standard Therapy ◽  
Depressive Disorders ◽  
Combined Therapy ◽  
Severe Depression ◽  
Fold Increase ◽  
Simple Random Sampling ◽  
Correction Method ◽  
Test Methods ◽  
Mild Depression ◽  
Cardiovascular Pathology

Evaluate (FGF) 21 at multimorbid cardiovascular pathology (MCVP) (coronary artery disease (CAd), hypertension, metabolic syndrome (MS)) with non-psychotic mental disorders (NPMd) anxiety/ depressive type. Identify the effectiveness of visual-auditory effects in the treatment of these pathologies. design and methods: The study included 70 men (mean age 37,46±6,74) with MCVP divided into 4 groups by simple random sampling, and 20 healthy men (mean age 38,3±6,73 g). Patients in Group 1 (n = 22) received standard therapy CAd, hypertension and NPMd, in group 2 (n = 25) standard therapy CAd, hypertension, NPMd and visual-auditory correction. Patients of group 3 (n =23) received standard therapy CAd, hypertension, NPMd, visual-auditory correction and psychotherapy. used in the study: complex psychological test methods and laboratory-instrumental evaluation of the cardiovascular system. definition of FGF21 performed by ELISA using kits BCM diagnostics SK00145-01 (BCM diagnostics, uSA). Results: Identified a two-fold increase in the concentration of serum FGF 21 after the course of standard therapy in the first group. In the other groups showed a statistically significant decrease FGF21 after psychopharmacological and visual-auditory therapy. In all groups after treatment was observed significantly change the type of NdP «severe depression»,«clinical anxiety» to «mild depression»; «subclinical anxiety» (p <0,001). Conclusions: FGF21 may be important biomarker for early diagnosis of metabolic abnormalities in this pathology. Results indicate benefits of combined therapy MCVP with the use of psychotropic drugs and visual-auditory correction method. Choose the method of complex treatment given the side effects of pharmacological agents.

scholarly journals HUBUNGAN DUKUNGAN SOSIAL KELUARGA DENGAN TINGKAT DEPRESI PADA LANSIA DI KELURAHAN SADING

2015 ◽  
Vol 2 (1) ◽  
Author(s):  
Gusti Ayu Trisna Parasari ◽  
Made Diah Lestari
Keyword(s):  
Social Support ◽  
Depressive Disorders ◽  
Depression Scale ◽  
Rank Correlation ◽  
Severe Depression ◽  
Sampling Technique ◽  
Simple Random Sampling ◽  
Mild Depression ◽  
Family Social Support ◽  
Social Support Scale

Elderly are age group that susceptible to depression. Depression in elderly is caused by lack of ability to adapt to changes in self as result of physical, mental and social decline. Severity of elderly depressive disorders are categorized into three levels, namely no depression, mild depression and moderate/severe depression. Family social support plays an important role in helping the elderly in adapting to the changes that occur in order to reduce the level of depression. This quantitative research with correlation approach aims to determine the relationship between family social support with level of depression in elderly in Sading Village. The samples cosisted of 233 elderly in Sading Village were taken using simple random sampling technique. This study uses two scales of measurement namely the family social support scale and the level of depression scale (Geriatric Depression Scale) adapted from Yesavage et al. (in Azizah, 2011). Family social support scale consists of 33 items with the reliability value = 0,968 and level of depression scale consists of 30 items with the reliability value = 0,948. The analysis technique used in this study is the Spearman Rank correlation. The analysis result showed that there was a significant relationship between family social support with level of depression (p = 0,000, p <0,05). The correlation r = -0.847 can be concluded that family social support has a opposite direction relationship with level of depression. This means that the higher family social support received, then the level of depression in elderly in Sading Village would be lower.   Keywords: Family Social Support, Level coefficient of Depression and Elderly

Anxiety-depressive disorders and quality of life in patients with atrial fibrillation

2020 ◽  
Vol 41 (Supplement_2) ◽  
Author(s):  
T Demenko ◽  
G.A Chumakova
Keyword(s):  
Quality Of Life ◽  
Physical Activity ◽  
Atrial Fibrillation ◽  
Correlation Analysis ◽  
Depressive Disorders ◽  
Life Assessment ◽  
Mild Depression ◽  
Group 2 ◽  
Group 1

