scholarly journals Correlation analysis of clinical and medical history records of married couples receiving infertility treatment

2021 ◽  
pp. 84-93
Author(s):  
I. S. Fedorov ◽  
Ju. S. Drapkina ◽  
N. N. Lobanova ◽  
N. P. Makarova ◽  
A. V. Timofeeva
Keyword(s):  
Medical History ◽  
Ovarian Stimulation ◽  
Married Couple ◽  
Married Couples ◽  
Surgical Removal ◽  
Fallopian Tubes ◽  
High Concentration ◽  
Male Factor ◽  
Art Programs ◽  
Art Program

Introduction. Despite the availability of general principles and regimens for ovarian stimulation on the assisted reproductive technology (ART) programs, an individual situational modification is required in each specific case.Objective. To optimize the ovarian stimulation protocols on the ART program based on the clinical and medical history records of the married couple.Materials and methods.The clinical and medical history records, as well as the stimulation cycle parameters of 60 married couples were analysed. The married couples enrolled in this study were diagnosed with infertility caused by tubo-peritoneal (44 married couples), male (5 married couples), combined factor (6 married couples), as well as external genital endometriosis combined with a male factor (3 married couples), and tubo-peritoneal factor (2 married couples). All married couples underwent IVF/ICSI procedures under the gonadotropin-releasing hormone antagonist (GnRH-ant) protocol and ovarian stimulation on day 2 or 3 of the menstrual cycle.Results. All married couples were divided into two groups: 38 couples with a negative implantation result and 20 married couples with positive implantation results. The surgical removal of fallopian tubes has been shown to be inversely correlated with the duration of infertility. The use of hCG positively correlates to the ratio of mature oocytes and oocyte-cumulus complexes (OCC) and the onset of pregnancy. A reduced percentage of morphologically healthy sperm with an overall high concentration of sperm in the ejaculate can be interpreted as fertile sperm.Conclusions. During ovarian stimulation on the ART program, special attention should be paid to the duration of stimulation, the types of interventions for triggering final oocyte maturation and the total gonadotropin dose. A differentiated approach to conducting the surgical removal of fallopian tubes is required. The reduced percentage of morphologically healthy sperm with an overall high concentration of sperm in the ejaculate serves as a favourable prognostic factor for the outcome of ART programs.

Suboptimal response to controlled ovarian stimulation in IVF / ICSI cycles

2021 ◽  
Vol 69 (6) ◽  
pp. 61-70
Author(s):  
Cong Tuan Nguyen ◽  
Dariko A. Niauri ◽  
Lyailya Kh. Dzhemlikhanova ◽  
Igor Yu. Kogan ◽  
Inna O. Krikheli ◽  
...  
Keyword(s):  
Pregnancy Rate ◽  
Ovarian Reserve ◽  
Ovarian Stimulation ◽  
Uterine Fibroids ◽  
Negative Influence ◽  
Clinical Pregnancy ◽  
Clinical Pregnancy Rate ◽  
Controlled Ovarian Stimulation ◽  
Male Factor ◽  
Art Programs

Hypothesis/Aims of study. Currently, the frequency of suboptimal response (4-9 retrieved oocytes) to controlled ovarian stimulation (COS) in woman is quite high; however, its efficacy is poorly studied. The aim of this study was to evaluate the main characteristics of IVF / ICSI programs in patients with a suboptimal response to COS. Study design, materials and methods. We performed a retrospective study of 412 IVF / ICSI cycles in women with a suboptimal response to COS, including a comparative analysis of clinical and embryological parameters, ovarian reserve and the efficacy of IVF / ICSI protocols. Results. Clinical pregnancy rate in ovarian stimulation cycles with a suboptimal response to COS was 27.9%. The efficacy of assisted reproductive technology (ART) programs in women with uterine fibroids was significantly lower than in patients without fibroids (19.1% vs. 30.5%, p = 0.03; OR = 0.54; 95% CI: 0.31-0.95). Clinical pregnancy rate in patients with male factor infertility was significantly higher than in women with anovulation (37.1% vs. 20.9%, р = 0.005; OR = 2.24; 95% CI: 1.27-3.94) or tubal factor infertility (37.1% vs. 24.8%, р = 0.02; OR = 1.79; 95% CI: 1.09-2.94). There were significant correlations between the number of retrieved oocytes with serum anti-Mllerian hormone (AMH) concentration (r = 0.32, p 0.001) and antral follicle count (AFC) (r = 0.38, p 0.001). In addition, the need for follicle-stimulating hormone (FSH) preparations during COS correlated significantly with ovarian reserve parameters (AMH and AFC) (r = 0.45 and 0.44, both p 0.001, respectively) and the age of patients (r = 0.47; p 0.001). Conclusion. The clinical pregnancy rate in women with a suboptimal response to COS was low. Concomitant uterine fibroids represented an additional factor of negative influence on IVF / ICSI outcomes in women with a suboptimal response to COS. The male factor of infertility in patients with a suboptimal response did not reduce the efficacy of ART programs. Ovarian reserve parameters in women with a suboptimal response correlated with the need for FSH preparations during COS and the number of retrieved oocytes.

