scholarly journals Nutritional status disorders in women with lichen sclerosus of the vulva

2021 ◽  
pp. 75-79
Author(s):  
V.V. Dunaievska ◽  
E.H. Manzhalii

Research objective: to determine the characteristics of nutritional status (NS) in women of reproductive age with typical clinical signs of lichen sclerosus of the vulva (LSV) using key NS parameters. Materials and methods. The study included 75 women with average age 31.3 ± 1.3 years. 50 women were diagnosed with LSV and NS disorders (main group), and 25 women were practically healthy (control group). Information about all patients was collected through direct interviews, clinical examination and study of medical records. The presence of anogenital pruritus, soreness or burning, dryness, dyspareunia, urinary disturbances, perianal and/or intestinal symptoms, inflammatory bowel disease, thyroid dysfunction and tenderness, and other comorbidities were recorded. NS evaluated using anthropometric, laboratory and clinical studies. Body mass index, index of nutritional risk (nutritional deficiency), vitamins, micro- and macroelements value, scatological parameters were determined in all patients, and the intestinal microflora was examined.Results. The results of the study showed a disorder of NS in most patients with LSV by all studied parameters in comparison with the control group. Thus, it was found that 60% of patients with LSV had abnormal body mass index as well as NS was observed in 72% of patients. In addition, patients with LSV also had a higher deficiency of vitamins D and B12, and some important micro- and macronutrients. The results of the coprological study showed the neutral fats in feces, unchanged muscle fibers, extracellular and intracellular starch, decreased levels of bifidobacteria and lactobacilli in 68–74% of patients and opportunistic bacteria and fungi in 30–46% of women in the main group.Conclusions. Thus, the results of this study indicate the association between the abnormal NS and LSV. However, further research is needed to assess the course of the underlying disease and to analyze the metabolic pathways that lead to disorders of lipid, carbohydrate and protein metabolism in target patients, to select of the correct nutrients and alternative treatments.

2020 ◽  
Vol 10 (2) ◽  
pp. 173-180
Author(s):  
Teti Tejayanti

Abstrak   Latar belakang:  Status  gizi  perempuan  di  Indonesia  cenderung  memburuk.  Hasil  Riset  Kesehatan  Dasar (Riskesdas) menunjukkan bahwa kekurangan energi kronis (KEK) pada wanita usia reproduksi meningkat dari 13,6 persen pada 2007 menjadi 20,8 persen pada 2013. Ibu hamil yang kekurangan gizi akan berdampak buruk pada bayinya. Tujuan: Memperoleh determinan status gizi kurang yaitu KEK dan Indeks Massa Tubuh (IMT) rendah dari wanita hamil di Indonesia pada tahun 2013. Metode: Penelitian menggunakan data Riskesdas 2013. Analisis dilakukan dengan multivariat regresi logistik. Jumlah sampel adalah 7236 ibu hamil. Ibu hamil dikatakan KEK jika pertengahan lingkar lengan atas (LILA) < 23,5 cm dan IMT diukur dengan pendekatan metode Broca. Hasil: Determinan ibu hamil KEK dan IMT rendah adalah tinggal di perdesaan (AOR 1,20; 95% CI [1,11-1,13]), usia <20 tahun (AOR 1,62; 95% CI [1,60-1,65]), paritas 1 anak (AOR 2,04; 95% CI [2,02-2,06]), berpendidikan rendah (AOR 1,92; 95% CI [0,91-0,93]) dan status ekonomi rendah (AOR 3,36; 95% CI [3,31- 3,41]). Kesimpulan: Pendidikan harus ditingkatkan minimal hingga sekolah menengah atas sehingga pengetahuan gizi ibu meningkat dan kehamilan dini dapat dicegah. Ibu dengan status ekonomi rendah harus menjadi prioritas dalam pelayanan ibu dan upaya intervensi gizi.   Kata kunci: Sosial ekonomi, lingkar lengan atas, KEK, BMI, gizi ibu hamil.     Abstract   Background: The nutritional status of women in Indonesia tends to worsen. Basic Health Research (Riskesdas) showed that chronic energy deficiency (CED) among women of reproductive age increased from 13.6 percent in 2007 to 20.8 percent in 2013. Pregnant women who are lack of nutrition will have an impact on their babies. Objective: To determine the determinants of poor nutritional status which are CED and low body mass index (BMI) of pregnant women in Indonesia. Method: This study used 2013 Riskesdas data. The analysis was done using multivariate logistic regression. The total  sample  was 7236  pregnant  women.  Pregnant  women  with CED are those who  have mid-upper  arm circumference (MUAC) of less than 23.5 cm and BMI was measured by the Broca method approach. Results: The determinants of pregnant women with CED and low BMI are living in rural area (AOR 1.20; 95% CI [1.11-1.13]), age of <20 years (AOR 1.62; 95% CI [1.60-1.65]), having 1 child (AOR 2.04; 95% CI [2.02- 2.06]), having low education (AOR 1.92; 95% CI [0.91-0.93]) and low economic status (AOR 3.36; 95% CI [3.31- 3.41]). Conclusion: Education must be improved to at least high school degree, so that the mother's nutritional knowledge will increase, and early pregnancy will be prevented. Mothers with low economic status must be priority in maternal cervices and nutrition interventions.   Keywords: Socioeconomic, nutrition, mid-upper arm, CED, BMI, nutrition of pregnant women


