scholarly journals Low neutrophil-to-lmphocyte ratio decreases risk of coronavirus disease in pregnant women

Author(s):  
Nutria Widya Purna Anggraini ◽  
Sri Sulistyowati

<div class="WordSection1">BACKGROUND<br />Coronavirus Infection 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is an emergency condition for global public health. Early detection of COVID-19 in pregnant women is needed. The neutrophil-to-lymphocyte ratio (NLR), as a marker of viral inflammatory response, is used to determine the presence of a viral or bacterial infection, both acute and chronic. The objective of this study was to determine the relationship between NLR and the polymerase chain reaction (PCR) swab test results in pregnant women with suspected coronavirus disease 2019.<br /><br />METHODS<br />A cross-sectional study was conducted on 9 pregnant women with suspected COVID-19. The subjects were inpatients at Moewardi Hospital Surakarta from 19 April-19 May 2020, who had rapid tests, complete blood examinations, and PCR swab tests. The NLR was categorized based on early warning scores according to research developed at Zhejiang University, with cut-off point 5.8. Diagnosis of COVID-19 was confirmed by PCR swab tests. Relation between NLR   and PCR swab results was analyzed by the prevalence ratio.<br /><br />RESULTS<br />Two patients (22.2%) had NLR &gt;5.8, with positive swab results in both (100%). Seven patients with NLR &lt;5.8 had positive swabs in only one (33.3%). The relationship between NLR and PCR swab test results showed a prevalence ratio of 0.143 (95% CI 0.023-0.877).<br /><br />CONCLUSION<br />Pregnant women with NLR &lt; 5.8 had a decreased risk of COVID-19. Routine blood examination is more suitable for finding pregnant women with suspected COVID-19.</div>

2019 ◽  
Vol 6 (2) ◽  
pp. 126-129
Author(s):  
Dhandi Wijaya ◽  
Nur Adiba Hanum ◽  
Asih Handayani

Increased levels of the hormones estrogen and progesterone in the blood during pregnancy can cause gingivitis due to vascular changes that cause the gingiva to become more sensitive especially to toxins and other irritants, such as plaques and calculus, which causes the gingiva to become easily inflamed. Pregnancy can also aggravate gingivitis due to the excessive inflammatory response of the gingiva to dental plaque and hormonal changes that occur during pregnancy. This study aims to determine the differences in the degree of gingivitis in pregnant women in each trimester of gestational age. This study was a cross-sectional study conducted in April 2019 on 80 pregnant women with gingivitis who examined their pregnancies at the Puskesmas Merdeka Palembang during the fourth week of March 2019. The relationship between the degree of gingivitis in each trimester of pregnancy was analyzed using Fisher's exact test with 95% confidence interval. The results showed that gingivitis was found most frequently in third trimester pregnancy (47.5%) and mild gingivitis, mostly experienced by pregnant women in trimester II pregnancy (52.6%), while moderate and severe gingivitis was more experienced by trimester pregnant women III (50% and 81.8%). The statistical test results showed a significant relationship between the gestational age and severity of gingivitis (p 0.05). It can be concluded that increasing gestational age is related to the increasing severity of gingivitis.


Author(s):  
Dyah Widiastuti ◽  
Dwi Priyanto

Leptospirosis is associated with occupations which exposed workers to contaminated environments. The risk of leptospirosis exposure in the market as a gathering place for many people needs to be assessed, to obtain the basis for decision making to anticipate leptospirosis transmission. This study aimed to determine the relationship between market environmental conditions including market sanitation conditions, the level of rat density and the presence of leptospira-positive rats  toward the history of leptospirosis exposure among market workers (traders and janitors). A cross sectional study conducted in 35 markets in Banjarnegara and 175 market workers randomly selected. Blood samples analysed using ELISA against 40 Kda pathogenic Leptospira protein. Rat trapping  conducted in each market for two days with 100 traps. The caught mice examined with Polymerase Chain Reaction (PCR) to detect the presence of Leptospira bacteria in their kidneys. Leptospirosis exposure was spread in 17 markets in Banjarnegara. The PCR examination showed that the pathogenic Leptospira infected rats were spread in four markets in Banjarnegara. Chi square test showed that the hygene condition in market area was significantly associated with the leptospirosis exposure. Markets workers (traders and janitors) were at risk for leptospirosis proved by high seroprevalence of leptospirosis in this study.


