scholarly journals Morfometri Limpa Berkaitan dengan Produksi Radikal Bebas dan Antioksidan pada Kelelawar Pemakan Buah Codot Krawar (Cynopterus brachyotis)

2018 ◽  
Vol 19 (1) ◽  
pp. 62 ◽  
Author(s):  
Desrayni Hanadhita ◽  
Andhika Yudha Prawira ◽  
Anisa Rahma ◽  
Aryani Sismin Satyaningtijas ◽  
Srihadi Agungpriyono
Keyword(s):  
Negative Impact ◽  
Physiological State ◽  
Genetic Material ◽  
Lymphoid Organ ◽  
Viral Reservoir ◽  
Ros Generation ◽  
Fruit Bats ◽  
Immune Activity ◽  
High Level ◽  
Cynopterus Brachyotis

Fruit bats have been reported as the natural reservoir of many emerging and re-emerging zoonotic diseases. Infected bats usually do not show any clinical symptoms and are infected persistently. This unique characters indicate that bats have high immune activity to combat viruses even in its physiological state. High immune activity will affect the size of lymphoid organ and produce high level of reactive oxygen species (ROS). Spleen is one of the important lymphoid organ which have a strategic function in elimination of blood borne pathogens. This study was undertaken to provide information on the normal size of spleen and to analyze malonaldehyde (MDA) and super oxide dismutase (SOD) levels of free range fruit bats (Cynopterus brachyotis). The ratio of body weight/spleen was 0.4% and there were no significance differences between the male and female bats. The spleen MDA levels which represent ROS generation was higher than those of the liver. Male bats with higher levels of MDA tend to have bigger spleen size than the female which has lower MDA levels. High levels of MDA might indicate a high immune activity inside the spleen. Despite the negative effect of ROS to genetic material, high level of ROS can be advantageous to support the bats immune system as a viral reservoir. High levels of MDA are generally accompanied by high levels of SOD which might reduce the negative impact of oxidative stress in the C. brachyotis.

INFLUENCE OF HIGH-PROTEIN FEED ADDITIVE ON THE PRODUCTIVITY OF THE MEAT BULL-CALVES

2019 ◽  
Vol 2019 (3) ◽  
pp. 6-11
Author(s):  
Батырхан Абилов ◽  
Batyrkhan Abilov ◽  
Лариса Пашкова ◽  
Larisa Pashkova
Keyword(s):  
Hematological Parameters ◽  
Physiological State ◽  
Average Daily Gain ◽  
Live Weight ◽  
Feed Additive ◽  
North Caucasus ◽  
Agricultural Enterprise ◽  
Bull Calves ◽  
Economic Indices ◽  
High Level

The article presents the data obtained as a result of carrying by employees of the Research Institute of sheep and goat breeding, a branch of the FSBSI "North Caucasus FARC", the scientific and economic experience to study the efficiency of a new fodder additive "Organic" on the productive and physiological indices of bull-calves during the completion of growing in the conditions of the farm "Pata" agricultural enterprise in the Karachay-Cherkessia Republic. The statement of the experience and all researches were carried out according to generally accepted methods. In the course of the experiment, the following indices were studied: the chemical compound of forages, the dynamics of a live weight gain in the experimental stock, hematological parameters, control slaughter data, economic indices. Completed researches have shown positive result from the use of the fodder additive "Organic" in bull-calves diets: an increase in the average daily gain of live weight by 25%, a slaughter yield by 1% and a high level of profitability – 27%. Thus, the additional introduction of "Organic" in a diet of young horned cattle in the 2nd experimental group promoted more intensive metabolism, stabilization of a physiological state, increase in productivity and, as a consequence, profitability of beef production. Researches in this direction reveal the latent fodder reserves promoting increase in the productivity of agricultural animals.

scholarly journals Treatment patterns and appropriateness of antipsychotic prescriptions in patients with schizophrenia

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Verónica Gamón ◽  
Isabel Hurtado ◽  
José Salazar-Fraile ◽  
Gabriel Sanfélix-Gimeno
Keyword(s):  
Negative Impact ◽  
Current Treatment ◽  
Treatment Patterns ◽  
Mental Condition ◽  
Comorbid Condition ◽  
Concomitant Treatment ◽  
Antipsychotic Medications ◽  
Wide Range ◽  
Schizophrenic Patients ◽  
High Level

