scholarly journals Changes in lipid profile and some biochemical parameters in postmenopausal women treated with honey

2021 ◽  
Vol 7 (1) ◽  
pp. 31-36
Author(s):  
E C Ogbodo ◽  
B N Ugorji ◽  
S C Meludu ◽  
I S I Ogbu ◽  
L O Egejuru ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Waist Circumference ◽  
Lipid Profile ◽  
Postmenopausal Women ◽  
Biochemical Parameters ◽  
Research Subjects ◽  
Anthropometric Parameters ◽  
Baseline Values ◽  
The Difference ◽  
Natural Honey

The study investigated the effect of natural honey on the lipid profile and some biochemical parameters among postmenopausal women, aged 45-65 years old. Sixty healthy postmenopausal women were given 20 g/day of natural honey and followed up for three months. The primary outcome was changes from baseline on the lipid profile and the chosen biochemical parameters (fasting blood sugar, serum calcium) and some anthropometric parameters. Paired t-test was performed to evaluate the difference between the baseline and the 3 month values of the parameters and lipid profiles. Sixty postmenopausal women successfully completed the study. The result showed that there were significant increases in HDL-C, calcium and significant decreases in LDL-C, TG, TC, and FBS concentrations in the blood of the research subjects after three months of treatment with honey compared with the values at baseline (p<0.05). Also there were significant decreases in the blood pressure, weight and waist circumference of the postmenopausal women after treatment when compared with baseline values (p<0.05). Natural honey helps in improving the lipid profile, FBS, Blood pressure, weights and waist circumference of postmenopausal women and can be included as part or alternative remedies in management of postmenopausal conditions.

scholarly journals Effects of Triphala on Lipid and Glucose Profiles and Anthropometric Parameters: A Systematic Review

2021 ◽  
Vol 26 ◽  
pp. 2515690X2110110
Author(s):  
Wiraphol Phimarn ◽  
Bunleu Sungthong ◽  
Hiroyuki Itabe
Keyword(s):  
Body Mass Index ◽  
Body Weight ◽  
Blood Glucose ◽  
Waist Circumference ◽  
Lipid Profile ◽  
Body Mass ◽  
The Body ◽  
Current Evidence ◽  
Diabetic Patients ◽  
Anthropometric Parameters

Aim. The efficacy of triphala on lipid profile, blood glucose and anthropometric parameters and its safety were assessed. Methods. Databases such as PubMed, ScienceDirect, Web of Science, and Thai Library Integrated System (ThaiLIS) were systematically searched to review current evidence of randomized controlled trials (RCT) on triphala. RCTs investigating the safety and efficacy of triphala on lipid profile, blood glucose and anthropometric parameters were included. Study selection, data extraction, and quality assessment were performed independently by 2 authors. Results. Twelve studies on a total of 749 patients were included. The triphala-treated groups showed significantly reduced low-density lipoprotein-cholesterol, total cholesterol and triglyceride in 6 studies. Five RCTs demonstrated triphala-treated groups led to statistically significant decrease in body weight, body mass index and waist circumference of obese patients. Moreover, triphala significantly decreased fasting blood glucose level in diabetic patients but not in people without diabetes. No serious adverse event associated with triphala was reported during treatment. Conclusions. This review summarized a current evidence to show triphala might improve the lipid profile, blood glucose, the body weight, body mass index and waist circumference under certain conditions. However, large well-designed RCTs are required to confirm this conclusion.

scholarly journals The association of depression with metabolic syndrome parameters and malondialdehyde (MDA) in obese women: A case-control study

2021 ◽  
Vol 11 (4) ◽  
pp. 492-497
Author(s):  
Elnaz Vaghef-Mehrabani ◽  
Azimeh Izadi ◽  
Mehrangiz Ebrahimi-Mameghani
Keyword(s):  
Oxidative Stress ◽  
Blood Pressure ◽  
Metabolic Syndrome ◽  
Depressive Symptoms ◽  
Lipid Profile ◽  
Case Control Study ◽  
Case Control ◽  
Obese Women ◽  
Anthropometric Parameters ◽  
Control Study

