Overview of the Russian market of herbal products

2021 ◽  
pp. 11-22
Author(s):  
Natalia V. Safonova ◽  
Elena O. Trofimova
Keyword(s):  
Dietary Supplements ◽  
Raw Materials ◽  
Dosage Forms ◽  
Annual Growth Rate ◽  
Sources Of Information ◽  
Herbal Products ◽  
Preparation Methods ◽  
Plant Raw Materials ◽  
Foreign Products ◽  
Scope Of Application

Introduction. In the Russian pharmaceutical market, there is the following situation: herbal medicinal products (HMP) and dietary supplements based on plant raw materials (DS) have similar compositions, dosage forms and scope of application. They’re often considered analogues by consumers and specialists, which indicates the existence of common market for these products.Research aim is to investigate the state and development trends of the Russian HMP and DS market, assessing positions of foreign and domestic companies and general prospects for this market as well.Methodology. The study was conducted using IQVIA retail audit database, official sources of information on HMP and DS registration. In the market analysis the products were classified depending on the scope of application, composition and preparation methods, and dosage forms as well.Results. In 2020 pharmacy of HMP and DS sales amounted to 435.4 million units valued at 51.3 billion rubles in wholesale prices. Beginning with 2016, the average annual growth rate corresponded to 4.2%, in value terms. However, in volume terms, the sales were reduced in the average by 3.4% per year (due to cheap domestic medicines). The main part of the entire market comprises HMP (80% in units and 74% in value terms in 2020). The products, affecting respiratory system, genitourinary sphere, and digestion, provide more than three-quarters of all sales in value terms. More than half of the market is occupied by total extractive drugs. Solid dosage forms (tablets and capsules) account for half of the sales, plant raw materials and fees constitute more than one third. In 2020, Russian companies provided 28% of the sales of HMP and 67% of DS in value terms. In the context of the main segments, the market structure in 2016-2020 remained fairly stable.Conclusion. In the future, the market dynamics in value terms will be determined considering by household income and the epidemiological situation. In units, HMP sales will continue to decline through the unprofitable positions of the traditional domestic drug assortment. The increasing strictness of legislation requirements for the market of dietary supplements may contribute to investment in the development of HMP that are competitive to foreign products in terms of quality and consumer characteristics.

CHOOSING THE OPTIMAL TECHNOLOGY FOR OBTAINING DRY STRAWBERRY LEAF EXTRACT

2021 ◽  
pp. 60-65
Author(s):  
Yaborova O.V. ◽  
Sosnina S.A. ◽  
Turyshev A.Yu.
Keyword(s):  
Raw Materials ◽  
Practical Interest ◽  
Extraction Methods ◽  
Dosage Forms ◽  
Technological Parameters ◽  
Plant Raw Materials ◽  
Scientific Justification ◽  
Optimal Technology ◽  
Further Development

In recent years, there has been an increasing interest in medicines produced on the basis of medicinal plant raw materials. To improve the quality of drug supply to the population and expand the range of medicines, research is relevant to improve the efficiency of the extraction methods used, replacing infusions and decoctions with industrial products. In this regard, the study of the technological parameters of obtaining an extract from the leaves of dry strawberry is of practical interest for the further development of dosage forms with it and the formation of a scientific justification for their use in medical practice.

TO THE QUESTION OF STUDYING THE POSSIBILITIES OF USING LEAVES AND DRY STRAWBERRY EXTRACT IN MEDICINE

2020 ◽  
pp. 132-136
Author(s):  
Yaborova O. V ◽  
Kuritsyn A.V. ◽  
Kylosova I.A. ◽  
Gulyaev D.K.
Keyword(s):  
Leaf Extract ◽  
Raw Materials ◽  
Practical Interest ◽  
Dosage Forms ◽  
Practical Application ◽  
Plant Raw Materials ◽  
Scientific Justification ◽  
Medicinal Properties ◽  
The Comparative Study ◽  
Further Development

In recent years, there has been an increasing interest in medicines produced on the basis of medicinal plant raw materials. Information about the concentration of elements by medicinal plants and substances allows us to see a new aspect of their practical application, to identify new medicinal properties. In this regard, the comparative study of the elemental composition of strawberry leaves and dry strawberry leaf extract is of practical interest for the further development of dosage forms and the formation of scientific justification for their use in medical practice.

