scholarly journals Effect of L-citrulline, L-leucine, and multicomponent exercises on body compositions, physical activity, and amino acid concentrations in older Japanese women with low body mass index: A randomized double-blind placebo-controlled study

Author(s):  
Mijin Kim ◽  
Hiroko Isoda ◽  
Tomohiro Okura

Abstract Background: The intake of citrulline (CIT) and leucine (LEU) can stimulate protein synthesis. However, the efficacy of the combined intervention of CIT and LEU intake with exercise on body composition and physical activity (PA) remains unclear. This study aimed to investigate the combined effect of CIT and LEU intake and weight-bearing exercises (WBE) and square stepping exercise (SSE) for 20 weeks on body composition, PA, and amino acid concentration in older women with low body mass index (BMI) (16 to 21 kg/m 2 ). Methods: A total of 23 participants practiced WBE and SSE once a week for 75 minutes and were administered supplement (Ex + CIT·LEU group: CIT 0.8 g and LEU 1.6 g; Ex + Placebo group: 3.5 g carbohydrate) twice a day for 20 weeks. Body composition was measured using dual-energy X-ray absorptiometry. PA, including leisure-time, household, and occupational PA, was assessed using the Physical Activity Scale for the Elderly. Amino acid concentrations in the blood were analyzed by high-performance liquid chromatography.Results: Significant interactions were observed in the body weight, BMI, lean mass, body mass, household and total PA, tyrosine, and phenylalanine. The within-group analysis showed that tyrosine of post-intervention measurement (Post) significantly in both groups ( p < 0.05). Body weight, BMI, lean mass, body mass, household PA, total PA, and phenylalanine of Post increased significantly in the Ex + CIT·LEU group ( p < 0.05). Additionally, significant positive correlations were observed between the intake rate of supplements and bone mass ( r = 0.80) and between the practice rate of WBE at home and bone mineral density ( r = 0.66) in the Ex + CIT·LEU group. Conclusion: Our findings suggest that the intake of CIT and LEU, with the practice of WBE and SSE, could improve body weight, muscle mass, bone mass, and PA in older women with low BMI, which may prevent sarcopenia and frailty.Trial registration: UMIN000022385. Registered 20 May 2016, https://upload.umin.ac.jp/cgi-open-39 bin/ctr/ctr.cgi?function=brows&action=brows&recptno=R000025797&type=summary&language=J

Foods ◽  
2021 ◽  
Vol 10 (12) ◽  
pp. 3117
Author(s):  
Mijin Kim ◽  
Hiroko Isoda ◽  
Tomohiro Okura

The combined intake of citrulline (CIT) and leucine (LEU) can stimulate protein synthesis. Therefore, this study aimed to investigate the effect of combined intake of CIT and LEU accompanied by exercise for 20 weeks on body composition, physical activity (PA), and amino acid concentrations in older Japanese women with low body mass index (BMI) (16 to 21 kg/m2) using a randomized, double-blind, placebo-controlled design. The supplement was administered twice a day for 20 weeks (Ex (exercise) + CIT·LEU group, n = 10: mainly 0.8 g CIT and 1.6 g LEU; Ex + Placebo group, n = 13: mainly 3.5 g carbohydrate). Additionally, both groups exercised (weight-bearing exercise, square stepping exercise) once a week for 75 min. Body composition, PA, and amino acid concentrations in the plasma were measured. Body weight, BMI, body mass, household PA, total PA, and phenylalanine significantly increased in the Ex + CIT·LEU group (p < 0.05) post intervention. This study suggests that the combined intake of CIT and LEU accompanied by exercise can improve body weight, BMI, body mass, and PA in older women with low BMI, which may prevent sarcopenia and frailty.


