scholarly journals USAGE OF METABOLISM ENERGY IN FORMATION OF BODY THERMAL STATE OF THE CATTLE

2021 ◽  
Vol 250 ◽  
pp. 234-242
Author(s):  
B.P. Mokhov ◽  
Keyword(s):  
Biological Sciences ◽  
Thermal State ◽  
Weather Conditions ◽  
The Body ◽  
Metabolic Energy ◽  
Electrochemical Reactions ◽  
Heat Sources ◽  
Discrete Heat Sources ◽  
Intracellular Metabolism ◽  
New Compounds

Scientific advances in biological sciences make it possible to significantly increase the energy efficiency of productive livestock. For life, as the highest form of existence of matter, thermal energy is of particular importance. It does not only connect the actions and interactions of all types of matter, it creates order from the chaotic movements of discrete heat sources, determining the measure of irreversible energy dissipation (entropy) and the change gradient of metabolic processes, “outflow and inflow of energy”, the state of saturation and deficiency of nutrients in the body. Metabolic energy is the energy of nutrients entering the tissues and cells of the body from the digestive tract. In the process of intracellular metabolism, substances are converted into new compounds, energy is released and accumulated. Approximately half of the energy is used in the electrochemical reactions of the synthesis of substances inherent in this organism. Heredity, age, environment, condition of animals influence their quantity and quality. The second half of the energy generated in the basic metabolism is “dissipated” and released into the internal and external environment. This part of the energy, in the thermoregulation process, provides isothermal state of the body of animals. Thermal homeostasis, the range of fluctuations in body temperature within the physiological norm is a significant part of the metabolic energy consumption. The article presents results of studying such consumptions when adapting to feeding factors and changes of weather conditions of cattle of different age and productivity.

Indicators of metabolism and biochemical status of blood in horses of Yakut breed in winter and spring seasons

2020 ◽  
pp. 52-65
Author(s):  
U. Khompodoeva ◽  
R. Ivanov
Keyword(s):  
Classical Method ◽  
Live Weight ◽  
Weather Conditions ◽  
The Body ◽  
Metabolic Energy ◽  
Temperature Changes ◽  
Experimental Animals ◽  
Spring Period ◽  
Biochemical Status ◽  
Adaptive Mechanisms

The results of researches on the peculiarities of metabolism in the body of horses of Yakut breed in the winter and spring periods under the environments of Central Yakutia have been presented in the article. Physiological experiments on the digestibility of the main nutrients of the feed have been carried out in the winter (February) and spring (April) periods under the environments of the physiological yard in the Yakutsk Scientific and Research Institute of Agriculture named after M. G. Safronov with using the classical method. Five mares and five geldings of Yakut breed have been selected for researches. The average live weight of mares was 378–410 kg, geldings 394–403 kg. The experimental animals had average fatness. It has been found a higher intake of energy and the main nutrients of hay as a mono feed in winter compared to the spring period. At the same time pregnant mares in winter have been consumed 103,8±3,12 MJ of metabolic energy per head/day, which was 27,3 % significantly higher than in the spring period – 75,4±2,18 MJ (P ≥ 0,999). Geldings have been consumed in the experiment 67,70±2,85 MJ, which was by 43,7 % higher than in the spring period – 38,05 ± 4,40 MJ of metabolic energy per head/day (P ≥ 0,999). Experimental animals have been housed in stalls; there was no energy expenditure for movement, so the amount of energy consumed in winter indicates the production of heat in the animal’s body. Pregnant mares per 100 kg of live weight have consumed 31,5±4,11 MJ of metabolic energy or 33,3 % more than in the spring period – 21,0±1,98 MJ; geldings have consumed 27,69±1,12, which was 41,78 % significantly higher than in the spring – 16,12 ± 0,75 MJ (P ≥ 0,999). The high intake of metabolic energy into the body of Yakut horses in winter is explained by the manifestation of adaptive mechanisms that affect the effective metabolism for survival, adapted to frequent changes in weather conditions and sharp temperature changes. The established differences in the biochemical parameters of blood serum of horses of Yakut breed are associated with changes in the consumption and digestibility of basic nutrients and energy, depending on the ambient temperature.