2021 ◽  
Vol 8 (2) ◽  
pp. 14-18
Author(s):  
Rabeea Sadaf ◽  
Muhammed Zahid ◽  
Nasreen Kishwar ◽  
Umaiyma Farhad ◽  
Behzad Khan Khalil

OBJECTIVES: The study aimed to determine the frequency of COVID-19 positive antenatal patients admitted in Obstetrics & Gynecology unit Hayatabad Medical Complex Peshawar with the concerns that pregnant women may be more susceptible to COVID-19 as they may be more vulnerable to respiratory infection. METHODOLOGY: This was a descriptive cross-sectional study conducted at Obstetrics & Gynecology units Hayatabad Medical Complex Peshawar from May 12th, 2020, to November 29th, 2020, screening and testing of patients admitted for childbirth was in HMC. Screening consisted of questions related to travel, contacts, and symptoms of COVID-19. All patients without a prior diagnosis of COVID-19 underwent SARS-CoV-2 polymerase chain reaction (PCR) testing of nasopharyngeal swabs, with rapid testing available. Patients scheduled for cesarean birth were screened and tested at preoperative visits RESULTS:  One hundred eighty-two patients presenting for antenatal visits were screened; 6.5% (12 out of 182) were previously diagnosed with COVID-19. The remaining 170 patients were tested at admission, and 17.6% (30 out of 170) tested positive for SARS-CoV-2. Twenty-two of the 30 who tested positive for SARS-CoV-2 (73.3%) were asymptomatic. The overall prevalence of positive test results among asymptomatic patients was 14.1% (22 out of 156). The prevalence of positive test results among asymptomatic patients increased from 1.29% (2 out of 155). CONCLUSION: The evidence on this novel infection is changing almost daily, although it will likely be many months before, we can determine the true impact it will have on both maternal and fetal well‐being. In the interim, our primary responsibility is to ensure all women have access to safe maternity services. KEYWORDS: Asymptomatic, COVID-19 Positive, Antenatal Patients, Obstetrics & Gynecology, Infection


2017 ◽  
Vol 55 (1) ◽  
pp. 14-18 ◽  
Author(s):  
Monavar Gilanifar ◽  
Moloud Aghajani Delavar

Abstract Introduction. Alexithymia is related to poor emotion regulation strategies as well as higher rates of somatic disorders. The aim of the present study was to assess the relationship between alexithymia and the general symptoms experienced by the pregnant women. Material and Methods. In a cross-sectional study, a total number of 350 pregnant women, attending the antenatal clinics, were randomly selected. A standardized Toronto Alexithymia Scale (TAS-20) was used to elicit responses from participants with alexithymia. The general symptoms scores were measured using the Iranian version of the Symptom Checklist-90-Revised, 90 items. The statistical associations between alexithymia and the general symptoms were then investigated through liner regression. Results. A total number of 186 of pregnant women with alexithymia were compared with the 164 cases without alexithymia. The high scores on Total Toronto Alexithymia Scale-20 and the difficulties to identify feelings emerged as major predictors for the current psychopathology on all SCL-90-R subscales. The difficulty in describing feelings features of alexithymia is positively associated with interpersonal sensitivity and paranoid ideation, but it is inversely associated with the phobic anxiety dimension. Conclusion. This study showed that the pregnant women with difficulty in describing feelings features of alexithymia are likely to show a broad range of psychopathology. Therefore, it is necessary to emphasize the benefits of specific psychotherapeutic techniques to improve self-differentiation so that we can reduce the likelihood of mental illnesses in pregnant women.


