The Effect of Avocado to the Profile of Blood Urea Nitrogen (BUN) and Creatinine in Rats  (Rattus norvegicus) Induced with Meloxicam

Incidence of drug overdose during treatment of acute disease consequently leads to serious renal damage. As supporting treatment, administration of herbal medicine and food dietary are frequently developed. This research aimed to prove how the administration of avocado juice could lower the BUN and creatinine level in white rats induced with toxic doses of meloxicam. Meloxicam is a non-steroidal anti-inflamatory drug (NSAID), which is effectively used as an anti-inflamatory, analgesic, and antipyretic. Twenty four (24) male Wistar rats were assigned to 4 groups of six rats each (n=6). 1 ml of CMC 1% was administered to Control Group I, 30 mg/kgBB meloxicam and 1 ml of CMC 1% to Control Grup II, 30 mg/kgBB meloxicam and avocado juice 5 g/kgBB/day to Treatment Group I, and 30 mg/kgBB meloxicam and avocado juice 10 g/kgBB/day to Treatment Group II. The study was conducted over 8 days, then the level of Blood Urea Nitrogen and creatinine of the white rats were examined on the 1st and 8th day. The results were analyzed by Anova Two Way With Replication, then followed by T-test (α = 0,05) if there were difference. The Anova Two Way With Replication test showed that the mean of the four groups either the levels of Blood Urea Nitrogen or creatinine was significantly decreased (p<0,05). The decrease of BUN in the treatment group I was 27,17 27,17mg/dl and 17,83mg/dl while the decrease of creatinine level was 0,983mg/dl and 0,713mg/dl. The conclusion of this study was that avocado juice decreases level of Blood Urea Nitrogen and creatinine in white rats which exposed toxic doses of meloxicam.

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Phlebotrophic Effect of Graptophyllum Pictum (L.) Griff on Experimental Wistar Hemorrhoids

Journal of Biomedicine and Translational Research ◽

10.14710/jbtr.v5i1.3704 ◽

2019 ◽

Vol 5 (1) ◽

pp. 1

Author(s):

Mario Sadar Bernitho Hutagalung

Keyword(s):

Body Weight ◽

Treatment Group ◽

Wistar Rats ◽

Controlled Trial ◽

Anal Verge ◽

Wistar Rat ◽

Control Group ◽

Random Allocation ◽

Group I ◽

The Mean

Background : The 1st and 2nd degree hemorrhoids is managed non-operatively with the anti-inflammatory and plebothropic drugs. Graptophyllum pictum extract (GPE) has already been used widely in Indonesia to treat hemorrhoid with good result, however, the mechanism is not supported by the molecular research.Objective : This study is intended to study the phlebothropic effects of GPE by measuring the degree of edema and extravassal leucocytes of experimental wistar hemorrhoid.Methods : Experimental study with Randomized Controlled Trial Post-test only design in male wistar rats, weight around 200 gr, induced for the development of a disease-like condition of hemorrhoids by 6% croton oil on the anus for 3 days. Random allocation was performed to divide the 14 wistar rats in 2 groups. Group I as control got normal saline solution, while group II was treated with GPE 100mg/kgbw, started on day 4th for 5 consecutive days. On 9th day blood was extracted from retroorbital fossa and anus was resected up to 2 cm from anal verge and weighted. The degree of anal edema was measured by rectoanal coefficient, that is rasio between anal weight (miligrams) and body weight (grams).Results : Until the end of study, all wistar rat were still alive. The mean (±SD) of body weight of control group was 173.84 (±13.37) and the treatment group was 171.70 (±13.10), and there was no significant differences (p = 0.833). The mean (±SD) of rectoanal coefficient in the treatment group was 2.46 (±0.41) and it was significantly lower than control group (3.13 ± 0.85) (p = 0.029). The mean (±SD) of extravassal leukocytes in the treatment group was 900.14(±48.09) and it was significantly lower than the control (1003.28 ± 99.30) (p = 0.042).Conclusions : Graptophyllum pictum extract at doses of 100 mg/Kgbw have phlebotonic effect in decreased edema and extravassal leukocytes.