2019 ◽  
pp. 22-28
Author(s):  
V. M. Nedoborenko ◽  
I. P. Kaidashev

Iron deficiency anemia (IDA) is one of the causes of chronic fatigue with a decrease in the quality of life, impaired cognitive function and poor labor productivity. Obesity as a condition of chronic low-intensity inflammation is one of the factors that increases the risk of anemia and impairs the quality of life in the general population. We drew attention to the high global prevalence of anemia among pregnant women of reproductive age in the world and the prevalence of high body mass index among women compared to men in most countries. The objective of the work was to determine the impact of obesity on clinical features and quality of life of women with ІDA. We analyzed the main markers of ІDA and hematologic indices in women with obesity (n = 30) compared with the control group (n = 10), where there were women with ІDA but without obesity. It was found that there was no statistical difference between these parameters, but nevertheless, the serum ferritin level in obese women was (4.70 ± 2.68) ng/ml compared to (3.50 ± 2.93) ng/ml and had a significant positive correlation with body mass index. The analysis of the questionnaires revealed that obesity is still a significant factor in women with ІDA and obesity, which determines the decrease in quality of life mainly in the physical aspect in the absence of significant influence on the psychosocial components of health.


2001 ◽  
Vol 11 (3) ◽  
pp. 229-236 ◽  
Author(s):  
Yee Kiat Teo ◽  
HA Wynne

Dietary, biochemical and anthropometric data indicate good nutritional status, in general, in community-dwelling, healthy elderly people, at least in the USA. In a sample of 209 men over 65 years of age without acute disease-related nutritional risk factors, mean intake of nutrients generally met or exceeded the recommended dietary values, with the exception of calories, although 7% of subjects consumed inadequate amounts of thiamine, vitamin A, vitamin C and calcium. Few subjects were extremely underweight or obese, although body fat, as assessed by skinfold thickness, fell over the two years of evaluation. The prevalence of malnutrition in patients with chronic disease living in the community in the UK is estimated to be around 8%, however. In this study of more than 11 000 men and women aged 18 years or over, consultation rates in general practice and prescription rates were lowest amongst patients with a body-mass index between 20 and 25. Hospital outpatient referral rates were not related to nutritional status, but both hospital admission rates and mortality were greatest in people with a body-mass index(BMI) (kg/m2) below 20, and declined as BMI increased.


Author(s):  
S shanthi ◽  
. Shambhavi

Introduction: Nutritional issues are typically encountered throughout the treatment of cancer. Cancer cachexia is usually recognised as not only reduced bodily function and quality of life, but also poor positive outcome in patients. Naturally, Body Mass Index (BMI) is frequently used for determining nutritional status of a patient. Intervening nutritional problems of the patient leads to better prognosis. It is necessary to identify patients at-risk earlier and provide effective nutritional interventions. Aim: To determine the level of BMI and evaluate the effect of nutritional therapy on BMI and find its association with demographic characteristics. Materials and Methods: This was a quasi-experimental interventional trial conducted among 100 patients admitted in the hospital with a diagnosis of head, neck and breast cancers. Parameters assessed were baseline proforma, weight and height which were measured and BMI was calculated (BMI=kg/m2 in which kg is a individuals weight in kilograms and m2 is their height in meters squared) and classified as per World Health Organisation (WHO) guidelines. Results: Before nutritional intervention 20% and 26% of patients were underweight in the experimental and control group respectively, whereas after 21 days 18% in experimental and 32% in control were underweight. Z score for post-test level of BMI in the experimental and control group were 2.125 and 2.34, respectively is greater than the tabulated value (Z=1.96 at p-value=0.05 level of significance), hence there was a significant difference between post-test level of BMI in the experimental and control group. High protein high caloric whole food was significant. Conclusion: Investigators concluded from the present study that nutrition therapy can help to maintain or improve the nutritional status among patients on cancer treatment.