Abstract Background Mental disorders in patients with cardiovascular disease have a significant impact on the course, the prognosis of the underlying disease and quality of life (QOL). Objective We aimed to examine the prevalence of anxiety and depressive disorders and their impact on the quality of life in patients with atrial fibrillation (AF). Materials and methods In 52 with permanent AF and 50 with paroxysmal AF patients, we administered the depression scale Tsung, the scale of situational anxiety (SA) and personal anxiety (PA) Spielberger-Hanin; QOL was assessed the SF-36 quality of life assessment scale. Correlation analysis using Spearman's rank correlation coefficient. Results The prevalence symptoms mild depression situational or neurotic genesis was 21.1% (12 patients) in Group 1 and 12.0% (6 patients) in Group 2 (p&gt;0.05). Subdepressive state was two percents of patients in Group 1 and Group 2. The incidence SA was 59.6% (31 patients) in Group 1 and 52.0% (26 patients) in Group 2. The incidence PA was 74.0% (37 patients) in Group 2 and 67.3% (35 patients) in Group 1. The average score the physical component of health (PCH) was 29,8±4,3 in Group 1, the mental component of health (MCH) – 49.5±7.4 points; p&lt;0.05. In Group 2: PCH – 44.8±6.6 points, MCH – 26.6±7.5 points; p&lt;0.05. Correlation analysis showed negative strong correlations between SA and MCH (r=−0.64, p=0.0005) and between PA and MCH (r=−0.69, p&lt;0.0001), between SA and PCH (r=−0.71, p=0.0001), between depression and PCH (r=−0.69, p=0.023). Negative statistically significant correlation between depression and MCH (r=−0.69, p=0.54) and negative medium correlation between depression and PCH (r=−0.64, p=0.23). Conclusion These findings suggest that we did not identify patients with symptoms of a true depressive (that can cause pseudodementia and influenced to complete tests). 16.5% patients with AF had mild depression of situational or neurotic genesis. Depression may be a pathogenetic factor of AF or develop because of paroxysms AF – psychological stress. More than 50% patients in Group 1 and Group 2 had an increased anxiety score. SA is more common in patients with permanent AF, probably because older people difficult to adapt to a new situation. PA is more common in patient with paroxysmal AF, probably because disease is sudden and causes anxiety. The PCH of QOL is more impairment in patients with permanent AF, because complications (for example heart failure) impairment physical activity. However, PCH also reduced in patient with paroxysmal AF, because disease is sudden may occur during physical activity. The MCH of QOL is more impairment in patients with paroxysmal AF, because waiting attack effect on mental health and social functioning. An increased level of anxiety and depression negatively affected the mental and physical health of patients with AF. Funding Acknowledgement Type of funding source: None

scholarly journals AB0167 PECULIARITIES OF INTERACTION OF CHRONIC INFLAMMATION AND DEPRESSION IN RHEUMATOID ARTHRITIS

2021 ◽  
Vol 80 (Suppl 1) ◽  
pp. 1110.1-1110
Author(s):  
A. Aleksandrov ◽  
N. Aleksandrova
Keyword(s):  
Rheumatoid Arthritis ◽  
Vitamin D ◽  
Inflammatory Cytokines ◽  
Depressive Disorders ◽  
Severe Depression ◽  
Mild Depression ◽  
Group Iii ◽  
Group I ◽  
Severity Of Depression ◽  
Pro Inflammatory Cytokines

