scholarly journals Clinical and epidemiological profile of neurocysticercosis in children

2020 ◽  
Vol 7 (11) ◽  
pp. 2210
Author(s):  
Preeti Lata Rai ◽  
Gunjan Kochar ◽  
P. L. Prasad

Background: This study was done to describe the clinical and epidemiological profile of neurocysticercosis in children of Rohilkhand region.Methods: The study was carried out in the Paediatric Department (Paediatric Intensive Care Unit and General Ward) of Shri Ram Murti Smarak Institute of Medical Sciences, Bareilly, Uttar Pradesh. It was a prospective clinical observational study. After IEC approval and written informed consent, all children between the age group of one month to sixteen years, who fulfilled the inclusion criteria, that is, presented with unprovoked seizure and had evidence of active and ring enhancing lesion or mixed lesion on CT Scan/MRI of brain were enrolled in the study. Detailed history and clinical examination were carried out. Seizures due to any other CNS pathology were excluded. Simple tests for measures of dispersion were the statistical tests that were used.Results: Statistically forty children fulfilled the inclusion criteria. Of the total children enrolled in the study, 63% were males. Male to female ratio was 1.7. Almost three fourths of the population belonged to rural backgrounds. The mean age of studied children was 10.5 years. More than half of the affected children belonged to the school going age group. Generalised tonic clonic seizures were more common in all age groups than partial seizures. Headache (52.6%), loss of consciousness (42.1%), vomiting (31.5%) and focal neurological deficit (15.7%) were the most common presenting complaints in order of decreasing frequency.Conclusions: There should be a high index of suspicion of NCC in any child presenting with unprovoked seizures.

2021 ◽  
Vol 11 (2) ◽  
pp. 253-257
Author(s):  
Sunil Kumar Agarwalla

Seizure in children are generally indicating a potentially serious underlying systemic or CNS disorders that require thorough clinical examination, investigation and management. It is therefore important to establish accurate diagnosis of seizure and its etiology to manage such patients appropriately. We carried out this study to evaluate different etiology of seizures and its correlation with abnormal EEG & abnormal neuroimaging in the age group of 2mo to 14 years. 200 children presented with seizure to our department from January 2019 to November 2020 were enrolled in this prospective hospital-based study. Detailed history, clinical examination, investigation with special emphasis to EEG & neuroimaging was done and different correlation was drawn by using SSPS 18.0 statistical analysis. Among 200 cases, 6 to 10yr. age group constituted maximum (49%) number of cases. Male to female ratio is 1.5:1. GTCS is the predominant pattern of seizure (60%) in all age groups. EEG abnormality is found in 45%, mostly in focal seizure type. Neuroimaging abnormality found in 29%. Maximum cases (30%) had infectious etiology. Childhood seizure needs detailed history taking and careful examination. Vedio recording shown by parents / caregivers really help towards differentiating seizure from seizure mimics. EEG has a role in specific seizure type; Neuroimaging at times helps in diagnosis. There are few studies that describe neuroimaging [Computed Tomography (CT) and Magnetic Resonance Imaging (MRI)] and Electroencephalogram (EEG) data in children who present with new-onset seizures. The EEG is recommended as a part of the neurodiagnostic evaluation of the child with an apparent first unprovoked seizure.


2009 ◽  
Vol 3 (4) ◽  
pp. 998
Author(s):  
Rita De Cássia Rocha Moreira ◽  
Ludmilla Oliveira Souza ◽  
Manoela De Assis Silva Carvalho ◽  
Scheila Conceição Sacramento Saldanha

Objective: to determine the cervical cancer epidemiological profile in Feira de Santana city, from 2000 to 2004. Methods: documental research, quantitative methods, descriptive, whose data collection were in annual reports issued by the Municipal Secretariat of Health through the Information System in Cancer of the Uterine Cervix (SISCOLO). The collection instrument was a form consolidated. Descriptive analysis was conducted using statistical tests, calculating the incidence, relative frequency and mortality rates by age. The results are presented in tables. Results: regards to Cervical Intra-epithelial Neoplasia I (CIN I) the age group between 20-39 years old had the greatest number of cases, but in relation to CIN II the age group between 20-39 years old not presented cases in 2004. In CIN III there was an increase in the percentage distribution in the age group between 20-39 years old, there was a decrease in women between 40-59 years old and over 60 years old there were cases only occurred in 2002. The hospital morbidity predominated in the age group between 40-59 years. The absolute frequency shows decrease in the number of cases of hospitalization. Deaths by cervical cancer were predominant in the age group over 60 years old. Conclusion: to know cervical cancer epidemiological variables is fundamental because it makes possible to draw actions which contribute to the women’s health promotion. Descriptors: cancer; cervix uteri; prevention; epidemiology.