scholarly journals Modern Algorithm for Diagnosis and Treatment of Diseases in Men That Lead to Infertility

Health of Man ◽  
2021 ◽  
pp. 8-14
Author(s):  
Oleh Nikitin ◽  
Mykola Yasynetsky
Keyword(s):  
Married Couple ◽  
Married Couples ◽  
Reproductive Technologies ◽  
Reproductive Age ◽  
Diagnosis And Treatment ◽  
Male Factor ◽  
Internal Organs ◽  
Child Treatment ◽  
Literary Sources ◽  
The World

The problem of sterile marriage provides great importance throughout the world. Infertility is a condition that is accompanied by a number of diseases of the genital organs and systemic diseases of the male or female organism. According to various literary sources, about 50–100 million people suffer from infertility in the world, that is, one out of 5–7 couples of reproductive age suffers from infertility. The problem of infertility in marriage is of particular importance in the context of the demographic crisis in Ukraine, where the frequency of infertile marriage among married couples of reproductive age is 10,0–15,0 %, and in some regions this indicator is close to 20,0 %. In Ukraine, there are more than 1 million infertile married couples, the male factor in the structure of infertility is about 40-50 % of cases. Most authors point to the polyetiology of male infertility. In its development, a significant role is assigned to such factors as neuropsychic, infectious toxic, congenital and genetic reasons, exogenous and habitual intoxications, ionizing radiation, dysfunctions of the endocrine glands and other internal organs, exposure to temperatures, vascular disorders, damage to the genital organs and their autoimmune lesions. Infertility is a complex and multifaceted problem, and there are a lot of different questions which need to solve. Particular difficulties arise in determining the treatment tactics in cases where there is a combination of various causes of infertility in a married couple. Opportune examination of partners with using modern hardware, laboratory and genetic methods is very important, and it allows to prescribe an effective treatment. The use of reproductive technologies significantly expands the possibilities for solving the problem of infertility. However, their main purpose is the birth of a child; treatment of diseases that have led to infertility requires additional efforts. In this regard, the development of modern methods of diagnosis and treatment of sterile marriage remains one of the actual problems.

scholarly journals Pathogenetic significance of the male factor in an uncompleted pregnancy

2021 ◽  
Vol 20 (3) ◽  
pp. 27-32
Author(s):  
E. V. Kudryavtseva ◽  
N. N. Potapov ◽  
V. V. Kovalev
Keyword(s):  
Chronic Diseases ◽  
Chromosomal Abnormalities ◽  
Married Couple ◽  
Married Couples ◽  
Control Group ◽  
Male Factor ◽  
Pregnancy Failure ◽  
History Of ◽  
Group 2 ◽  
Group 1

Introduction. When pregnancy failure occurs, not only the woman should be examined, but also her partner. Purpose of the study — to evaluate the significance of spermogram values in the partners of patients with an uncompleted pregnancy. Materials and methods. A retrospective comparative cohort study was conducted. A total of 197 married couples were ncluded in the study. Group 1 consisted of 71 couples with a history of miscarriag. Chromosomal abnormalities (CA) were detected during embryo cytogenetic examination in 45 cases; these patients were included in subgroup 1a; the rest constituted subgroup 1b. The control group (group 2) consisted of 126 couples without a history of pregnancy loss. A detailed anamnesis and general clinical examinations were performed in all the couples. Spouses of the patients underwent spermogram analysis. Results. The proportion of men who abused alcohol was higher in group 1 than in group 2 — 40.8% vs. 19% (p<0.01). In subgroup 1b chronic diseases were noted in 61.5% of men, in group 2 — only 28.6% (p<0.001). Differences in the number of men with normal spermogram were found between group 2 and subgroup 1b, 65.1% and 35.3%, respectively (p=0.036). In group 1, 45% of men had teratozospermia (43.5% in subgroup 1a, 47.1 in subgroup 1b) and in group 2, only 16.3% (p=0.004). Discussion. In most cases, the leading etiological factor in pregnancy failure is a chromosomal abnormality n the embryo (fetus). The role of the "male" factor is increasing in the genesis of pregnancy failure. Examination of thspouse should be an integral component of pre-conceptional preparation. Conclusion. Spousal alcohol abusrisk factor for CA in the embryo and for pregnancy failure. The presence of chronic diseases in the spouse is also a risk factor for pregnancy failure. Among the spermogram parameters, the number of spermatozoa with normal morphology is the most significant in assessing the ririsk of pregnancy failure in a married couple, teratozoospermia significantly increases the risk of non-pregnancy.