2021 ◽  
Vol 13 (16) ◽  
pp. 8775
Author(s):  
Laura Redondo-Flórez ◽  
Domingo Jesus Ramos-Campo ◽  
Vicente Javier Clemente-Suárez

The aim of the present study was to analyse body composition, anxiety, cardiovascular, and physical activity factors related with academic performance of school students as well as to analyse differences, by age, in these factors. We analysed in 266 primary school students’ (8.81 ± 1.62 years, range: 5–13 years) heart rate, anthropometric variables to calculate body mass index, physical activity performance, anxiety levels and academic results by the average of marks. Students were divided in two different groups, firstly by their lower or higher academic performance, and secondly by age. Results showed a negative correlation between academic performance and age, weight, body mass index and trait anxiety variables. Additionally, significant differences were found by age, presenting older students higher scores in body mass index and lower physical activity, trait anxiety, heart rate and academic performance values than younger students. Overweight and obesity may have a great impact in academic performance in children and we pointed out the necessity to establish programs related with healthy habits which include improvements in physical activity and nutrition behaviours with the objective to enhance children’s health general status, psychological profile, cognitive and motor development, and academic performance.


2003 ◽  
Vol 88 (12) ◽  
pp. 5914-5920 ◽  
Author(s):  
Yumi Matsushita ◽  
Tetsuji Yokoyama ◽  
Nobuo Yoshiike ◽  
Yasuhiro Matsumura ◽  
Chigusa Date ◽  
...  

Abstract The β3-adrenergic receptor (ADRB3) is expressed mainly in visceral adipose tissue and is thought to contribute to lipolysis and the delivery of free fatty acids to the portal vein. Although many studies have examined the relationship between the Trp64Arg mutation of ADRB3 and obesity, the results have been inconsistent. We examined the cross-sectional relationship of ADRB3 variants with indexes of obesity, and their longitudinal changes over 10 yr, in men and women, aged 40–69 yr, who were randomly selected from the Japanese rural population. The study considered both dietary energy intake and physical activity levels. Among the 746 participants, the genotype frequencies of the Trp64Trp, Trp64Arg, and Arg64Arg variants were 483, 224, and 39, respectively. The cross-sectional analysis showed no significant differences in height, weight, body mass index, blood pressure, serum total and high density lipoprotein cholesterols, and hemoglobin A1c among the genotype groups even after adjustments for gender, age, smoking, alcohol drinking, physical activity, and energy intake. No significant differences in the weight changes between the genotype groups were evident in the longitudinal analysis. We conclude that the Trp64Arg mutation of ADRB3 has little or no influence on either body weight or body mass index in the general Japanese population.


2017 ◽  
Vol 27 (1) ◽  
pp. 56 ◽  
Author(s):  
Willian R. Tebar ◽  
Luiz Carlos M. Vanderlei ◽  
Catarina C. Scarabotollo ◽  
Edner F. Zanuto ◽  
Bruna T. C. Saraiva ◽  
...  

Objectives: The aim of this study was to determine the prevalence of abdominal obesity and its associated factors among adolescents, independent of confounders. Method: A sample of 14–17-year-old individuals (n=1.231), who were students from Londrina/PR-Brazil public schools, was studied. A questionnaire about physical activity, sedentary behaviour and socioeconomic conditions was applied. Anthropometry was composed of body weight (kg), height (m), body mass index (BMI=kg/m²) and waist circumference (cm). The association of abdominal obesity and independent variables was assessed using the chi-square test and the magnitude of associations was verified using Binary Logistic Regression in an unadjusted model and adjusted for confounders (gender, age, socioeconomic status, physical activity and sedentary behaviour). The confidence interval and statistical significance were set at 95% and 5%, respectively, using SPSS v15.0. Results: The abdominal obesity prevalence was 17.5% (CI = 15.4%–19.6%), and was higher in boys than in girls. Adolescents with abdominal obesity had higher values of body weight, height, body mass index and sedentary behaviour compared to eutrophic individuals. Being male increased the risk of abdominal obesity by 36% in adolescents. This risk was two times higher in those with high levels of sedentary behaviour. Conclusion: Abdominal obesity was significantly associated with gender and high levels of sedentary behaviour, regardless of confounding factors. Lifestyle habits are important modifiable risk factors that can effectively contribute to the reduction of obesity from an early age.