The use of acidifying agents Aquasafe and Veleguard when rearing of broiler chickens

2020 ◽  
pp. 16-27
Author(s):  
L. Gamko ◽  
T. Tarinskaya
Keyword(s):  
Drinking Water ◽  
Organic Acids ◽  
Broiler Chickens ◽  
Positive Impact ◽  
The Body ◽  
Metabolic Energy ◽  
Control Group ◽  
Meat Production ◽  
Feed Conversion ◽  
Broiler Meat

It is known that necessary to replace the components of organic acids, which are part of acidifiers when drinking water to poultry in order to prevent the adaptation of microbes in the gastrointestinal tract. In the poultry industry organic acids are widely used, which are used as acidifiers to preserve the properties of water consumed. The purpose of this work was to evaluate the efficiency of broiler meat production when using acidifying agents of drinking water Aquasafe and Veleguard. The experimental part of the work has been performed in JSC “Kurinoe Tsarstvo-Bryansk” broiler area “Roshcha” in the Pochepsky district. The object of research was the livestock of broiler chickens cross Cobb 500 at floor housing. The effect of water acidifiers on meat productivity has been studied. Groups of chickens have been formed on the principle of pairs-analogues. Broiler chickens of experimental groups have been separated from the main livestock by a grid in the corner of the room for 100 heads in each group. It has been found by a result of research to be optimal dose usage of acidifying agents water Aquasafe and Veleguard to drink to broiler chickens. The positive effect of these acidifiers on the digestion of crude protein, crude fat, crude fiber, contributing to the effective use of nitrogen, which led to an increase in the intensity of growth, young animals’ livability and improved feed conversion. Slaughter yield in the control group was 55,1 %, and in the experimental group 57,2 and 58,4 %, which was by 2,1 and 3,3 % higher with the same level of metabolic energy and nutrients. In chickens that consumed acidifi ers more intensively used nutrients feed for deposition in the body of the components of the carcass, which affected the production. A positive impact of acidifying agents Aquasafe and Veleguard on meat quality in broiler chickens has been found.

Design, Synthesis and Antitumor Assessment of Phenylureas Bearing 5-Fluoroindolin-2-one Moiety

2020 ◽  
Vol 16 (7) ◽  
pp. 958-968
Author(s):  
Yunrui Cai ◽  
Tong Chen ◽  
Huajian Zhu ◽  
Hongbin Zou
Keyword(s):  
Breast Cancer ◽  
Human Breast Cancer ◽  
Human Cancer ◽  
The Body ◽  
Human Breast ◽  
Design Synthesis ◽  
Human Carcinoma ◽  
Xenograft Models ◽  
New Compounds ◽  
Mcf 7

Background: The development of novel antineoplastic agents remains highly desirable. Objective: This study focuses on the design, synthesis, and antitumor evaluation of phenyl ureas bearing 5-fluoroindolin-2-one moiety. Methods: Three sets of phenylureas were designed and synthesized and their antiproliferative ability was measured against four human carcinoma cell lines (Hela, Eca-109, A549, and MCF-7) via MTT assay. In vivo anticancer activity was further evaluated in xenograft models of human breast cancer (MCF-7). Results: A total of twenty-one new compounds were synthesized and characterized by means of 1H and 13C NMR as well as HR-MS. Three sets of compounds (1a‒1c, 2a‒2c, and 3a‒3c) were initially constructed, and preliminary antiproliferative activities of these molecules were evaluated against Hela, Eca-109, A549 and MCF-7, highlighting the meta-substituted phenylureas (1a‒1c) as the most cytotoxic set. A series of meta-substituted phenylureas derivatives (1d‒1o) were then designed and synthesized for structure-activity relationship study. Most of the new compounds showed desirable cytotoxicity, among which compound 1g exhibited the most remarkable cytotoxic effects against the tested human cancer cells with IC50 values ranging from 1.47 to 6.79 μM. Further studies showed that compound 1g suppressed tumor growth in human breast cancer (MCF- 7) xenograft models without affecting the body weight of its recipients. Conclusion: In this study, twenty-one new compounds, containing the privileged structures of phenylurea and 5-fluoroindolin-2-one, were designed and synthesized. Subsequent structureactivity studies showed that 1g was the most bioactive antitumor agent among all tested compounds, hence a potentially promising lead compound once given further optimization.

