scholarly journals Calcium levels and metabolic disturbance in renal disease patients receiving hemodialysis: a cross sectional study highlighting its association in dialysis patients

Author(s):  
Wajeeha Elahi ◽  
Ameen Zubair Syed ◽  
Bilal Jamil ◽  
Madiha Arif ◽  
Nazia Qamar ◽  
...  

Background: The aim of this study was to determine the disturbances in Calcium and other mineral levels in patients on hemodialysis at Tabba Kidney Institute, Karachi, Sindh, Pakistan.Methods: A cross sectional observational study through convenient sampling technique was conducted from January 2017 to August 2017 at Tabba Kidney Institute, Karachi after obtaining ethical approval. 255 patients, all above 18 years of age and on hemodialysis were included in the study. Multi-organ failure patients on dialysis, other systemic diseased patients on hemodialysis were excluded. Demographic variables, mineral levels, symptoms and supplementations were recorded. SPSS version 20.0 was used for data analysis.Results: A total of 255 patients on hemodialysis were selected and divided into groups depending upon median years of hemodialysis below and above 5 years of hemodialysis. Median and IQR of calcium were 8.8 and 8.2-9.1 mg/dl for below 5 years, 8.6 and 8.1-9.1 mg/dl for above 5 years (P value=0.44). Median and IQR of phosphate were 4.9 and 3.9-5.7 mg/dl for below 5 years and 4.6 and 3.7-5.5 mg/dl for above 5 years (P value=0.21). Median and IQR of parathyroid hormone were 393 and 212-699 pg/ml for below 5 years and 329 and 128-657 pg/ml for above 5 years. (P value=0.13) Median and IQR of albumin were 4.0 and 3.6-4.2 mg/dl for below 5 years and 4.0 and 3.8-4.3 for above 5 years (P value=0.30). Total of 18 (10.9%) had para thyroidectomy.Conclusions: Present study showed that significant difference in mineral levels did not exist in patients on hemodialysis as regards to the duration of dialysis. However clinical features had a tendency to decrease as duration of dialysis increased to above 5 years. Para thyroidectomy and itching were two main significant findings in this study.

2021 ◽  
Author(s):  
(MD

Abstract Background: Undiagnosed depression among university students has an adverse effect on the wellbeing and academic performance of students. This study aimed to assess the prevalence of depression and associated factors among Debre Birhan university students. Methodology: Institutional based cross-sectional study design is conducted in Debre Birhan University from April to June 2013 E.C. Three hundred sixty nine students participated in this study which was selected by simple random sampling technique. Data were collected by using a self-administered PHQ-9 standard depression questionnaire. First the data was entered into in Epidata 3.1 and then was exported to SPSS version 20 for analysis. Associated factors were identified using binary logistic regression and variables with a p-value < 0.05 were declared as statistically significant factors with the outcome variables. Result: All of the study subjects were between ages 18 and 33 with a mean age of 22.65 9 ± 2.78. The overall prevalence of depression is 17.1%. Among this according to PHQ-9 scores cut scores, 161(43.6 %) scored as normal (0–4), 145(39.3%) scored as mild (5–9), 53(14.4%) scored as moderate (10–14), 4(1.1%) scored as moderately severe (15–19) and 6(1.6%) students scored as sever (> 20). In multivariate analysis being female AOR = 9.28[3.47–24.81], academic year AOR = 0.236[0.059–0.936], smoking 26.3[9.33–74.1] and alcohol use AOR of 2.62[0.95–7.21] are significantly associated with depression. Conclusion and recommendation: This study found a considerable proportion of undergraduate students with depression. Higher institutions need to pay special attention to students especially those who are female, junior students, smokers and alcohol users.