Author(s):  
Adygezalova KP ◽  
◽  
Gurbanova JF ◽  

Menstrual irregularities of the oligomenorrhea type may depend on the presence or absence of hormonal or metabolic disorders. Antiovarian antibodies to the ovaries (AOA) can be one of the causes of hormonal disorders and related menstrual disorders. The aim of the study was to assess the functional state of the ovaries in women with oligomenorrhea and to compare the presence of antiovarian antibodies (AOA) with a group of healthy fertile women. Material and Methods: 105 patients of reproductive age with oligomenorrhea were examined. Control - 50 women of childbearing age with an undisturbed rhythm of menstruation. Body mass index was calculated, ultrasound was performed, LH, FSH, estradiol, total testosterone by immunochemiluminescent method, anti-Müllerian hormone (AMH) by ELISA, AOA by ELISA method were determined. Statistica software (Stat Soft, USA) was used for statistical analysis. Results: The average age of patients with oligomenorrhea and the control group was 31.39 ± 6.05 and 30.52 ± 5.92 years. Body mass index averaged 25.59 ± 2.74 and 24.12 ± 2.77 kg / m2 , respectively, in the main and control groups. The volume of the ovaries in the main group was 13.22 ± 3.01, in the control group - 6.0 ± 1.26 (p = 0.028), the width of the stroma in the main group was 16.46 ± 3.25 mm, in the control group - 8.97 ± 1.16 mm (p = 0.031). The average LH level in women with oligomenorrhea was 51.75% higher than the control level (p = 0.048), the LH / FSH ratio was higher by 44.28% (p = 0.007), and the AMH value was higher by 33.86% (p = 0.048). The AOA level in the main group averaged 6.36 ± 1.14 ng / ml, in the control group - 3.06 ± 1.16 ng / ml (p = 0.044). In patients with oligomenorrhea, AOA correlated with all studied hormones by a statistically significant relationship, and a significant relationship was determined with the level of LH, AMH and estradiol. In contrast to the main group, in women with a normal menstrual cycle, AOA was correlated with a significant significant association with FSH, total testosterone, and a weak insignificant association with LH. Conclusion: In women of reproductive age with oligomenorrhea, high levels of LH, AMH, LH / FSH and antiovarian antibodies are determined. Antiovarian antibodies to the ovaries in oligomenorrhea correlate with a direct, noticeable relationship with gonadotropic and steroid hormones. To identify the autoimmune process in patients with oligomenorrhea, it is necessary to determine antiovarian antibodies.


2016 ◽  
pp. 191-108
Author(s):  
A.A. Sukhanova ◽  
◽  
Yu.M. Melnik ◽  
O.O. Karlova ◽  
◽  
...  

The aim of the study: to study the efficacy and safety of use Mastofemin in the treatment of various forms of mastitis in women of reproductive age. Materials and methods. The study included 62 women of reproductive age (mean age of 33.5±2.3 years) who were screened in the Kiev city center reproductive and perinatal medicine. Women were divided into 2 groups. The first (main) group consisted of 32 patients who received the proposed treatment using herbal remedies Mastofemin 1 capsule 2 times per day for 3 months; 30 patients of the second (control) group were under observation and received no treatment. These groups were representative and homogeneous on age, clinical symptoms and sonographic characteristics. The clinical method included evaluation of complaints of patients, anamnesis, presence of concomitant gynecologic pathology, inspection, palpation of the lymph nodes and the breast and obtaining a discharge from the nipples to conduct cytological examination, which allowed excluding from the study women with suspected malignancy of the process. All the patients were performed ultrasound examination of the breast. The review was supplemented with vaginal gynecological examination and ultrasound examination of small pelvis organs to assess the condition of the uterus and its appendages, the diagnosis of gynecological diseases. Results. Summarizing obtained in this study results one should stress the positive long-term effect of applying Mastofemin for the treatment of proliferative changes of the breast in women of reproductive age. This is manifested by a decrease in the intensity of clinical signs of mastitis, consistent with the results of sonographic control. Established positive dynamics in the treatment of cystic mastitis, dectective and when combined cystic mastopathy with dectective. In the control group of patients for a given observation period (6 months) no significant changes in clinical signs of mastitis and sonographic characteristics. Regression of disease has not occurred in any of the patients, in 2 patients increased sensitivity of the breast after 6 months moved to the soreness. Sonographic characteristics of mastitis during the observation period did not change. Thus, the use of Mastofemin aimed at pathogenetic treatment of mastitis and prevention of breast cancer. Conclusion. Application of Mastofemin during the treatment of mastitis in women of reproductive age significantly improves the clinical condition of patients; reduce the subjective and objective symptoms of the disease. The positive effect of the treatment with Mastofemin proved in the case of the treatment of sonographic following forms of mastitis: cystic mastopathy, cystic mastopathy with dectectasy. Mastofemin may be the drug of choice for complex conservative monotherapy in women of reproductive age with proliferative changes in the breast, and can also be used as part of complex treatment in patients with diffuse changes of the breast when combined with hyperplastic processes of the myometrium and endometrium. Keywords: mastopathy, breast gland, herbal medicine, herbal remedies, Mastofemin.