Background: There is evidence for a bidirectional association between obesity and depression, and obesity is the main risk factor for metabolic syndrome (MetS). This study aimed to compare oxidative stress and MetS features between depressed and non-depressed obese women and study the association of depressive symptoms, oxidative stress, and components of MetS. Methods: In this case-control study conducted in Tabriz (East Azarbaijan, Iran), obese women (body mass index [BMI]: 30-40 kg/m2 ) with a primary diagnosis of major depressive disorder (MDD; based on diagnostic interview with a psychiatrist; n=75) and their age-matched non-depressed controls (n=150) were enrolled. Beck Depression Inventory-version II (BDI-II) was used to assess depressive symptoms in both groups. Anthropometric parameters, blood pressure, fasting blood sugar (FBS), lipid profile and malondialdehyde (MDA) were measured. Results: No significant differences in anthropometric parameters and blood pressure were observed between the two groups. However, FBS of the MDD group was significantly higher than the control (P<0.05). FBS was significantly correlated with BDI-II scores (r=0.158, P=0.017). No significant difference in lipid profile was observed between the groups. Serum MDA level was significantly lower in the MDD group and was inversely associated with BDI-II scores (r=-0.328, P<0.001). Overall, MDD was not significantly associated with MetS in our study (OR=0.848, 95% CI: 0.484, 1.487; P=0.566). Conclusion: Although we found a correlation between higher depressive symptoms and some adverse metabolic outcomes, our findings do not support a significant association between MDD and MetS.

scholarly journals Effect of Losartan on Different Biochemical Parameters in Essential Hypertensive Patients

2019 ◽  
Vol 12 (04) ◽  
pp. 1827-1833
Author(s):  
Pratibha S. Salve ◽  
Chitra C. Khanwelkar ◽  
Preeti S. Salve ◽  
Vandana M. Thorat ◽  
Somnath M. Matule ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Uric Acid ◽  
Angiotensin Ii ◽  
Lipid Profile ◽  
Blood Sugar ◽  
Biochemical Parameters ◽  
Renin Angiotensin System ◽  
Hdl Cholesterol ◽  
Serum Electrolytes ◽  
Significant Difference

The renin–angiotensin system (RAS) provides the most powerful regulation of blood pressure and angiotensin II is the primary mediator in this system. The binding of angiotensin II to AT1 receptors produces a number of potentially harmful effects that include increase in blood pressure, progression of atherosclerosis, myocardial and vascular hypertrophy. Losartan was the first ARB and found to reduce the risk of stroke, new onset of diabetes and to have a proven benefit in stroke. The present study was designed to evaluate the effect of losartan on different biochemical parameters viz; blood sugar, lipid profile, uric acid and serum electrolytes. 29 newly diagnosed patients of either gender with essential hypertension were included in the study. Baseline readings of lipid profile, serum electrolytes, fasting blood sugar and uric acid were recorded before starting losartan monotherapy and were repeated after six months. After comparing the means, it was revealed that there was a significant increase in HDL cholesterol and a significant decrease in serum uric acid levels after six months of losartan therapy. No significant difference was found in blood sugar and electrolyte levels. These findings suggest that losartan can be an attractive option for the treatment of hypertension and for metabolic syndrome.

scholarly journals Relationship between Anthropometric Parameters and Lipid Profiles in University Students from Popayán (Cauca, Colombia)

2020 ◽  
Vol 11 (2) ◽  
Author(s):  
Nancy Janneth Molano-Tobar ◽  
Andres Felipe Villaquiran Hurtado ◽  
María del Mar Meza-Cabrera
Keyword(s):  
Waist Circumference ◽  
University Students ◽  
Lipid Profile ◽  
Total Cholesterol ◽  
Lipid Profiles ◽  
Overweight And Obesity ◽  
The Body ◽  
Anthropometric Parameters ◽  
Sample Distribution ◽  
The Relationship

