scholarly journals Sexual dimorphism in stapes by discriminant functional analysis

Author(s):  
Kamal Singh ◽  
Aarti Rohilla

Background: Sexing of human skeleton is highly contested subject and is usually done by using morphological and metrical traits of big intact bones like skull, mandible, pelvis and long bones etc.1 The stapes remains well protected by being housed in the middle ear, even in the mutilated bodies.Methods: The morphometric study of the 120 human stapes bones from 60 unidentified cadavers was aimed to know the presence of sexual dimorphism.Results: The weight and measurements of footplate could be a good criterion for determining percentage accuracy as male and female respectively and could be used as a potential tool for determination of sex.Conclusions: The study of normal dimensions and indices of stapes will provide insight to the forensic experts for deciding the sex of an individual in the disputed cases. Our findings are the results for guidance and future manipulation in the forensic and legal medicine.

2014 ◽  
Vol 2014 ◽  
pp. 1-5 ◽  
Author(s):  
C. N. Orish ◽  
B. C. Didia ◽  
H. B. Fawehinmi

Background. Determination of sex is an important concern to the forensic anthropologists as it is critical for individual identification. This study has investigated the existence of sexual dimorphism in the dimensions and the area of the IOA triangle. Methods. A total of 100 adult dry skulls, (78 males; 22 females) from departments of anatomy in Nigerian universities were used for this study. Automatic digital calliper was used for the measurement. Coefficient of variation, correlation, linear regression, percentiles, and sexual dimorphism ratio were computed from the IOA triangle measurements. The IOA triangle area was compared between sexes. Results. The male parameters were significantly (P<0.05) higher than female parameters. The left opistocranium-asterion length was 71.09±0.56 and 61.68±3.35 mm and the right opistocranium-asterion length was 69.73±0.49 and 60.92±2.10 mm for male and female, respectively. A total area of IOA triangle of 1938.88 mm2 and 1305.68 mm2 for male and female, respectively, was calculated. The left IOA indices were 46.42% and 37.40% in males and females, respectively, while the right IOA indices for males and females were 47.19% and 38.87%, respectively. Conclusion. The anthropometry of inion-opistocranium-asterion IOA triangle can be a guide in gender determination of unknown individuals.


Author(s):  
Kanchan Bisht ◽  
Rakesh K. Verma ◽  
Archana Rani ◽  
Navneet Kumar ◽  
Baibhav Bhandari

Introduction: For the assessment of sexual dimorphism of human skeleton, pelvis has been used with great accuracy by anthropologists and forensic experts. Sacrum, being an integral part of pelvis, has therefore gained importance. Among the various parameters of sacrum, sacral index is the most reliable one, calculated by the formula: Sacral index=max breadth x100/max length of sacrum. This study aimed to determine the significance of sacral index in estimation of sex in north Indian population. Materials and methods: For the present study, 35 dry human sacrum bones were obtained from the Department of Anatomy, KGMU, Lucknow, out of which 32, free of deformity, were used in study. The bones were first separated as male and female on the basis of their gross features. Maximum length and breadth of sacra were measured using digital sliding Vernier calliper and sacral index was calculated. Results: Mean sacral index was significantly higher in females (109.52) as compared to males (92.37). Sex determination done on the basis of gross features were comparable to that done by calculation of sacral index, except in sacrum no. 5,13,14,15 &16. Sacrum no. 5,13,14 &15 were more curved forwards (female feature) while their sacral indices were much lesser (male feature). Sacrum no. 16 had a uniform curvature (male feature) while its sacral index was>105 (female feature). Sacrum no. 16 also had only 3 dorsal and ventral foramina, which was a variation. Conclusions: Sacral index is a reliable criterion for sex determination, useful for anatomical, medicolegal and anthropological purposes.


2021 ◽  
Vol 10 (33) ◽  
pp. 2765-2768
Author(s):  
Rajeev Kumar Kanchan ◽  
Sonali Subhadarsini ◽  
Dharma Niranjan Mishra ◽  
Chinmayi Mohapatra

BACKGROUND Femur is the longest and strongest bone of the human body. It also takes relatively longer time to disintegrate after death, hence morphometric analysis of skeletal remains of femoral head can be considered for the determination of age and sex for forensic expert, anthropologist as well as anatomist. The present study was an attempt to establish sex of a skeleton by the help of femoral head diameters which will be of great help in medico-legal and anthropometric studies. METHODS The present study was carried out in the S C B Medical College Cuttack from May 2019 to June 2020 by taking 84 dried and intact femora. The vertical head diameter of femoral head and head circumference were measured by the vernier’ s caliper and measuring tape in centimeters. RESULTS The result showed significant difference in the head circumference and the vertical diameter of head of femur of the male and female femora. It was found that the mean femoral head circumference of the male was 13.296 cm with a “S.D” of 0.8694 cm and female was 12.023 cm with a “S.D” of 0.73 cm and vertical diameter of male was 4.1520 cm with a “SD” of 0.3635 cm and that of female femora was 3.7231 cm with a “S.D” of 0.2264 cm respectively. CONCLUSIONS There was a significant difference in the head circumference and the vertical diameter of head of femur of the male and female femora which determines sexual dimorphism. KEY WORDS Anthropometry, Medico-Legal, and Standard Deviation (SD)