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THE EFFECT OF SEMBUNG LEAF EXTRACT (BLUMEA BALSAMIFERA) ON THE NUMBER AND DIAMETER OF RATS LEYDIG CELLS INDUCED BY HIGH-FAT DIET

PLANT ARCHIVES ◽

10.51470/plantarchives.2021.v21.no1.049 ◽

2021 ◽

Vol 21 (no 1) ◽

Author(s):

Gede Widhiantara ◽

Anak Agung Ayu Putri Permatasari ◽

Putu Angga Wiradana

Keyword(s):

Treatment Group ◽

Leydig Cells ◽

Wistar Rats ◽

Leaf Extract ◽

Control Group ◽

Control Group Design ◽

Core Diameter ◽

Post Test ◽

Male Wistar Rats ◽

The Mean

This study aims to determine the morphology of Leydig cells in hyperlipidemic wistar rats after having administered with sembung (Blumea balsamifera) extract orally. This study utilised a randomized post-test only control group design. The sample in this study were 16 adult male wistar rats (Rattus novergicus) aged 3-4 months with a body weight of 150-200 grams, which were equally and randomly divided into two groups, namely control group (hyperlipidaemia and sterile aquadest) and treatment group (hyperlipidaemia and sembung leaf extract). Hyperlipidaemia was induced with lard administration for 50 days. Data were analysed statistically using the Independent t-test. The results showed that the number of Leydig cells in the treatment group was higher than the control group with 68.13 ± 1.89 and 55.63 ± 1.92 cells respectively (P <0.05). In addition, the mean Leydig cell core diameter of the control group, 5.00 ± 0.34 µm, was smaller compared to the treatment group which was 5.80 ± 0.20 µm (P <0.05). It can be inferred that sembung leaf extract provides a protective effect against damage to Leydig cells due to hyperlipidaemia.

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Pengaruh Pemberian Virgin Coconut Oil Terhadap Kadar Kreatinin dan Urea Nitrogen Darah Rattus Norvegicus Jantan

Hang Tuah Medical journal ◽

10.30649/htmj.v17i2.230 ◽

2020 ◽

Vol 17 (2) ◽

pp. 181

Author(s):

NOVIANE ANGRELLA ◽

ROOSTANTIA INDRAWATI ◽

LESTARI DEWI

Keyword(s):

Creatinine Level ◽

Blood Urea Nitrogen ◽

Coconut Oil ◽

The Body ◽

Virgin Coconut Oil ◽

Urea Nitrogen ◽

Waste Products ◽

Nitrogen Levels ◽

Functional Product ◽

Male Wistar Rats

ABSTRACTBackground: Virgin Coconut Oil (VCO) is a functional product that is highly favored and have been widely applied in the everyday lives of society. The increase of the frequencies and duration of VCO consumption is suspected that VCO could negatively impact the target organ. The kidney is a vital organ in the human body, it is responsible for clearing out the residual waste products of metabolism in the body. The evalution of the kidney’s function can be done through the measurement of creatinine and blood urea nitrogen. The purpose of this study is to determine the effect of VCO administration on kidney function.Method: 24 male wistar rats that are divided into 4 groups, which are listed as follows, K(-) or a negative-controlled group, P(1) or the first group of rats that are given VCO with a dose of 2mL/200gr of the rats’ total BW/day, P(2) or the second group of rats that are given VCO with a dose of 3mL/200gr of the rats’ total BW/day, and P(3) or the third group of rats that are given VCO with a dose of 4mL/200gr of the rats’ total BW/day for 28 dayResults: Administrating VCO with a dose of 2mL/200gr and 3mL/200gr of the rats’ total BW/day does not affect the blood’s creatinine level while with a dose of 4mL/200gr of the rats’ total BW/day decreases the blood’s creatinine level. Administrating VCO with a dose of 2 mL/200gr, 3 mL/200gr, and 4 mL/200gr of the rats’ total BW/day does not affect the level of blood urea nitrogen.Conclusion: Administration of VCO dose of 4 mL / 200 g BW rat / day significantly decreased blood creatinine levels in experimental animals, while other doses did not affect the creatinine levels or blood urea nitrogen levelsKeywords: Virgin Coconout Oil (VCO), cretinine, blood urea nitrogen.