2020 ◽  
Vol 5 (2) ◽  
pp. 1027-1030
Author(s):  
Shanti Sunuwar Subedi ◽  
Rakina Bhansakarya ◽  
Sajjan Kumar Sharma

Introduction: To evaluate the maternal and perinatal outcome in booked and unbooked cases. Objectives: To assess the maternal and fetal outcomes in unbooked and booked patients. Methodology: This was a cross-sectional comparative study conducted in the Department of Obstetrics and Gynecology from Augustti2019 to January 2020. Using a convenient sampling technique, 204 samples were taken and cross-sectional study was done. Results: There were total 204 cases in this study;102were booked and 102 were unbooked. In this study, 85(83%) of booked cases were educated up to secondary level as compared toti65 (64%) of unbooked cases. There was no significant difference in Apgar score in 1 and 5 minute between booked and unbooked cases. More babies in the unbooked group were transferred to NICU as compared to the booked group and the difference was significant (9.8%vs 1.9%). Greater proportion of booked cases had spontaneous vaginal delivery (81.3% vs 59.8%) and complications like preterm delivery, anemia, preeclampsia/ eclampsia, complicated labor and puerperal sepsis was also less in the booked group. Conclusions: The study showed that unbooked mothers and their newborns had higher chance of having complications.


2020 ◽  
Vol 11 (2) ◽  
pp. 37-42
Author(s):  
Firdausi Ramadhani ◽  
Yanti Hz. Hano

Penelitian ini bertujuan untuk mengetahui beberapa faktor yang berhubungan dengan kejadian bayi Bayi Berat Badan Lahir Rendah (BBLR) di Wilayah Kerja Puskesmas Limboto Kabupaten Gorontalo. Metode yang digunakan adalah  Observasional Analitik dengan pendekatan cross sectional study. Populasi adalah seluruh ibu yang melahirkan berjumlah 853 responden, dengan Sampel yaitu sebanyak 202 responden. Teknik pengambilan sampel menggunakan tekhnik Purposive Sampling. Analisis data menggunakan uji Chi Square. Hasil penelitian menunjukkan proporsi bayi Berat Badan Lahir Rendah (BBLR) 34 responden (16,8%) dan bayi Berat Badan Lahir Normal (BBLN) 168 responden (83,2%). Hasil bivariat didapatkan bahwa ada hubungan pengetahuan (p-value 0,044), pendapatan keluarga (p-value 0,029) dengan kejadian bayi Berat Badan Lahir Rendah (BBLR). Sedangkan, jumlah paritas (p value 0,523),  jarak kehamilan (p-value 0,659), dan Kekurangan Energi Kronik (KEK) (p-value 0,637) tidak memiliki hubungan yang bermakna secara statisti dengan kejadian bayi Berat Badan Lahir Rendah (BBLR).    This study aims to determine several factors associated with the incidence of low birth weight babies (LBW) in the Limboto Health Center, Gorontalo District. The method used is analytic observational with a cross sectional study approach. The population was all mothers who gave birth totaling 853 respondents, with a sample of 202 respondents. The sampling technique used purposive sampling technique. The results showed that the proportion of Low Birth Weight (LBW) babies was 34 respondents (16.8%) and Normal Birth Weight (BBLN) babies were 168 respondents (83.2%). The bivariate results showed that there was a relationship between knowledge (p value 0.044), family income (p value 0.029) with the incidence of low birth weight babies (LBW). Meanwhile, the parity (p value 0.523), pregnancy distance (p-value 0.659), and Chronic Energy Deficiency (P-value 0.637) did not have a statistically significant relationship with the incidence of Low Birth Weight (LBW).


Author(s):  
Fatemeh Rahimi ◽  
Elahe Alamdar ◽  
Hengame Sadat Seyed Mirnasab ◽  
Somaieh Borjalilu ◽  
Mahnaz Pouresmaeil ◽  
...  