2015 ◽  
Vol 12 (1) ◽  
pp. 17-21
Author(s):  
AHM Mostafa Kamal ◽  
Shamim Ara ◽  
Shahanaz Begum ◽  
Md Mesbahul Hoque ◽  
Khadeza Khatun

Context : It has long been customary among anatomists, anthropologists and forensic experts to judge the sex of the skeletal material by non-metric observations. Afterward the study of sexual divergence has been based upon actual measurements in different bones. The study in relation to metrical data on bone is very few in our country. The study was planned to observe the differences of sacra between male and female in respect to measurement of alar length and auricular index of sacrum. The findings of this study might be useful in providing morphometrical data that can be used by anatomists, forensic experts, anthropologists, orthopedic surgeons and neurologists for proper initiative in their respective fields. Materials and Methods: A cross-sectional, analytical type of study was performed in the department of Anatomy, Dhaka Medical College, Dhaka from January 2011 to December 2011. A total of 172 (one hundred seventy two) adult human dry sacra of unknown sex was assessed. The study samples were distributed in male and female sex groups by discriminant function analysis. All the samples were studied morphologically. Length of ala and auricular surface were measured with the help of digital slide calipers. Results: The mean length value of ala was greater in female than male (P<0.001). The difference between the mean value of alar index in male and female was significant (P >0.05). The mean value of auricular index was higher in male than female and the difference was statically significant (P<0.001). Conclusion: The sacrum can be used for sexual dimorphism as is usual in anthropological work. The knowledge of alar length and auricular index of sacrum is essential in medico-legal practice for sex determination of an individual. DOI: http://dx.doi.org/10.3329/bja.v12i1.22613 Bangladesh Journal of Anatomy, January 2014, Vol. 12 No. 1 pp 17-21


2020 ◽  
Vol 25 (2) ◽  
pp. 121-126
Author(s):  
V. G. Galonsky ◽  
N. V. Tarasova ◽  
V. V. Aliamovskii ◽  
I. S. Leonovich

Relevance. Separate issues in anthropomorphic sizes of relative norm of the ideal smile, its qualitative and qualitative parameters have not been addressed to sufficiently and are not properly reflected in scientific literature.Purpose. To determine distinguishing features in average smile parameters of the smile in male and female patients with orthognathic occlusion.Materials and methods. A clinical and anthropometric evaluation of parameters in main smile types was carried out for 150 young males and 150 young females aged 19-24 who had identical physiological development parameters.Results. It has been revealed that occurrence frequency of main smile types in patients with orthognathic occlusion has pronounced signs of sexual dimorphism which in over one half of the cases lies in predominance of the incisal smile type in males (52.7%) and the fascial type in females (55.3%). Occurence frequency of the cervical smile type totaled 25% among the studied patients of both genders. Average vertical size parameters in the incisal smile lies within the diapason of 3.91-4.91mm with surpassing by 1mm in males. Analogical data for the fascial smile type form the diapason of 6.21-6.73mm with surpassing by 0.52mm in females. The cervical smile type is characterised by larger vertical size forming the diapason of 7.94-8.91mm with surpassing by 0.97mm in males.Conclusion. The results of the study have shown that the “beautiful and ideal smile” is a relative concept having varied anthropometric characteristics and pronounced signs of sexual dimorphism lying in a broad spectrum of the dentofacial system norm notion with specific vectors for individual morphological deviations.


Genetics ◽  
2003 ◽  
Vol 165 (3) ◽  
pp. 1167-1181
Author(s):  
Pei-Wen Chiang ◽  
David M Kurnit

Abstract Using a sensitive RT-QPCR assay, we analyzed the regulatory effects of sex and different dosage compensation mutations in Drosophila. To validate the assay, we showed that regulation for several genes indeed varied with the number of functional copies of that gene. We then confirmed that dosage compensation occurred for most genes we examined in male and female flies. Finally, we examined the effects on regulation of several genes in the MSL pathway, presumed to be involved in sex-dependent determination of regulation. Rather than seeing global alterations of either X chromosomal or autosomal genes, regulation of genes on either the X chromosome or the autosomes could be elevated, depressed, or unaltered between sexes in unpredictable ways for the various MSL mutations. Relative dosage for a given gene between the sexes could vary at different developmental times. Autosomal genes often showed deranged regulatory levels, indicating they were in pathways perturbed by X chromosomal changes. As exemplified by the BR-C locus and its dependent Sgs genes, multiple genes in a given pathway could exhibit coordinate regulatory modulation. The variegated pattern shown for expression of both X chromosomal and autosomal loci underscores the complexity of gene expression so that the phenotype of MSL mutations does not reflect only simple perturbations of genes on the X chromosome.


Molecules ◽  
2021 ◽  
Vol 26 (13) ◽  
pp. 3983
Author(s):  
Ozren Gamulin ◽  
Marko Škrabić ◽  
Kristina Serec ◽  
Matej Par ◽  
Marija Baković ◽  
...  