PHUBBING BEHAVIOR AND ROMANTIC RELATIONSHIP: MECHANISM OF MENTAL HEALTH AMONG MARRIED COUPLES

2020 ◽  
Vol 4 (1) ◽  
pp. 103-137
Author(s):  
Rabia Zonash Mir
Keyword(s):  
Mental Health ◽  
Romantic Relationship ◽  
Rating Scale ◽  
Short Form ◽  
Married Couple ◽  
Married Couples ◽  
Mental Health Issue ◽  
Health Issues ◽  
Arranged Marriage ◽  
Love Marriage

Does Phubbing Behavior and Romantic Relation leads to Mental Health issues among married couple? The present study intended to explore the effect of how phubbing behavior and romantic relationships are affecting mental health of married couples. For the study purpose a sample of 120 Married couples were taken between the age ranges 20-60 years of age. Partner Phubbing Rating Scale developed by Roberts and David (2015) was used to measure phubbing behavior among married couples. Romantic Partner Scale (RPS) developed by Zacchilli, Hendricks, and Hendricks, (2012) was applied to assess the romantic relationship between both partners and the third scale used was short form of Mental Health Continuum developed by Keyes (2005) in order to assess the mental health issue among married couples. Phubbing behavior positively predicted interactional activity and negatively predicts compromise, avoidance, separation, dominance and submission. Phubbing behavior negatively predicts mental health among married couples. Gender difference indicates that males are higher on romantic relationship as well as mental health as compared to females. As far as demographic variables are concerned, based on the findings of current research, it was concluded that there was no gender differences found in phubbing behavior, romantic relationship, and mental health of married couples. Phubbing behavior is significantly higher in love marriage couples in comparison with arranged marriage couples.

scholarly journals Controlled ovarian stimulation should not be preferred for male infertility treated with intrauterine insemination: a retrospective study

2021 ◽  
Vol 19 (1) ◽  
Author(s):  
Yan Tang ◽  
Qian-Dong He ◽  
Ting-Ting Zhang ◽  
Jing-Jing Wang ◽  
Si-Chong Huang ◽  
...  
Keyword(s):  
Ectopic Pregnancy ◽  
Pregnancy Rate ◽  
Ovarian Stimulation ◽  
Intrauterine Insemination ◽  
Multiple Pregnancy ◽  
Clinical Pregnancy ◽  
Male Factor Infertility ◽  
Male Factor ◽  
Ovulatory Follicles ◽  
Multiple Pregnancy Rate

Abstract Background Some studies have stated that intrauterine insemination (IUI) with controlled ovarian stimulation (COS) might increase the pregnancy rate, while others suggest that IUI in the natural cycle (NC) should be the first line of treatment. It remains unclear whether it is necessary to use COS at the same time when IUI is applied to treat isolated male factor infertility. Thus, we aimed to investigate efficacy of IUI with COS for isolated male factor infertility. Methods A total of 601 IUI cycles from 307 couples who sought medical care for isolated male factor infertility between January 2010 and February 2020 were divided into two groups: NC-IUI and COS-IUI. The COS-IUI group was further divided into two subgroups according to the number of pre-ovulatory follicles on the day of HCG: cycles with monofollicular development (one follicle group) and cycles with at least two pre-ovulatory follicles (≥ 2 follicles group). The IUI outcomes, including clinical pregnancy, live birth, spontaneous abortion, ectopic pregnancy, and multiple pregnancy rates were compared. Results The clinical pregnancy, live birth, spontaneous abortion, and ectopic pregnancy rates were comparable between the NC-IUI and COS-IUI group. Similar results were also observed among the NC-IUI, one follicle, and ≥ 2 follicles groups. However, with respect to the multiple pregnancy rate, a trend toward higher multiple pregnancy rate was observed in the COS-IUI group compared to the NC-IUI group (8.7% vs. 0, P = 0.091), and a significant difference was found between the NC-IUI and ≥ 2 follicles group (0 vs. 16.7%, P = 0.033). Conclusion In COS cycles, especially in those with at least two pre-ovulatory follicles, the multiple pregnancy rate increased without a substantial gain in overall pregnancy rate; thus, COS should not be preferred in IUI for isolated male factor infertility. If COS is required, one stimulated follicle and one healthy baby should be the goal considering the safety of both mothers and foetuses.