Author(s):  
Futoon S. Alobiri ◽  
Roaa A. Alharbi ◽  
Mohammed R. Algethami ◽  
Raghdah H. Ateeq ◽  
Aseel M. Badurayq ◽  
...  

Aim: Identify the relation between poor esteem for body image and weight-related behaviors. The results will help increase awareness and improve students’ lifestyles to have a better body image and achieve ideal body weight. Methods: A cross-sectional study was conducted among King Abdulaziz University medical students (n= 460) between July to the end of August 2019. Data was collected using the International physical activity questionnaire (IPAQ), figure rating scale (FRS) and analyzed using SPSS software. Result: The results showed that the average Body Mass Index (BMI) was 24.80 ± 11.89. Participant sex was an important factor influencing the prevalence of obesity; male students were more obese than female students with a significant difference (p<0.001). The level of body satisfaction was also affected by gender. Students in preclinical years were more likely to gain weight more than clinical years students. Conclusion: The results show a significant relationship between body satisfaction and gender (P<0.0001) despite having diverse BMIs. Overweight and obese males and females' participants had the lowest body satisfaction. Females who were too thin and had low BMIs described themselves as normal, while males describe themselves as too thin. Conversely, females with high BMIs described themselves as too fat, while males described themselves as normal. This could be due to different factors. Also, underweight females and males have high body satisfaction, which can lead to dangerous behaviors to maintain low body weight which cause negative health consequences.


Circulation ◽  
2014 ◽  
Vol 130 (suppl_2) ◽  
Author(s):  
Patricia E Longmuir ◽  
Mary Corey ◽  
Guy Faulkner ◽  
Jennifer L Russell ◽  
Brian W McCrindle

Introduction: This cross-sectional study evaluated the healthy, active lifestyle capacity (daily physical activity, strength, flexibility, body composition) of children after Fontan, which was hypothesized to be lower than healthy peers. Methods: Participants (n=64, 25 female) were 9 ± 2 years of age. Fontan completion occurred at 3 ± 1 years of age. Canadian Health Measures Survey protocols assessed aerobic endurance (walking up/down steps at set pace), strength (handgrip dynamometry), flexibility (sit and reach), body composition (body mass index) and daily moderate-to-vigorous physical activity (7-day accelerometry). Participant versus published norm differences were evaluated with t-tests. Linear regression evaluated associations with age/gender/demographic factors. Results: Children after Fontan had strength scores similar (mean difference 1 kg) to their peers, were less likely to be obese (mean difference of body mass index = 1.1 ± 2.5, p=.001) and performed 50 minutes of moderate-to-vigorous activity per day. Estimated maximal aerobic endurance (mean difference = 21 ± 3 ml/kg/min or 61% of expected) and flexibility (mean difference = 9 ± 8 cm or 64% of expected) were lower than peers(p<.001). Participants performed fewer minutes of daily activity (mean difference from normal 12 ± 17 minutes/day, p<.001), but almost all (60/63) demonstrated the capacity for at least 20 minutes per day. Daily activity was higher with Fontan completion at a younger age (4 ± 2 mins/year) and for those taking antithrombotic medication (7 ± 18 and 22 ± 17 fewer minutes/day for those taking/not taking antithrombotics, respectively). Conclusions: Children after Fontan demonstrate the capacity to successfully perform the daily physical activity associated with optimal health. They have similar levels of strength and good body composition. We recommend that children after Fontan be counselled to expect that they can successfully participate in physically active peer play.