Introduction: Overweight and obesity are pathologies that are increasing every day. This study was aimed to determine the relationship between anthropometric variables and lipid profiles in a sample of young university students, which leads to taking future prevention actions. Materials and Methods: A descriptive correlational study was conducted with a sample of 182 university students (88 women and 94 men), whose anthropometric variables and lipid profiles were evaluated. Data were analyzed using the SPSS Statistics 20 software. The sample distribution was analyzed using the Kolmogorov-Smirnov normality test. Results were expressed as mean ± standard deviation or percentage, as applicable. Significance was established under the Pearson’s correlation coefficient with p ≤0.05 value. Partial correlations were used to evaluate the relationship between each of the anthropometric risk indices and lipid profile values. Results: 46.7% of the population were overweight classifies as low-risk for waist circumference (45.1%), finding that the body adiposity index was healthy for their age in 64.5% of the participants. As for lipid profile, normal values for triglycerides were found in 60.4% of the participants and optimal values for total cholesterol in 56%. Correlational analysis with a significance of p≤0.005 was positive for gender with anthropometric variables such as Body Mass Index and waist circumference. Discussion: Anthropometric characteristics are closely related to the lipid profile behavior, as shown in this study, and the different research studies conducted with university students. Conclusions: Anthropometric variables are positively related to the gender of university students, finding an association between total cholesterol and triglycerides, which indicates a health risk factor. How to cite this article: Molano-Tobar Nancy Janneth, Villaquiran-Hurtado Andrés Felipe, Meza-Cabrera María del Mar. Relationship between Anthropometric Parameters and Lipid Profiles in University Students from Popayán (Cauca, Colombia). Revista Cuidarte. 2020; 11(2): e1079. http://dx.doi.org/10.15649/cuidarte.1079

scholarly journals MMPs and TIMPs levels are correlated with anthropometric parameters, blood pressure, and endothelial function in obesity

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Soumaya Boumiza ◽  
Karim Chahed ◽  
Zouhair Tabka ◽  
Marie-Paule Jacob ◽  
Xavier Norel ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Metabolic Syndrome ◽  
Endothelial Function ◽  
Biochemical Parameters ◽  
Anthropometric Parameters ◽  
Obese People ◽  
Doppler Flowmetry ◽  
Related Disease ◽  
Clinical Biomarkers ◽  
Obese Subjects

AbstractThe association between matrix metalloproteinases (MMPs), tissue inhibitor of metalloproteinases (TIMPs) and obesity as well as obesity-related disease including metabolic syndrome is not fully explored. Our aims are that: (i) to evaluate the plasma levels of MMP-1, MMP-2, MMP-3, MMP-9, TIMP-1, TIMP-2 and their ratios in non-obese people, overweight and obese people with or without metabolic syndrome, (ii) to investigate correlations between MMPs or TIMPs levels and several anthropometric parameters, blood pressure, endothelial function. Anthropometric and biochemical parameters were determined in 479 randomly selected participants, subdividing according to body mass index (BMI) and metabolic syndrome status. Plasma MMPs and TIMPs levels were measured. The assessment of endothelial function was characterized in people with obesity, overweight and non-obese, using laser Doppler Flowmetry. Obese people have elevated MMP-1, MMP-2, TIMP-1, TIMP-2 levels and decreased MMP-3/TIMP-1 and MMP-9/TIMP-1 ratios compared with non-obese people. MMP-1 levels and MMP-1/TIMP-1 ratio were positively correlated with BMI and waist circumference (WC) while MMP-2 levels were negatively correlated with BMI and WC values in obese people. MMP-3 levels and MMP-3/TIMP-1 ratio were positively correlated with systolic blood pressure (SBP) or diastolic blood pressure (DBP) in obese and metabolic syndrome people. Additionally, MMP-9 levels and MMP-9/TIMP-1 ratio were negatively correlated with endothelium-dependent response in obese and metabolic syndrome people. MMP-1, MMP-2, TIMP-1, TIMP-2 levels were increased in obese subjects. Significant correlations between anthropometric parameters and MMP-1 as well as MMP-1/TIMP-1 ratio supported these results. MMP-3 and -9 levels as well as their ratios with TIMP-1 were associated with blood pressure and endothelial-dependent response, respectively. In conclusion, our results demonstrated that MMP-1, MMP-3 and MMP-9 levels were correlated with several obesity-related parameters including BMI, WC, blood pressure and endothelial-dependent response. Our findings will hopefully provide new aspects for the use of MMPs and TIMPs as clinical biomarkers in obesity-related cardiovascular diseases such as metabolic syndrome and hypertension. The lack of measure of MMPs activity in plasma and relevant organs/tissues in obesity and metabolic syndrome is considered as a limitation in this report.