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Pemberian Ekstrak Daun Gandarusa (Justicia gendarussa Burm. f.) Menurunkan Kadar F2-isoprostan Urin Tikus Wistar (Rattus norvegicus) Jantan yang Diinduksi Latihan Fisik Berlebih

JURNAL BIOMEDIK (JBM) ◽

10.35790/jbm.9.3.2017.17337 ◽

2017 ◽

Vol 9 (3) ◽

Author(s):

DG Ika Akpriyanti ◽

Wimpie Pangkahila ◽

IGM Aman

Keyword(s):

Treatment Group ◽

Physical Training ◽

Rattus Norvegicus ◽

Wistar Rats ◽

Leaf Extract ◽

Control Group ◽

Oxygen Species ◽

Post Test ◽

Male Wistar Rats ◽

The Mean

Abstract: Excessive physical activity increases the consumption of oxygen which can result in increased levels of reactive oxygen species (ROS) causing oxidative stress characterized by the elevation of F2-isoprostane as a byproduct of lipid peroxidation. Willow (Justicia gendarussa Burm. f.) has an antioxidant activity that is able to inhibit and break the chain reaction of free radicals and prevent lipid peroxidation. This study was aimed to prove that willow leaf extract could inhibit the elevation of F2-isoprostane levels in male Wistar rats (Rattus norvegicus) urin induced by excessive physical training. This was a true experimental study using 16 male Wistar rats (Rattus norvegicus), aged 2-3 months, weighing 180-200 g as subjects. The control group (P0) was treated with a placebo and excessive physical training, and the treatment group (P1) was treated with the willow leaf extract of 200mg/rat/day and excessive physical training. Before and after 14 days of treatment, the urine samples were collected and their levels of F2-isoprostane 8-isoPGF2α were examined by using enzyme immunoassay kit (EIA). The results showed that the mean level of F2-isoprostane in the control group (P0) before treatment (pretest) was 5.20±0.483 ng / mL while in the treatment group (P1) was 5.46±0.655 ng / mL (P > 0.05). On the other hand, after treatment for 7 days (post-test), the mean level of F2-isoprostane in the control group (P0) was 5.34±0.476 ng/mL and in the treatment group (P1) was 3.61±0.389 ng/mL (P < 0.01). Conclusion: The extract of willow (Justicia gendarussa Burm. f.) leaf could inhibit the elevation of F2-isoprostane levels in male Wistar rats (Rattus norvegicus) urin induced by excessive physical training.Keywords: willow leaf, F2-isoprostane, excessive physical trainingAbstrak: Aktivitas fisik berlebih akan meningkatkan komsumsi oksigen yang dapat mengakibatkan peningkatan kadar reactive oxygen species (ROS) sehingga menyebabkan stres oksidatif yang ditandai dengan meningkatnya F2-isoprostan sebagai salah satu produk peroksidasi lipid. Tanaman gandarusa (Justicia gendarussa Burm. f.) mengandung antioksidan yang dapat mencegah reaksi peroksidasi lipid. Penelitian ini bertujuan untuk membuktikan bahwa pemberian ekstrak daun gandarusa dapat menurunkan kadar F2-isoprostan urin tikus Wistar (Rattus norvegicus) jantan yang diinduksi latihan fisik berlebih. Jenis penelitian ialah eksperimental dengan subjek 16 ekor tikus (Rattus norvegicus), galur Wistar, sehat, berumur 6 bulan, berat badan 180-200 gr, dengan kadar F2-isoprostan >2ng/mL. Kelompok kontrol (P0) diberikan pelatihan fisik berlebih dan plasebo aquadest 2ml sedangkan kelompok perlakuan (P1) diberikan pelatihan fisik berlebih dan ekstrak daun gandarusa dosis 200mg/ekor/hari. Sebelum dan setelah 14 hari perlakuan, sampel urin ditampung dan diperiksa kadar F2-isoprostan menggunakan 8-isoPGF2α enzyme immunoassay kit (EIA) dari assay design untuk data pretest dan post-test. Hasil penelitian menunjukkan rerata kadar F2-isoprostan pada kelompok P0 sebelum perlakuan (pretest) ialah 5,20±0,483 ng/mL, sedangkan pada kelompokP1 ialah 5,46±0,655 ng/mL (P > 0,05). Setelah perlakuan selama 14 hari (post-test), rerata kadar F2-isoprostan pada kelompok P0 ialah 5,34±0,476 ng/mL dan pada kelompok P1 ialah 3,61±0,389 ng/mL (P < 0,01). Simpulan: Ekstrak daun gandarusa (Justicia gendarussa burm. f.) dapat menurunkan kadar F2-isoprostan urin tikus Wistar (Rattus norvegicus) jantan yang diinduksi latihan fisik berlebih.Kata kunci: daun gandarusa, F2-isoprostan, pelatihan fisik berlebih