scholarly journals The ratio of exogenous Luteinizing hormone to Follicle stimulating hormone administered for controlled ovarian stimulation is associated with oocytes’ number and competence

2020 ◽  
Vol 40 (1) ◽  
Author(s):  
Dragos Albu ◽  
Alice Albu
Keyword(s):  
Luteinizing Hormone ◽  
Ovarian Stimulation ◽  
Follicle Stimulating Hormone ◽  
Fertilization Rate ◽  
Controlled Ovarian Stimulation ◽  
Human Menopausal Gonadotropin ◽  
Male Factor ◽  
Entire Study ◽  
Stimulating Hormone

Abstract We performed a retrospective study aiming to study the relationship between the ratio of the exogenous luteinizing hormone to follicle stimulating hormone (LH/FSH) administrated for controlled ovarian stimulation (COS) and the number and competence of the oocytes retrieved for in vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI). Eight hundred sixty-eight consecutive infertile patients (mean age 34.54 ± 4.01 years, mean anti-Müllerian hormone (AMH) 2.94 ± 2.07 ng/ml) treated with long agonist protocol and a mixed gonadotropin protocol (human menopausal gonadotropin in association with recombinant FSH (recFSH)) who performed IVF/ICSI between January 2013 and February 2016, were included. Patients with severe male factor were excluded. LH/FSH was calculated based on total doses of the two gonadotropins. We found, after adjustment for confounders, a positive relationship between LH/FSH and the retrieved oocytes’ (β = 0.229, P&lt;0.0001) and zygotes’ number (β = 0.144, P&lt;0.0001) in the entire study group and in subgroups according to age (&lt;35 and ≥35 years) and ovarian reserve (AMH &lt; 1.1 and ≥ 1.1 ng/ml). The fertilization rate was positively associated with LH/FSH in patients with LH/FSH in the lowest three quartiles (below 0.77) (β = 0.096, P=0.034). However, patients in the fourth quartile of LH/FSH had a lower fertilization rate as compared with patients in quartiles 1–3 which, after adjustment for covariates, was only marginally negatively related with LH/FSH (β = −0.108, P=0.05). In conclusion, our results suggest that the adequate LH/FSH administrated during COS can improve the oocytes’ and zygotes’ number in IVF/ICSI cycles, but also the fertilization rate when a certain proportion of LH/FSH is not exceeded.

scholarly journals Features of the Role Structure and Relationships in Korean and Russian Couples

2020 ◽  
Vol 14 (2) ◽  
pp. 137-149
Author(s):  
Vlada Pishchik ◽  
Irina Li
Keyword(s):  
Married Couple ◽  
Married Couples ◽  
Family Counseling ◽  
Psychological Climate ◽  
Modern World ◽  
Financial Responsibility ◽  
Family Attitudes ◽  
Role Structure ◽  
Korean Families ◽  
Internal Arrangement

The modern world leads to collapse of the marriage institution. It causes a lot of problems. One of them raises the question of how ethnic culture preserves the relationships in married couples within traditional framework if these couples live in a different national cultural; environment. Both Russian and Korean are collectivism cultures. However, in Russia individualism is spreading very quickly among young people. In Korean families elderly people have a big influence, they adhere to Confucianism. Russians have more democratic relations and adhere to Christianity. We tried to prove that Korean couples still have traditional marital roles, relationships, and attitudes. The purpose of the study is to compare the role structure, features of the husband-wife relationship, and attitudes in the Russian and Korean married couples living in Russia. Russian and Korean family roles are considered in the article, as well as the features of family attitudes that characterize the type of family and describe the mentality of Russians and Koreans. A comparative cross-methodology was applied within pairs and between Korean and Russian pairs, and data was factorized. The sample consisted of n = 80 participants. We used the following methods: measurement of roles in a family; study of understanding relationships, emotional attraction and authoritarianism; attitudes towards love, children, money, and divorce. The scientific novelty of the research is expressed in the fact that the comparison with various aspects of the structure of roles and relationships in modern Korean and Russian couples is carried out, the members of married couples of both nationalities are compared. The study showed that Russians and Koreans living in Russia have become very similar in their lifestyle, but they differ in the internal arrangement of the family, role preferences and attitudes in a married couple, especially in relation to children, sex, psychological climate and financial responsibility. The data obtained can be used in family counseling and therapy.