Background and purpose: There is concern that students may have an unhealthy lifestyle as a result of changes that occurred during corona conditions, so this study aimed to determine the status of the lifestyle and its relationship with the demographic characteristics of postgraduate students during the corona span.  Material and Methods: This cross-sectional study was conducted at Tehran University of Medical Sciences in 2020. The link to the online Health-Promoting Lifestyle Questionnaire Profile2 was sent to conduct the research. To examine the relationships between the mean scores of health-promoting lifestyle and different variables, an independent samples t-test was applied in the case of dichotomous demographic variables (gender, education level, and income-generating activity), while one-way analysis of variance test was used to evaluate the multilevel demographic variables (marital status, place of residence, and faculty). The Pearson correlation coefficient was also used for testing age.  Results: The sample 240, (75.4%) were female and 145 of them, (60.4%) were single. The mean age of them was 32.21±7.45.45 years old. The lifestyle total score was 138.28± 21.18 at the average level. The highest score was related to spiritual growth (26.93±5.01), whereas the lowest score was reported on physical activity (16.92±5.17). The difference between the mean of health-promoting lifestyle was not significant in terms of demographic variables.According to the results, a statistically significant difference was observed between male and female students in the field of nutrition. Also, students were significantly different in the nutrition domain regarding students’ residence (p-value <0.05). Spiritual growth was significantly different among students in terms of marital status (p-value <0.05). Conclusion: Although the mean score of health-promoting lifestyle was not different from other studies, further studies are proposed to plan health interventions in accordance with epidemic conditions for students. 


2021 ◽  
Vol 12 (2) ◽  
pp. 327
Author(s):  
Ikit Netra Wirakhmi ◽  
Iwan Purnawan

AbstrakLatar belakang: Sampai saat ini, hipertensi masih merupakan tantangan besar di Indonesia. Kepatuhan pasien dalam menggunakan obat berpengaruh terhadap keberhasilan terapi pengobatan. Adanya ketidakpatuhan pasien hipertensi dalam minum obat dapat memberikan efek negative yang sangat besar, seperti munculnya komplikasi. Tujuan: Mengetahui hubungan kepatuhan minum obat dengan tekanan darah pada penderita hipertensi di Puskesmas Karangjambu Kabupaten Purbalingga. Metode: Desain penelitian ini adalah cross sectional study. Responden dalam penelitian ini adalah pasien hipertensi di Puskesmas Karangjambu Kbupaten Purbalingga. Sampel diambil menggunakan teknik accidental sampling dengan jumlah 86 responden. Data dikumpulkan pada bulan Mei 2021 menggunakan kuesioner 8 – Item Morisky Medication Aderence Scale (MMAS – 8) dan pengukuran tekanan darah secara langsung. Hasil: Penelitian ini menunjukkan bahwa Sebagian besar responden adlaah perempuan (86%), sebgain besar berada pada kategori tingkat kepatuhan sedang (47%) dan pada kategori hipertensi tahap 2 (63%). Uji stastistik didapatkan nilai p value 0.901 menunjukkan bahwa tidak ada hubungan kepatuhan minum obat dengan tekanan darah pada penderita hipertensi. Kesimpulan: Tidak ada hubungan kepatuhan minum obat dengan tekanan darah pada penderita hipertensi AbstractBackground: In Indonesia, hypertension is still a major problem. Adherence to treatment is critical for hypertension patients' long-term health and well-being. Adherence are required for hypertension therapy to be effective, and altering these patients' behavior has the greatest potential for improving hypertensive control. Objectives: To explore the relationship between medication adherence and blood pressure in hypertension patients. Methods: We used the cross-sectional study. This research sample was hypertension patients at Karangjambu Health Centre Purbalingga Regency. We included 89 respondents by accidental sampling technique. We collected the data by questionnaire. The Gamma & Sommers’d test was performed to analyze the data. Results: This research showed that that the majority of respondents were women (86%), the moderate category had the highest level of adherence (47%) and the most respondents suffer from hypertension stage 2 (63%). The statistical test result of 0.910 suggested that there was no relationship between medication adherence and blood pressure in hypertensive patients. Conclusions: There was also no significant between medication adherence and blood pressure. 


2021 ◽  
Author(s):  
Rana Kurdi ◽  
Hanan Abdul Rahim ◽  
Ghadir Al-Jayyousi ◽  
Manar Yaseen ◽  
Aetefeh Ali ◽  
...  