AbstractSchizophrenia is a chronic mental condition presenting a wide range of symptoms. Although it has a low prevalence compared to other mental conditions, it has a negative impact on social and occupational functions. This study aimed to assess the appropriateness of antipsychotic medications administered to schizophrenic patients and describe current treatment patterns for schizophrenia. A retrospective cohort study was conducted in all patients over the age of 15 with an active diagnosis of schizophrenia and treated with antipsychotics between 2008 and 2013 in the Valencia region. A total of 19,718 patients were eligible for inclusion. The main outcome assessed was inappropriateness of the pharmacotherapeutic management, including polypharmacy use. Altogether, 30.4% of patients received antipsychotic polypharmacy, and 6.8% were prescribed three or more antipsychotics. Overdosage affected 318 individuals (1.6%), and 21.5% used concomitant psychotropics without an associated psychiatric diagnosis. Women and people with a comorbid condition like anxiety or depression were less likely to receive antipsychotic polypharmacy. In contrast, increased polypharmacy was associated with concomitant treatment with other psychoactive drugs, and only in user on maintenance therapy, with more visits to the mental health hospital. Overall, we observed a high level of inappropriateness in antipsychotic prescriptions. Greater adherence to guidelines could maximize the benefits of antipsychotic medications while minimizing risk of adverse effects.

scholarly journals Overview of the Genetic Diversity of African Macrotermes (Termitidae: Macrotermitinae) and Implications for Taxonomy, Ecology and Food Science

Insects ◽  
2021 ◽  
Vol 12 (6) ◽  
pp. 518
Author(s):  
Bronwyn Egan ◽  
Zwannda Nethavhani ◽  
Barbara van Asch
Keyword(s):  
Negative Impact ◽  
Phylogenetic Reconstruction ◽  
Morphological Characters ◽  
Food Science ◽  
Cryptic Diversity ◽  
African Species ◽  
Genetic Groups ◽  
Wide Range ◽  
Coi Sequences ◽  
High Level

Macrotermes termites play important ecological roles and are consumed by many communities as a delicacy and dietary complement throughout Africa. However, lack of reliable morphological characters has hampered studies of Macrotermes diversity in a wide range of scientific fields including ecology, phylogenetics and food science. In order to place our preliminary assessment of the diversity of Macrotermes in South Africa in context, we analysed a comprehensive dataset of COI sequences for African species including new and publicly available data. Phylogenetic reconstruction and estimates of genetic divergence showed a high level of incongruity between species names and genetic groups, as well as several instances of cryptic diversity. We identified three main clades and 17 genetic groups in the dataset. We propose that this structure be used as a background for future surveys of Macrotermes diversity in Africa, thus mitigating the negative impact of the present taxonomic uncertainties in the genus. The new specimens collected in Limpopo fell into four distinct genetic groups, suggesting that the region harbours remarkable Macrotermes diversity relative to other African regions surveyed in previous studies. This work shows that African Macrotermes have been understudied across the continent, and that the genus contains cryptic diversity undetectable by classic taxonomy. Furthermore, these results may inform future taxonomic revisions in Macrotermes, thus contributing to advances in termitology.

Analysis of the state of the migration process of the ukrainian population in the context of domestic and international levels

2021 ◽  
Vol 72 (5) ◽  
pp. 110-118
Author(s):  
M. Shkurat ◽  
K. Pavlotska
Keyword(s):  
Social Protection ◽  
Negative Impact ◽  
Migration Policy ◽  
Cash Flows ◽  
The State ◽  
Negative Consequences ◽  
Migration Process ◽  
State Of The Economy ◽  
Migration Flows ◽  
High Level