Author(s):  
CC Nwafor ◽  
K Obioha ◽  
TO Akhiwu

Ascites is a symptom that can originate due to diverse pathologies. A lot of investigations including ascitic fluid cytology (AFC) can be done on it to help determine its origin. The aim of this study, is to document the findings and highlight the importance of AFC in patient care in Uyo. All AFC reports and slides in the Department of Histopathology, University of Uyo were retrieved, reviewed and used for this study. The age ranged from 1.5 – 80 years with mean age, 41.79 (±17.23) years. About 71.8% of the ascitic fluid (AF) specimens were from patients between the 3rd and 6th decade. Females predominated in all age groups expect 10-19 year's group, with a male to female sex ratio of 1:2.4. Malignant cells were seen in 28.7% of all the samples, while 51.2% were negative for malignant cells. Malignant cells were seen in 4 (6.7%), 11 (18.3%) and 6 (10%) of the AFC performed due to various liver pathologies, ovarian malignancies and intra-abdominal malignancies respectively. Malignant cells were found more in females with a male to female ratio of 1: 3.6. Age group 40-49 years accounted for most of the malignant cases (26.6%). The pattern of AFC in Uyo is similar to the pattern in other parts of Nigeria


2019 ◽  
Vol 27 (2) ◽  
pp. 113-120
Author(s):  
Sabyasachi Ghosh ◽  
Tarak Nath Saha ◽  
Indranil Sen

Introduction   Head and neck lesions encompass a multitude of disorders which can be broadly classified into two groups: Benign and Malignant. Overall 57.5% of global head and neck cancers comes from Asia itself and India alone constitutes 30% of it. Therefore, it is of prime essence that need based and coordinated research for understanding the threats to the nation from chronic diseases such as head and neck cancers and ways to defy such threats should gain the utmost importance. The present study attempts to present the epidemiological profile of the patients attending a peripheral referral institute of this state with head-neck pathologies and has undergone a histopathological examination of their lesions within a period of three years period (2016-18) based on the histopathological evidences. Materials and Methods The accumulated data regarding the aforesaid patients as per records of the histopathological reports available in the Department of Pathology was used as the primary material and the interrelation of different epidemiological parameters were studied using the statistical methods Results Six hundred and eighty seven cases from the head and neck region were analysed during this three-year period. Age range was from 3 years to 96 years with maximum cases in the age group of 20-29 years (16.1%). The Male: Female ratio in our study was 1.34:1 (Males 394, Females 293). In this study, 38.8% benign, 32.46% malignant, 25.32% inflammatory and 3.3% congenital cases were recorded. Maximum number of benign lesions was in the age group of 10-39 years. Malignancies were noted to be higher in ages 40 years and above. Squamous cell carcinoma was the most common malignancy observed. Conclusion  Specific data obtained like this from histopathological records is helpful in evaluating patterns of head and neck lesions and augment the base line data of institute and the region.


2018 ◽  
Vol 5 (3) ◽  
pp. 862
Author(s):  
C. P. V. Ramana Sastry ◽  
R. Manohar Reddy

Background: To study the prevalence and clinical spectrum of seizures and treatment outcome in children.Methods: A hospital based prospective study was done at Maheshwara Medical College and Hospital, Patancheru, Telangana in the department of Paediatrics over one-year period. A total of 75 cases presenting with seizures were studied for demographics, clinical features, imaging studies where possible and patient response to treatment.  Results: T Patient age ranged from one week to 14 years with male to female ratio of 1:4. Majority were in the age group of 1-3 years 25/75 (33.3%). Fever was present on admission in 66.6% of cases in 1 month to 6 years. Unprovoked seizure was common 20/75 (26.6%) in age group 6 to14 years. Neonatal seizures were seen in 6.6% cases. Generalized tonic clonic seizures were common and were seen in 63.3% cases. Only 5 (6.6 %) cases presented with status epilepticus. CT scan was done in 20 cases in unprovoked seizures and showed various etiologies. Conclusions: Seizures in children are a common indication for hospital admission. They can be febrile or unprovoked. CNS infections and space occupying lesions are common causes for paediatric seizures. Early detection of the cause of seizures helps in instituting appropriate treatment. Children with unprovoked seizures should be on regular long term follow up and treatment.