Background: Electronic cigarette (e-cigarette) use is becoming popular worldwide especially among youth. Research reported that university students have poor knowledge and misconceptions about the health risks of e-cigarettes, which may lead students to use them even in populations where prevalence of cigarette smoking is relatively low. At this age, the influence of peers is also significant. In this study, we assessed the prevalence of e-cigarette use among university students as well as their knowledge and attitudes towards e-cigarettes. Methodology: We conducted a cross-sectional study among Qatar University students using a self-administered online questionnaire. Descriptive univariate analysis of all variables was conducted as well as a bivariate analysis to check the association of e-cigarette use with selected variables. A binary logistic regression was conducted to assess predictors of e-cigarette use. Results: The prevalence of e-cigarette use among students was found to be 14% where 32% of them were daily users. Approximately 42% of the participants agreed that ‘e-cigarettes are less harmful to health compared to traditional cigarettes, and 45.7% of them agreed that ‘e-cigarettes can prevent smoking traditional cigarettes. The prevalence of e-cigarettes use was 16.2% among males and 12.8% among females, which showed no significant difference between the two genders. Females were more likely to use e-cigarettes because they “don’t smell” (P-value=0.023). The study showed a significant association between e-cigarette use and knowledge items (P-value < 0.05) and having a smoker among siblings or friends. At the multivariate analysis level, only the friends’ effect remained significant after controlling for the other variables (OR= 7.3, P-value=0.000). Conclusion: Our research found that university students have inadequate knowledge and misconceptions in regards to e-cigarettes use, especially among users. Effective smoking prevention policy and educational interventions are needed to enhance awareness among university students about the health effects associated with e-cigarettes use.


2021 ◽  
Vol 8 (9) ◽  
pp. 491-496
Author(s):  
Chirayu N. Pandya ◽  
Donald S. Christian ◽  
Mansi M. Patel

BACKGROUND Smartphone use has gone tremendously up throughout the world during the past decade and addiction potential is well documented among the users. Smartphone addiction among adolescents and young adults should be seen with caution as they lay the foundations not only for their healthy lives but also of the country’s future and its economy, they live in. METHODS Both school and college students aged between 15 - 24 years were enrolled in this cross sectional study, using systematic random sampling technique to determine smartphone addiction potential through Smartphone Addiction Scale (SAS). The possible factors contributing to SAS scores were also determined through statistical tests (Chi-square test, Kruskal-Wallis H test and Mann Whitney U test). RESULTS Among a total of 239 respondents of age 15 to 24 years (mean age 18.5 ± 2.35 years), there were 124 (51.9 %) females and 231 (96.7 %) belonged to the urban area. Most of the participants were studying in high school (40.6 %) followed by medical field (40.2 %). A total of 110 (46 %), students had used their smartphone commonly for social media purpose, followed by entertainment purpose (29.3 %), education (36 %), web surfing (20 %). The median daily usage of smartphone was found to be 4 hours among participants. The mean score of SAS was found to be 103.59 ± 25.08. There was statistically significant difference in SAS score according to age group, according to their smartphone usage per day, according to common purpose of usage of smartphone and also according to their streams, and monthly expenses the student spends to recharge their smartphone. CONCLUSIONS Smartphone addiction potential was determined according to various social and demographic characteristics. Factors causing smartphone addiction should be tackled by multiple stakeholders to reduce the chances of addiction due to smartphone and to protect them from future health consequences. KEYWORDS Adolescent, Smartphone Addiction, Smartphone Addiction Scale, Young Adults


2015 ◽  
Vol 4 (1) ◽  
Author(s):  
Rafika Oktova ◽  
Desmiwarti Desmiwarti ◽  
Arni Amir