Background:In patients with rheumatoid arthritis (RA), a high prevalence of depression and anxiety is observed, and the severity of these conditions depends on the degree of vitamin D deficiency. The role of the main mediator, with the help of which psychological and physical stress factors can contribute to the development of depression and systemic diseases, has been attributed to inflammation in recent years.Objectives:to assess the dependence of depressive disorders on vitamin D deficiency and the level of pro-inflammatory cytokines in patients with RA.Methods:88 women with a reliable diagnosis of RA (mean age 54.2 ± 12.0 years old, disease duration 9.0 [3.5; 16.0] years) were under observation. Beck’s depression inventory (BDI-II) was used to assess the presence of depressive symptoms. ELISA test was used to measure serum cytokines (IL-1, IL-6) and serum 25(OH)D levels.Results:The presence of depression was found in 66% of patients with RA. An insufficient level of 25(OH)D (<30 ng / ml) was determined in 89.8% of cases. In RA patients with no signs of depression, the level of 25(OH)D showed maximum values and significantly differed from that in the groups of patients with moderate (p = 0.028) and severe depression (p <0.001). A negative correlation (r = -0.38, n = 88, p <0.05) was established between the level of 25(OH)D and the severity of depression. A positive relationship was also found between 25(OH)D and ESR (r = 0.29, n = 73, p <0.05) and a negative relationship with the number of painful joints (r = -0.29, n = 76, p <0.05). Probably, vitamin D is indirectly involved in inflammatory processes in joints and in central sensitization, which provokes chronic pain and psychological disorders in patients with RA.The level of IL-6 in patients with RA with moderate and severe depression (n=18; 14.6 ± 6.7 pg/ml) significantly exceeded the parameters of patients with RA without depressive disorders (n=30; 9.8 ± 3.7; p = 0.003). There was also a tendency to increase IL-6 in the group of patients with moderate and severe depression compared with patients with mild depression (p = 0.06). IL-1β values significantly increased with the progression of depression (without depression – mild depression, p = 0.034; mild – moderate, p <0.001; moderate – severe depression, p = 0.044). A positive correlation of average severity was revealed between the degree of depression (according to BDI-II) and the dose of glucocorticoids (GC) at the time of the study (r = 0.33, p = 0.002). An increase in the GC dose in the short term can aggravate depressive disorders in RA patients (Table 1).Table 1.Indicators of levels of depression and IL-1β depending on the dose of GCGroup I (n=26), without GCGroup II (n=45),GC <10 mg / dayGroup III (n=17),GC ≥10 mg / dayDepression level according to BDI-II, points (Me [P25; P75])8,5[5;16]14[9;17]19[14;29] *III-IIL-1β level, pg / ml (M ± SD)4,57 ± 1,83*I-II6,04 ± 3,276,52 ± 5,16* - intergroup differences are reliable, p <0.05Patients who used GC in a daily dose of ≥10 mg / day (group III) had a higher degree of depression compared to patients with RA from group I (z = -2.98; p = 0.003). In patients with RA in the first group, the level of IL-1β was significantly higher (pI-II = 0.039) than in patients with GC prescription in minimal doses (up to 10 mg / day) (Table 1). Glucocorticoid hormones suppress pro-inflammatory cytokines. As a rule, this effect is not observed in patients with depression. This fact may indicate a violation of homeostatic mechanisms. IL-1β is thought to be the first step in the pro-inflammatory response to psychological stress and is capable of inducing a subsequent cascade of other inflammatory cytokine responses.Conclusion:Restoring the normal level of 25(OH)D in the blood serum of patients with RA can positively affect psychological indicators by reducing the severity of depression and manifestations of pain. The activation of pro-inflammatory cytokines during stress and depression suggests that suppression of the inflammatory response can also reduce the symptoms of depression in RA patients.Disclosure of Interests:None declared

scholarly journals Features of biochemical indices and content of enzymes in the serum of syphilis patients with viral hepatites B and C in the course of treatment

2021 ◽  
Vol 26 (3) ◽  
pp. 107-113
Author(s):  
S.V. Zakharov ◽  
V.K. Zakharov ◽  
V.V. Gorbuntsov
Keyword(s):  
Functional State ◽  
Biochemical Parameters ◽  
Early Stage ◽  
Serum Levels ◽  
Test Methods ◽  
Comprehensive Examination ◽  
Before And After ◽  
Biochemical Indices ◽  
Increased Activity ◽  
Latent Syphilis

Objective – before and after the treatment to determine the functional state of the liver, serum levels of enzymes and biochemical indices in syphilis patients with viral hepatites B and C. The results of the study are based on the data from a comprehensive examination of 35 patients with syphilis alone and 127 patients with syphilis co-infected with viral hepatites B and C before and after treatment. Test methods: hepatology, rheogeopathography, enzyme content and biochemical parameters determined in the serum. According to the results of radionuclide hepatology it has been established that disorders of the functional capacity of the liver already occur in the early stages of the disease. The most significant disorders have been in the patients with the prescription of infection for more than 12 months and in the patients co-infected with viral hepatites B and C. A disorder of pigment metabolism and increased activity of trans­aminases have been revealed in early latent syphilis. In co-infection with viral hepatites B and C an increase in total bilirubin, Lactate dehydrogenase, Alanine transaminase, Aspartate aminotransferase and albumin has been revealed. Dysproteinemia has been revealed in patients with early latent syphilis co-infected with hepatitis C. Patients with early latent syphilis treated with immunomodulators tend to normalize these indices. In patients with syphilis a disorder of the functional state of the liver have been revealed already at an early stage of the disease. The most pronounced disorder of biochemical parameters and activity of liver enzymes are observed in syphilis patients with viral hepatites B and C, as well as in patients with early latent syphilis only with the prescription of the infection for more than 12 months; in such a case it is advisable to use drugs affecting the immune system.