Health indicators of children 10-11 years old at physical education lessons (cycling module)

2021 ◽  
pp. 113-116
Author(s):  
Maryna Prudnikova ◽  
Katerina Mulik
Keyword(s):  
Physical Education ◽  
Physical Fitness ◽  
Health Indicators ◽  
Weather Conditions ◽  
The Body ◽  
Main Role ◽  
Number Of Children ◽  
Grade 5 ◽  
The Future ◽  
Demographic Processes

The future of Ukraine is children, the future of demographic processes largely depends on their number, their health. The main role in the child's life is played by the dynamic process of growth and biological maturation, where one of the informative indicators is the cardiovascular system. In case of severe discomfort in the body, it is necessary to stop classes and consult a doctor. All physical activity must correspond to the physical fitness and age of the children. The cycling module is designed for 24 hours, according to the schedule, two physical education lessons were paired. For an effective lesson. In the course of the lessons, they mastered theoretical information (10 %), general and special physical training (20 %), technical training (70 %). During physical culture classes using a bicycle, objective factors were taken into account, such as the availability of a sports ground for technical riding, equipment (30 bicycles), and the weather conditions of the region. Over the course of one and a half months, the conducted classes formed the necessary skills for safe cycling, technical skill in children of 10-11 years old, provided the necessary foundation for physical fitness and motivation to go in for sports. The increase in adaptive indices of the heart was 14 % in grade 5-A, 8 % in grade 5-B, and 15 % in grade 5-V of the total number of children in each grade. This indicates that muscular work took place with positive consequences for the functional state of the body of children aged 10-11 years.

Transient Temperature Involving Oscillatory Heat Source With Application in Fretting Contact

2007 ◽  
Vol 129 (3) ◽  
pp. 517-527 ◽  
Author(s):  
Jun Wen ◽  
M. M. Khonsari
Keyword(s):  
Heat Source ◽  
Oscillation Amplitude ◽  
The Body ◽  
Transient Temperature ◽  
Dimensionless Frequency ◽  
Heat Sources ◽  
Infinite Body ◽  
Fitting Method ◽  
Wide Range ◽  
Analytical Expressions

An analytical approach for treating problems involving oscillatory heat source is presented. The transient temperature profile involving circular, rectangular, and parabolic heat sources undergoing oscillatory motion on a semi-infinite body is determined by integrating the instantaneous solution for a point heat source throughout the area where the heat source acts with an assumption that the body takes all the heat. An efficient algorithm for solving the governing equations is developed. The results of a series simulations are presented, covering a wide range of operating parameters including a new dimensionless frequency ω¯=ωl2∕4α and the dimensionless oscillation amplitude A¯=A∕l, whose product can be interpreted as the Peclet number involving oscillatory heat source, Pe=ω¯A¯. Application of the present method to fretting contact is presented. The predicted temperature is in good agreement with published literature. Furthermore, analytical expressions for predicting the maximum surface temperature for different heat sources are provided by a surface-fitting method based on an extensive number of simulations.

scholarly journals Elastic energy savings and active energy cost in a simple model of running

2021 ◽  
Vol 17 (11) ◽  
pp. e1009608
Author(s):  
Ryan T. Schroeder ◽  
Arthur D. Kuo
Keyword(s):  
Elastic Energy ◽  
Energy Cost ◽  
Energy Savings ◽  
Mechanical Energy ◽  
Metabolic Cost ◽  
The Body ◽  
Metabolic Energy ◽  
Energetic Cost ◽  
Mass Model ◽  
Human Running

The energetic economy of running benefits from tendon and other tissues that store and return elastic energy, thus saving muscles from costly mechanical work. The classic “Spring-mass” computational model successfully explains the forces, displacements and mechanical power of running, as the outcome of dynamical interactions between the body center of mass and a purely elastic spring for the leg. However, the Spring-mass model does not include active muscles and cannot explain the metabolic energy cost of running, whether on level ground or on a slope. Here we add explicit actuation and dissipation to the Spring-mass model, and show how they explain substantial active (and thus costly) work during human running, and much of the associated energetic cost. Dissipation is modeled as modest energy losses (5% of total mechanical energy for running at 3 m s-1) from hysteresis and foot-ground collisions, that must be restored by active work each step. Even with substantial elastic energy return (59% of positive work, comparable to empirical observations), the active work could account for most of the metabolic cost of human running (about 68%, assuming human-like muscle efficiency). We also introduce a previously unappreciated energetic cost for rapid production of force, that helps explain the relatively smooth ground reaction forces of running, and why muscles might also actively perform negative work. With both work and rapid force costs, the model reproduces the energetics of human running at a range of speeds on level ground and on slopes. Although elastic return is key to energy savings, there are still losses that require restorative muscle work, which can cost substantial energy during running.

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