2019 ◽  
Vol 35 (5) ◽  
Author(s):  
Resmiye Özdilek ◽  
Yılda Arzu Aba ◽  
Sena Dilek Aksoy ◽  
Bulat Aytek Şık ◽  
Yaşam Kemal Akpak

Objective: To investigate the adaptation of pregnant women to the recommended weight gain range according to body mass index (BMI) and to determine the factors affecting them. Methods: This cross-sectional study was performed in a university hospital’s obstetrics and gynecology unit (tertiary center) in Turkey. This study was conducted between March 2018 and August 2018 (6 months) in pregnant women. Pregnant women with chronic disease and receiving treatment during antenatal follow-up, with twin pregnancy, with a fetus with a congenital abnormality, and nutritional disturbance were excluded from the study. Eight hundred twelve pregnant women with normal antenatal follow-up and who volunteered to participate were included in the study. Results: The mean age of the participants was 27.66±5.05 years. The mean weight and BMI before pregnancy were near standard in all participants. The group with the highest rate of recommended weight gain according to BMI before pregnancy was the group with low weight pregnant women. The ideal weight gain rate in all groups was 32%. Conclusions: The groups with overweight and obese pregnant women according to BMI before pregnancy had the highest rates of weight gain, above the recommended limits. BMI before pregnancy directly affects weight gain during pregnancy and the importance of pre-pregnancy counseling and weight loss is emphasized once again. doi: https://doi.org/10.12669/pjms.35.5.133 How to cite this:Ozdilek R, Aba YA, Aksoy SD, Sik BA, Akpak YK. The relationship between body mass index before pregnancy and the amount of weight that should be gained during pregnancy: A cross-sectional study. Pak J Med Sci. 2019;35(5):---------.  doi: https://doi.org/10.12669/pjms.35.5.133 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


2018 ◽  
Vol 2 (1) ◽  
pp. 21-25
Author(s):  
Mayuliani Mayuliani ◽  
Dovy Djanas

Objective :To find out the relationship between the duration of MgS04 administration in severe preeclampsia patients and eclampsia with the incidence of hypermagnesium.Method :This study is a comparative observational study using a cross sectional study design. The study was conducted in the medical record of Dr.M.Djamil Padang Hospital during the period January 1, 2016 to August 31, 2017 of pregnant women with severe preeclampsia and eclampsia, found 30 study subjects who met the inclusion criteria. Furthermore, data is recorded in a research form that has been provided, then carried out research data processing. Statistical analysis to assess significance using the chi-square test.Results : Magnesium levels increased in pregnant women with severe preeclampsia and eclampsia by 21 correspondents. Increased Magnesium levels in patients with severe preeclampsia and eclampsia who received MgS04 treatment for 48 hours by 16 correspondents (84.2%) and 5 correspondents with MgS04 administration for 24 hours.Conclusion : There is a significant relationship between the duration of Magnesium Sulfate with the incidence of hyperpermagnesium in patients with severe preeclampsia and eclampsia. Keywords: severe preeclampsia, eclampsia, magnesium sulfate, magnesium levels


2021 ◽  
Vol 12 (2) ◽  
pp. 156
Author(s):  
Nurmela Setia Ningsih ◽  
Betty Yosephin Simanjuntak ◽  
Miratul Haya

<p>Pregnant women are one of the vulnerable groups. During pregnancy, there is an increase in the need for nutrients to meet the needs of the mother and fetus as well as preparation for labor. It is very important to pay attention to the recommended weight gain during pregnancy to prevent the occurrence of low birth weight. The purpose of this study was to determine the relationship between energy, carbohydrate, fat, and protein intake on weight gain of pregnant women in the city of Bengkulu. The design of this study was a cross-sectional study with a total sample of 47 pregnant women who had received an education of the first thousand days of life when registering to become a prospective bride at the Religious Affairs Office. As many as 53.2% of mothers had good weight gain and had a relationship between energy intake (p-value 0,032), carbohydrate intake (p-value 0,024), protein intake (p-value 0,039), and fat intake (p-value 0,023). Energy and macronutrients have a relationship with the weight gain of pregnant women in the group of preconception couples who have received education about the first 1000 days of life. It is hoped that pregnant women will be able to control their weight during pregnancy and apply the knowledge that has been obtained through education while preconception age.<strong></strong></p>