Generalized anxiety disorder comorbidities: Panic and depressive disorder

2017 ◽  
Vol 41 (S1) ◽  
pp. S486-S486
Author(s):  
M. Turki ◽  
J. Ben Thabet ◽  
N. Charfi ◽  
M. Mezghanni ◽  
M. Maalej Bouali ◽  
...  
Keyword(s):  
Anxiety Disorder ◽  
Generalized Anxiety Disorder ◽  
Depressive Disorders ◽  
Severe Depression ◽  
Cross Sectional Study ◽  
Generalized Anxiety ◽  
Mild Depression ◽  
Cross Sectional ◽  
History Of ◽  
Competing Interest

IntroductionIt has been well documented that generalized anxiety disorder (GAD) can co-occur with mood disorders and other anxious disorders, particularly panic disorder (PD). These comorbidities can complicate therapeutic management and burden the prognosis.AimTo highlight the relationship between GAD and panic and depressive disorders.MethodsWe conducted a cross-sectional study, among 250 subjects consulting in 6 primary care units in Sfax, Tunisia. These participants, randomly chosen, were asked to answer a questionnaire after their consent. The diagnosis of GAD and PD were assessed by the “Mini International Neuropsychiatric Interview” of the DSM-IV. Depressive symptoms were evaluated using the “Beck Depression Inventory” (BDI).ResultsThe average age was 39 years. The sex ratio M/F was 1/2.The GAD was diagnosed in 10.8% of participants. The mean IDB score was 3.8. According to this scale, a mild depression was noted in 23.6%, moderate 12% and severe in 2.8% of cases. The GAD was statistically associated with psychiatric histories (P = 0.009), particularly depression disorder (P = 0.004) and the history of suicide attempt (P < 0.001).The IDB score was significantly higher in participants with GAD (P < 0.001). Among them, 74% presented moderate to severe depression.GAD co-occurs with PD in 22.2% of cases. This association was statistically significant (P < 0.001). Participants presenting GAD- PD comorbidity are at higher risk of developing depression (P = 0.003).ConclusionOne must always think to screen comorbidities in the presence of either diagnosis, in order to ensure a better management.Disclosure of interestThe authors have not supplied their declaration of competing interest.

scholarly journals Assessment of severity, quality of life and suicidal ideation in patients with depressive disorders

2020 ◽  
Vol 11 (4) ◽  
pp. 7151-7159
Author(s):  
Imran Mansur M D ◽  
Shreeharsha G ◽  
Akshay C ◽  
Ravi Chandra C V ◽  
Binai K Sankar ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Suicidal Ideation ◽  
Depressive Disorders ◽  
Rating Scale ◽  
Severe Depression ◽  
Physical And Mental Health ◽  
Mild Depression ◽  
Increased Risk ◽  
Study Population

Depression is estimated to be the third leading cause of disability and about 350 million people suffer from depression worldwide. Various biological, social, economic, cultural factors and environmental factors contribute for depression. A total of 102 patients were enrolled in the study. Majority of the patients (64, 62.74%) included in the study were female. The mean age of the study subjects was found to be 20.4±11.88 years. The severity of symptoms in depressed patients evaluated using Hamilton Depression Rating Scale (HDRS) shows that 33.33% of the subjects were very severely depressed, followed by 29.41% of the subjects with moderate depression, 23.52 % with severe depression and 11.76% with mild depression. Quality of life was evaluated using WHOQOL BREF Scale in the study population. 51.96 % of subjects were having low quality of life (QoL) followed by 48% of subjects with medium QoL and 0.98% subjects with high QoL. Modified Scale for Suicidal Ideation (MSSI) was used to evaluate severity of suicidal ideation in study population. Interpretation of results shows that 74.50% were having low suicidal ideation and few subjects (8.82%) were found to have severe suicidal ideation. Depression negatively impacts individual’s functioning, work satisfaction, relationships, leisure, physical and mental health, sexual functioning, sleep patterns and overall sense of fulfilment and contentment with life. Severe form of depression can lead to suicidal risk, increased risk of morbidity, mortality, substantial imbalance on individual’s occupational potential,  significant physical and psychosocial impairment.

