Estimation of geographical variation of cancer risks in drinking water in Japan

2006 ◽  
Vol 6 (2) ◽  
pp. 31-37
Author(s):  
K. Ohno ◽  
E. Kadota ◽  
Y. Kondo ◽  
T. Kamei ◽  
Y. Magara

The cancer risks posed by ten substances in raw and purified water were estimated for each municipality in Japan to compare risks between raw and purified water, and inter-municipality. Water concentrations were estimated by use of statistical data. Assigning cancer unit risks to each substance and applying the assumption of additive toxicological effects to multiple carcinogens, total cancer risks of the waters were estimated. As a result, the geometric means of total cancer risks in raw and purified water were 1.16×10−5 and 2.18×10−5, respectively. In raw water, the contribution ratio of arsenic to total cancer risk accounted for 97%. In purified water, that of four trihalomethanes (THMs) accounted for 54%. The increase of total cancer risks in purified water was due to THMs. In regard to the geographical variation, the relationship between population size and total cancer risks were investigated. The result was that there were higher cancer risks in the big cities with the population more than a million both in raw and purified water. One plausible reason for the higher risks in purified water in the big cities is a larger chlorination dose due to the huge water supply areas. The reason for the increase in raw water remained unclear.

Author(s):  
Marco Mele ◽  
Cosimo Magazzino ◽  
Nicolas Schneider ◽  
Floriana Nicolai

AbstractAlthough the literature on the relationship between economic growth and CO2 emissions is extensive, the use of machine learning (ML) tools remains seminal. In this paper, we assess this nexus for Italy using innovative algorithms, with yearly data for the 1960–2017 period. We develop three distinct models: the batch gradient descent (BGD), the stochastic gradient descent (SGD), and the multilayer perceptron (MLP). Despite the phase of low Italian economic growth, results reveal that CO2 emissions increased in the predicting model. Compared to the observed statistical data, the algorithm shows a correlation between low growth and higher CO2 increase, which contradicts the main strand of literature. Based on this outcome, adequate policy recommendations are provided.


Transport ◽  
2012 ◽  
Vol 26 (4) ◽  
pp. 418-424 ◽  
Author(s):  
Valentina Basarić ◽  
Jadranka Jović

The research presented in this paper is aimed at defining a model that enables the management of the relationship between private vehicles and public transport applying the available instruments of city transport policy such as parking policy and public transport policy measures. Statistical data used for modelling is sourced from the database in a wide range of EU cities. The target model was developed in the form of stepwise regression analysis. Very favourable statistical results were obtained, and the subsequent tests on the city of Novi Sad (250000 inhabitants) led to the conclusion that the obtained results were suitable for implementation in practice. The results of the implemented procedure are of great importance for the enhancement of the existing transport policies in cities, as they enable the development of strategies for finding combinations of instruments that would bring the transport system and urban environment into a desired-viable rather than consequential condition.


2018 ◽  
Vol 18 (1) ◽  
pp. 124-154
Author(s):  
Dimitris Papazachariou ◽  
Anna Fterniati ◽  
Argiris Archakis ◽  
Vasia Tsami

Abstract Over the past decades, contemporary sociolinguistics has challenged the existence of fixed and rigid linguistic boundaries, thus focusing on how the speakers themselves define language varieties and how specific linguistic choices end up being perceived as language varieties. In this light, the present paper explores the influence of metapragmatic stereotypes on elementary school pupils’ attitudes towards geographical varieties. Specifically, we investigate children’s beliefs as to the acceptability of geographical varieties and their perception of the overt and covert prestige of geographical varieties and dialectal speakers. Furthermore, we explore the relationship between the children’s specific beliefs and factors such as gender, the social stratification of the school location and the pupils’ performance in language subjects. The data of the study was collected via questionnaires with closed questions. The research findings indicate that the children of our sample associate geographical varieties with rural settings and informal communicative contexts. Moreover, children recognize a lack of overt prestige in geographical variation; at the same time, they evaluate positively the social attractiveness and the personal reliability of the geographical varieties and their speakers. Our research showed that pupils’ beliefs are in line with the dominant metapragmatic stereotypes which promote language homogeneity.