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Renal-protective Activity of Dried Gel of Aloe barbadensis (Elwa) on Gentamicin- Induced Nephrotoxicity in Albino Rats

Current Traditional Medicine ◽

10.2174/2215083806999201020211934 ◽

2020 ◽

Vol 06 ◽

Author(s):

Aslam M. ◽

Shabana Rahman ◽

Kalim Javed ◽

Fahamiya Nazeem ◽

Shiffa Mohamed

Keyword(s):

Blood Urea Nitrogen ◽

Renal Damage ◽

Skin Diseases ◽

Kidney Diseases ◽

Control Group ◽

Albino Rats ◽

Histopathological Analysis ◽

Aloe Barbadensis ◽

Urea Nitrogen ◽

Group I

Introduction:: Elwa (Aloe barbadensis / Aloe vera) also known as Sibr in Unani medicine which is dried juice obtained by the inspissations and used to treat many diseases, especially digestive disorders, arthritis, gastric ulcer, jaundice, amenorrhoea, kidney diseases, diseases of spleen and liver, constipation, nervine disorders, wounds, burns, scalds and other skin diseases. Methods:: The aim of this study was to evaluate the nephroprotective activity of Aloe barbadensis gel (ABG) on gentamicin-induced nephrotoxicity in rats. Wistar rats were divided into four groups of six animals in each. Group I (control); group II, III and IV were administered gentamicin 100 mg/kg/d subcutaneously from day four to eight. The lower (350 mg/kg) and higher doses (1260 mg/kg) of crude ABG were co-administrated orally in group III and group IV from day 1. On 9th day animals were sacrificed and serum was studied for blood urea nitrogen and serum creatinine and kidneys were prepared for histo-pathological analysis. Gentamicin alone treated group showed increased levels of blood urea nitrogen (118.76  0.90) and creatinine (3.42  0.13) were significantly inhibited in groups pretreated with lower [blood urea nitrogen (40.130.56); creatinine (1.640.13)] and higher [blood urea nitrogen (55.79  0.71); creatinine (2.50  0.06)] doses of crude Aloe barbadensis gel. Results:: The histopathological analysis also showed the protective nature of Aloe barbadensis gel in gentamicin-induced renal damage. Discussion:: In conclusion, the biochemical parameters and histopathological results confirmed nephroprotective effect of the crude Aloe barbadensis gel against gentamicin induced renal damage.