2010 ◽  
Vol 68 (2) ◽  
pp. 277-281 ◽  
Author(s):  
Camilla N. De Gaspari ◽  
Carlos A.M. Guerreiro

Antiepileptic drugs (AED) may cause body weight changes. OBJECTIVE: To evaluate the dietary habits and body weight associated with AED in epileptic patients. METHOD: Sixty-six patients were subjected to two interviews, and had their weight and body mass index calculated and compared at both times, interval between six to eight months. RESULTS: It was observed that 59.1% showed weight gain. The patients who had no weight gain had a greater proportion of individuals who engaged in some form of physical activity. However, of the 45 patients who maintained their initial dietary and medication pattern, 75.6% recorded a weight gain. Weight gain was seen in 66.7% of patients on carbamazepine (n=18), 60% on valproate (n=5), 50% on carbamazepine+clobazam treatment (n=14), and 58.3% of patients on other(s) polytherapy (n=12). CONCLUSION: The patient should be alerted to possible weight gain, and should be advised about dieting and participating in regular physical activity.


2012 ◽  
Vol 05 (03) ◽  
pp. 134-138 ◽  
Author(s):  
Roberta Deh Souza Santos ◽  
Eduarda de Castro Furtado ◽  
Flávia Giolo Deh Carvalho ◽  
Renata Iannetta ◽  
Carla Barbosa Nonino ◽  
...  

ABSTRACT Background: Polytherapy treatment is a common practice observed among menopausal patients. This study aimed to quantify food intake and medications in climacteric patients living in community. Methods: Eligible patients from Climacteric Outpatient Clinic (HCFMRP/USP) were recruited. The collected data were: food intake records, age, body weight, height, levels of physical activity and medications in use. Results: Eighty women were studied. Their age was 548 years and body mass index 307kg/m2. They had inadequate dietary Fe, K, Mg, Ca, thiamin, pyridoxine, vitamin E, folate and fiber consumption; 62% used 3 or more medications/day among hypotensive, micronutrients and anti-depressants. Conclusion: Climacteric women need special attention regarding nutrient intake and medication prescription.


2018 ◽  
Vol 2018 ◽  
pp. 1-9 ◽  
Author(s):  
Ana Paula dos Santos Rodrigues ◽  
Lorena Pereira Souza Rosa ◽  
Hugo Delleon da Silva ◽  
Elisângela de Paula Silveira-Lacerda ◽  
Erika Aparecida Silveira

Background. ThePPARG2Pro12Ala (rs1801282) andIL6-174G >C (rs1800795) have important function in body weight regulation and a potential role in obesity risk. We aimed to investigate the association betweenPPARG2Pro12Ala andIL6-174G >C variants and the genotypes interaction with body composition, metabolic markers, food consumption, and physical activity in severely obese patients.Methods. 150 severely obese patients (body mass index (BMI) ≥ 35 kg/m2) from Central Brazil were recruited. Body composition, metabolic parameters, physical activity, and dietary intake were measured. The genotype was determined by the qPCR TaqMan Assays System. Multiple linear regression and multiple logistic regression models were fitted adjusting for confounders.Results. Ala carriers of the Pro12Ala polymorphism had higher adiposity measures (BMI:p=0.031, and fat mass:p=0.049) and systolic blood pressure (p=0.026) compared to Pro homozygotes. We found no important associations between the -174G >C polymorphism and obesity phenotypes. When genotypes were combined, individuals with genotypes ProAla + AlaAla and GC + CC presented higher BMI (p=0.029) and higher polyunsaturated fatty acids (PUFAs) consumption (p=0.045) compared to the ones with genotypes ProPro and GG, and individuals carriers of thePPARG2Ala allele only (genotype ProAla + AlaAla and GG) had higher fat mass and systolic and diastolic blood pressure compared to the ones with genotypes ProPro and GG.Conclusions. Severely obese individuals carrying the Ala allele of thePPARG2Pro12Ala polymorphism had higher measures of adiposity and blood pressure, while no important associations were found for theIL6-174G >C polymorphism.


Sign in / Sign up

Export Citation Format

Share Document