2015 ◽  
Vol 48 (2) ◽  
pp. 51-60 ◽  
Author(s):  
Y. Shiri ◽  
M. Solouki ◽  
M. Forootan

AbstractIn order to study the allelic variation of Glu-1 gene (High molecular weight glutenin), 100 Iranian wheat cultivars including imported and domestic genotypes were analyzed using ALP-PCR technique. Four specific primer pairs were used based on the genetic loci of Glu-A1, Glu-B1, and Glu-D1 to perform the chain polymerase reactions. PCR reaction products were resolved on 2% agarose gel. Since allele “a” had the largest relative frequency (0.707), two alleles (a 344bp; b 362bp) were identified by P1-P2 primer for Glu-A1 locus. Three alleles (a 800bp; b 500bp; c 300bp) were detected for Glu-B1 locus by P5-P6 primer, and allele “b” was assumed as the highest relative frequency (0.618). Two primer pairs were applied for Glu-D1 locus. Ultimately, four alleles were identified, where allele “c” had the highest relative frequency (0.525). The observed genetic variation value for Glu-D1 locus (H=0.648) exhibits the maximal polymorphism. Using cluster analysis, the relationship between the observed polymorphism and geographical variation was investigated. The results indicated that there exists a remarkable variation in Glu- A1 locus between the Iranian wheat cultivars.


2021 ◽  
Vol 213 (10) ◽  
pp. 75-80
Author(s):  
E. Razhina

Abstract. The aim of this work is to investigate the relationship between indicators of cicatricial digestion and linearity of cows. Methods. The research was carried out in the breeding enterprises of the Sverdlovsk region on the livestock of Ural-type cows. Cicatricial fluid was collected with an oropharyngeal rubber probe, and a wooden yaw was also used. Cicatricial content was assessed at the Chelyabinsk Interregional Veterinary Laboratory. The pH value was determined by the electrometric method, VFA – in the Markgam apparatus, ammonia – by the microdiffusion method. Ciliates – in Goryaev’s chamber and under a microscope, bacteria – under a microscope with the addition of sodium chloride solution. Statistical data processing was carried out in the Microsoft Office Excel 2010 program. Results. In terms of the number of ciliates and bacteria in the rumen fluid, the Montwick Chieftain cows, characterized by high productive qualities, had an advantage. In terms of pH and VFA, the Vis Back Ideal line was the best. There were no significant differences between the groups in terms of the amount of ammonia in the rumen. The best animals from the point of view of influence on cicatricial metabolism were the animals of the Vis Back Ideal and Montwick Chieftain lineage. Scientific novelty. Studies have shown that linearity is associated with cicatricial digestion in cows. The relationship of bull lines with indicators of cicatricial metabolism of cows has been determined for the first time. The food in the rumen is digested due to the action of bacteria, ciliates, and fungi. An environment has been created in the rumen for the active development of microflora. Bacteria are able to synthesize amino acids and vitamins. The proventriculus can contain up to 50 species of ciliates.


2001 ◽  
Vol 82 (6) ◽  
pp. 464-465
Author(s):  
V. P. Bulatov ◽  
A. V. Ivanov ◽  
N. V. Rylova

The aim of our research was to establish the relationship between the quality composition of drinking water and indicators of the state of gastroduodenal organs in children. We analyzed the incidence of diseases of the digestive organs according to the reporting and statistical data for the period from 1995 to 1999.


Author(s):  
Anar Eminov Et al.