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Morel berry leaf extract reduce levels of reactive oxygen species and increase levels of endothelial nitric oxide synthase of male Wistar rat exposed to cigarette smoke

Neurologico Spinale Medico Chirurgico ◽

10.36444/nsmc.v4i1.148 ◽

2021 ◽

Vol 4 (1) ◽

pp. 28-31

Author(s):

Felicia Hartono ◽

Gde Ngurah Indraguna Pinatih ◽

Anak Agung Ayu Ngurah Susraini

Keyword(s):

Treatment Group ◽

Cigarette Smoke ◽

Endothelial Nitric Oxide Synthase ◽

Leaf Extract ◽

Control Group ◽

Oxygen Species ◽

Male Wistar Rats ◽

The Mean ◽

Oxide Synthase ◽

Endothelial Nitric Oxide

Background: Exposure to cigarette smoke increased the level of reactive oxygen species (ROS) and caused oxidative stress which could lead to early aging includes vascular aging. Morel berry leaf contained flavonoid works as antioxidant that neutralized ROS. This study aimed to investigate effectivenes of Morel berry (Physalis angulata L.) leaf extract to decrease levels of ROS and increase levels of endothelial nitric oxide synthase (eNOS) in male Wistar rats exposed to cigarette smoke. Method: This research was an experimental study with pre test-post test control group design. 16 healthy male rats (Rattus norvegicus), Wistar strain, 3-4 months, weight 180-200gr were used, divided randomly into two groups. The control group was given aquadest and the treatment group was given Morel berry leaf extract 500 mg/kgBW/day. Continued to 30 minutes exposed to cigarette smoke. ROS and eNOS levels were measured before and after 28 days treatment, using rat ROS ELISA Kit and rat ENOS ELISA Kit respectively. Results: The results showed that the mean ROS levels in the treatment group decreased significantly and was significantly lower than in control group (75.789 + 3.298 vs 91.646 + 1.970; p < 0.001). The mean eNOS levels in the treatment group increased significantly and was significantly higher than control group (8.597 + 0.375 vs 5.957 + 0.329; p < 0.001). Conclusion: The results of this study indicated that administration of Morel berry leaf extract reduced levels of ROS and increased serum levels of eNOS in male Wistar rats exposed to cigarette smoke.

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Assessment of Acute Kidney Injury in Patients Undergoing Elective Coronary Angiography and Percutaneous Coronary Intervention

Cardiovascular Journal ◽

10.3329/cardio.v5i1.12227 ◽

2012 ◽

Vol 5 (1) ◽

pp. 37-43

Author(s):

ABMM Alam ◽

M Moniruzzaman ◽

MB Alam ◽

N Islam ◽

F Khatoon ◽

...

Keyword(s):

Serum Creatinine ◽

Contrast Media ◽

Creatinine Level ◽

Ace Inhibitor ◽

Kidney Injury ◽

Coronary Intervention ◽

Group I ◽

Percutaneous Coronary ◽

The Mean ◽

Group Ii

Background: CIN has gained increased attention in the clinical setting, particularly during cardiac intervention but also in many other radiological procedures in which iodinated contrast media are used. There is at present good clinical evidence from well-controlled randomized studies that CIN is a common cause of acute renal dysfunction.Methodology: This was a prospective study conducted among the patients who underwent coronary angiography and percutaneous coronary intervention in the Department of Cardiology, Dhaka Medical College Hospital during January 2010 to December 2010. A total of 111 patients age range from 25 to 75 years were included in the study. Serum creatinine level at baseline and at the end of 48 hours was done in all these patients. Study population was divided into two groups according to development of acute kidney injury (AKI). Group-I = AKI, Group II = Not developed AKI. Results: AKI developed 11.7% of the study patient. DM and Preexisting renal insufficiency were significantly higher in group I patients. HTN was (61.5% Vs 44.9%) higher in group I but not significantly. History of ACE inhibitor/ARB, NSAID intake and LVEF <40% were significantly higher in group I patients. The mean±SD volume of CM (Contrast Media) were 156.9±44.8 ml and 115.4±30.0 ml in group I and group II respectively, which was significant. The mean±SD of serum creatinine after 48-72 hours of CAG/PCI was 1.4±0.37 mg/dl and 1.1±0.2 mg/dl in group I and group II respectively. The serum creatinine level increased significantly (p<0.05) after 48-72 hours of CAG/PCI in group I. In group II, S. creatinine level increased but not significant (p>0.05). Impaired renal function was found 76.9% and 2.0% in group I and group II respectively. DM, HTN, preexisting renal insufficiency, ACE inhibitor/ARB, NSAIDs, contrast volume (>150 ml), eGFR (<60 ml/min/ 1.73m2) and LVEF (<40%) are significantly (p0.05) associated for CIN development.Conclusion: CIN is an iatrogenic but preventable disorder results from the administration of contract media. Although rare in the general population, CIN occurs frequently in patients with underlying renal dysfunction and diabetes. In patients with pre angiographic normal renal function, the prevalence is low but in pre-existing renal impairment it may pose a serious threat. Thus risk factors are synergistic in their ability to predispose to the development of CIN. A careful risk-benefit analysis must always be performed prior to the administration of contrast media to patients at risk for CIN. DOI: http://dx.doi.org/10.3329/cardio.v5i1.12227 Cardiovasc. j. 2012; 5(1): 37-43