2021 ◽  
Author(s):  
Wenli He ◽  
Danhong Xu ◽  
Jiafeng Wang ◽  
Yuze Shen ◽  
Zheng Lin ◽  
...  

Abstract BackgroundLittle is known about the gender characteristics and the Corona Virus Disease 2019(COVID-19) impact on psychiatric department outpatients in general hospitals in China. MethodsWe retrospectively collected 225,947 outpatient clinic records before and during COVID-19 pandemic from January 1, 2019 to December 31, 2020 in the psychiatric clinic of 3 general hospitals, gender composition of patients was analyzed in different five age groups and nine diagnostic categories at three levels: total patient visits, number of patients and number of first-visit patients. ResultsThe total male-to-female ratio of psychiatric outpatient records in 3 general hospitals from 2019 to 2020 was 1:1.69. Women were more common in all age groups and the male-to-female ratio of 2020 was expanded compared to that of 2019, especially in age group below 34 years old and anxiety disorders category. Most mental disorders showed higher demands for females than that for males except Mental and behavioral disorders due to psychoactive substance use with the male-to-female ratio was 1:0.05. Compared to 2019, the proportions of women were expanded especially in age group below 34 years old, and anxiety disorder and undetermined diagnosis categories were significantly increased in 2020. ConclusionsThe demand for female psychiatric outpatient services is obviously higher than that for males. It is necessary to pay more attention to explore targeted mechanism or psychosocial service strategy for female patients with mental disorders. Trial registration: ChiCTR2100044894, March 31,2021 retrospectively registered.


2018 ◽  
Vol 5 (2) ◽  
pp. 445 ◽  
Author(s):  
Khalilur Rahman A. ◽  
Jawahar Krishnaswamy ◽  
Muthukumaran G. ◽  
Sanjay Prakash J.

Background: Ileal perforations are a common occurrence in our hospital setup with a majority of cases having an etiology of typhoid. The presentation and management of ileal perforation with special reference to typhoid, nonspecific and traumatic perforations and the outcomes in these patients and the factors affecting prognosis are important. Aims and objectives of the study were to study the management of Ileal perforation. To compare the outcome of two different types of treatment for Ileal perforation i.e. Primary Closure (vs) Resection and Ileostomy.Methods: This is a randomized comparative observational study conducted in general surgery department of Saveetha Medical College and Hospital, Chennai between February 2016 to October 2017. A Minimum of 28 patients was included in the study. Diagnosis was made on the basis of the X-ray erect abdomen, ultrasound abdomen, Widal test and intra-operative findings.Results: The common age groups affected was 41-50 years age group (5 patients) and 61-70 years age groups (5 patients). The least affected were 1-10years age group (one patient). The incidence in males was slightly greater than females. Male to female ratio was 2.5:1. Typhoid perforation is the most common case of ileal perforation followed by non-specific perforation. Post-operative complications are more in the primary closure group with 32.14% (9 patients) which is lower when compared to ileostomy group 17.85% (5 patients). Complications of primary closure were wound infection (2 patients), burst abdomen (3 patients), faecal fistula (1 patient), respiratory complications (3 patients). Complications in ileostomy group were wound infection (4 patients) and respiratory complications (one patient).Conclusions: Mortality was more in primary closure group with 21.42% (6 patients) and mortality was less in ileostomy group with 7.14% (2 patients). This study proposes that ileostomy may be given priority over other surgical options in moribund patients.


Author(s):  
Mohan M. Desai ◽  
Deven R. Kuruwa ◽  
Easwar Elango ◽  
Roshan Wade