2013 ◽  
Vol 32 (1) ◽  
pp. 26-31 ◽  
Author(s):  
Emina Čolak ◽  
Dragana Pap ◽  
Nada Majkić-Singh ◽  
Ivana Obradović

Summary Background: It has been reported that obesity is associated with metabolic syndrome, insulin resistance, cardiovascular risk but also with nonalcoholic fatty liver disease (NAFLD). The prevalence of obesity in children and adolescents is increasing rapidly all over the world. The aim of this study was to analyze the value of liver enzymes: AST, ALT and γGT in a group of obese students in order to establish their correlation to anthropometric parameters such as: BMI (body mass index), WC (waist circumference), HC (hip circumference), and WHR (waist-to-hip ratio) compared to non-obese students who comprised the control group (CG). Methods: In this study, 238 students from the University of Novi Sad of both sexes (126 men and 112 women) with a mean age of 22.32 ± 1.85 years were included. According to the body mass index (BMI) lower and higher than 25 kg/m2 and waist circumference (WC) lower and higher than 94 cm (80 cm for females) the whole group of 238 students was divided into 2 subgroups: the obese group at increased risk for CVD (Group 1) and the group at lower risk for CVD (Group 2). AST, ALT and γGT activities were determined in fasting blood samples. Results: Statistical processing data revealed significantly higher values of AST, ALT and γGT in the group of students with BMI>25 kg/m2, WC>94 cm for males and WC>80 cm for females, HC>108 cm for males and HC>111 cm for females, and WHR>0.90 for males and WHR>0.80 for females (P<0.001). Significant association was established between anthropometric parameters and liver enzyme levels (P<0.0001). Conclusions: Obese students with higher BMI, WC, HC and WHR values have higher liver enzyme activites and a higher chance to develop NAFLD in the future.


2021 ◽  
Vol 10 (13) ◽  
pp. 2811
Author(s):  
Katarzyna Ożegowska ◽  
Szymon Plewa ◽  
Urszula Mantaj ◽  
Leszek Pawelczyk ◽  
Jan Matysiak

Polycystic ovary syndrome (PCOS) is the most prevalent endocrine and metabolic disorder, affecting 5–10% of women of reproductive age. It results from complex environmental factors, genetic predisposition, hyperinsulinemia, hormonal imbalance, neuroendocrine abnormalities, chronic inflammation, and autoimmune disorders. PCOS impacts menstrual regularities, fertility, and dermatological complications, and may induce metabolic disturbances, diabetes, and coronary heart disease. Comprehensive metabolic profiling of patients with PCOS may be a big step in understanding and treating the disease. The study aimed to search for potential differences in metabolites concentrations among women with PCOS according to different body mass index (BMI) in comparison to healthy controls. We used broad-spectrum targeted metabolomics to evaluate metabolites’ serum concentrations in PCOS patients and compared them with healthy controls. The measurements were performed using high-performance liquid chromatography coupled with the triple quadrupole tandem mass spectrometry technique, which has highly selective multiple reaction monitoring modes. The main differences were found in glycerophospholipid concentrations, with no specific tendency to up-or down-regulation. Insulin resistance and elevated body weight influence acylcarnitine C2 levels more than PCOS itself. Sphingomyelin (SM) C18:1 should be more intensively observed and examined in future studies and maybe serve as one of the PCOS biomarkers. No significant correlations were observed between anthropometric and hormonal parameters and metabolome results.


2020 ◽  
Vol 40 ◽  
pp. 550-551
Author(s):  
E. Cereda ◽  
F. Lobascio ◽  
S. Masi ◽  
S. Crotti ◽  
S. Cappello ◽  
...  

2011 ◽  
Vol 2011 ◽  
pp. 1-4
Author(s):  
Subal Das ◽  
Kaushik Bose

A community-based cross-sectional study was undertaken to determine the prevalence of undernutrition using body mass index (BMI) among 2–6-year Santal preschool children of Purulia District, West Bengal, India. A total of 251 (116 boys and 135 girls) children from 12 villages were measured. Commonly used indicators, that is, weight, height, and BMI, were used to evaluate the nutritional status. More boys (59.5%) than girls (53.3%), based on BMI, were undernourished. Significant age differences in weight (F=44.29∗∗∗; df=3), height (F=58.48∗∗∗; df=3), and BMI (F=3.52∗∗∗; df=3) among boys were observed. Similarly, significant differences between ages in mean weight (F=56.27∗∗∗; df=3), height (F=64.76∗∗∗; df=3), and BMI (F=2.62∗∗∗; df=3) were observed among the girls. The present study revealed that the nutritional status of the preschool children of Santal tribal community of these villages was poor with very high rate of thinness in boys and girls (59.5% and 53.3%, resp.).


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