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Effect of High Plane of Nutrition on Blood Biochemical Profile and Onset of Puberty in Prepubertal HF X Kankrej Crossbred Heifers

THE INDIAN JOURNAL OF VETERINARY SCIENCES AND BIOTECHNOLOGY ◽

10.21887/ijvsbt.15.2.4 ◽

2019 ◽

Vol 15 (02) ◽

pp. 14-17

Author(s):

K K Hadiya ◽

A J Dhami ◽

D V Chaudhari ◽

P M Lunagariya

Keyword(s):

Body Weight ◽

Treatment Group ◽

Plasma Levels ◽

Age Of Onset ◽

The Body ◽

Monthly Interval ◽

Control Group ◽

Blood Biochemical ◽

Lower Protein ◽

The Mean

This study was initiated on 24 prepubertal Holstein x Kankrej crossbred heifers of nearly identical age (7-9 months) and body weight (130-140 kg) at University farm to evaluate the effect of high plane of nutrition on blood biochemical and minerals profile and the age at puberty. Twelve heifers were managed under routine farm feeding (control) and the rest 12 under ideal optimum feeding regime (treatment) that included extra 1 kg concentrate, 30 g min mix and ad-lib dry fodder. The body weight and ovarian ultrasonography together with blood sampling was carried out at monthly interval from 10 to 18 months of age to study the ovarian dynamics and blood biochemical changes. High plane of nutrition to growing heifers was beneficial in reducing the age of onset of puberty (by 2-3 months) compared to routine farm fed group. The mean plasma total protein and cholesterol concentrations showed a rising trend with significant variations from 10 to 16 months of age, where it got mostly stabilized indicating adult profile. The activity of enzymes GOT and GPT also rose gradually and significantly from 10 months till 14-15 months of age, and thereafter it remained more or less static till 18 months of age. The levels of both these enzymes were higher, with lower protein and cholesterol, in control than the treatment group from 15-16 months of age onwards. The mean plasma levels of both calcium and phosphorus increased gradually and significantly with advancing age till 16-17 months of age, with little higher values in supplemented than a control group. The plasma levels of zinc, iron, copper, and cobalt also showed rising trend with significant differences between 10th and 12th-14th months of age, and from 15th to 18th months of age the levels were statistically the same in all the groups with slightly higher values in the treatment group.

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Anticarcinogenic effect of probiotic fermented milk and chlorophyllin on aflatoxin-B1-induced liver carcinogenesis in rats

British Journal Of Nutrition ◽

10.1017/s0007114511003953 ◽

2011 ◽

Vol 107 (7) ◽

pp. 1006-1016 ◽

Cited By ~ 46

Author(s):

M. Kumar ◽

V. Verma ◽

R. Nagpal ◽

A. Kumar ◽

P. V. Behare ◽

...