2020 ◽  
Vol 1 (1) ◽  
pp. 1-4
Author(s):  
Rabiatul Udawiyah ◽  
Lely Setyawati ◽  
Cokorda Bagus Jaya Lesmana

Background: Emotional and behavioral problem are persistent and recurring problem that observed in teenagers specifically students. Anxiety is the most common mental health problem found in Islamic boarding school students. This research aims to find out the relationship of anxiety with emotional and behavioral problem in Madrasah Tsanawiyah, Hidayatullah Islamic Boarding School Students, Denpasar. Patients and Methods: The study was an analytical cross-sectional study with 89 students met inclusion and exclusion criteria. This research used the Strength and Difficulties Questionnaire (SDQ) to measure emotional and behavioral problems and Beck Anxiety Inventory (BAI) to measure the student’s anxiety level. The correlation was analyzed by using Spearman’s correlation test. Results: Forty-five (50.8%) students experience abnormal emotional and behavioral problems with 30 (30%) the students mostly had moderate level anxiety. The correlation between the anxiety with emotional and behavioral problems had an R value of 0.366 (p<0.001). Conclusion: There was a moderate positive relationship between anxiety with emotional and behavioral problems in Madrasah Tsanawiyah Islamic boarding school Hidayatullah students.


Author(s):  
Anasril Anasril ◽  
Muhammad Husaini ◽  
Bustami Bustami ◽  
Amiruddin Amiruddin

Stimulation of growth and development, especially language development in children, needs to be done to improve children's ability to speak in accordance with the level of development. The lack of information obtained by mothers about the importance of language stimulation for children causes mothers to consider it normal when a child is able to speak too late. The purpose of this study was to determine the relationship between maternal knowledge and the level of language development in children aged 2-3 years in Puskesmas Pandang Panyang, Nagan Raya. This research is analytical with a cross-sectional study design. The number of samples is 100 people taken randomly. The results showed that there was a significant relationship between maternal knowledge about language stimulation and language development in children aged 2-3 years with a value of p = 0.000. With Prevalence ratio (PR), namely 31.89. It is recommended that parents increase their knowledge of language stimulation in order to realize language development according to age and child


Author(s):  
Dewanto Khrisnamurti

Objective: To detect malaria by PCR examination of saliva in pregnant women and to obtain the incidence of malaria and the type of plasmodium causing malaria in pregnant women at various hospital in North Sulawesi. Method: A descriptive cross sectional study in pregnant women during antenatal care at the Department of Obstetrics and Gynecology Faculty of Medicine University of Sam Ratulangi/Prof. Dr. R.D. Kandou General Hospital in Manado, R.W. Monginsidi Hospital in Manado, Bethesda Hospital in Tomohon, and Datoe Binangkang Hospital in Kotamobagu, from 1 April until 31 May 2008. Result: There were 43 pregnant women clinically diagnosed with malaria, 23 (53.49%) by PCR examination of saliva and 20 (46.59%) by blood smears. From 23 cases of malaria in pregnancy detected by PCR, there were 18 diagnosed as tropical malaria, 3 tertian malaria, and 2 mixed malaria. Conclusions: The incidence of malaria in pregnancy at various hospital in North Sulawesi using PCR methods for saliva examination from April 1 - May 31 2008 is 53.49%. In this study malaria are mostly caused by Plasmodium falciparum with the largest incidence in primigravida, in the first trimester. [Indones J Obstet Gynecol 2012; 36-1:14-9] Keywords: malaria, PCR, pregnancy, saliva


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