scholarly journals Intraocular pressure in postmenopausal Nigerian women with and without systemic hypertension

2011 ◽  
Vol 70 (3) ◽  
Author(s):  
J. A. Ebeigbe ◽  
P. N. Ebeigbe ◽  
A. D. A Ighoroje
Keyword(s):  
Blood Pressure ◽  
Intraocular Pressure ◽  
Postmenopausal Women ◽  
Systemic Blood Pressure ◽  
Systemic Hypertension ◽  
Systemic Blood ◽  
Nigerian Women ◽  
The Difference ◽  
Post Menopausal ◽  
The Right

Background: Mean intraocular pressure (IOP) in postmenopausal women has been reported higher than that in menstruating women. Also, intraocular pressure is said to be positively correlated with systemic blood pressure. No previous study in Nigeria has compared intraocular pressure in postmenopausal women with and without systemic hypertension. Purpose: To investigate the effects of menopause on intraocular pressure in subjects with and without high blood pressure. Methods: Normotensive and hypertensive premenopausal and postmenopausal subjects in the   same agerange of 45 to 55 years were studied. Intraocular pressure was measured with the hand-held Kowa applanation tonometer.  Blood pressure was taken in the sitting position at the right upper arm using a manual mercury sphygmomanometer with the right cuff size. The average of two readings was recorded. Results: Mean IOP for premenopausal normotensive women was 14.58 ± 2.56 mmHg whilethat of postmenopausal normotensive women was16.15 ± 1.80 mmHg (p<0.05).  Also, the difference in mean IOP between premenopausal hypertensive (16.58 ± 3.23 mmHg) and postmenopausal hypertensive women (18.24 ± 3.89 mmHg)was statistically significant (p<0.05). A statistically significant and positive correlation was observed between IOP and systemic blood pressure in postmenopausal hypertensive women, p<0.05.Conclusion: Menopause significantly increases intraocular pressure. Mean intraocular pressure of hypertensive postmenopausal women was significantly higher than that of normotensive post-menopausal women, (p<0.05). Knowledge of the normal level of intraocular pressure during various stages of the female reproductive cycle may help during glaucoma screening. (S Afr Optom 2011 70(3) 117-122)

scholarly journals Isotemporal substitution of inactive time with physical activity and time in bed: cross-sectional associations with cardiometabolic health in the PREDIMED-Plus study

2019 ◽  
Vol 16 (1) ◽  
Author(s):  
Aina M. Galmes-Panades ◽  
Veronica Varela-Mato ◽  
Jadwiga Konieczna ◽  
Julia Wärnberg ◽  
Miguel Ángel Martínez-González ◽  
...  
Keyword(s):  
Physical Activity ◽  
Blood Pressure ◽  
Older Adults ◽  
Metabolic Syndrome ◽  
Body Composition ◽  
Waist Circumference ◽  
Biochemical Parameters ◽  
Cross Sectional ◽  
The Metabolic Syndrome ◽  
Time In Bed