According to the statistical data of recent years, tourism has been one of the ever-growing sectors in Azerbaijan. Thus, in the last five years, there has been a steady increase in the number of entrepreneurship subjects serving tourism in Azerbaijan and the number of foreign nationals traveling for tourism, correspondingly 4.5 and 8.5 percent. At present, the direct share of the tourism industry in the country's GDP and employment is 4.5 and 3.3 percent, respectively. In the article econometric analysis of the dependence on the relationship between tourism industry graduates and their development has been done. The regression equation of the dependence of the number of graduates studying tourism on the number of tourists in the country and the dependence of the tourism sector’s GDP on the number of graduates in the tourism sector were estimated using the Eviews software based on 2008–2017 statistical data using the least squares method.


2019 ◽  
Vol 1 (2) ◽  
pp. 33-38

Introduction: Cancer is one of the most common causes of death among females. In our research, cancer data were collected in Wasit Governorate for patients who were referred to Al-Zahra Educational Hospital for the period From February 2010 to February 2019. The results showed that breast cancer is the most common type of cancer in Wasit governorate and by percentage (35.4%) with 341 out of 966 cases of cancer. Methods: Data were collected from data base between the year (2010 to 2019), with the highest rate of cases in 2013, which isaround 139 cases , of these cases around 71 were breast cancer (51.07% recurrence). Surprisingly the lowest cases were recorded in a year after (2014) with total cancer cases of 65 from them 21 cases of breast cancer only. Results: About the relationship between breast cancer and gender, breast cancer recorded 95.60% of the cases in females, while percentage of men cases only 4.39%. Conclusion: The higher percentage of the cases were around 40- 49 years old , 92 cases (27%) , 80 cases (23.5%) were in the age group (50-59 years) and 65cases (19%) were in the age group (30-39 years) and 51 cases (15%) were in the age group (60-69 years) ). The lowest percentage of breast cancer was in the 10-19 age group, with only two cases (0.5%).


2007 ◽  
Vol 5 (4) ◽  
pp. 511-522 ◽  
Author(s):  
Lucy Semerjian ◽  
John Dennis

The toxicological risks and lifetime cancer risks of trihalomethanes through oral ingestion, dermal absorption, and inhalation exposure from tap water in selected regions in Lebanon are estimated. Existing trihalomethane concentrations do not pose any non-carcinogenic and developmental risks in the exposed population via oral ingestion. Among the three pathways, residents have a higher risk of cancer through oral ingestion than through the other two pathways. The lifetime cancer risk through oral ingestion for dibromochloromethane makes the highest contribution to total risks, followed by bromodichloromethane, bromoform, and chloroform. The total multipathway cancer risk analysis suggests that no cancer risks exist during the summer and winter seasons; however, in the spring the total cancer risks exceeds the USEPA acceptable level of 10−6 by a factor of 10.7.


2018 ◽  
Vol 38 (3) ◽  
Author(s):  
Lei Pi ◽  
Lanyan Fu ◽  
Yufen Xu ◽  
Di Che ◽  
Qiulian Deng ◽  
...  

Kawasaki disease (KD) is a type of disease that includes the development of a fever that lasts at least 5 days and involves the clinical manifestation of multicellular vasculitis. KD has become one of the most common pediatric cardiovascular diseases. Previous studies have reported that miR-218 rs11134527 A>G is associated with susceptibility to various cancer risks. However, there is a lack of evidence regarding the relationship between this polymorphism and KD risk. The present study explored the correlation between the miR-218 rs11134527 A>G polymorphism and the risk of KD. We recruited 532 patients with KD and 623 controls to genotype the miR-218 rs11134527 A>G polymorphism with a TaqMan allelic discrimination assay. Our results illustrated that the miR-218 rs11134527 A>G polymorphism was not associated with KD risk. In an analysis stratified by age, sex, and coronary artery lesions, we found only that the risk of KD was significantly decreased for children older than 5 years (GG vs. AA/AG: adjusted OR = 0.26, 95% CI = 0.07–0.94, P=0.041). The present study demonstrated that the miR-218 rs1113452 A>G polymorphism may have an age-related relationship with KD susceptibility that has not previously been revealed.


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