Analysis of the migration process of the Ukrainian population, which takes place within the state and at the international level during 2014–2019 is carried out in this paper. On the basis of scientific works of domestic scientists and institutes the problems which have not been investigated, and also aspects which have been solved partially are defined. The negative consequences of the Ukrainian migration process on the state of the country are identified. The classification of migration flows of the Ukrainian population according to the reasons of movement is carried out. The main regions and countries which, as of the beginning of 2021, are more attractive to compatriots and are characterized by significant influxes of Ukrainians are identified. The main centers of departure – regions and countries – which are characterized by high level of outflow of Ukrainians are determined, the main problems and reasons that motivate the outflow of Ukrainians are highlighted in this paper. The level of growth of the Ukrainian population in terms of migration flows is defined. The investigation of Ukrainian diasporas, territorial location and analysis of their share in comparison is carried out. The main factors that force the Ukrainian population to move, which affects the demographic situation in Ukraine, the level of employment, as well as the amount of cash flows to the country and the state of the economy as a whole are identified. The main regulations and identified solutions to the migration flows of the domestic population, which were approved and implemented in the period from 2001 to 2019 are compared in this paper. On the basis of current and newly introduced strategies, critical analysis of the ways of regulating the migration process of the Ukrainian population is carried out, the main aspects and problems of the implemented migration policy of Ukraine are determined. The results of the work are to identify the main ways to reduce the negative impact of the migration process on the country's economy and related processes, and strategies to benefit from the movement of citizens of Ukraine, namely: introduction of intellectual security, revision of wages by region, stimulating the process of attracting technology in all spheres of activity and formation of the social protection system.

CITY PARK AS A NATURAL-ANTHROPOGENIC OBJECT (ON THE EXAMPLE OF THE PARK OF THE 50th ANNIVERSARY OF VLKSM IN THE CITY OF YEKATERINBURG)

2021 ◽  
pp. 133-140
Author(s):  
L. I. ATKINA ◽  
◽  
L. V. BULATOVA ◽  
L. P. ABRAMOVA
Keyword(s):  
Soil Cover ◽  
Negative Impact ◽  
50Th Anniversary ◽  
Ground Cover ◽  
Peat Bogs ◽  
Anthropogenic Transformation ◽  
History Of ◽  
High Level ◽  
The City ◽  
City Park

Based on a comprehensive assessment of the state of the park landscape, the level of its anthropogenic transformation is determined, which is necessary to identify the potential for restoring the natural biodiversity of the object. It is reported that the plantations and soil cover of the park of the 50th anniversary of VLKSM are very heterogeneous; they reflect the history of park establishment. The soil cover consists of three main types: sod, bog and urbanozem. It should be stressed that the best preserved part of the park is the plot with boggy soils around the pond. Herbaceous plants growing on the plot are very similar to the species composition of the ground cover of overgrown peat bogs. Over the 40 years since the foundation of the park, a high level of pollutants has been accumulated in the soil, which allows us to state that the negative impact occurs constantly. Consequently, the existing plantings are insufficient to protect visitors from vehicle emissions from the roads along Yasnaya and Shaumyana streets. There are enough natural elements in the park of the 50th anniversary of VLKSM; this should be taken into account in its redevelopment. There is an opportunity to restore the reservoir and return the plantings to their natural appearance. It is proposed to add elements of landscape decoration in the park.

CRITERIA FOR SELECTION OF PREPARATIONS IN THE DEVELOPMENT OF SORPTION-DETOXIFYING COMPLEXES FOR AGRICULTURAL ANIMALS

2018 ◽  
Vol 1 (2) ◽  
pp. 94-100
Author(s):  
L.L. Zakharova ◽  
◽  
G.A. Zhorov ◽  
V.I. Dorozhkin ◽  
◽  
...  
Keyword(s):  
Chemical Nature ◽  
Negative Impact ◽  
Physiological State ◽  
Animal Husbandry ◽  
Biologically Active ◽  
Combined Pollution ◽  
Wide Range ◽  
Active Substances ◽  
Criteria For Selection ◽  
Selection Of

Negative impact on the environment as a result of economic activity of man increasingly becomes the character of combined pollution of ecotoxicants, including xenobiotics of radiation and chemical nature. In animal husbandry in ecologically unfavorable regions, sorbtion-detoxication technologies based on the complex application of bioprotective substances of different origin are used to reduce the intake and accumulation of xenobiotics, to normalize the physiological state of animals and to obtain safe products. It is necessary to observe certain principles ensuring compatibility of components, a wide range of bioprotective action, efficiency and safety at their use in developing the compositions of such sorption-detoxifying complexes. The article substantiates the criteria that should be followed in creating sorption-detoxifying complexes and presents groups of drugs with different mechanisms of action (sorbents, antioxidants, immunomodulators, adaptogens and other biologically active substances) for inclusion in the formulations of combined compositions.