Abstract Background This study explored the association between inactive time and measures of adiposity, clinical parameters, obesity, type 2 diabetes and metabolic syndrome components. It further examined the impact of reallocating inactive time to time in bed, light physical activity (LPA) or moderate-to-vigorous physical activity (MVPA) on cardio-metabolic risk factors, including measures of adiposity and body composition, biochemical parameters and blood pressure in older adults. Methods This is a cross-sectional analysis of baseline data from 2189 Caucasian men and women (age 55–75 years, BMI 27–40 Kg/m2) from the PREDIMED-Plus study (http://www.predimedplus.com/). All participants had ≥3 components of the metabolic syndrome. Inactive time, physical activity and time in bed were objectively determined using triaxial accelerometers GENEActiv during 7 days (ActivInsights Ltd., Kimbolton, United Kingdom). Multiple adjusted linear and logistic regression models were used. Isotemporal substitution regression modelling was performed to assess the relationship of replacing the amount of time spent in one activity for another, on each outcome, including measures of adiposity and body composition, biochemical parameters and blood pressure in older adults. Results Inactive time was associated with indicators of obesity and the metabolic syndrome. Reallocating 30 min per day of inactive time to 30 min per day of time in bed was associated with lower BMI, waist circumference and glycated hemoglobin (HbA1c) (all p-values < 0.05). Reallocating 30 min per day of inactive time with 30 min per day of LPA or MVPA was associated with lower BMI, waist circumference, total fat, visceral adipose tissue, HbA1c, glucose, triglycerides, and higher body muscle mass and HDL cholesterol (all p-values < 0.05). Conclusions Inactive time was associated with a poor cardio-metabolic profile. Isotemporal substitution of inactive time with MVPA and LPA or time in bed could have beneficial impact on cardio-metabolic health. Trial registration The trial was registered at the International Standard Randomized Controlled Trial (ISRCTN: http://www.isrctn.com/ISRCTN89898870) with number 89898870 and registration date of 24 July 2014, retrospectively registered.

Abstract P298: Progression Of Subclinical Atherosclerosis And Its Determinants In Early Postmenopausal Chinese Women - A Five-year Followup Study Of A Population-based Cohort

Circulation ◽  
2012 ◽  
Vol 125 (suppl_10) ◽  
Author(s):  
Suzanne Ho (Chan) ◽  
Ruby HY Yu ◽  
Stella Ho ◽  
Sophie SG Chan ◽  
Jean LF Woo ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Waist Circumference ◽  
Postmenopausal Women ◽  
Chinese Women ◽  
Subclinical Atherosclerosis ◽  
Fruit Intake ◽  
Plaque Progression ◽  
Early Postmenopausal Women ◽  
Normal Ranges ◽  
Linear Probe

Introduction: Subclinical atherosclerosis (SA) progresses silently over a period of time before the clinical manifestations of cardiovascular disease. Hypothesis: We hypothesize that early postmenopausal women with adverse cardiovascular risk factors or their progression to abnormal values have a higher risk of SA. This study aimed to investigate the progression of SA and its determinants in early postmenopausal Chinese women. Methods: This is a community-based 5-year followup study on a cohort of 518 women aged 50–64, within 10 years menopause, and recruited through random telephone dialing. Clinical assessments, fasting blood samples, lifestyle and dietary variables based on validated and structured questionnaires, as well as intima-media thickness (IMT) were obtained at baseline and at followup. IMT was measured using a 12.5-MHz linear probe of the HDI 5000 ultrasound scanner at the near and far walls of three 10-mm segments: distal common carotid, bifurcation, proximal internal carotid of both the left and right carotid arteries. Plaque was defined as a focal wall thickening of at least 1.5mm and graded as: grade 0, 1 and 2. Plaque progression was the difference of the plaque index at baseline and followup, and classified into 3 categories. Results: This study of Chinese early postmenopausal women (followup mean age 61.5 years at followup) has revealed a progression of IMT of 2.1% per year (standard deviation = 1.7). 17% were found to have a moderate and 8% severe plaque progression. Stepwise multiple regression analyses showed that baseline IMT, age, low density lipoprotein cholesterol (LDL-C), systolic and diastolic blood pressure were significant predictors of higher followup IMT, while vegetable and fruit intake were inversely related. Women with values belonging to the “normal” ranges of blood pressure, waist circumference, lipid and fasting blood glucose levels had lower IMT at followup compared to those with abnormal baseline values and those with progression from “normal” to the “abnormal” ranges. Women with high soy-vegetable-fruit intake at both baseline and followup had lower IMT than those with low intakes at both time points. Increasing age, waist circumference ≥80 cm, cholesterol ≥200 mg/L, having diabetes, regular drinking were significant predictors of plaque progression (adjusted odds ratios from 1.10 to 2.81), while higher vegetable and fruit intake lowered the risk. Conclusion: Age, central obesity, diabetes, dislipidaemia, high blood pressure, regular drinking were significant predictors for an increased risk of SA. Maintenance of these CVD factors within normal ranges through early menopausal years with adequate fruit and vegetable intake is important to reduce the progression of SA.

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