scholarly journals Pulsatilla alba: analytical review of spread, chemical composition, biological activity and medical application

2021 ◽  
pp. 10-14
Author(s):  
Anna Krvavych ◽  
Nataliia Reviakina ◽  
Lesia Zhurakhivska ◽  
Iryna Hubytska ◽  
Roksolana Konechna
Keyword(s):  
Chemical Composition ◽  
Medicinal Plant ◽  
Raw Materials ◽  
Folk Medicine ◽  
Medical Application ◽  
Biologically Active ◽  
Raw Material ◽  
Sources Of Information ◽  
Scientific Publications ◽  
Plant Raw Materials

The object of analytical study is the medicinal plant Pulsatilla alba. This species is rare, the stocks of herbal raw materials are limited, and there are no Pulsatilla alba-based medicines on the Ukrainian market. The aim of study was to analyze and summarize data on the range, content of biologically active compounds and the spectrum of use in pharmacy and medicine Pulsatilla alba. Materials and methods. Literary and electronic sources of information on the distribution, chemical composition and pharmacological activity of Pulsatilla alba. Results. Pulsatilla alba is a plant of the Ranunculaceae family, characterized by a high content of biologically active organic compounds, namely organic acids, traces of alkaloids, vitamins, resinous and tannins, about 20 different macro-and micronutrients, essential oils, γ-lactones, triterpenoids, sterols, chelidonic acid, coumarins, as well as giving it protection status make it an interesting object for research. Analysis of scientific publications revealed that plants of the family Ranunculaceae, in particular, Pulsatilla alba contain a significant amount of biologically active substances, have numerous pharmacological activities, have long been used in folk medicine, and is a promising raw material for the production of phytopreparations. The volume of processing of medicinal plant raw materials in Ukraine in one year is from 5 to 6 thousand tons, the amount of raw materials for export reaches more than 3 thousand tons per year. About 1,000 tons of raw materials consumed in Ukraine are imported and 1,500 tons are domestically produced. Conclusions. Therefore, as populations of rare low-competitive species of the Ranunculaceae family are particularly endangered, displaced by tree, shrub and highly competitive trivial violent herbaceous species due to the widespread use of Pulsatilla alba in folk medicine as an antitumor, hypnotic, hypnotic, antifungal, antifungal research which should be continued

Importance of Dietary Supplements to the Health

2020 ◽  
Vol 16 ◽  
Author(s):  
Amarnath Mishra ◽  
Arvind K. Singh Chandel ◽  
Dixit V. Bhalani ◽  
Richa Shrivastava
Keyword(s):  
Amino Acids ◽  
Fatty Acids ◽  
Dietary Supplements ◽  
Dietary Supplement ◽  
Dosage Forms ◽  
Recommended Dose ◽  
Herbal Products ◽  
Other Substances ◽  
Enzyme Supplement

: The term “dietary supplement” defines a comprehensive and diverse category of products that are essential to our health but those are absent or insufficient into the diet that may be needed to take separately, requirement of dietary supplements are varies at different stages of life such as infant, child-adult, pregnancy, lactation, and geriatrics. Dietary supplements are not medicines, nor should they be considered a substitute for food. USFDA defines dietary supplements in part as a product taken by mouth that contains a “dietary ingredients.” Nutritional ingredients comprise vitamins, minerals, amino acids, and herbs or botanicals, in addition to other substances that can be considered to supplement the diet. The market flooded with various dosage forms of dietary supplements such as capsules, tablets, powders, energy bars, liquids, etc. These include Vitamin, Mineral, Herbal Products containing extracts from herbs as well as algae and fungi, Concentrate, metabolite, constituent, or extract, Enzyme supplement, Essential amino, and fatty acids. This chapter describes the importance of the dietary supplement, source, disease arises by deficiency, and recommended dose for different groups.