A PROMISING ASSORTMENT OF TREES AND SHRUBS FOR LANDSCAPING IN VOLGOGRAD CITY

2021 ◽  
pp. 5-18
Author(s):  
E.N. Tyukhtina ◽  
Keyword(s):  
Negative Impact ◽  
Ornamental Plants ◽  
Botanical Garden ◽  
Climatic Conditions ◽  
Green Spaces ◽  
Ecological Situation ◽  
High Concentration ◽  
High Level ◽  
The City ◽  
Trees And Shrubs

The article deals with one of the most relevant topics of the modern city and ecology - the problem of landscaping in Volgograd. The city is characterized by an industrial urbanism, with a high concentration of population, saturation of production facilities and vehicles, which contributes to a high level of negative impact on the environment. The pace of greening of the city lags behind the pace of construction of the residential sector, and the existing green spaces do not meet the sanitary and hygienic, aesthetic requirements. The prospects of this problem are determined, the existing green spaces are considered, data on the climatic conditions of the city and the ecological situation are given. Improvement in the field of landscaping is associated with the scientifically sound placement of green spaces, taking into account all the factors that affect the growth and development of plants in the urban environment. Unfortunately, due to the uneven distribution of the assortment of trees and shrubs, the species composition of the central streets and squares of the city is extremely poor. The study focuses on the role of the botanical garden in urban landscaping and aims to create recommendations for the sorting of tree and shrub plants for urban landscaping. As a result of the analysis of the assortment of ornamental plants of the open ground of the botanical garden, the article proposed species and varieties of woody and shrubby plants that have passed the introduction tests for more than 5-10 years. Recommendations for sorting are aimed at improving the ecological situation of the city and greening the recreation areas of citizens. The proposed list of tree and shrub species cannot fully solve the problem of greening the city, but it will help to significantly enrich the composition of tree and shrub plants.

scholarly journals Survival of Lactobacillus rhamnosus GG during Simulated Gastrointestinal Conditions Depending on Food Matrix

2016 ◽  
Vol 5 (5) ◽  
pp. 56 ◽  
Author(s):  
Riin Karu ◽  
Ingrid Sumeri
Keyword(s):  
Whey Protein ◽  
Apple Juice ◽  
Negative Impact ◽  
Physiological State ◽  
Lactobacillus Rhamnosus ◽  
Maximum Growth ◽  
Food Matrix ◽  
Lactobacillus Rhamnosus Gg ◽  
Significant Drop ◽  
Gastrointestinal Conditions

When developing new probiotic foods, their protective properties in maintaining viability of probiotics under gastrointestinal conditions should be evaluated. In the current study, human upper gastrointestinal tract simulator (GITS) was used to compare the effect of different food matrixes on the survival of Lactobacillus rhamnosus GG (LGG). pH-auxostat was chosen for the cultivation of LGG cells to obtain culture samples in the same physiological state at maximum growth rate for the GITS experiments. The LGG culture was centrifuged and fast frozen in liquid nitrogen in various liquid food matrixes (commercial UHT milk, soymilk, apple juice, titrated apple juice, whey protein powder drink and M.R.S. Broth as reference) and stored at -400C. During 3-month storage, reduction of viability was significant only for apple juice. In the GITS experiments, bile had a greater negative impact on LGG than acid conditions, also the effect of food matrix was noted - in the case of milk, soymilk and whey protein powder drink only the highest concentration of bile (0.4%) caused a significant drop in the viability of bacteria when compared to apple juice. To maximize the health benefits of foodstuffs, it should be taken into account that the survival of probiotics during fast freezing, storage and gastrointestinal passage is dependent on the food matrix.

scholarly journals Invertase and sucrose synthase activities in coffee plants sprayed with sucrose solution