<p class="abstract"><strong>Background: </strong>Implementing appropriate fracture control measures and treatment protocols is crucial to maximizing health and development gains. This requires an in depth understanding of age-specific, sex-specific and cause-specific injury patterns at the national and subnational levels. No such study on fracture epidemiology has been undertaken in the Indian population.</p><p class="abstract"><strong>Methods: </strong>Study was conducted in a tertiary care centre (KEM hospital, Mumbai) which is one of the highest volume trauma centres in the country. Data of 3000 patients was obtained from the medical records department for the year 2016-2019. Patients were segregated with respect to their genders and into three age groups. Etiology of fracture was noted, and fractures classified according to the anatomical area. Whether the patient received conservative or operative management was also recorded.</p><p class="abstract"><strong>Results: </strong>43.83% of the fractures occurred in 18-50 years age group. 41.33% in the above 50 group and only 14.73% in the below 18 age group. Overall male to female ratio was 1.4: 1. Vehicular accident was the most common mode of injury (47.07%) followed by fall from height (21.03%). Proximal femur fractures were the most common accounting for 19.57% of all fractures followed by forearm (10.53%), tibia diaphysis (8.10%). Talus was the least common. 81.07% cases were managed operatively and 18.93% conserved.</p><p class="abstract"><strong>Conclusions: </strong>Our study highlights that Indian epidemiology is unique from our Western counterparts. Population affected is much younger, old age males are affected more than females. Lower limb fractures are more prevalent and road traffic accidents are responsible for almost half the fractures.</p>


2020 ◽  
Vol 10 (3) ◽  
Author(s):  
Renata Pinto ◽  
Isadora Borges ◽  
Jonas Amorim

INTRODUCTION: The impact of COVID-19 on the Brazilian pediatric population may be underestimated by underreporting. This study compares the incidence of hospitalizations and deaths due to severe acute respiratory syndrome (SARS) and etiologies in children between 2019 and 2020. METHODS: Epidemiological study carried out by consulting InfoGripe. Data referring to epidemiological weeks 1 to 25 of the years 2019 and 2020 were consulted, analyzed using the SPSS 26.0 program. RESULTS: Comparing the years 2019 and 2020, we observed reduction in the incidence rate (per 100,000) of hospitalizations for SARS in the 0-4 year age group from 4.023 to 2.980 (p = 0.05), and an increase in the other age groups, in schoolchildren, 0.353 to 0.618 (p = 0.009) and among adolescents, 0.115 to 0.393 (p = 0.002). There was an increase in deaths from 0.013 to 0.017 (p = 0.05) between 5-9 years, and from 0.009 to 0.029 (p = 0.001) between 10-19 years. In relation to “unknown etiology”, the incidence of hospitalizations increased from 0.294 to 1.454 (p = 0.007) and deaths from 0.03 to 0.28 (p = 0.004). CONCLUSION: The incidence of hospitalizations and deaths due to SARS in 2020 in children aged 5-9 and 10-19 years was higher than in 2019. The 3.4-fold increase in the number of cases, and 9.3-fold increase in deaths from SARS without a defined etiology in 2020 may suggests an important underreporting by COVID -19 in Brazil. Further studies are needed to assess the extent and impact of SARS-CoV-2 in children.


2017 ◽  
Vol 4 (6) ◽  
pp. 1979
Author(s):  
Amul Bhedi ◽  
Miten Prajapati ◽  
Arnab Sarkar

Background: Intestinal obstruction can occur at any age in the paediatric population1-4. Bowel obstruction in children differs from that in adults in terms of etiology, presentation and even the management. The aim of the study was to find out various etiologies, clinical features, outcome and mortality of paediatric age groups with intestinal obstruction and their relation to age and sex distribution.Methods: This is a prospective study of 50 cases of paediatric age group with signs and symptoms of intestinal obstruction which were admitted in Sir Sayajirao Gaekwad Hospital, Vadodara, India during period of December 2004 to November 2006. Surgical intervention was carried out where indicated otherwise patients were managed conservatively. Data was analysed in SPSS version 10 statistical software for percentage and frequencies.Results: Total 50 patients were included in the study. Among these 30 were males and 20 were females with M: F ratio of 3:2. Majority of them were 25 neonates of age group of 1-7 days (50%), followed by 7 infants of 1 months- 1 years (14%) and 18 children aged 1 years-12 years (36%).  Out of 50 patients, 41 (82%) patients had congenital causes in which 21(42%) patients had imperforate anus followed by Hirschprung’s disease in 8(16%), Meckel’s diverticulum in 6(12%), jejunal atresia in 4(8%), hypertrophic pyloric stenosis in 2 patients (4%) and 9(18%) patients had acquired causes in which intussusception was in 5(10%) patients, abdominal tuberculosis in 2(4%) and gangrenous appendix in 2(4%) patients. Total mortality was 6 out of 25 neonates and there were no mortality in infants and children groups.Conclusions: Majority of patients were neonates than infants and children with slight male preponderance with male: female ratio of 3:2. Congenital causes of intestinal obstruction were more common (82%) than the acquired causes (18%). Postoperative septicaemia was more common and overall mortality was exclusively in neonates.


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