Keyword(s):

Wistar Rats ◽

Lactobacillus Rhamnosus ◽

Thiobarbituric Acid ◽

Fermented Milk ◽

Hepatoprotective Effect ◽

Control Group ◽

Time Interval ◽

Group I ◽

Male Wistar Rats ◽

Aflatoxin B

The present investigation was carried out to evaluate the hepatoprotective effect of probiotic fermented milk (FM) containing Lactobacillus rhamnosus GG and Lactobacillus casei strain Shirota, alone as well as in combination with chlorophyllin (CHL) as an antioxidant agent in male Wistar rats administered aflatoxin-B1 (AFB1). AFB1 was injected intraperitoneally at the rate of 450 μg/kg body weight per animal twice a week for 6 weeks, maintaining an equal time interval between the two consecutive AFB1 administrations. A total of 125 male Wistar rats were randomly allocated to five groups, each group having twenty-five animals. Group I was offered FM containing L. rhamnosus GG and L. casei strain Shirota. Group II was administered AFB1 and served as the control group; group III was administered FM-AFB1, in which besides administering AFB1, FM was also offered. Group IV was offered CHL and AFB1, and group V was offered both FM and CHL along with AFB1. The rats were euthanised at the 15th and 25th week of the experiment and examined for the biochemical and hepatopathological profile. A significant reduction in thiobarbituric acid-reactive substances (TBARS) was observed in the FM–CHL–AFB1 group compared with the AFB1 control group. FM alone or in combination with CHL was found to show a significant (P < 0·05) hepatoprotective effect by lowering the levels of TBARS and by enhancing the activities of antioxidant enzymes such as glutathione peroxidase, superoxide dismutase, catalase and glutathione-S-transferase, indicating that probiotic FM alone or in combination with CHL possesses a potent protective effect against AFB1-induced hepatic damage.

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Collaborative model as a training for increasing village health worker competency about complementary feeding

JURNAL GIZI INDONESIA ◽

10.14710/jgi.9.2.198-207 ◽

2021 ◽

Vol 9 (2) ◽

pp. 198-207

Author(s):

Habibah Abidin ◽

Apoina Kartini ◽

Ani Margawati

Keyword(s):

Treatment Group ◽

Health Worker ◽

Self Efficacy ◽

Complementary Feeding ◽

Control Group ◽

Counseling Skills ◽

Collaborative Model ◽

Village Health Worker ◽

The Mean ◽

Village Health

Background: A Kader refers to a Village Health Worker (VHW), a volunteer, which becomes one of the sources of community reference. Commonly, they sustain a mother's knowledge regarding adequate complementary feeding. However, there are still some VHW who have not possessed a health education background nor been able to be independent.Objectives: This study aimed to analyze the impact of collaborative models on VHW's competence as in knowledge, self-efficacy, attitudes, and counseling skill on the topic of complementary feeding.Materials and Methods: The design of this research is a quasi-experiment control group pretest-postest, with the retrieval of subjects using purposive sampling. Subjects were selected based on the location of the posyandu. The population in this research was VHWs in the Lembang district were 40 VHWs in each group. The treatment group was given training intervention for 1 month with a collaborative model, combining several methods into a series. The main topic was counseling and complementary feeding. The control group was given booklets and leaflets. VHW's competence was measured using questionnaires. This research was conducted in January-April 2020.Results: Statistical test results before the treatment of both groups showed no difference (p>0,05) in each variable. Two months after the intervention, there were significant differensces in the mean score of knowledge (p=0,001), attitude (p=0,001), and VHWs self-efficacy (p=0,000) in both groups. VHW counseling skills (p=0,149) until the first month there was not a significant difference. Unexpectedly, in the second month, the VHW counseling skills could not be observed due to the global COVID-19 pandemic. The mean score of each group increased significantly, but the score of the treatment group was higher than the control group.Conclusions: A collaborative model is effective when compared to only providing booklets and leaflets in increasing VHW's knowledge, attitudes, and self-efficacy but not effective yet for VHW counseling skills.

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