Engaging Communities through an Art Program at a Domestic Violence Shelter

2021 ◽  
pp. 1366-1393
Author(s):  
Elzbieta T. Kazmierczak
Keyword(s):  
Domestic Violence ◽  
Battered Women ◽  
Fund Raising ◽  
Grant Writing ◽  
Art Programs ◽  
Domestic Violence Shelter ◽  
Art Program ◽  
Student Volunteers ◽  
Visual Artist ◽  
Set Up

This chapter is a case study, written from the perspective of a visual artist, designer, and educator, reflecting on a five-year volunteer initiative of developing, leading, and funding an art program at a domestic violence shelter for battered women and adolescent girls who experienced sexual violence. One purpose of this chapter is to provide information about establishing art programs that can be sustained by the institutions in which they are introduced. This chapter discusses the following aspects: 1) breaking the ice and establishing rapport; 2) training and supervising staff and student volunteers; 3) fund-raising, grant writing, and seeking support both within and outside the agency; 4) partnering with organizations or community groups to set up art exhibitions; 5) partnering with artists and writers to print and distribute an educational publication; and 6) developing research with vulnerable populations serviced by the agency.

Marital Satisfaction Among Taiwanese Young Married Couples: The Effects of Resources and Traditional Norms

2019 ◽  
Vol 40 (14) ◽  
pp. 2015-2043
Author(s):  
Chin-Chun Yi ◽  
Wen-Hsu Lin ◽  
Josef Kuo-Hsun Ma
Keyword(s):  
Marital Satisfaction ◽  
Married Couple ◽  
Married Couples ◽  
Negative Influence ◽  
Resource Theory ◽  
Cultural Norms ◽  
Full Time ◽  
Continuity And Change ◽  
Cultural Perspectives ◽  
Traditional Norms

This study aims to illustrate the importance of cultural norms for marital satisfaction among young married Taiwanese couples. Data are taken from the Taiwan Youth Project, a longitudinal panel since the year of 2000, with 401 married couple data completed in 2015. Based on the resource theory and contextual cultural perspectives, results confirm that both resources and cultural factors produce significant effects on young couple’s marital satisfaction. As proposed, cultural norms have greater impact on wife’s marital satisfaction. The patrilocal coresidence between generations is especially harmful for wives with full-time job, while negative in-law relations reported by husbands produce more powerful negative influence on the couples. However, gender of the child does not attain expected significance. Findings suggest that both continuity and change of family dynamics is occurring in Taiwan. Future studies need to consider both cultural norms and individual resources in analyzing marital relations in changing East Asian societies.

Recurrent Empty Follicle Syndrome: A Rare Entity

2016 ◽  
Vol 7 (1) ◽  
pp. 32-36
Author(s):  
Thankam Rama Varma
Keyword(s):  
Ovarian Stimulation ◽  
Rare Event ◽  
Oocyte Donation ◽  
Normal Male ◽  
Rare Entity ◽  
Male Factor ◽  
Vitro Fertilization ◽  
Follicular Aspiration ◽  
Empty Follicle Syndrome

ABSTRACT Failure to aspirate oocytes from apparently normally growing ovarian follicles with normal steroidogenesis after ovarian stimulation and meticulous follicular aspiration is referred to as empty follicle syndrome (EFS). It is a rare event in in vitro fertilization (IVF), but the economical consequences and emotional frustration of a cancelled cycle are enormous, as it causes substantial stress for both the patients and the treating physician. Here, we have reported one patient of recurrent EFS who had IVF in view of previous failed intrauterine inseminations, with normal male factor. Two cycles of controlled ovarian stimulation were done using antagonist protocol for this patient. However, as we were unable to retrieve any oocytes in both the cycles, we were offered her oocyte donation as the last resort. How to cite this article Punhani R, Shankar K, Varma TR. Recurrent Empty Follicle Syndrome: a Rare Entity. Int J Infertil Fetal Med 2016;7(1):32-36.

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