The Subjective Perception of Time as a Factor of the Course of Depressive Disorders

2017 ◽  
Vol 41 (S1) ◽  
pp. S143-S143
Author(s):  
V. Fedchenko ◽  
T. Panko ◽  
G. Kalenska
Keyword(s):  
Depressive Disorders ◽  
Severe Depression ◽  
Integrated Approach ◽  
Present Condition ◽  
Subjective Perception ◽  
Moderate Degree ◽  
Mild Depression ◽  
The Past ◽  
The Future ◽  
Depressive Episodes

IntroductionPersonal peculiarities of the individual are the separate significant factor of formation and course of depression that has a predictive value.ObjectivesInvestigation of an emotionally significant attitude of patients to their past, present, future and also depending on the severity of depressive symptoms.MethodologyForty patients with depressive episodes (F 32.0. F 32.1, F 32.2) and 35 persons without mental disorders were examined. An integrated approach was applied using the method of “Semantic time differential”.ResultsCorrelation analysis showed that in mild depression patients experienced their present condition changed, it is associated with emotional assessment of the past (r = −0.441) and extrapolated their experiences for the future–feeling doubt about their implementation in the future, including its activity (r = −0.484) and size (r = −0.523). In an moderate degree of depression patients in the present acutely realized that they had depression and from the point of view of this condition perceived their past and future–feeling a structureness and size of the past (r = 0.500) and worrying about the emotional background, structureness and activity of the future (r = −0.500. r = −0.756 and r = −0.500. respectively). In severe depression patients did not associate their condition with the past, realized the presence of depression in the present, and did not expected to improve their emotional conditions in the future (r = −0.432).ConclusionsThe data can be used to assess the dynamics of patient's conditions with depressive episodes as well as to develop an adequate psychotherapy.

Pterin metabolism in depression: an extension of the amine hypothesis and possible marker of response to ECT

1992 ◽  
Vol 22 (4) ◽  
pp. 863-869 ◽  
Author(s):  
David N. Anderson ◽  
Mohammed T. Abou-Saleh ◽  
James Collins ◽  
Kevin Hughes ◽  
Richard J. Cattell ◽  
...  
Keyword(s):  
Urinary Excretion ◽  
Electroconvulsive Therapy ◽  
Depressive Disorders ◽  
Therapeutic Response ◽  
Severe Depression ◽  
Psychotic Depression ◽  
Before And After ◽  
Healthy Control ◽  
Depressive Subtypes ◽  
Rate Limiting

SynopsisUrinary excretion of neopterins and biopterins was measured in 23 patients with severe depression before and after receiving electroconvulsive therapy (ECT) and 26 healthy control subjects. Patients with psychotic depression and those responding to ECT had neopterin:biopterin (N:B) ratio significantly higher than controls before commencing ECT and positive therapeutic response was associated with reduction of N:B ratio towards control values. As a raised N:B ratio implies failure to convert neopterin to biopterin it is possible that reduced availability of tetrahydrobiopterin, the essential cofactor for the formation of noradrenaline, serotonin and dopamine, may exert rate limiting control over the synthesis of monoamines implicated in the pathogenesis of depressive disorders. The N:B ratio may be a marker for certain depressive subtypes and response to ECT.

scholarly journals Depression among infertile women in Gaza strip: Prevalence and correlates

2020 ◽  
Author(s):  
Aymen Elsous ◽  
Sae'd Abu El-Kass ◽  
Akram Salama ◽  
Mahmoud Radwan ◽  
Soha Abo Eid ◽  
...  
Keyword(s):  
Psychological Intervention ◽  
Gaza Strip ◽  
Severe Depression ◽  
Wald Test ◽  
Simple Random Sampling ◽  
Mild Depression ◽  
Cross Sectional ◽  
Vitro Fertilization ◽  
Infertile Women

Abstract Background Psychological disorders are expected for women suffering from infertility. Depression is a predictable consequence and requires more investigations and considerations. This study aimed to determine prevalence and severity of depression and its predictors among infertile women in Gaza strip, Palestine using a cross-sectional design. Methods A cross sectional study was carried out among three hundred eighty five infertile males from Jan 2019 to Dec 2019. Participants were selected from three main In-vitro fertilization centers (IVFs) following simple random sampling. The Arabic version of Beck depression inventory was used. Logistic regression was performed to determine independent factors associated with depression. The value 0.05 or less was considered statistically significant Results The mean age of participated women was 29 ± 6.58 years, and mean duration of marriage and infertility were 7.76 ± 5.31 and 5.43 ± 3.50 years, respectively. Half of women had some form of depression (22.3%, 8.6% and 10.6% showed to have mild depression, moderate and severe depression, respectively). Predictors of depression were: duration of marriage (Wald test: 10.493; CI95%: 0.248–0.774), at least one abortion (Wald test: 21.233, CI95%: 1.863–4.528), primary infertility (Wald test: 6.666, CI95%: 1.148–2.742) and husband cause of infertility (Wald test: 10.878, CI95%: 0.800–0.982). Conclusion Infertility has an effect on the psychological aspect of women' life. Psychological intervention including counselling, support and therapy would be necessary to limit consequences of infertility. Such interventions could be implemented in infertility treatment clinics.

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