AbstrakDepo Medroksiprogesteron Asetat dan Implant Levonorgestrel merupakan kontrasepsi hormonal progestin sintetik yang memiliki efek samping yaitu peningkatan berat badan dan mempengaruhi metabolisme lipid. Tujuan penelitian ini adalah untuk mengetahui perbedaan profil lipid pada akseptor Depo Medroksiprogesteron Asetat dengan Implant Levonorgestrel. Ini adalah studi observasional dengan desain cross sectional comparative. Penelitian dilakukan di laboratorium Bagian Biokimia Fakultas Universitas Andalas dari Maret sampai Mei 2014. Subjek penelitian terdiri dari dua kelompok, masing-masing 20 subjek. Pemeriksaan dengan metode enzimatis kolorimetri yaitu GPO-PAP untuk trigliserida, dan CHOD-PAP untuk kolesterol total, HDL dan LDL. Data dianalisis menggunakan uji t dengan nilai p<0.05 dianggap bermakna secara statistik. Rerata kadar LDL pada Depo Medroksiprogesteron Asetat lebih tinggi (95,51 ± 20,47) mg/dl daripada Implant Levonorgestrel (79,35 ± 12,55) mg/dl dengan nilai p<0,05 artinya terdapat perbedaan yang bermakna sedangkan kadar trigliserida, kolesterol total dan HDL tidak bermakna. Kesimpulan penelitian in adalah terdapat perbedaan yang bermakna rerata kadar LDL pada Depo MedroksiprogesteronAsetat dan Implant Levonorgestrel, sedangkan kadar trigliserida, kolesterol total dan HDL tidak bermakna. Secara klinis profil lipid pada kedua kelompok dalam keadaan normal.Kata kunci: profil lipid, depo medroksiprogesteron asetat, implant levonorgestrelAbstractDepo Medroxyprogesterone Acetate and Levonorgestrel Implants are synthetic progestine hormonal contraceptives that have side effect in body weight and lipid metabolism. The objective of this study was to determine the differences of lipid profile between acceptors Depo Medroxyprogesterone Acetate and Levonorgestrel Implants. This was a comparative cross sectional study. The study was done at laboratory of Biochemistry Departement in Medical Faculty of Andalas University from March until May 2014. The subjects were consisted of two groups, each group had 20 subjects. The examination used an enzymatic colorimetric method GPO-PAP for trygliserides and CHOD-PAP for total cholesterol, HDL and LDL. Data was analyzed using analysis of t-test with p<0.05 was considered to be significantly different. LDL levels average in Depo Medroxyprogesterone Acetate was (95,51 ± 20,47) mg/dl and Levonorgestrel Implants was (79,35 ± 12,55) mg/dl with p-value, it means there is a significantly difference, but levels of trygliserides, total cholesterol and HDL means there is no significantly difference. This research concluded that there is a significant difference on average levels of LDL in the Depo Medroxyprogesterone Acetate and Levonorgestrel Implants but levels of trygliserides, total cholesterol and HDL there is no significantly difference. The clinically lipid profile in the two groups is in normal range.Keywords: lipid profile, depo medroxyprogesterone acetate and levonorgestrel implants


Thrita ◽  
2020 ◽  
Vol 9 (1) ◽  
Author(s):  
Fatemeh Mousavi ◽  
Parisa Shojaei ◽  
Azadeh Nazemi ◽  
Atefe Dadashi

Objectives: This research has been conducted to study antibiotic self-medication, prevalence, and reasons. Methods: A questionnaire containing 30 comprehensive questions in terms of the experience of antibiotic self-medication was prepared. In this cross-sectional study, data were analyzed using analytical statistics bases on chi-square and logistic regression. Results: The results showed that 61.3% of the participants were self-antibiotic users. There was a significant difference only between gender and self-medication such that self-medication in males was more than females (P value = 0.027). Conclusions: Self-medication of antibiotics is almost high and requires more information about the side effects of these drugs in order to promote rational and physically prescribed use.


2021 ◽  
Vol 16 (1) ◽  
Author(s):  
Shailaja Khadka ◽  
Sumana Thapa ◽  
Ratna Khatri ◽  
Rosy Malla ◽  
Sumana Thapa ◽  
...  

Aim: To determine the prevalence of anxiety in pregnancy during COVID19 pandemic in Shree Birendra Hospital, Chhauni Method: It is a cross sectional study conducted at Shree Birendra Hospital Chhauni from July to October 2020 following the ethical approval from IRC. All the pregnant women from first to last trimester attending outdoor visit were included; they were asked to fill up Beck Anxiety Index form. The level of anxiety was compared with demographic data like age, race, parity, and period of gestation, education and occupation. Data were analyzed by using SPSS 20 software. Results: A total of 385 presumably uninfected pregnant women were surveyed in 20-40 (28.45±3.95) years age group from 4 to 41 (27.15±9.4) weeks of pregnancy and 55.6% were multipara. Low-grade anxiety was found 99.5% (BAI= 3.06±3.66). Conclusions: Low-grade anxiety was found in almost all pregnant women during covid pandemic and there was no significant difference by demographic variables.


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