Gender determination of the human remains can be very challenging, especially in the case of incomplete ones. Herein, we report a proof-of-concept experiment where the possibility of gender recognition using Raman spectroscopy of teeth is investigated. Raman spectra were recorded from male and female molars and premolars on two distinct sites, tooth apex and anatomical neck. Recorded spectra were sorted into suitable datasets and initially analyzed with principal component analysis, which showed a distinction between spectra of male and female teeth. Then, reduced datasets with scores of the first 20 principal components were formed and two classification algorithms, support vector machine and artificial neural networks, were applied to form classification models for gender recognition. The obtained results showed that gender recognition with Raman spectra of teeth is possible but strongly depends both on the tooth type and spectrum recording site. The difference in classification accuracy between different tooth types and recording sites are discussed in terms of the molecular structure difference caused by the influence of masticatory loading or gender-dependent life events.


Author(s):  
Luise Hochmuth ◽  
Christiane Körner ◽  
Fritzi Ott ◽  
Daniela Volke ◽  
Kaja Blagotinšek Cokan ◽  
...  

AbstractThe liver is one of the most sexually dimorphic organs. The hepatic metabolic pathways that are subject to sexual dimorphism include xenobiotic, amino acid and lipid metabolism. Non-alcoholic fatty liver disease and hepatocellular carcinoma are among diseases with sex-dependent prevalence, progression and outcome. Although male and female livers differ in their abilities to metabolize foreign compounds, including drugs, sex-dependent treatment and pharmacological dynamics are rarely applied in all relevant cases. Therefore, it is important to consider hepatic sexual dimorphism when developing new treatment strategies and to understand the underlying mechanisms in model systems. We isolated primary hepatocytes from male and female C57BL6/N mice and examined the sex-dependent transcriptome, proteome and extracellular metabolome parameters in the course of culturing them for 96 h. The sex-specific gene expression of the general xenobiotic pathway altered and the female-specific expression of Cyp2b13 and Cyp2b9 was significantly reduced during culture. Sex-dependent differences of several signaling pathways increased, including genes related to serotonin and melatonin degradation. Furthermore, the ratios of male and female gene expression were inversed for other pathways, such as amino acid degradation, beta-oxidation, androgen signaling and hepatic steatosis. Because the primary hepatocytes were cultivated without the influence of known regulators of sexual dimorphism, these results suggest currently unknown modulatory mechanisms of sexual dimorphism in vitro. The large sex-dependent differences in the regulation and dynamics of drug metabolism observed during cultivation can have an immense influence on the evaluation of pharmacodynamic processes when conducting initial preclinical trials to investigate potential new drugs.


Author(s):  
Magaji Garba Taura ◽  
Lawan Hassan Adamu ◽  
Abdullahi Yusuf Asuku ◽  
Kabiru Bilkisu Umar ◽  
Musa Abubakar

Abstract Background Sex determination is one of the leading criterion in identification and verification of an individual. However, the potential roles of differences in adjacent fingerprint white line count (FWLC) in sex inference are not well elucidated in the literature especially among Hausa population. The study was conducted to determine sexual dimorphism and predict sex using adjacent digit FWLC difference (adj. DFWLCD) among Hausa population of Kano state, Nigeria. Methods The study population involved 300 participants. FWLC was determined from a plain fingerprint captured using live scanner. The formula for adj. DFWLCD of thumb and fifth digit is dR15 for right hand. The same applied for possible combination in cephalocaudal direction. Mann-Whitney and t tests were used for comparison of variables between sexes. Binary logistic regression analyses were employed for determination of sex. Results We observed a significantly larger adj. DFWLCD in males compared with females in most of the digit combination. A significant sexual dimorphism was observed in most of the adj. DFWLCD involving ring digit in both right (dR14, dR24, and dR34) and left (dL14, dL24, and dL34). The best discrimination was observed in adjacent FWLC difference of second and fourth digits in both right and left digits (dR24 and dL24). This was further supported by stepwise logistic regression analyses. Conclusion The adj. DFWLCD exhibits sexual dimorphism. The best prediction potentials were found to be dR24 and dL24 for right and left hands respectively.


1965 ◽  
Vol 20 (4) ◽  
pp. 318-322 ◽  
Author(s):  
Irmgard Ziegler ◽  
M. Feron

In the eyes of male and female flies a quantitative determination of the tetrahydropterin, the corresponding dihydro-compound (Sepiapterin) and of xanthommatin from 0—5 days after hatching was made. The increase of xanthommatin almost stops 24 hours after hatching; about 13 μg are present after that time. The tetrahydropterin, after a drastic increase during the first 24 hours, remains at a level of about 1,1 — 1,2 µg. In contrast the dihydrocompound which is nearly absent at the time of hatching is deposited on the eye-granules between the third and fifth day. At that time, especially in the male the dihydropterin/tetrahydropterin ratio is increased. Starvation during the first 24 hours has essentially no effect on the amount of xanthommation whereas the amount of pterins is markedly reduced.


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