2003 ◽  
Vol 60 (2) ◽  
pp. 239-244 ◽  
Author(s):  
José Carlos da Silva ◽  
José Donizeti Alves ◽  
Amauri Alves de Alvarenga ◽  
Marcelo Murad Magalhães ◽  
Dárlan Einstein do Livramento ◽  
...  
Keyword(s):  
Sucrose Synthase ◽  
Sucrose Solution ◽  
Management Practice ◽  
Physiological State ◽  
Soluble Sugar ◽  
Soluble Sugars ◽  
Total Soluble Sugar ◽  
Coffee Plants ◽  
Sugar Levels ◽  
High Level

One management practice of which the efficiency has not yet been scientifically tested is spraying coffee plants with diluted sucrose solutions as a source of carbon for the plant. This paper evaluates the effect of foliar spraying with sugar on the endogenous level of carbohydrates and on the activities of invertase and sucrose synthase in coffee (Coffea arabica L.) seedlings with reduced (low) and high (normal) levels of carbon reserve. The concentrations used were 0.5 and 1.0% sucrose, and water as a control. The use of sucrose at 1.0% caused an increase in the concentration of total soluble sugars in depauperate plants, as well as increased the activity of the following enzymes: cell wall and vacuole acid invertase, neutral cytosol invertase and sucrose synthase. In plants with high level of carbon reserve, no increments in total soluble sugar levels or in enzymatic activity were observed. Regardless of treatments or plants physiological state, no differences in transpiration or stomatal conductance were observed, demonstrating the stomatal control of transpiration. Photosynthesis was stimulated with the use of 0.5 and 1.0 % sucrose only in depauperate plants. Coffee seedling spraying with sucrose is only efficient for depauperate plants, at the concentration of 1.0%.

scholarly journals Comparative genomics and pangenome-oriented studies reveal high homogeneity of the agronomically relevant enterobacterial plant pathogen Dickeya solani

2020 ◽  
Author(s):  
Agata Motyka-Pomagruk ◽  
Sabina Zoledowska ◽  
Agnieszka Emilia Misztak ◽  
Wojciech Sledz ◽  
Alessio Mengoni ◽  
...  
Keyword(s):  
Comparative Genomics ◽  
Large Scale ◽  
De Novo ◽  
Genetic Material ◽  
Soft Rot ◽  
Potato Production ◽  
Core Gene ◽  
Ecological Niches ◽  
Dickeya Solani ◽  
High Level

Abstract Background: Dickeya solani is an important plant pathogenic bacterium causing severe losses in European potato production. This species draws a lot of attention due to its remarkable virulence, great devastating potential and easier spread in contrast to other Dickeya spp. In view of a high need for extensive studies on economically important soft rot Pectobacteriaceae , we performed a comparative genomics analysis on D. solani strains to search for genetic foundations that would explain the differences in the observed virulence levels within the D. solani population. Results: High quality assemblies of 8 de novo sequenced D. solani genomes have been obtained. Whole-sequence comparison, ANIb, ANIm, Tetra and pangenome-oriented analyses performed on these genomes and the sequences of 14 additional strains revealed an exceptionally high level of homogeneity among the studied genetic material of D. solani strains. With the use of 22 genomes, the pangenome of D. solani , comprising 84.7% core, 7.2% accessory and 8.1% unique genes, has been almost completely determined, suggesting the presence of a nearly closed pangenome structure. Attribution of the genes included in the D. solani pangenome fractions to functional COG categories showed that higher percentages of accessory and unique pangenome parts in contrast to the core section are encountered in phage/mobile elements- and transcription- associated groups with the genome of RNS 05.1.2A strain having the most significant impact. Also, the first D. solani large-scale genome-wide phylogeny computed on concatenated core gene alignments is herein reported. Conclusions: The almost closed status of D. solani pangenome achieved in this work points to the fact that the unique gene pool of this species should no longer expand. Such a feature is characteristic of taxa whose representatives either occupy isolated ecological niches or lack efficient mechanisms for gene exchange and recombination, which seems rational concerning a strictly pathogenic species with clonal population structure. Finally, no obvious correlations between the geographical origin of D. solani strains and their phylogeny were found, which might reflect the specificity of the international seed potato market.

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