Validation and optimization of qPCR method for identification of Actaea Racemosa (Black cohosh) NHPs

2020 ◽  
Author(s):  
Jeevitha Shanmughanandhan ◽  
Dhivya Shanmughanandhan ◽  
Subramanyam Ragupathy ◽  
Thomas A Henry ◽  
Steven G Newmaster
Keyword(s):  
Dietary Supplements ◽  
Raw Materials ◽  
Black Cohosh ◽  
Powder Materials ◽  
Target Species ◽  
Herbal Products ◽  
Hydrolysis Probe ◽  
Actaea Racemosa ◽  
Probe Assay ◽  
Species Specific

Abstract BACKGROUND Actaea racemosa (Black cohosh) herbal dietary supplements are commonly used to treat menopausal symptoms in women. However, there is a considerable risk of contamination of A. racemosa herbal products in the natural health product (NHP) industry, impacting potential efficacy. Authentication of A. racemosa products is challenging because of the standard, multi-part analytical chemistry methods that may be too costly and not appropriate for both raw and finished products. OBJECTIVE In this paper, we discuss about developing and validating quick alternative biotechnology methods to authenticate A. racemosa herbal dietary supplements, based on the use of a species-specific hydrolysis PCR probe assay. METHODS A qPCR based species-specific hydrolysis probe assay was designed, validated, and optimized for precisely identifying the species of interest using the following analytical validation criteria: (1) specificity (accuracy) in determining the target species ingredient, while not identifying other non-target species, (2) sensitivity in detecting the smallest amount of the target material, and (3) reliability (repeatability and reproducibility) in detecting the target species in raw materials on a real-time PCR platform. RESULTS The results show that the species-specific hydrolysis probe assay was successfully developed for the raw materials and powders of A. racemosa. The specificity of the test was 100% to the target species. The efficiency of the assay was observed to be 99%, and the reliability of the assay was 100% for the raw/starting and powder materials. CONCLUSION The method developed in this study can be used to authenticate and perform qualitative analysis of A. racemosa supplements.

Skuteczność i bezpieczeństwo stosowania korzenia Symphytum officinale L. – przegląd danych literaturowych

2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Katarzyna Kimel ◽  
Mirosława Krauze-Baranowska
Keyword(s):  
Clinical Trials ◽  
Chemical Composition ◽  
Raw Materials ◽  
Biologically Active ◽  
Herbal Products ◽  
Plant Raw Materials ◽  
Beneficial Effects ◽  
History Of ◽  
Ancient Times ◽  
History Of Use

Comfrey root – Symphyti radix has been present in medicine since ancient times. Nowadays, European Medicine Agency (EMA) restricts its only for external use, in short therapies not exceeding 10 days. The last decade has been characterized by the progress in research on the chemical composition and metabolism of biologically active compounds present in the root and leaves. The result is the presence of herbal medicinal products containing comfrey root extracts with reduced content or free of toxic pyrrolizidine alkaloids on the European market of herbal products. Moreover, the medicinal properties of leaves from another Symphytum species, namely Russian comfrey, are also in the use. The results of clinical trials indicate the beneficial effects of plant raw materials obtained from comfreys in musculoskeletal system disorders – comfrey root and skin inflammations – leaves of Russian comfrey. The paper presents the history of use, chemical composition, therapeutic effect and toxicity of comfrey, as well as characterizes clinical trials on products containing comfrey extracts from root and leaves.

COMPARATIVE ANALYSIS OF BIOACTIVE SUBSTANCES CONTENT IN THE LEAVES AND FRUITS OF A ROWAN-TREE (SORBUS AUCUPARIA FRUCTUS) AND ASSESSMENT OF PROSPECTS IN MEDICINE AND PHARMACY

2020 ◽  
pp. 58-62
Author(s):  
Chernichkina A.D.
Keyword(s):  
Raw Materials ◽  
Wide Distribution ◽  
Biologically Active ◽  
Bioactive Substances ◽  
Plant Raw Materials ◽  
Mountain Ash ◽  
The Russian Federation ◽  
Materials Used ◽  
Active Substances ◽  
Pectin Substances

A large number of biologically active substances, organic acids, tannins, and pectin substances were detected during the study of fruits, leaves, and pulp of the fruits of mountain Ash. The content of these substances in leaves and pulp will significantly expand the arsenal of medicinal plant raw materials used. Given the wide distribution of mountain Ash in the territory of the Russian Federation, harvesting leaves from the same plants after harvesting the fruit and using pulp will make it possible to obtain new phytopreparations.

Sign in / Sign up

Export Citation Format

Share Document